Comparison of three treatment strategies for cesarean scar pregnancy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-06-20

AUTHORS

Guangquan Liu, Jiacong Wu, Jian Cao, Yunping Xue, Chencheng Dai, Juan Xu, Xuemei Jia

ABSTRACT

PurposeTo explore the optimal treatment for cesarean scar pregnancy.MethodIn total, 86 women diagnosed with a cesarean scar pregnancy were divided into three groups according to treatment. The human chorionic gonadotrophin (hCG) decline percentage, intraoperative blood loss and success rate were analyzed in Group A [combination of uterine arterial embolization (UAE), local methotrexate (MTX) injection and dilation & curettage (D&C)], Group B (combination of UAE and local MTX injection) and Group C (D&C). Then, the best treatment was carefully analyzed, and recommendations were provided.ResultsThe success rate was highest in Group A (97.5%) compared with Group B (76%) and Group C (63.15%). The reduction in hCG was greatest in Group A (86.62%, 44.0–99.97%) compared with group B (67.83%, 18.0–98.03%) and Group C (68.21%, 27.0–93.24%). The intraoperative blood loss was lowest in Group A (44.881, 5–200 ml) compared with Group C (224.737, 10–1000 ml). Additionally, we found that the best time to perform D&C in group A depended on the hCG reduction percentage, and a 35% reduction after UAE and local MTX injection could be used as the indicator to perform D&C.ConclusionsThe combination of UAE, local MTX injection and D&C for CSP patients is the optimal treatment strategy. A 35% reduction in hCG after UAE and local MTX injection can be recommended as the indicator to perform D&C. More... »

PAGES

383-389

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00404-017-4426-5

DOI

http://dx.doi.org/10.1007/s00404-017-4426-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1086099145

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28634752


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