Thyroid function and thyroid disorders during pregnancy: a review and care pathway View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02

AUTHORS

Alessandro P. Delitala, Giampiero Capobianco, Pier Luigi Cherchi, Salvatore Dessole, Giuseppe Delitala

ABSTRACT

PURPOSE: To review the literature on thyroid function and thyroid disorders during pregnancy. METHODS: A detailed literature research on MEDLINE, Cochrane library, EMBASE, NLH, ClinicalTrials.gov, and Google Scholar databases was done up to January 2018 with restriction to English language about articles regarding thyroid diseases and pregnancy. RESULTS: Thyroid hormone deficiencies are known to be detrimental for the development of the fetus. In particular, the function of the central nervous system might be impaired, causing low intelligence quotient, and mental retardation. Overt and subclinical dysfunctions of the thyroid disease should be treated appropriately in pregnancy, aiming to maintain euthyroidism. Thyroxine (T4) replacement therapy should reduce thyrotropin (TSH) concentration to the recently suggested fixed upper limits of 2.5 mU/l (first and second trimester) and 3.0 mU/l (third trimester). Overt hyperthyroidism during pregnancy is relatively uncommon but needs prompt treatment due to the increased risk of preterm delivery, congenital malformations, and fetal death. The use of antithyroid drug (methimazole, propylthiouracil, carbimazole) is the first choice for treating overt hyperthyroidism, although they are not free of side effects. Subclinical hyperthyroidism tends to be asymptomatic and no pharmacological treatment is usually needed. Gestational transient hyperthyroidism is a self-limited non-autoimmune form of hyperthyroidism with negative antibody against TSH receptors, that is related to hCG-induced thyroid hormone secretion. The vast majority of these patients does not require antithyroid therapy, although administration of low doses of β-blocker may by useful in very symptomatic patients. CONCLUSIONS: Normal maternal thyroid function is essential in pregnancy to avoid adverse maternal and fetal outcomes. More... »

PAGES

327-338

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00404-018-5018-8

DOI

http://dx.doi.org/10.1007/s00404-018-5018-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110764151

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30569344


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Azienda Ospedaliero Universitaria di Sassari", 
          "id": "https://www.grid.ac/institutes/grid.488385.a", 
          "name": [
            "Azienda Ospedaliero-Universitaria Di Sassari, Clinica Medica, Viale San Pietro 8, 07100, Sassari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Delitala", 
        "givenName": "Alessandro P.", 
        "id": "sg:person.0716750073.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716750073.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Sassari", 
          "id": "https://www.grid.ac/institutes/grid.11450.31", 
          "name": [
            "Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100, Sassari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Capobianco", 
        "givenName": "Giampiero", 
        "id": "sg:person.01121746550.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121746550.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Sassari", 
          "id": "https://www.grid.ac/institutes/grid.11450.31", 
          "name": [
            "Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100, Sassari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cherchi", 
        "givenName": "Pier Luigi", 
        "id": "sg:person.0623156350.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623156350.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Sassari", 
          "id": "https://www.grid.ac/institutes/grid.11450.31", 
          "name": [
            "Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100, Sassari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dessole", 
        "givenName": "Salvatore", 
        "id": "sg:person.01053313322.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053313322.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Sassari", 
          "id": "https://www.grid.ac/institutes/grid.11450.31", 
          "name": [
            "Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100, Sassari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Delitala", 
        "givenName": "Giuseppe", 
        "id": "sg:person.01371224222.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371224222.07"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00404-016-4219-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002033421", 
          "https://doi.org/10.1007/s00404-016-4219-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00404-016-4219-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002033421", 
          "https://doi.org/10.1007/s00404-016-4219-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000358873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002231875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.beem.2009.08.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002690790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcte.2016.11.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003162619"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humupd/dmr024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003748177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3121/cmr.2007.738", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003945542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.d2616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004099917"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199908193410801", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004241626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/cen.12177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004297666"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1651-2227.2000.tb18424.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004411697"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.1977.tb03322.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005031734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2011.0087", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005681694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.2009.03729.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006513878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.2009.03729.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006513878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijdevneu.2010.06.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007751133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1701-2163(16)34682-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008197895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000362597", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008831876"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/grf.0b013e3182272f32", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009806336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/grf.0b013e3182272f32", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009806336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/grf.0b013e3182272f32", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009806336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.292.6.691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010373240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12020-013-0086-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010662217", 
          "https://doi.org/10.1007/s12020-013-0086-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/mcn.12040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011015412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.maturitas.2016.07.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011825942"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijgo.2009.08.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012001614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1701-2163(16)34345-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017291879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1373/clinchem.2014.236646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017651777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/jpem.2009.22.6.547", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018647342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2826.2008.01733.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019052482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/1753-0407.12137", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019572493"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.1991.tb03494.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020825923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ecl.2011.08.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021428789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-16-0548", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021809814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejim.2016.12.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022355472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.numecd.2015.09.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022592395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fendo.2016.00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023976058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000441-199203000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024325250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000441-199203000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024325250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2265.2003.01822.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025070523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.physiol.62.1.439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025614132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-14-0182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025923762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ecl.2011.08.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026978501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00404-015-3741-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027962171", 
          "https://doi.org/10.1007/s00404-015-3741-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3182125b0c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028879003", 
          "https://doi.org/10.1203/pdr.0b013e3182125b0c"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/pdr.0b013e3182125b0c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028879003", 
          "https://doi.org/10.1203/pdr.0b013e3182125b0c"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/cen.13301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029209270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4158/ep09233.ra", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030871157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aog.0000197991.64246.9a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031477941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aog.0000197991.64246.9a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031477941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/cen.12532", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033251555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00404-011-2040-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033888631", 
          "https://doi.org/10.1007/s00404-011-2040-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2016.0457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037092811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4158/ep10309.ra", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037594234"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2012-2540", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039605912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2011-2803", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039863950"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/erc-11-0028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039883007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/erc-11-0028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039883007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/erc-11-0028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039883007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200102153440707", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041095379"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aog.0000262054.03531.24", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042983558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.aog.0000262054.03531.24", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042983558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.beem.2009.08.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043683537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1368980007360886", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043684286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1368980007360886", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043684286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2265.1999.00639.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043768896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03350244", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043839221", 
          "https://doi.org/10.1007/bf03350244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(08)61005-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043851063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1368980007360928", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043994065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1368980007360928", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043994065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2016.0014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044316959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s2213-8587(15)00327-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044817791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.1004123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045083003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jad.2015.11.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045651083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s2213-8587(15)00263-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046210233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ogx.0000000000000367", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047527875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ogx.0000000000000367", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047527875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198103193041205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047698165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.1984.tb00119.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048567607"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2015-3559", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048665060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00404-014-3533-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048888743", 
          "https://doi.org/10.1007/s00404-014-3533-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.2009.03743.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049806680"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.2009.03743.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049806680"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-0528.2004.00213.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052896565"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5812/ijem.19378", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053121415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0035-1564131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057347956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2005.15.777", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059319608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2007.0108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059320041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2008.0364", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059320423"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2011.0053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2012.0440", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2013.0215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2014.0007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321855"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2014.0029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321858"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2014.0548", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2015.0182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059322053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/edrv-15-6-788", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064238094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/edrv.18.3.0300", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064238403"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/en.2004-0274", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064246745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/er.2002-0030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064285764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/er.2009-0041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064285983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2003-031028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064287111"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2004-0571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064287814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2006-1748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064289529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2007-0141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064289851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2008-0936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064290728"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2010-0415", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064292080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2011-1772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064292989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2011-2038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064293044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2011-2860", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064293221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2012-2420", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064293723"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2013-1674", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064294301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2013-2855", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064294542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2013-4281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064294882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2015-2553", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064295903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.82.9.3099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064299815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem-43-6-1351", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064309515"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.75.5.1430095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064317838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.77.3.8370679", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064318300"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.82.9.4210", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064321257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.87.4.8434", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064325145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078024129", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078551620", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2017/4601365", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083821480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.psyneuen.2017.03.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084104336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/08830185.2016.1277216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084161467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1871530317666170320105221", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084504876"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0175708", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084870637"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/03007995.2017.1330259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085465875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00404-017-4429-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086119977", 
          "https://doi.org/10.1007/s00404-017-4429-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00404-017-4429-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086119977", 
          "https://doi.org/10.1007/s00404-017-4429-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2017-00846", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090160440"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrendo.2017.93", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090992540", 
          "https://doi.org/10.1038/nrendo.2017.93"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/ec-17-0076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091089301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0043-117893", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091807658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2017-01850", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092563029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-17-0628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1093074788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-17-0628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1093074788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-17-0628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1093074788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2017-01560", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099795535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/jir.2017.0059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099865346"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2017-01247", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100801117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40842-018-0054-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101279352", 
          "https://doi.org/10.1186/s40842-018-0054-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40842-018-0054-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101279352", 
          "https://doi.org/10.1186/s40842-018-0054-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40842-018-0054-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101279352", 
          "https://doi.org/10.1186/s40842-018-0054-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cyto.2018.08.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106431086"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cyto.2018.08.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106431086"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-02", 
    "datePublishedReg": "2019-02-01", 
    "description": "PURPOSE: To review the literature on thyroid function and thyroid disorders during pregnancy.\nMETHODS: A detailed literature research on MEDLINE, Cochrane library, EMBASE, NLH, ClinicalTrials.gov, and Google Scholar databases was done up to January 2018 with restriction to English language\u00a0about articles regarding thyroid diseases and pregnancy.\nRESULTS: Thyroid hormone deficiencies are known to be detrimental for the development of the fetus. In particular, the function of the central nervous system might be impaired, causing low intelligence quotient, and mental retardation. Overt and subclinical dysfunctions of the thyroid disease should be treated appropriately in pregnancy, aiming to maintain euthyroidism. Thyroxine (T4) replacement therapy should reduce thyrotropin (TSH) concentration to the recently suggested fixed upper limits of 2.5\u00a0mU/l (first and second trimester) and 3.0\u00a0mU/l (third trimester). Overt hyperthyroidism during pregnancy is relatively uncommon but needs prompt treatment due to the increased risk of preterm delivery, congenital malformations, and fetal death. The use of antithyroid drug (methimazole, propylthiouracil, carbimazole) is the first choice for treating overt hyperthyroidism, although they are not free of side effects. Subclinical hyperthyroidism tends to be asymptomatic and no pharmacological treatment is usually needed. Gestational transient hyperthyroidism is a self-limited non-autoimmune form of hyperthyroidism with negative antibody against TSH receptors, that is related to hCG-induced thyroid hormone secretion. The vast majority of these patients does not require antithyroid therapy, although administration of low doses of \u03b2-blocker may by useful in very symptomatic patients.\nCONCLUSIONS: Normal maternal thyroid function is essential in pregnancy to avoid adverse maternal and fetal outcomes.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00404-018-5018-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1017365", 
        "issn": [
          "0932-0067", 
          "1432-0711"
        ], 
        "name": "Archives of Gynecology and Obstetrics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "299"
      }
    ], 
    "name": "Thyroid function and thyroid disorders during pregnancy: a review and care pathway", 
    "pagination": "327-338", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d9a349b20b39e8646e479a0bdcfd8726060fb5e084992406859f99549dbabfa8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30569344"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8710213"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00404-018-5018-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1110764151"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00404-018-5018-8", 
      "https://app.dimensions.ai/details/publication/pub.1110764151"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:12", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000338_0000000338/records_47985_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00404-018-5018-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00404-018-5018-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00404-018-5018-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00404-018-5018-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00404-018-5018-8'


 

This table displays all metadata directly associated to this object as RDF triples.

489 TRIPLES      21 PREDICATES      156 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00404-018-5018-8 schema:about anzsrc-for:11
2 anzsrc-for:1114
3 schema:author N67b1b459eb6d4d6dba75b9600cdfb15c
4 schema:citation sg:pub.10.1007/bf03350244
5 sg:pub.10.1007/s00404-011-2040-5
6 sg:pub.10.1007/s00404-014-3533-9
7 sg:pub.10.1007/s00404-015-3741-y
8 sg:pub.10.1007/s00404-016-4219-2
9 sg:pub.10.1007/s00404-017-4429-2
10 sg:pub.10.1007/s12020-013-0086-9
11 sg:pub.10.1038/nrendo.2017.93
12 sg:pub.10.1186/s40842-018-0054-7
13 sg:pub.10.1203/pdr.0b013e3182125b0c
14 https://app.dimensions.ai/details/publication/pub.1078024129
15 https://app.dimensions.ai/details/publication/pub.1078551620
16 https://doi.org/10.1001/jama.292.6.691
17 https://doi.org/10.1016/j.beem.2009.08.007
18 https://doi.org/10.1016/j.beem.2009.08.014
19 https://doi.org/10.1016/j.cyto.2018.08.027
20 https://doi.org/10.1016/j.ecl.2011.08.001
21 https://doi.org/10.1016/j.ecl.2011.08.004
22 https://doi.org/10.1016/j.ejim.2016.12.015
23 https://doi.org/10.1016/j.ijdevneu.2010.06.007
24 https://doi.org/10.1016/j.ijgo.2009.08.006
25 https://doi.org/10.1016/j.jad.2015.11.019
26 https://doi.org/10.1016/j.jcte.2016.11.001
27 https://doi.org/10.1016/j.maturitas.2016.07.003
28 https://doi.org/10.1016/j.numecd.2015.09.001
29 https://doi.org/10.1016/j.psyneuen.2017.03.021
30 https://doi.org/10.1016/s0140-6736(08)61005-3
31 https://doi.org/10.1016/s1701-2163(16)34345-6
32 https://doi.org/10.1016/s1701-2163(16)34682-5
33 https://doi.org/10.1016/s2213-8587(15)00263-6
34 https://doi.org/10.1016/s2213-8587(15)00327-7
35 https://doi.org/10.1017/s1368980007360886
36 https://doi.org/10.1017/s1368980007360928
37 https://doi.org/10.1046/j.1365-2265.1999.00639.x
38 https://doi.org/10.1046/j.1365-2265.2003.01822.x
39 https://doi.org/10.1055/s-0035-1564131
40 https://doi.org/10.1055/s-0043-117893
41 https://doi.org/10.1056/nejm198103193041205
42 https://doi.org/10.1056/nejm199908193410801
43 https://doi.org/10.1056/nejm200102153440707
44 https://doi.org/10.1080/03007995.2017.1330259
45 https://doi.org/10.1080/08830185.2016.1277216
46 https://doi.org/10.1089/jir.2017.0059
47 https://doi.org/10.1089/thy.2005.15.777
48 https://doi.org/10.1089/thy.2007.0108
49 https://doi.org/10.1089/thy.2008.0364
50 https://doi.org/10.1089/thy.2011.0053
51 https://doi.org/10.1089/thy.2011.0087
52 https://doi.org/10.1089/thy.2012.0440
53 https://doi.org/10.1089/thy.2013.0215
54 https://doi.org/10.1089/thy.2014.0007
55 https://doi.org/10.1089/thy.2014.0029
56 https://doi.org/10.1089/thy.2014.0548
57 https://doi.org/10.1089/thy.2015.0182
58 https://doi.org/10.1089/thy.2016.0014
59 https://doi.org/10.1089/thy.2016.0457
60 https://doi.org/10.1093/humupd/dmr024
61 https://doi.org/10.1097/00000441-199203000-00011
62 https://doi.org/10.1097/01.aog.0000197991.64246.9a
63 https://doi.org/10.1097/01.aog.0000262054.03531.24
64 https://doi.org/10.1097/grf.0b013e3182272f32
65 https://doi.org/10.1097/ogx.0000000000000367
66 https://doi.org/10.1111/1753-0407.12137
67 https://doi.org/10.1111/cen.12177
68 https://doi.org/10.1111/cen.12532
69 https://doi.org/10.1111/cen.13301
70 https://doi.org/10.1111/j.1365-2265.1977.tb03322.x
71 https://doi.org/10.1111/j.1365-2265.1984.tb00119.x
72 https://doi.org/10.1111/j.1365-2265.1991.tb03494.x
73 https://doi.org/10.1111/j.1365-2265.2009.03729.x
74 https://doi.org/10.1111/j.1365-2265.2009.03743.x
75 https://doi.org/10.1111/j.1365-2826.2008.01733.x
76 https://doi.org/10.1111/j.1471-0528.2004.00213.x
77 https://doi.org/10.1111/j.1651-2227.2000.tb18424.x
78 https://doi.org/10.1111/mcn.12040
79 https://doi.org/10.1136/bmj.d2616
80 https://doi.org/10.1146/annurev.physiol.62.1.439
81 https://doi.org/10.1155/2017/4601365
82 https://doi.org/10.1159/000358873
83 https://doi.org/10.1159/000362597
84 https://doi.org/10.1210/edrv-15-6-788
85 https://doi.org/10.1210/edrv.18.3.0300
86 https://doi.org/10.1210/en.2004-0274
87 https://doi.org/10.1210/er.2002-0030
88 https://doi.org/10.1210/er.2009-0041
89 https://doi.org/10.1210/jc.2003-031028
90 https://doi.org/10.1210/jc.2004-0571
91 https://doi.org/10.1210/jc.2006-1748
92 https://doi.org/10.1210/jc.2007-0141
93 https://doi.org/10.1210/jc.2008-0936
94 https://doi.org/10.1210/jc.2010-0415
95 https://doi.org/10.1210/jc.2011-1772
96 https://doi.org/10.1210/jc.2011-2038
97 https://doi.org/10.1210/jc.2011-2803
98 https://doi.org/10.1210/jc.2011-2860
99 https://doi.org/10.1210/jc.2012-2420
100 https://doi.org/10.1210/jc.2012-2540
101 https://doi.org/10.1210/jc.2013-1674
102 https://doi.org/10.1210/jc.2013-2855
103 https://doi.org/10.1210/jc.2013-4281
104 https://doi.org/10.1210/jc.2015-2553
105 https://doi.org/10.1210/jc.2015-3559
106 https://doi.org/10.1210/jc.2017-00846
107 https://doi.org/10.1210/jc.2017-01247
108 https://doi.org/10.1210/jc.2017-01560
109 https://doi.org/10.1210/jc.2017-01850
110 https://doi.org/10.1210/jc.82.9.3099
111 https://doi.org/10.1210/jcem-43-6-1351
112 https://doi.org/10.1210/jcem.75.5.1430095
113 https://doi.org/10.1210/jcem.77.3.8370679
114 https://doi.org/10.1210/jcem.82.9.4210
115 https://doi.org/10.1210/jcem.87.4.8434
116 https://doi.org/10.1371/journal.pgen.1004123
117 https://doi.org/10.1371/journal.pone.0175708
118 https://doi.org/10.1373/clinchem.2014.236646
119 https://doi.org/10.1515/jpem.2009.22.6.547
120 https://doi.org/10.1530/ec-17-0076
121 https://doi.org/10.1530/eje-14-0182
122 https://doi.org/10.1530/eje-16-0548
123 https://doi.org/10.1530/eje-17-0628
124 https://doi.org/10.1530/erc-11-0028
125 https://doi.org/10.2174/1871530317666170320105221
126 https://doi.org/10.3121/cmr.2007.738
127 https://doi.org/10.3389/fendo.2016.00016
128 https://doi.org/10.4158/ep09233.ra
129 https://doi.org/10.4158/ep10309.ra
130 https://doi.org/10.5812/ijem.19378
131 schema:datePublished 2019-02
132 schema:datePublishedReg 2019-02-01
133 schema:description PURPOSE: To review the literature on thyroid function and thyroid disorders during pregnancy. METHODS: A detailed literature research on MEDLINE, Cochrane library, EMBASE, NLH, ClinicalTrials.gov, and Google Scholar databases was done up to January 2018 with restriction to English language about articles regarding thyroid diseases and pregnancy. RESULTS: Thyroid hormone deficiencies are known to be detrimental for the development of the fetus. In particular, the function of the central nervous system might be impaired, causing low intelligence quotient, and mental retardation. Overt and subclinical dysfunctions of the thyroid disease should be treated appropriately in pregnancy, aiming to maintain euthyroidism. Thyroxine (T4) replacement therapy should reduce thyrotropin (TSH) concentration to the recently suggested fixed upper limits of 2.5 mU/l (first and second trimester) and 3.0 mU/l (third trimester). Overt hyperthyroidism during pregnancy is relatively uncommon but needs prompt treatment due to the increased risk of preterm delivery, congenital malformations, and fetal death. The use of antithyroid drug (methimazole, propylthiouracil, carbimazole) is the first choice for treating overt hyperthyroidism, although they are not free of side effects. Subclinical hyperthyroidism tends to be asymptomatic and no pharmacological treatment is usually needed. Gestational transient hyperthyroidism is a self-limited non-autoimmune form of hyperthyroidism with negative antibody against TSH receptors, that is related to hCG-induced thyroid hormone secretion. The vast majority of these patients does not require antithyroid therapy, although administration of low doses of β-blocker may by useful in very symptomatic patients. CONCLUSIONS: Normal maternal thyroid function is essential in pregnancy to avoid adverse maternal and fetal outcomes.
134 schema:genre research_article
135 schema:inLanguage en
136 schema:isAccessibleForFree false
137 schema:isPartOf N35c3b55feda14a78a84b739cb8026eb6
138 Nc3869fa933844f56aabe33db66290399
139 sg:journal.1017365
140 schema:name Thyroid function and thyroid disorders during pregnancy: a review and care pathway
141 schema:pagination 327-338
142 schema:productId N3c49e8daa09546998c8bec854d466971
143 N5cb2413488744a149c0f3a27daf9c017
144 N6761a56e5fc442cb827c2ca656505b81
145 N6895e6fd004649fe88aee3cc7f215150
146 Ne352415db49741a7811f4f3419cf09c5
147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110764151
148 https://doi.org/10.1007/s00404-018-5018-8
149 schema:sdDatePublished 2019-04-11T09:12
150 schema:sdLicense https://scigraph.springernature.com/explorer/license/
151 schema:sdPublisher N7dd643f2543e471f80dc82d64e62b2af
152 schema:url https://link.springer.com/10.1007%2Fs00404-018-5018-8
153 sgo:license sg:explorer/license/
154 sgo:sdDataset articles
155 rdf:type schema:ScholarlyArticle
156 N0832a8e035904397a2ed9334ea975a4f rdf:first sg:person.0623156350.97
157 rdf:rest N2a9cd7e7ea5c45f3b3b0673fb2f71580
158 N092de34e89b447a495b55041e4cbeac8 rdf:first sg:person.01121746550.58
159 rdf:rest N0832a8e035904397a2ed9334ea975a4f
160 N2a9cd7e7ea5c45f3b3b0673fb2f71580 rdf:first sg:person.01053313322.90
161 rdf:rest Ne147fbb911c441d08666874d7162eb35
162 N35c3b55feda14a78a84b739cb8026eb6 schema:volumeNumber 299
163 rdf:type schema:PublicationVolume
164 N3c49e8daa09546998c8bec854d466971 schema:name readcube_id
165 schema:value d9a349b20b39e8646e479a0bdcfd8726060fb5e084992406859f99549dbabfa8
166 rdf:type schema:PropertyValue
167 N5cb2413488744a149c0f3a27daf9c017 schema:name dimensions_id
168 schema:value pub.1110764151
169 rdf:type schema:PropertyValue
170 N6761a56e5fc442cb827c2ca656505b81 schema:name nlm_unique_id
171 schema:value 8710213
172 rdf:type schema:PropertyValue
173 N67b1b459eb6d4d6dba75b9600cdfb15c rdf:first sg:person.0716750073.17
174 rdf:rest N092de34e89b447a495b55041e4cbeac8
175 N6895e6fd004649fe88aee3cc7f215150 schema:name doi
176 schema:value 10.1007/s00404-018-5018-8
177 rdf:type schema:PropertyValue
178 N7dd643f2543e471f80dc82d64e62b2af schema:name Springer Nature - SN SciGraph project
179 rdf:type schema:Organization
180 Nc3869fa933844f56aabe33db66290399 schema:issueNumber 2
181 rdf:type schema:PublicationIssue
182 Ne147fbb911c441d08666874d7162eb35 rdf:first sg:person.01371224222.07
183 rdf:rest rdf:nil
184 Ne352415db49741a7811f4f3419cf09c5 schema:name pubmed_id
185 schema:value 30569344
186 rdf:type schema:PropertyValue
187 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
188 schema:name Medical and Health Sciences
189 rdf:type schema:DefinedTerm
190 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
191 schema:name Paediatrics and Reproductive Medicine
192 rdf:type schema:DefinedTerm
193 sg:journal.1017365 schema:issn 0932-0067
194 1432-0711
195 schema:name Archives of Gynecology and Obstetrics
196 rdf:type schema:Periodical
197 sg:person.01053313322.90 schema:affiliation https://www.grid.ac/institutes/grid.11450.31
198 schema:familyName Dessole
199 schema:givenName Salvatore
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053313322.90
201 rdf:type schema:Person
202 sg:person.01121746550.58 schema:affiliation https://www.grid.ac/institutes/grid.11450.31
203 schema:familyName Capobianco
204 schema:givenName Giampiero
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121746550.58
206 rdf:type schema:Person
207 sg:person.01371224222.07 schema:affiliation https://www.grid.ac/institutes/grid.11450.31
208 schema:familyName Delitala
209 schema:givenName Giuseppe
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371224222.07
211 rdf:type schema:Person
212 sg:person.0623156350.97 schema:affiliation https://www.grid.ac/institutes/grid.11450.31
213 schema:familyName Cherchi
214 schema:givenName Pier Luigi
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623156350.97
216 rdf:type schema:Person
217 sg:person.0716750073.17 schema:affiliation https://www.grid.ac/institutes/grid.488385.a
218 schema:familyName Delitala
219 schema:givenName Alessandro P.
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716750073.17
221 rdf:type schema:Person
222 sg:pub.10.1007/bf03350244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043839221
223 https://doi.org/10.1007/bf03350244
224 rdf:type schema:CreativeWork
225 sg:pub.10.1007/s00404-011-2040-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033888631
226 https://doi.org/10.1007/s00404-011-2040-5
227 rdf:type schema:CreativeWork
228 sg:pub.10.1007/s00404-014-3533-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048888743
229 https://doi.org/10.1007/s00404-014-3533-9
230 rdf:type schema:CreativeWork
231 sg:pub.10.1007/s00404-015-3741-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1027962171
232 https://doi.org/10.1007/s00404-015-3741-y
233 rdf:type schema:CreativeWork
234 sg:pub.10.1007/s00404-016-4219-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002033421
235 https://doi.org/10.1007/s00404-016-4219-2
236 rdf:type schema:CreativeWork
237 sg:pub.10.1007/s00404-017-4429-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086119977
238 https://doi.org/10.1007/s00404-017-4429-2
239 rdf:type schema:CreativeWork
240 sg:pub.10.1007/s12020-013-0086-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010662217
241 https://doi.org/10.1007/s12020-013-0086-9
242 rdf:type schema:CreativeWork
243 sg:pub.10.1038/nrendo.2017.93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090992540
244 https://doi.org/10.1038/nrendo.2017.93
245 rdf:type schema:CreativeWork
246 sg:pub.10.1186/s40842-018-0054-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101279352
247 https://doi.org/10.1186/s40842-018-0054-7
248 rdf:type schema:CreativeWork
249 sg:pub.10.1203/pdr.0b013e3182125b0c schema:sameAs https://app.dimensions.ai/details/publication/pub.1028879003
250 https://doi.org/10.1203/pdr.0b013e3182125b0c
251 rdf:type schema:CreativeWork
252 https://app.dimensions.ai/details/publication/pub.1078024129 schema:CreativeWork
253 https://app.dimensions.ai/details/publication/pub.1078551620 schema:CreativeWork
254 https://doi.org/10.1001/jama.292.6.691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010373240
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1016/j.beem.2009.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043683537
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1016/j.beem.2009.08.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002690790
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1016/j.cyto.2018.08.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106431086
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1016/j.ecl.2011.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021428789
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1016/j.ecl.2011.08.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026978501
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1016/j.ejim.2016.12.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022355472
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1016/j.ijdevneu.2010.06.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007751133
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1016/j.ijgo.2009.08.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012001614
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1016/j.jad.2015.11.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045651083
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1016/j.jcte.2016.11.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003162619
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1016/j.maturitas.2016.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011825942
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1016/j.numecd.2015.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022592395
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1016/j.psyneuen.2017.03.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084104336
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1016/s0140-6736(08)61005-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043851063
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1016/s1701-2163(16)34345-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017291879
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/s1701-2163(16)34682-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008197895
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/s2213-8587(15)00263-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046210233
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1016/s2213-8587(15)00327-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044817791
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1017/s1368980007360886 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043684286
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1017/s1368980007360928 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043994065
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1046/j.1365-2265.1999.00639.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043768896
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1046/j.1365-2265.2003.01822.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025070523
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1055/s-0035-1564131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057347956
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1055/s-0043-117893 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091807658
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1056/nejm198103193041205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047698165
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1056/nejm199908193410801 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004241626
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1056/nejm200102153440707 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041095379
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1080/03007995.2017.1330259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085465875
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1080/08830185.2016.1277216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084161467
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1089/jir.2017.0059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099865346
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1089/thy.2005.15.777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059319608
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1089/thy.2007.0108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059320041
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1089/thy.2008.0364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059320423
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1089/thy.2011.0053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321139
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1089/thy.2011.0087 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005681694
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1089/thy.2012.0440 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321535
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1089/thy.2013.0215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321726
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1089/thy.2014.0007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321855
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1089/thy.2014.0029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321858
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1089/thy.2014.0548 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321971
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1089/thy.2015.0182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059322053
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1089/thy.2016.0014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044316959
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1089/thy.2016.0457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037092811
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1093/humupd/dmr024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003748177
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1097/00000441-199203000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024325250
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1097/01.aog.0000197991.64246.9a schema:sameAs https://app.dimensions.ai/details/publication/pub.1031477941
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1097/01.aog.0000262054.03531.24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042983558
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1097/grf.0b013e3182272f32 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009806336
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1097/ogx.0000000000000367 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047527875
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1111/1753-0407.12137 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019572493
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1111/cen.12177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004297666
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1111/cen.12532 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033251555
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1111/cen.13301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029209270
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1111/j.1365-2265.1977.tb03322.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005031734
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1111/j.1365-2265.1984.tb00119.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048567607
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1111/j.1365-2265.1991.tb03494.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020825923
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1111/j.1365-2265.2009.03729.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006513878
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1111/j.1365-2265.2009.03743.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049806680
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1111/j.1365-2826.2008.01733.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019052482
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1111/j.1471-0528.2004.00213.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1052896565
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1111/j.1651-2227.2000.tb18424.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004411697
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1111/mcn.12040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011015412
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1136/bmj.d2616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004099917
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1146/annurev.physiol.62.1.439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025614132
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1155/2017/4601365 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083821480
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1159/000358873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002231875
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1159/000362597 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008831876
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1210/edrv-15-6-788 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064238094
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1210/edrv.18.3.0300 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064238403
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1210/en.2004-0274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064246745
395 rdf:type schema:CreativeWork
396 https://doi.org/10.1210/er.2002-0030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064285764
397 rdf:type schema:CreativeWork
398 https://doi.org/10.1210/er.2009-0041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064285983
399 rdf:type schema:CreativeWork
400 https://doi.org/10.1210/jc.2003-031028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287111
401 rdf:type schema:CreativeWork
402 https://doi.org/10.1210/jc.2004-0571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287814
403 rdf:type schema:CreativeWork
404 https://doi.org/10.1210/jc.2006-1748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064289529
405 rdf:type schema:CreativeWork
406 https://doi.org/10.1210/jc.2007-0141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064289851
407 rdf:type schema:CreativeWork
408 https://doi.org/10.1210/jc.2008-0936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290728
409 rdf:type schema:CreativeWork
410 https://doi.org/10.1210/jc.2010-0415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064292080
411 rdf:type schema:CreativeWork
412 https://doi.org/10.1210/jc.2011-1772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064292989
413 rdf:type schema:CreativeWork
414 https://doi.org/10.1210/jc.2011-2038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064293044
415 rdf:type schema:CreativeWork
416 https://doi.org/10.1210/jc.2011-2803 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039863950
417 rdf:type schema:CreativeWork
418 https://doi.org/10.1210/jc.2011-2860 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064293221
419 rdf:type schema:CreativeWork
420 https://doi.org/10.1210/jc.2012-2420 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064293723
421 rdf:type schema:CreativeWork
422 https://doi.org/10.1210/jc.2012-2540 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039605912
423 rdf:type schema:CreativeWork
424 https://doi.org/10.1210/jc.2013-1674 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064294301
425 rdf:type schema:CreativeWork
426 https://doi.org/10.1210/jc.2013-2855 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064294542
427 rdf:type schema:CreativeWork
428 https://doi.org/10.1210/jc.2013-4281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064294882
429 rdf:type schema:CreativeWork
430 https://doi.org/10.1210/jc.2015-2553 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064295903
431 rdf:type schema:CreativeWork
432 https://doi.org/10.1210/jc.2015-3559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048665060
433 rdf:type schema:CreativeWork
434 https://doi.org/10.1210/jc.2017-00846 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090160440
435 rdf:type schema:CreativeWork
436 https://doi.org/10.1210/jc.2017-01247 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100801117
437 rdf:type schema:CreativeWork
438 https://doi.org/10.1210/jc.2017-01560 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099795535
439 rdf:type schema:CreativeWork
440 https://doi.org/10.1210/jc.2017-01850 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092563029
441 rdf:type schema:CreativeWork
442 https://doi.org/10.1210/jc.82.9.3099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064299815
443 rdf:type schema:CreativeWork
444 https://doi.org/10.1210/jcem-43-6-1351 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064309515
445 rdf:type schema:CreativeWork
446 https://doi.org/10.1210/jcem.75.5.1430095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064317838
447 rdf:type schema:CreativeWork
448 https://doi.org/10.1210/jcem.77.3.8370679 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064318300
449 rdf:type schema:CreativeWork
450 https://doi.org/10.1210/jcem.82.9.4210 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064321257
451 rdf:type schema:CreativeWork
452 https://doi.org/10.1210/jcem.87.4.8434 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064325145
453 rdf:type schema:CreativeWork
454 https://doi.org/10.1371/journal.pgen.1004123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045083003
455 rdf:type schema:CreativeWork
456 https://doi.org/10.1371/journal.pone.0175708 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084870637
457 rdf:type schema:CreativeWork
458 https://doi.org/10.1373/clinchem.2014.236646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017651777
459 rdf:type schema:CreativeWork
460 https://doi.org/10.1515/jpem.2009.22.6.547 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018647342
461 rdf:type schema:CreativeWork
462 https://doi.org/10.1530/ec-17-0076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091089301
463 rdf:type schema:CreativeWork
464 https://doi.org/10.1530/eje-14-0182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025923762
465 rdf:type schema:CreativeWork
466 https://doi.org/10.1530/eje-16-0548 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021809814
467 rdf:type schema:CreativeWork
468 https://doi.org/10.1530/eje-17-0628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1093074788
469 rdf:type schema:CreativeWork
470 https://doi.org/10.1530/erc-11-0028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039883007
471 rdf:type schema:CreativeWork
472 https://doi.org/10.2174/1871530317666170320105221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084504876
473 rdf:type schema:CreativeWork
474 https://doi.org/10.3121/cmr.2007.738 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003945542
475 rdf:type schema:CreativeWork
476 https://doi.org/10.3389/fendo.2016.00016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023976058
477 rdf:type schema:CreativeWork
478 https://doi.org/10.4158/ep09233.ra schema:sameAs https://app.dimensions.ai/details/publication/pub.1030871157
479 rdf:type schema:CreativeWork
480 https://doi.org/10.4158/ep10309.ra schema:sameAs https://app.dimensions.ai/details/publication/pub.1037594234
481 rdf:type schema:CreativeWork
482 https://doi.org/10.5812/ijem.19378 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053121415
483 rdf:type schema:CreativeWork
484 https://www.grid.ac/institutes/grid.11450.31 schema:alternateName University of Sassari
485 schema:name Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100, Sassari, Italy
486 rdf:type schema:Organization
487 https://www.grid.ac/institutes/grid.488385.a schema:alternateName Azienda Ospedaliero Universitaria di Sassari
488 schema:name Azienda Ospedaliero-Universitaria Di Sassari, Clinica Medica, Viale San Pietro 8, 07100, Sassari, Italy
489 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...