Design and preliminary biomechanical analysis of a novel motion preservation device for lumbar spinal disease after vertebral corpectomy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02-12

AUTHORS

Jiantao Liu, Xijing He, Zhengchao Gao, Binbin Niu, Dongbo Lv, Yanzheng Gao

ABSTRACT

OBJECTIVE: To design a novel prosthesis, a movable artificial lumbar complex (MALC), for non-fusion reconstruction after lumbar subtotal corpectomy and to evaluate the stability, range of motion and load-bearing strength in the human cadaveric lumbar spine. METHODS: Biomechanical tests were performed on lumbar spine specimens from 15 healthy cadavers which were divided in three groups: non-fusion, fusion and intact group. The range of motion (ROM), stability and load-bearing strength were measured. RESULTS: The prosthesis was composed of three parts: the upper and lower artificial lumbar discs and the middle artificial vertebra. Both the MALC and titanium mesh cage re-established vertebral height, and no spinal cord compression or prosthesis dislocation was observed at the operative level. Regarding stability, there was no significant difference in all directions between the intact group and non-fusion group (P > 0.05). Segment movements of the specimens in the non-fusion group revealed significantly decreased T12-L1 ROM and significantly increased L1-2 and L2-3 ROM in flexion/extension and lateral bending compared with those in the fusion group (P < 0.05). Regarding load-bearing strength, when the lumbar vertebra was ruptured, there was no damage to the MALC and titanium mesh cage, but the maximum load in the non-fusion group was larger (P > 0.05). CONCLUSIONS: Compared with titanium cages, the MALC prosthesis not only restored the vertebral height and effectively preserved segment movements without any abnormal gain of mobility in adjacent inter-vertebral spaces but also bore the lumbar load and reduced the local stress load of adjacent vertebral endplates. More... »

PAGES

1-10

References to SciGraph publications

  • 2017-11. Lumbar subtotal corpectomy non-fusion model produced using a novel prosthesis in ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • 2015-09. An 11-year minimum follow-up of the Charite III lumbar disc replacement for the treatment of symptomatic degenerative disc disease in EUROPEAN SPINE JOURNAL
  • 2016-05. Adjacent segment degeneration after lumbar spinal fusion compared with motion-preservation procedures: a meta-analysis in EUROPEAN SPINE JOURNAL
  • 2015-04. The influence of intrinsic disc degeneration of the adjacent segments on its stress distribution after one-level lumbar fusion in EUROPEAN SPINE JOURNAL
  • 1998-05. Testing criteria for spinal implants: recommendations for the standardization of in vitro stability testing of spinal implants in EUROPEAN SPINE JOURNAL
  • 2008-05. En bloc spondylectomy reconstructions in a biomechanical in-vitro study in EUROPEAN SPINE JOURNAL
  • 2013-09. Erratum to: Design and preliminary biomechanical analysis of artificial cervical joint complex in ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • 2004-07. Expandierbare Cages als Wirbelkörperersatz in DER CHIRURG
  • 2007-06. Vertebral body replacement system Synex in unstable burst fractures of the thoracic and lumbar spine in JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
  • 2011-09. Biomechanical comparison of the end plate design of three vertebral body replacement systems in ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • 2017-09. Anterior monosegmental stabilization and fusion of an incomplete cranial burst fracture in the thoracolumbar spine via a mini-open, thoracoscopically assisted transthoracic approach in EUROPEAN SPINE JOURNAL
  • 2018-12. Prospective randomized controlled comparison of posterior vs. posterior–anterior stabilization of thoracolumbar incomplete cranial burst fractures in neurological intact patients: the RASPUTHINE pilot study in EUROPEAN SPINE JOURNAL
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00402-018-03106-2

    DOI

    http://dx.doi.org/10.1007/s00402-018-03106-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112073889

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30747259


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Henan Provincial People's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.414011.1", 
              "name": [
                "Department of Spine and Spinal Cord, Henan Provincial People\u2019s Hospital, No.7, the Weft Fifth Road, Jinshui District, Zhengzhou, Henan, People\u2019s Republic of China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Liu", 
            "givenName": "Jiantao", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Affiliated Hospital of Xi'an Jiaotong University", 
              "id": "https://www.grid.ac/institutes/grid.452672.0", 
              "name": [
                "Department of Orthopedics, Second Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, Shaanxi, People\u2019s Republic of China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "He", 
            "givenName": "Xijing", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Affiliated Hospital of Xi'an Jiaotong University", 
              "id": "https://www.grid.ac/institutes/grid.452672.0", 
              "name": [
                "Department of Orthopedics, Second Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, Shaanxi, People\u2019s Republic of China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gao", 
            "givenName": "Zhengchao", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Affiliated Hospital of Xi'an Jiaotong University", 
              "id": "https://www.grid.ac/institutes/grid.452672.0", 
              "name": [
                "Department of Orthopedics, Second Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, Shaanxi, People\u2019s Republic of China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Niu", 
            "givenName": "Binbin", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Henan Provincial People's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.414011.1", 
              "name": [
                "Department of Spine and Spinal Cord, Henan Provincial People\u2019s Hospital, No.7, the Weft Fifth Road, Jinshui District, Zhengzhou, Henan, People\u2019s Republic of China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lv", 
            "givenName": "Dongbo", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Henan Provincial People's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.414011.1", 
              "name": [
                "Department of Spine and Spinal Cord, Henan Provincial People\u2019s Hospital, No.7, the Weft Fifth Road, Jinshui District, Zhengzhou, Henan, People\u2019s Republic of China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gao", 
            "givenName": "Yanzheng", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s00586-014-3462-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002998799", 
              "https://doi.org/10.1007/s00586-014-3462-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10195-007-0166-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003962217", 
              "https://doi.org/10.1007/s10195-007-0166-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10195-007-0166-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003962217", 
              "https://doi.org/10.1007/s10195-007-0166-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.arcmed.2010.08.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005906707"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jocn.2014.02.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008039209"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.6061/clinics/2015(07)06", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013330855"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-016-4415-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014190679", 
              "https://doi.org/10.1007/s00586-016-4415-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clinbiomech.2007.07.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015174176"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s005860050045", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018786418", 
              "https://doi.org/10.1007/s005860050045"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00104-003-0786-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021906927", 
              "https://doi.org/10.1007/s00104-003-0786-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/bsd.0000000000000328", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022327278"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/bsd.0000000000000328", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022327278"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.injury.2012.04.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025932607"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00007632-199710150-00009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028132890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00007632-199710150-00009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028132890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clineuro.2014.10.019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030431680"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0052910", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037345949"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.wneu.2014.12.039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040215245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-015-3939-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043367221", 
              "https://doi.org/10.1007/s00586-015-3939-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-015-3939-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043367221", 
              "https://doi.org/10.1007/s00586-015-3939-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00402-011-1284-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044983060", 
              "https://doi.org/10.1007/s00402-011-1284-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-008-0588-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045548550", 
              "https://doi.org/10.1007/s00586-008-0588-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-008-0588-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045548550", 
              "https://doi.org/10.1007/s00586-008-0588-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/bsd.0b013e3182867489", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047927275"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/bsd.0b013e3182867489", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047927275"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7759/cureus.637", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049132452"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00402-013-1826-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052757798", 
              "https://doi.org/10.1007/s00402-013-1826-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077724743", 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-017-5011-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084022725", 
              "https://doi.org/10.1007/s00586-017-5011-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-017-5011-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084022725", 
              "https://doi.org/10.1007/s00586-017-5011-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.12659/msm.905466", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085986831"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.12659/msm.901993", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086256335"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.spinee.2017.06.035", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090319519"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.wneu.2017.08.179", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091491843"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00402-017-2753-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091512228", 
              "https://doi.org/10.1007/s00402-017-2753-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00586-017-5356-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092347913", 
              "https://doi.org/10.1007/s00586-017-5356-4"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-02-12", 
        "datePublishedReg": "2019-02-12", 
        "description": "OBJECTIVE: To design a novel prosthesis, a movable artificial lumbar complex (MALC), for non-fusion reconstruction after lumbar subtotal corpectomy and to evaluate the stability, range of motion and load-bearing strength in the human cadaveric lumbar spine.\nMETHODS: Biomechanical tests were performed on lumbar spine specimens from 15 healthy cadavers which were divided in three groups: non-fusion, fusion and intact group. The range of motion (ROM), stability and load-bearing strength were measured.\nRESULTS: The prosthesis was composed of three parts: the upper and lower artificial lumbar discs and the middle artificial vertebra. Both the MALC and titanium mesh cage re-established vertebral height, and no spinal cord compression or prosthesis dislocation was observed at the operative level. Regarding stability, there was no significant difference in all directions between the intact group and non-fusion group (P\u2009>\u20090.05). Segment movements of the specimens in the non-fusion group revealed significantly decreased T12-L1 ROM and significantly increased L1-2 and L2-3 ROM in flexion/extension and lateral bending compared with those in the fusion group (P\u2009<\u20090.05). Regarding load-bearing strength, when the lumbar vertebra was ruptured, there was no damage to the MALC and titanium mesh cage, but the maximum load in the non-fusion group was larger (P\u2009>\u20090.05).\nCONCLUSIONS: Compared with titanium cages, the MALC prosthesis not only restored the vertebral height and effectively preserved segment movements without any abnormal gain of mobility in adjacent inter-vertebral spaces but also bore the lumbar load and reduced the local stress load of adjacent vertebral endplates.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s00402-018-03106-2", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1087582", 
            "issn": [
              "0936-8051", 
              "1434-3916"
            ], 
            "name": "Archives of Orthopaedic and Trauma Surgery", 
            "type": "Periodical"
          }
        ], 
        "name": "Design and preliminary biomechanical analysis of a novel motion preservation device for lumbar spinal disease after vertebral corpectomy", 
        "pagination": "1-10", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "814f006b435c35bd06d928c8a325ede1e3e1eb0623f30af0ef04a869b7f4e0be"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "30747259"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "9011043"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00402-018-03106-2"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1112073889"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00402-018-03106-2", 
          "https://app.dimensions.ai/details/publication/pub.1112073889"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T09:05", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000335_0000000335/records_125274_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1007%2Fs00402-018-03106-2"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00402-018-03106-2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00402-018-03106-2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00402-018-03106-2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00402-018-03106-2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    193 TRIPLES      21 PREDICATES      55 URIs      18 LITERALS      7 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00402-018-03106-2 schema:about anzsrc-for:11
    2 anzsrc-for:1103
    3 schema:author N2ae95f93b48049b9840f8dc68d64dfcb
    4 schema:citation sg:pub.10.1007/s00104-003-0786-4
    5 sg:pub.10.1007/s00402-011-1284-7
    6 sg:pub.10.1007/s00402-013-1826-2
    7 sg:pub.10.1007/s00402-017-2753-4
    8 sg:pub.10.1007/s00586-008-0588-y
    9 sg:pub.10.1007/s00586-014-3462-0
    10 sg:pub.10.1007/s00586-015-3939-5
    11 sg:pub.10.1007/s00586-016-4415-6
    12 sg:pub.10.1007/s00586-017-5011-0
    13 sg:pub.10.1007/s00586-017-5356-4
    14 sg:pub.10.1007/s005860050045
    15 sg:pub.10.1007/s10195-007-0166-9
    16 https://app.dimensions.ai/details/publication/pub.1077724743
    17 https://doi.org/10.1016/j.arcmed.2010.08.013
    18 https://doi.org/10.1016/j.clinbiomech.2007.07.010
    19 https://doi.org/10.1016/j.clineuro.2014.10.019
    20 https://doi.org/10.1016/j.injury.2012.04.008
    21 https://doi.org/10.1016/j.jocn.2014.02.016
    22 https://doi.org/10.1016/j.spinee.2017.06.035
    23 https://doi.org/10.1016/j.wneu.2014.12.039
    24 https://doi.org/10.1016/j.wneu.2017.08.179
    25 https://doi.org/10.1097/00007632-199710150-00009
    26 https://doi.org/10.1097/bsd.0000000000000328
    27 https://doi.org/10.1097/bsd.0b013e3182867489
    28 https://doi.org/10.12659/msm.901993
    29 https://doi.org/10.12659/msm.905466
    30 https://doi.org/10.1371/journal.pone.0052910
    31 https://doi.org/10.6061/clinics/2015(07)06
    32 https://doi.org/10.7759/cureus.637
    33 schema:datePublished 2019-02-12
    34 schema:datePublishedReg 2019-02-12
    35 schema:description OBJECTIVE: To design a novel prosthesis, a movable artificial lumbar complex (MALC), for non-fusion reconstruction after lumbar subtotal corpectomy and to evaluate the stability, range of motion and load-bearing strength in the human cadaveric lumbar spine. METHODS: Biomechanical tests were performed on lumbar spine specimens from 15 healthy cadavers which were divided in three groups: non-fusion, fusion and intact group. The range of motion (ROM), stability and load-bearing strength were measured. RESULTS: The prosthesis was composed of three parts: the upper and lower artificial lumbar discs and the middle artificial vertebra. Both the MALC and titanium mesh cage re-established vertebral height, and no spinal cord compression or prosthesis dislocation was observed at the operative level. Regarding stability, there was no significant difference in all directions between the intact group and non-fusion group (P > 0.05). Segment movements of the specimens in the non-fusion group revealed significantly decreased T12-L1 ROM and significantly increased L1-2 and L2-3 ROM in flexion/extension and lateral bending compared with those in the fusion group (P < 0.05). Regarding load-bearing strength, when the lumbar vertebra was ruptured, there was no damage to the MALC and titanium mesh cage, but the maximum load in the non-fusion group was larger (P > 0.05). CONCLUSIONS: Compared with titanium cages, the MALC prosthesis not only restored the vertebral height and effectively preserved segment movements without any abnormal gain of mobility in adjacent inter-vertebral spaces but also bore the lumbar load and reduced the local stress load of adjacent vertebral endplates.
    36 schema:genre research_article
    37 schema:inLanguage en
    38 schema:isAccessibleForFree false
    39 schema:isPartOf sg:journal.1087582
    40 schema:name Design and preliminary biomechanical analysis of a novel motion preservation device for lumbar spinal disease after vertebral corpectomy
    41 schema:pagination 1-10
    42 schema:productId N2fe6b47743764b18a85836f2c7f05037
    43 Na1d869da47434984a037d1728fc9178c
    44 Na5858400b19441198b07041929a6fc92
    45 Nb74777db0a664602903dde47e29c11ad
    46 Ne94c11e4f742416d9363eb141202ea73
    47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112073889
    48 https://doi.org/10.1007/s00402-018-03106-2
    49 schema:sdDatePublished 2019-04-11T09:05
    50 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    51 schema:sdPublisher Nb5ef9353eaff47b7bcfe4d3cf8d10b6c
    52 schema:url https://link.springer.com/10.1007%2Fs00402-018-03106-2
    53 sgo:license sg:explorer/license/
    54 sgo:sdDataset articles
    55 rdf:type schema:ScholarlyArticle
    56 N2ae95f93b48049b9840f8dc68d64dfcb rdf:first Nc38ea07d6c2344e5839cc8523358ace1
    57 rdf:rest N2ca1ed720e5d454e9e593f3af9c4dbc5
    58 N2ca1ed720e5d454e9e593f3af9c4dbc5 rdf:first N51578c08c431458a9b7958fda7e7e820
    59 rdf:rest Nd0cbb7c6e2a24e9e975f2d8d254720e5
    60 N2fe6b47743764b18a85836f2c7f05037 schema:name dimensions_id
    61 schema:value pub.1112073889
    62 rdf:type schema:PropertyValue
    63 N384177270fa5490ebe64c35dee648d44 schema:affiliation https://www.grid.ac/institutes/grid.414011.1
    64 schema:familyName Lv
    65 schema:givenName Dongbo
    66 rdf:type schema:Person
    67 N51578c08c431458a9b7958fda7e7e820 schema:affiliation https://www.grid.ac/institutes/grid.452672.0
    68 schema:familyName He
    69 schema:givenName Xijing
    70 rdf:type schema:Person
    71 N7328dde598fa448f926a2b95d26fd70c schema:affiliation https://www.grid.ac/institutes/grid.452672.0
    72 schema:familyName Gao
    73 schema:givenName Zhengchao
    74 rdf:type schema:Person
    75 N9a9b34668a2d436abc2d6d6a7e1ab186 rdf:first N384177270fa5490ebe64c35dee648d44
    76 rdf:rest Nc19bbc5f711a40098d07c60bacc531b6
    77 Na1d869da47434984a037d1728fc9178c schema:name readcube_id
    78 schema:value 814f006b435c35bd06d928c8a325ede1e3e1eb0623f30af0ef04a869b7f4e0be
    79 rdf:type schema:PropertyValue
    80 Na5858400b19441198b07041929a6fc92 schema:name pubmed_id
    81 schema:value 30747259
    82 rdf:type schema:PropertyValue
    83 Nb5ef9353eaff47b7bcfe4d3cf8d10b6c schema:name Springer Nature - SN SciGraph project
    84 rdf:type schema:Organization
    85 Nb74777db0a664602903dde47e29c11ad schema:name nlm_unique_id
    86 schema:value 9011043
    87 rdf:type schema:PropertyValue
    88 Nbda31131f51f4169842a1405be59834d schema:affiliation https://www.grid.ac/institutes/grid.414011.1
    89 schema:familyName Gao
    90 schema:givenName Yanzheng
    91 rdf:type schema:Person
    92 Nc19bbc5f711a40098d07c60bacc531b6 rdf:first Nbda31131f51f4169842a1405be59834d
    93 rdf:rest rdf:nil
    94 Nc38ea07d6c2344e5839cc8523358ace1 schema:affiliation https://www.grid.ac/institutes/grid.414011.1
    95 schema:familyName Liu
    96 schema:givenName Jiantao
    97 rdf:type schema:Person
    98 Nd0cbb7c6e2a24e9e975f2d8d254720e5 rdf:first N7328dde598fa448f926a2b95d26fd70c
    99 rdf:rest Ne2ff93e16e7d49db83e7de54ec65b0af
    100 Ne2ff93e16e7d49db83e7de54ec65b0af rdf:first Ne6bc539beffc4f70aaa672f99fcbf15b
    101 rdf:rest N9a9b34668a2d436abc2d6d6a7e1ab186
    102 Ne6bc539beffc4f70aaa672f99fcbf15b schema:affiliation https://www.grid.ac/institutes/grid.452672.0
    103 schema:familyName Niu
    104 schema:givenName Binbin
    105 rdf:type schema:Person
    106 Ne94c11e4f742416d9363eb141202ea73 schema:name doi
    107 schema:value 10.1007/s00402-018-03106-2
    108 rdf:type schema:PropertyValue
    109 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    110 schema:name Medical and Health Sciences
    111 rdf:type schema:DefinedTerm
    112 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    113 schema:name Clinical Sciences
    114 rdf:type schema:DefinedTerm
    115 sg:journal.1087582 schema:issn 0936-8051
    116 1434-3916
    117 schema:name Archives of Orthopaedic and Trauma Surgery
    118 rdf:type schema:Periodical
    119 sg:pub.10.1007/s00104-003-0786-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021906927
    120 https://doi.org/10.1007/s00104-003-0786-4
    121 rdf:type schema:CreativeWork
    122 sg:pub.10.1007/s00402-011-1284-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044983060
    123 https://doi.org/10.1007/s00402-011-1284-7
    124 rdf:type schema:CreativeWork
    125 sg:pub.10.1007/s00402-013-1826-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052757798
    126 https://doi.org/10.1007/s00402-013-1826-2
    127 rdf:type schema:CreativeWork
    128 sg:pub.10.1007/s00402-017-2753-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091512228
    129 https://doi.org/10.1007/s00402-017-2753-4
    130 rdf:type schema:CreativeWork
    131 sg:pub.10.1007/s00586-008-0588-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1045548550
    132 https://doi.org/10.1007/s00586-008-0588-y
    133 rdf:type schema:CreativeWork
    134 sg:pub.10.1007/s00586-014-3462-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002998799
    135 https://doi.org/10.1007/s00586-014-3462-0
    136 rdf:type schema:CreativeWork
    137 sg:pub.10.1007/s00586-015-3939-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043367221
    138 https://doi.org/10.1007/s00586-015-3939-5
    139 rdf:type schema:CreativeWork
    140 sg:pub.10.1007/s00586-016-4415-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014190679
    141 https://doi.org/10.1007/s00586-016-4415-6
    142 rdf:type schema:CreativeWork
    143 sg:pub.10.1007/s00586-017-5011-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084022725
    144 https://doi.org/10.1007/s00586-017-5011-0
    145 rdf:type schema:CreativeWork
    146 sg:pub.10.1007/s00586-017-5356-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092347913
    147 https://doi.org/10.1007/s00586-017-5356-4
    148 rdf:type schema:CreativeWork
    149 sg:pub.10.1007/s005860050045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018786418
    150 https://doi.org/10.1007/s005860050045
    151 rdf:type schema:CreativeWork
    152 sg:pub.10.1007/s10195-007-0166-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003962217
    153 https://doi.org/10.1007/s10195-007-0166-9
    154 rdf:type schema:CreativeWork
    155 https://app.dimensions.ai/details/publication/pub.1077724743 schema:CreativeWork
    156 https://doi.org/10.1016/j.arcmed.2010.08.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005906707
    157 rdf:type schema:CreativeWork
    158 https://doi.org/10.1016/j.clinbiomech.2007.07.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015174176
    159 rdf:type schema:CreativeWork
    160 https://doi.org/10.1016/j.clineuro.2014.10.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030431680
    161 rdf:type schema:CreativeWork
    162 https://doi.org/10.1016/j.injury.2012.04.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025932607
    163 rdf:type schema:CreativeWork
    164 https://doi.org/10.1016/j.jocn.2014.02.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008039209
    165 rdf:type schema:CreativeWork
    166 https://doi.org/10.1016/j.spinee.2017.06.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090319519
    167 rdf:type schema:CreativeWork
    168 https://doi.org/10.1016/j.wneu.2014.12.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040215245
    169 rdf:type schema:CreativeWork
    170 https://doi.org/10.1016/j.wneu.2017.08.179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091491843
    171 rdf:type schema:CreativeWork
    172 https://doi.org/10.1097/00007632-199710150-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028132890
    173 rdf:type schema:CreativeWork
    174 https://doi.org/10.1097/bsd.0000000000000328 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022327278
    175 rdf:type schema:CreativeWork
    176 https://doi.org/10.1097/bsd.0b013e3182867489 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047927275
    177 rdf:type schema:CreativeWork
    178 https://doi.org/10.12659/msm.901993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086256335
    179 rdf:type schema:CreativeWork
    180 https://doi.org/10.12659/msm.905466 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085986831
    181 rdf:type schema:CreativeWork
    182 https://doi.org/10.1371/journal.pone.0052910 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037345949
    183 rdf:type schema:CreativeWork
    184 https://doi.org/10.6061/clinics/2015(07)06 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013330855
    185 rdf:type schema:CreativeWork
    186 https://doi.org/10.7759/cureus.637 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049132452
    187 rdf:type schema:CreativeWork
    188 https://www.grid.ac/institutes/grid.414011.1 schema:alternateName Henan Provincial People's Hospital
    189 schema:name Department of Spine and Spinal Cord, Henan Provincial People’s Hospital, No.7, the Weft Fifth Road, Jinshui District, Zhengzhou, Henan, People’s Republic of China
    190 rdf:type schema:Organization
    191 https://www.grid.ac/institutes/grid.452672.0 schema:alternateName Second Affiliated Hospital of Xi'an Jiaotong University
    192 schema:name Department of Orthopedics, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China
    193 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...