Lectin-like transcript 1 (LLT1) expression is associated with nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma. View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-06

AUTHORS

J Santos-Juanes, I Fernández-Vega, S Lorenzo-Herrero, C Sordo-Bahamonde, P Martínez-Camblor, J M García-Pedrero, B Vivanco, C Galache-Osuna, F Vazquez-Lopez, S Gonzalez, J P Rodrigo

ABSTRACT

The interaction of lectin-like transcript 1 (LLT1) with CD161 inhibits Natural Killer cell activation. Overexpression of LLT1 contributes to the immunosuppressive properties of tumor cells. However, there are little data about LLT1 expression in human solid tumors. The objective of this paper is to investigate the relationship between LLT1 expression with the clinicopathologic features and its impact on the prognosis of head and neck cutaneous squamous cell carcinoma (cSCC). LLT1 expression was analyzed on paraffin-embedded tissue samples obtained from 100 patients with cSCC by immunohistochemistry. The estimator of Fine and Gray was used to estimate the cumulative incidence curves for relapse. Proportional Hazard models and Hazard ratios (HRs) were used for studying the risk of tumor relapse and mortality. LLT1 strong expression was a significant risk factor for nodal metastasis with crude and adjusted ratios (HRs) of 3.40 (95% CI 1.39-9.28) and 3.25 (95% CI 1.15-9.16); and for cSCC specific death of 6.17 (95% CI 1.79-21.2) and 6.10 (95% CI 1.45-25.7). Strong LLT1 expression is an independent predictor of nodal metastasis and poor disease-specific survival and it might be helpful for risk stratification of patients with cSCC. More... »

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00403-019-01916-x

DOI

http://dx.doi.org/10.1007/s00403-019-01916-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113283315

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30955082


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Service of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain. jorgesantosjuanes@gmail.com.", 
            "Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain. jorgesantosjuanes@gmail.com.", 
            "Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain. jorgesantosjuanes@gmail.com."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Santos-Juanes", 
        "givenName": "J", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Service of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain.", 
            "Departamento de Cirug\u00eda y especialidades M\u00e9dico-quir\u00fargicas, Universidad de Oviedo, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fern\u00e1ndez-Vega", 
        "givenName": "I", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain.", 
            "Instituto Universitario de Oncolog\u00eda del Principado de Asturias, Oviedo, Spain.", 
            "Department of Functional Biology, University of Oviedo, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lorenzo-Herrero", 
        "givenName": "S", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain.", 
            "Instituto Universitario de Oncolog\u00eda del Principado de Asturias, Oviedo, Spain.", 
            "Department of Functional Biology, University of Oviedo, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sordo-Bahamonde", 
        "givenName": "C", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dartmouth College", 
          "id": "https://www.grid.ac/institutes/grid.254880.3", 
          "name": [
            "Geisel School of Medicine at Dartmouth, Dartmouth College, Hannover, NH, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mart\u00ednez-Camblor", 
        "givenName": "P", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain.", 
            "Instituto Universitario de Oncolog\u00eda del Principado de Asturias, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Garc\u00eda-Pedrero", 
        "givenName": "J M", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Service of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain.", 
            "Departamento de Cirug\u00eda y especialidades M\u00e9dico-quir\u00fargicas, Universidad de Oviedo, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vivanco", 
        "givenName": "B", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University Hospital of Asturias", 
          "id": "https://www.grid.ac/institutes/grid.411052.3", 
          "name": [
            "Service of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Galache-Osuna", 
        "givenName": "C", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Service of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain.", 
            "Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vazquez-Lopez", 
        "givenName": "F", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain.", 
            "Instituto Universitario de Oncolog\u00eda del Principado de Asturias, Oviedo, Spain.", 
            "Department of Functional Biology, University of Oviedo, Oviedo, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonzalez", 
        "givenName": "S", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oviedo", 
          "id": "https://www.grid.ac/institutes/grid.10863.3c", 
          "name": [
            "Instituto de Investigaci\u00f3n Sanitaria del Principado de Asturias, Oviedo, Spain.", 
            "Instituto Universitario de Oncolog\u00eda del Principado de Asturias, Oviedo, Spain.", 
            "Department of Otolaryngology, Hospital Universitario Central de Asturias and Oviedo, Oviedo, Spain.", 
            "CIBERONC, Madrid, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodrigo", 
        "givenName": "J P", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1371/journal.pone.0132436", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004132063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002510050679", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005546453", 
          "https://doi.org/10.1007/s002510050679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaad.2012.11.037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007134382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.11896", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009064153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1214/aos/1176350951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010369076"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-06-4783", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020229224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.175.12.7791", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028483203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.0804281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032832600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/jid.2013.304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033518397", 
          "https://doi.org/10.1038/jid.2013.304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(07)61602-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036200026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2012.48.5326", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036760003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.02789-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039927118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2133.2011.10507.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040938537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.imlet.2016.07.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042439626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.2012.63", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047335023", 
          "https://doi.org/10.1038/modpathol.2012.63"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(08)70178-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052800553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01621459.1999.10474144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058305593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.12688/f1000research.10009.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064611896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.175.12.7796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077154008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078970351", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.1502462", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079220285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083324920", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaad.2017.01.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084083529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaad.2017.01.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084083529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jid.2017.06.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090834787"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04-06", 
    "datePublishedReg": "2019-04-06", 
    "description": "The interaction of lectin-like transcript 1 (LLT1) with CD161 inhibits Natural Killer cell activation. Overexpression of LLT1 contributes to the immunosuppressive properties of tumor cells. However, there are little data about LLT1 expression in human solid tumors. The objective of this paper is to investigate the relationship between LLT1 expression with the clinicopathologic features and its impact on the prognosis of head and neck cutaneous squamous cell carcinoma (cSCC). LLT1 expression was analyzed on paraffin-embedded tissue samples obtained from 100 patients with cSCC by immunohistochemistry. The estimator of Fine and Gray was used to estimate the cumulative incidence curves for relapse. Proportional Hazard models and Hazard ratios (HRs) were used for studying the risk of tumor relapse and mortality. LLT1 strong expression was a significant risk factor for nodal metastasis with crude and adjusted ratios (HRs) of 3.40 (95% CI 1.39-9.28) and 3.25 (95% CI 1.15-9.16); and for cSCC specific death of 6.17 (95% CI 1.79-21.2) and 6.10 (95% CI 1.45-25.7). Strong LLT1 expression is an independent predictor of nodal metastasis and poor disease-specific survival and it might be helpful for risk stratification of patients with cSCC.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00403-019-01916-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1054393", 
        "issn": [
          "0340-3696", 
          "1432-069X"
        ], 
        "name": "Archives of Dermatological Research", 
        "type": "Periodical"
      }
    ], 
    "name": "Lectin-like transcript 1 (LLT1) expression is associated with nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma.", 
    "productId": [
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30955082"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8000462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00403-019-01916-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113283315"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00403-019-01916-x", 
      "https://app.dimensions.ai/details/publication/pub.1113283315"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:30", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13087_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00403-019-01916-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00403-019-01916-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00403-019-01916-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00403-019-01916-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00403-019-01916-x'


 

This table displays all metadata directly associated to this object as RDF triples.

207 TRIPLES      20 PREDICATES      48 URIs      16 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00403-019-01916-x schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author N198e1e9ee65a4239995a540affdc503b
4 schema:citation sg:pub.10.1007/s002510050679
5 sg:pub.10.1038/jid.2013.304
6 sg:pub.10.1038/modpathol.2012.63
7 https://app.dimensions.ai/details/publication/pub.1078970351
8 https://app.dimensions.ai/details/publication/pub.1083324920
9 https://doi.org/10.1016/j.imlet.2016.07.007
10 https://doi.org/10.1016/j.jaad.2012.11.037
11 https://doi.org/10.1016/j.jaad.2017.01.015
12 https://doi.org/10.1016/j.jid.2017.06.025
13 https://doi.org/10.1016/s0140-6736(07)61602-x
14 https://doi.org/10.1016/s1470-2045(08)70178-5
15 https://doi.org/10.1080/01621459.1999.10474144
16 https://doi.org/10.1111/j.1365-2133.2011.10507.x
17 https://doi.org/10.1128/jvi.02789-13
18 https://doi.org/10.1158/0008-5472.can-06-4783
19 https://doi.org/10.1200/jco.2012.48.5326
20 https://doi.org/10.1214/aos/1176350951
21 https://doi.org/10.12688/f1000research.10009.1
22 https://doi.org/10.1371/journal.pone.0132436
23 https://doi.org/10.18632/oncotarget.11896
24 https://doi.org/10.4049/jimmunol.0804281
25 https://doi.org/10.4049/jimmunol.1502462
26 https://doi.org/10.4049/jimmunol.175.12.7791
27 https://doi.org/10.4049/jimmunol.175.12.7796
28 schema:datePublished 2019-04-06
29 schema:datePublishedReg 2019-04-06
30 schema:description The interaction of lectin-like transcript 1 (LLT1) with CD161 inhibits Natural Killer cell activation. Overexpression of LLT1 contributes to the immunosuppressive properties of tumor cells. However, there are little data about LLT1 expression in human solid tumors. The objective of this paper is to investigate the relationship between LLT1 expression with the clinicopathologic features and its impact on the prognosis of head and neck cutaneous squamous cell carcinoma (cSCC). LLT1 expression was analyzed on paraffin-embedded tissue samples obtained from 100 patients with cSCC by immunohistochemistry. The estimator of Fine and Gray was used to estimate the cumulative incidence curves for relapse. Proportional Hazard models and Hazard ratios (HRs) were used for studying the risk of tumor relapse and mortality. LLT1 strong expression was a significant risk factor for nodal metastasis with crude and adjusted ratios (HRs) of 3.40 (95% CI 1.39-9.28) and 3.25 (95% CI 1.15-9.16); and for cSCC specific death of 6.17 (95% CI 1.79-21.2) and 6.10 (95% CI 1.45-25.7). Strong LLT1 expression is an independent predictor of nodal metastasis and poor disease-specific survival and it might be helpful for risk stratification of patients with cSCC.
31 schema:genre research_article
32 schema:inLanguage en
33 schema:isAccessibleForFree false
34 schema:isPartOf sg:journal.1054393
35 schema:name Lectin-like transcript 1 (LLT1) expression is associated with nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma.
36 schema:productId N4ca9891e896542e4b68b691ac471c86d
37 N6daad95fb3304cb8a22fee9617147b47
38 Nb98d510ed4294bff887229d959be529a
39 Nc4ced2777c124fcda09852182e44600e
40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113283315
41 https://doi.org/10.1007/s00403-019-01916-x
42 schema:sdDatePublished 2019-04-11T14:30
43 schema:sdLicense https://scigraph.springernature.com/explorer/license/
44 schema:sdPublisher Nb94b79031f654d33882ac2d3b812b749
45 schema:url http://link.springer.com/10.1007/s00403-019-01916-x
46 sgo:license sg:explorer/license/
47 sgo:sdDataset articles
48 rdf:type schema:ScholarlyArticle
49 N06e5fdf0429e444f84740f4a582884d3 schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
50 schema:familyName Fernández-Vega
51 schema:givenName I
52 rdf:type schema:Person
53 N191e1c5a998345bb84071bd0a18198f5 schema:affiliation https://www.grid.ac/institutes/grid.411052.3
54 schema:familyName Galache-Osuna
55 schema:givenName C
56 rdf:type schema:Person
57 N198e1e9ee65a4239995a540affdc503b rdf:first N51fa545ac27f43c891b535d543f7ef68
58 rdf:rest N7b4bbe7d2d35447e9ce8a9ee9fbf242b
59 N2ddd9f29c63c49f8bf797841807e9d5a rdf:first N6dddb4053d6149329da4f09a99577e9e
60 rdf:rest N837957d0cd54454cbb2c1445c20d8905
61 N344fc284014a4b408a6d87707b5d7084 schema:affiliation https://www.grid.ac/institutes/grid.254880.3
62 schema:familyName Martínez-Camblor
63 schema:givenName P
64 rdf:type schema:Person
65 N4ca9891e896542e4b68b691ac471c86d schema:name dimensions_id
66 schema:value pub.1113283315
67 rdf:type schema:PropertyValue
68 N4ccc05d95f4543fab5b2dbb57075de09 rdf:first Na645760636194413a66c0294b317d2bc
69 rdf:rest Nede90d50e98d4bd2816494cd75f1ec1b
70 N51fa545ac27f43c891b535d543f7ef68 schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
71 schema:familyName Santos-Juanes
72 schema:givenName J
73 rdf:type schema:Person
74 N6a97bbcc25d34434877f188af5cb1294 rdf:first Nbcabddb6fe854582b473bc82a4b77646
75 rdf:rest N2ddd9f29c63c49f8bf797841807e9d5a
76 N6daad95fb3304cb8a22fee9617147b47 schema:name pubmed_id
77 schema:value 30955082
78 rdf:type schema:PropertyValue
79 N6dddb4053d6149329da4f09a99577e9e schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
80 schema:familyName Gonzalez
81 schema:givenName S
82 rdf:type schema:Person
83 N72e9ecc659f44439b5f774e167a33f5c rdf:first Nfe2014e1f4fe46aea4eb6c18d7d90535
84 rdf:rest N82beb76c10b04787871412682f3193ef
85 N7b4bbe7d2d35447e9ce8a9ee9fbf242b rdf:first N06e5fdf0429e444f84740f4a582884d3
86 rdf:rest N72e9ecc659f44439b5f774e167a33f5c
87 N7b6bfdb3a5db42c48f717e7c9f7b9aa9 rdf:first N191e1c5a998345bb84071bd0a18198f5
88 rdf:rest N6a97bbcc25d34434877f188af5cb1294
89 N811a0e4eca534b0db4c7e90fd8ee8d2a schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
90 schema:familyName Rodrigo
91 schema:givenName J P
92 rdf:type schema:Person
93 N82beb76c10b04787871412682f3193ef rdf:first Nc357a91abd7647e0a9fd90bf22a74be6
94 rdf:rest N8e4be498b69b41f7b7b106b739e657bb
95 N837957d0cd54454cbb2c1445c20d8905 rdf:first N811a0e4eca534b0db4c7e90fd8ee8d2a
96 rdf:rest rdf:nil
97 N8e4be498b69b41f7b7b106b739e657bb rdf:first N344fc284014a4b408a6d87707b5d7084
98 rdf:rest N4ccc05d95f4543fab5b2dbb57075de09
99 Na645760636194413a66c0294b317d2bc schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
100 schema:familyName García-Pedrero
101 schema:givenName J M
102 rdf:type schema:Person
103 Nb94b79031f654d33882ac2d3b812b749 schema:name Springer Nature - SN SciGraph project
104 rdf:type schema:Organization
105 Nb98d510ed4294bff887229d959be529a schema:name nlm_unique_id
106 schema:value 8000462
107 rdf:type schema:PropertyValue
108 Nbcabddb6fe854582b473bc82a4b77646 schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
109 schema:familyName Vazquez-Lopez
110 schema:givenName F
111 rdf:type schema:Person
112 Nc357a91abd7647e0a9fd90bf22a74be6 schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
113 schema:familyName Sordo-Bahamonde
114 schema:givenName C
115 rdf:type schema:Person
116 Nc4ced2777c124fcda09852182e44600e schema:name doi
117 schema:value 10.1007/s00403-019-01916-x
118 rdf:type schema:PropertyValue
119 Nede90d50e98d4bd2816494cd75f1ec1b rdf:first Nfee3a84304ea4769a4146a2fbe4182e2
120 rdf:rest N7b6bfdb3a5db42c48f717e7c9f7b9aa9
121 Nfe2014e1f4fe46aea4eb6c18d7d90535 schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
122 schema:familyName Lorenzo-Herrero
123 schema:givenName S
124 rdf:type schema:Person
125 Nfee3a84304ea4769a4146a2fbe4182e2 schema:affiliation https://www.grid.ac/institutes/grid.10863.3c
126 schema:familyName Vivanco
127 schema:givenName B
128 rdf:type schema:Person
129 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
130 schema:name Medical and Health Sciences
131 rdf:type schema:DefinedTerm
132 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
133 schema:name Oncology and Carcinogenesis
134 rdf:type schema:DefinedTerm
135 sg:journal.1054393 schema:issn 0340-3696
136 1432-069X
137 schema:name Archives of Dermatological Research
138 rdf:type schema:Periodical
139 sg:pub.10.1007/s002510050679 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005546453
140 https://doi.org/10.1007/s002510050679
141 rdf:type schema:CreativeWork
142 sg:pub.10.1038/jid.2013.304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033518397
143 https://doi.org/10.1038/jid.2013.304
144 rdf:type schema:CreativeWork
145 sg:pub.10.1038/modpathol.2012.63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047335023
146 https://doi.org/10.1038/modpathol.2012.63
147 rdf:type schema:CreativeWork
148 https://app.dimensions.ai/details/publication/pub.1078970351 schema:CreativeWork
149 https://app.dimensions.ai/details/publication/pub.1083324920 schema:CreativeWork
150 https://doi.org/10.1016/j.imlet.2016.07.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042439626
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1016/j.jaad.2012.11.037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007134382
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1016/j.jaad.2017.01.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084083529
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1016/j.jid.2017.06.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090834787
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1016/s0140-6736(07)61602-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036200026
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1016/s1470-2045(08)70178-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052800553
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1080/01621459.1999.10474144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058305593
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1111/j.1365-2133.2011.10507.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040938537
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1128/jvi.02789-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039927118
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1158/0008-5472.can-06-4783 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020229224
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1200/jco.2012.48.5326 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036760003
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1214/aos/1176350951 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010369076
173 rdf:type schema:CreativeWork
174 https://doi.org/10.12688/f1000research.10009.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064611896
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1371/journal.pone.0132436 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004132063
177 rdf:type schema:CreativeWork
178 https://doi.org/10.18632/oncotarget.11896 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009064153
179 rdf:type schema:CreativeWork
180 https://doi.org/10.4049/jimmunol.0804281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032832600
181 rdf:type schema:CreativeWork
182 https://doi.org/10.4049/jimmunol.1502462 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079220285
183 rdf:type schema:CreativeWork
184 https://doi.org/10.4049/jimmunol.175.12.7791 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028483203
185 rdf:type schema:CreativeWork
186 https://doi.org/10.4049/jimmunol.175.12.7796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077154008
187 rdf:type schema:CreativeWork
188 https://www.grid.ac/institutes/grid.10863.3c schema:alternateName University of Oviedo
189 schema:name CIBERONC, Madrid, Spain.
190 Departamento de Cirugía y especialidades Médico-quirúrgicas, Universidad de Oviedo, Oviedo, Spain.
191 Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain.
192 Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain. jorgesantosjuanes@gmail.com.
193 Department of Functional Biology, University of Oviedo, Oviedo, Spain.
194 Department of Otolaryngology, Hospital Universitario Central de Asturias and Oviedo, Oviedo, Spain.
195 Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain.
196 Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.
197 Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain. jorgesantosjuanes@gmail.com.
198 Service of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain.
199 Service of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain. jorgesantosjuanes@gmail.com.
200 Service of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain.
201 rdf:type schema:Organization
202 https://www.grid.ac/institutes/grid.254880.3 schema:alternateName Dartmouth College
203 schema:name Geisel School of Medicine at Dartmouth, Dartmouth College, Hannover, NH, USA.
204 rdf:type schema:Organization
205 https://www.grid.ac/institutes/grid.411052.3 schema:alternateName Central University Hospital of Asturias
206 schema:name Service of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain.
207 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...