Helium poisoning: new procedure for sampling and analysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02-07

AUTHORS

Vincent Varlet, S. Iwersen-Bergmann, M. Alexandre, O. Cordes, C. Wunder, F. Holz, H. Andresen-Streichert, F. Bevalot, V. Dumestre-Toulet, S. Malbranque, T. Fracasso, S. Grabherr

ABSTRACT

An increasing number of suicidal asphyxiation with a plastic bag with inert gases, and in particular helium (He), have been reported from numerous countries over the last decade. These cases are differently managed and lead to different and variable interpretations. Based on the 12 last cases analysed in the laboratory and on the review of the most recent literature about this topic, updated autopsy guidelines for sampling have been proposed regarding to the samples choice and analytical challenges required by the gaseous state of this substance. Biological samples from airways (lungs lobe) followed by brain and cardiac blood are the best matrices to take during the autopsy to diagnose He exposure. Gaseous samples from trachea, pulmonary bronchi, gastric and cardiac areas are also recommended as alternative samples. The anatomical site of sampling must be carefully detailed, and to this end, forensic imaging constitutes a beneficial tool. Even if He detection is sufficient to conclude to He exposure, He concentrations in samples may be related to He exposure conditions (duration, breathing rate, etc.). A quantification in biological samples could be helpful to document more precisely the case. He concentrations in gaseous samples are reported up to 6.0 μmol/mL (tracheal gas), 2.4 μmol/mL (pulmonary gas), 0.64 μmol/mL (cardiac gas) and 12 μmol/mL (gastric gas). He concentrations in solid/liquid samples are reported up to 28 μmol/g (lungs) and 0.03 μmol/g (cardiac blood). The other matrices usually sampled during autopsy such as urine, peripheral blood, liver, fat matter and kidney appear as not relevant. More... »

PAGES

1-10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00414-019-02014-3

DOI

http://dx.doi.org/10.1007/s00414-019-02014-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111982508

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30734118


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00414-019-02014-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00414-019-02014-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00414-019-02014-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00414-019-02014-3'


 

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278 schema:name Faculty of Medicine, Institute of Legal Medicine, Department of Forensic Toxicology, University of Cologne, 50823, Köln, Germany
279 rdf:type schema:Organization
 




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