Alpha-synuclein immunoreactive Lewy bodies and Lewy neurites in Parkinson’s disease are detectable by an advanced silver-staining technique View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-09

AUTHORS

Daniele Sandmann-Keil, H. Braak, Masayasu Okochi, Christian Haass, Eva Braak

ABSTRACT

Immunostaining with anti-α-synuclein is used to detect Lewy bodies and Lewy neurites in cases of Parkinson’s disease and related disorders. To prove that the result of a modern silver method is equivalent to that achieved with immunoreactions for α-synuclein, individual sections were successively processed using both methods. The silver-stained sections showed all of the immunoreactive Lewy bodies, and thin Lewy neurites were detected equally well by both techniques. The present study, therefore, points to the capabilities of a modern silver-staining method which is less time consuming and less expensive than immunocytochemical techniques. More... »

PAGES

461-464

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s004010051110

DOI

http://dx.doi.org/10.1007/s004010051110

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024680675

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10541868


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