Exploring possible association between DβH genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-12

AUTHORS

Johan Isaksson, Elena L. Grigorenko, Lars Oreland, Britt af Klinteberg, Roman A. Koposov, Vladislav Ruchkin

ABSTRACT

Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania. More... »

PAGES

771-773

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00406-015-0664-3

DOI

http://dx.doi.org/10.1007/s00406-015-0664-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001040229

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26616837


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