Prognosis of Cancer with Synchronous or Metachronous Malignant Pleural Effusion View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-12

AUTHORS

José M. Porcel, Cristina Solé, Antonieta Salud, Silvia Bielsa

ABSTRACT

PURPOSE: Malignant pleural effusions (MPE) may either coincide with or follow the diagnosis of a primary tumor. Whether this circumstance influences prognosis has not been well substantiated. METHODS: Retrospective review of all consecutive patients who were cared for at a Spanish university hospital during an 11-year period and received a diagnosis of MPE. RESULTS: Of 401 patients, the MPE was the first evidence of cancer in 265 (66%), and it followed a previously diagnosed neoplasm in 136 (34%). Lung cancer predominated in the former group (131, 50%), and breast cancer in the latter (55, 40%). MPE that were the presenting manifestation of hematological and ovarian tumors had a statistically significant survival advantage as compared to those which developed in patients from a previously known cancer (respective absolute differences of 41 and 20 months; p < 0.005). CONCLUSIONS: In hematological and ovarian malignancies, the synchronous or metachronous diagnosis of MPE may have prognostic implications. More... »

PAGES

775-779

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00408-017-0050-1

DOI

http://dx.doi.org/10.1007/s00408-017-0050-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091608655

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28900718


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