Ontology type: schema:ScholarlyArticle
2021-01-12
AUTHORSAdam G. Evans, Mirjana G. Ivanic, Mina A. Botros, Rand W. Pope, Briana R. Halle, Gabriella E. Glassman, Rafaella Genova, Salam Al Kassis
ABSTRACTIntradermal injection of autologous platelet-rich plasma (PRP) is a non-surgical cosmetic therapy to rejuvenate the periorbital area pathologies of wrinkles, periorbital hyperpigmentation (POH), and photoaging. The past decade has seen the adoption of this novel therapy around the world. This is the first systematic review and meta-analysis evaluating PRP treatment of periorbital pathologies. This is a PRISMA compliant review that includes a comprehensive search of the databases Cochrane Library, Ovid Medline, Ovid Embase, and clinicaltrials.gov. The search was performed in June 2019 to obtain all peer-reviewed articles published in English that describe the application of PRP to periorbital pathologies. A meta-analysis of patient satisfaction was performed for randomized controlled trials. Nineteen studies treating 455 patients (95% female, age range 28–60) were included. Studies were categorized based on reported outcomes: wrinkles (11 studies), POH (7 studies), and photoaging (6 studies). Patients were treated a mean of 3 times (range 1–8) in mean intervals of 23 days (range 14–56 days). Follow-up averaged 3 months (range 1–6 months). Meta-analysis of 3 randomized controlled clinical trials (RCTs) shows that patients treated with PRP have increased satisfaction above controls of saline, platelet-poor plasma, mesotherapy, and as an adjunct to laser therapy (overall effect p = 0.001, heterogeneity I2 = 64%). PRP treatment of periorbital area pathologies results in histologic improvements of photoaging, subjective satisfaction score increases, and blind evaluator assessments of rejuvenated skin appearance. Future studies are needed to address limitations of the current literature and should include long-term follow-up, delineation of the POH etiology that is treated, RCTs with low risk of bias, and be absent conflicts of interest or industry sponsors.Trial registration: Prospero Systematic Review Registration ID: CRD42019135968 More... »
PAGES711-727
http://scigraph.springernature.com/pub.10.1007/s00403-020-02173-z
DOIhttp://dx.doi.org/10.1007/s00403-020-02173-z
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1134505309
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/33433716
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Blood Transfusion, Autologous",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cosmetic Techniques",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Face",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Injections, Intradermal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Patient Satisfaction",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Platelet-Rich Plasma",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Randomized Controlled Trials as Topic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Rejuvenation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Skin Aging",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Treatment Outcome",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, 660 S. Euclid Ave, 63110, St. Louis, MO, USA",
"id": "http://www.grid.ac/institutes/grid.4367.6",
"name": [
"Meharry Medical College, 1005 Dr DB Todd Jr Blvd, 37208, Nashville, TN, USA",
"Division of Plastic and Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, 660 S. Euclid Ave, 63110, St. Louis, MO, USA"
],
"type": "Organization"
},
"familyName": "Evans",
"givenName": "Adam G.",
"id": "sg:person.014061400117.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014061400117.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Plastic Surgery, Vanderbilt University Medical Center, D-4207 Medical Center North, 1211 Medical Center Drive, 37212, Nashville, TN, USA",
"id": "http://www.grid.ac/institutes/grid.412807.8",
"name": [
"Meharry Medical College, 1005 Dr DB Todd Jr Blvd, 37208, Nashville, TN, USA",
"Department of Plastic Surgery, Vanderbilt University Medical Center, D-4207 Medical Center North, 1211 Medical Center Drive, 37212, Nashville, TN, USA"
],
"type": "Organization"
},
"familyName": "Ivanic",
"givenName": "Mirjana G.",
"id": "sg:person.014525777575.92",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014525777575.92"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Meharry Medical College, 1005 Dr DB Todd Jr Blvd, 37208, Nashville, TN, USA",
"id": "http://www.grid.ac/institutes/grid.259870.1",
"name": [
"Meharry Medical College, 1005 Dr DB Todd Jr Blvd, 37208, Nashville, TN, USA"
],
"type": "Organization"
},
"familyName": "Botros",
"givenName": "Mina A.",
"id": "sg:person.015335334113.30",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015335334113.30"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Vanderbilt University School of Medicine, 1161 21st Ave South, 37232, Nashville, TN, USA",
"id": "http://www.grid.ac/institutes/grid.152326.1",
"name": [
"Vanderbilt University School of Medicine, 1161 21st Ave South, 37232, Nashville, TN, USA"
],
"type": "Organization"
},
"familyName": "Pope",
"givenName": "Rand W.",
"id": "sg:person.015454341117.20",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015454341117.20"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Vanderbilt University School of Medicine, 1161 21st Ave South, 37232, Nashville, TN, USA",
"id": "http://www.grid.ac/institutes/grid.152326.1",
"name": [
"Vanderbilt University School of Medicine, 1161 21st Ave South, 37232, Nashville, TN, USA"
],
"type": "Organization"
},
"familyName": "Halle",
"givenName": "Briana R.",
"id": "sg:person.013505227077.01",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013505227077.01"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Plastic Surgery, Vanderbilt University Medical Center, D-4207 Medical Center North, 1211 Medical Center Drive, 37212, Nashville, TN, USA",
"id": "http://www.grid.ac/institutes/grid.412807.8",
"name": [
"Department of Plastic Surgery, Vanderbilt University Medical Center, D-4207 Medical Center North, 1211 Medical Center Drive, 37212, Nashville, TN, USA"
],
"type": "Organization"
},
"familyName": "Glassman",
"givenName": "Gabriella E.",
"id": "sg:person.011010630375.22",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011010630375.22"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Tennessee Health Science Center, 910 Madison Ave, 38163, Memphis, TN, USA",
"id": "http://www.grid.ac/institutes/grid.267301.1",
"name": [
"University of Tennessee Health Science Center, 910 Madison Ave, 38163, Memphis, TN, USA"
],
"type": "Organization"
},
"familyName": "Genova",
"givenName": "Rafaella",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Plastic Surgery, Vanderbilt University Medical Center, D-4207 Medical Center North, 1211 Medical Center Drive, 37212, Nashville, TN, USA",
"id": "http://www.grid.ac/institutes/grid.412807.8",
"name": [
"Department of Plastic Surgery, Vanderbilt University Medical Center, D-4207 Medical Center North, 1211 Medical Center Drive, 37212, Nashville, TN, USA"
],
"type": "Organization"
},
"familyName": "Al Kassis",
"givenName": "Salam",
"id": "sg:person.01054023366.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054023366.35"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s00403-010-1086-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022694257",
"https://doi.org/10.1007/s00403-010-1086-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s40634-019-0190-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1116558349",
"https://doi.org/10.1186/s40634-019-0190-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1684/ejd.2014.2267",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078870803",
"https://doi.org/10.1684/ejd.2014.2267"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00266-012-9963-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047105741",
"https://doi.org/10.1007/s00266-012-9963-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00784-019-02981-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1118099161",
"https://doi.org/10.1007/s00784-019-02981-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00266-014-0361-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033343904",
"https://doi.org/10.1007/s00266-014-0361-z"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrrheum.2013.141",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012054256",
"https://doi.org/10.1038/nrrheum.2013.141"
],
"type": "CreativeWork"
}
],
"datePublished": "2021-01-12",
"datePublishedReg": "2021-01-12",
"description": "Intradermal injection of autologous platelet-rich plasma (PRP) is a non-surgical cosmetic therapy to rejuvenate the periorbital area pathologies of wrinkles, periorbital hyperpigmentation (POH), and photoaging. The past decade has seen the adoption of this novel therapy around the world. This is the first systematic review and meta-analysis evaluating PRP treatment of periorbital pathologies. This is a PRISMA compliant review that includes a comprehensive search of the databases Cochrane Library, Ovid Medline, Ovid Embase, and clinicaltrials.gov. The search was performed in June 2019 to obtain all peer-reviewed articles published in English that describe the application of PRP to periorbital pathologies. A meta-analysis of patient satisfaction was performed for randomized controlled trials. Nineteen studies treating 455 patients (95% female, age range 28\u201360) were included. Studies were categorized based on reported outcomes: wrinkles (11 studies), POH (7 studies), and photoaging (6 studies). Patients were treated a mean of 3 times (range 1\u20138) in mean intervals of 23\u00a0days (range 14\u201356\u00a0days). Follow-up averaged 3\u00a0months (range 1\u20136\u00a0months). Meta-analysis of 3 randomized controlled clinical trials (RCTs) shows that patients treated with PRP have increased satisfaction above controls of saline, platelet-poor plasma, mesotherapy, and as an adjunct to laser therapy (overall effect p\u2009=\u20090.001, heterogeneity I2\u2009=\u200964%). PRP treatment of periorbital area pathologies results in histologic improvements of photoaging, subjective satisfaction score increases, and blind evaluator assessments of rejuvenated skin appearance. Future studies are needed to address limitations of the current literature and should include long-term follow-up, delineation of the POH etiology that is treated, RCTs with low risk of bias, and be absent conflicts of interest or industry sponsors.Trial registration: Prospero Systematic Review Registration ID: CRD42019135968",
"genre": "article",
"id": "sg:pub.10.1007/s00403-020-02173-z",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1054393",
"issn": [
"0340-3696",
"1432-069X"
],
"name": "Archives of Dermatological Research",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "9",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "313"
}
],
"keywords": [
"platelet-rich plasma",
"periorbital hyperpigmentation",
"PRP treatment",
"systematic review",
"autologous platelet-rich plasma",
"application of PRP",
"databases Cochrane Library",
"platelet-poor plasma",
"controls of saline",
"PRISMA-compliant review",
"periorbital pathology",
"first systematic review",
"histologic improvement",
"Ovid Embase",
"Cochrane Library",
"patient satisfaction",
"clinical trials",
"intradermal injection",
"mean interval",
"registration ID",
"novel therapies",
"Ovid MEDLINE",
"laser therapy",
"Nineteen studies",
"lower risk",
"periorbital area",
"comprehensive search",
"patients",
"cosmetic therapy",
"therapy",
"pathology",
"skin appearance",
"score increase",
"photoaging",
"peer-reviewed articles",
"current literature",
"trials",
"future studies",
"treatment",
"review",
"evaluators' assessments",
"EMBASE",
"RCTs",
"MEDLINE",
"industry sponsors",
"mesotherapy",
"etiology",
"hyperpigmentation",
"adjunct",
"plasma",
"months",
"saline",
"study",
"outcomes",
"injection",
"risk",
"satisfaction",
"days",
"past decade",
"search",
"interval",
"assessment",
"control",
"wrinkles",
"appearance",
"increase",
"delineation",
"improvement",
"rejuvenating",
"literature",
"bias",
"time",
"sponsors",
"decades",
"area",
"limitations",
"ID",
"means",
"English",
"library",
"article",
"interest",
"world",
"adoption",
"applications",
"conflict"
],
"name": "Rejuvenating the periorbital area using platelet-rich plasma: a systematic review and meta-analysis",
"pagination": "711-727",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1134505309"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00403-020-02173-z"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"33433716"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00403-020-02173-z",
"https://app.dimensions.ai/details/publication/pub.1134505309"
],
"sdDataset": "articles",
"sdDatePublished": "2022-08-04T17:09",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_877.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s00403-020-02173-z"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00403-020-02173-z'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00403-020-02173-z'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00403-020-02173-z'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00403-020-02173-z'
This table displays all metadata directly associated to this object as RDF triples.
281 TRIPLES
21 PREDICATES
128 URIs
113 LITERALS
18 BLANK NODES