Neurotropic virus infections as the cause of immediate and delayed neuropathology View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12-10

AUTHORS

Martin Ludlow, Jeroen Kortekaas, Christiane Herden, Bernd Hoffmann, Dennis Tappe, Corinna Trebst, Diane E. Griffin, Hannah E. Brindle, Tom Solomon, Alan S. Brown, Debby van Riel, Katja C. Wolthers, Dasja Pajkrt, Peter Wohlsein, Byron E. E. Martina, Wolfgang Baumgärtner, Georges M. Verjans, Albert D. M. E. Osterhaus

ABSTRACT

A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and neurological manifestations in humans and animals. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the central nervous system, frequently leaving the patient or affected animal with a poor or fatal prognosis. Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using examples of well-studied virus infections that are associated with these alterations in different populations throughout the world. A better understanding of the molecular, epidemiological and biological characteristics of these infections and in particular of mechanisms that underlie their clinical manifestations may be expected to provide tools for the development of more effective intervention strategies and treatment regimens. More... »

PAGES

159-184

References to SciGraph publications

  • 2010-07-16. Minocycline Differentially Modulates Viral Infection and Persistence in an Experimental Model of Japanese Encephalitis in JOURNAL OF NEUROIMMUNE PHARMACOLOGY
  • 2012-03-15. Human herpes virus 6-associated myelitis following allogeneic bone marrow transplantation in ANNALS OF HEMATOLOGY
  • 2012-01-31. Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder in MOLECULAR PSYCHIATRY
  • 2013-09-12. Molecular characterisation of virus in the brains of patients with measles inclusion body encephalitis (MIBE) in VIROLOGY JOURNAL
  • 1991-01. Acute ascending necrotizing myelitis in Okinawa caused by herpes simplex virus type 2 in VIRCHOWS ARCHIV A PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
  • 2012-03-18. Clinical and Pathological Manifestations of Human Henipavirus Infection in HENIPAVIRUS
  • 2011-01-26. The spatial epidemiology and clinical features of reported cases of La Crosse Virus infection in West Virginia from 2003 to 2007 in BMC INFECTIOUS DISEASES
  • 2013-02-14. Reduced viral burden in paralytic compared to furious canine rabies is associated with prominent inflammation at the brainstem level in BMC VETERINARY RESEARCH
  • 2010-01. Endogenous non-retroviral RNA virus elements in mammalian genomes in NATURE
  • 2002. Pathogenesis and Clinical Features of Japanese Encephalitis and West Nile Virus Infections in JAPANESE ENCEPHALITIS AND WEST NILE VIRUSES
  • 2011-07-22. Übertragung von Tollwut durch Organtransplantation in DIE PATHOLOGIE
  • 2005-09. Enteroviruses as agents of emerging infectious diseases in JOURNAL OF NEUROVIROLOGY
  • 1998-11. Distribution of measles virus in the central nervous system of HIV-seropositive children in ACTA NEUROPATHOLOGICA
  • 2008-07-31. Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: Identification of a candidate etiologic agent in VIROLOGY JOURNAL
  • 2013-10-20. Update on Herpes Virus Infections of the Nervous System in CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
  • 2014-05-13. Update on Varicella Zoster Virus Vasculopathy in CURRENT INFECTIOUS DISEASE REPORTS
  • 2012-01. Bats host major mammalian paramyxoviruses in NATURE COMMUNICATIONS
  • Journal

    TITLE

    Acta Neuropathologica

    ISSUE

    2

    VOLUME

    131

    Author Affiliations

  • Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559, Hannover, Germany
  • Department of Virology, Central Veterinary Institute, Part of Wageningen University and Research Centre, Wageningen, The Netherlands
  • Institute of Veterinary Pathology, Justus-Liebig-University Gießen, Giessen, Germany
  • Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
  • German Centre for Infection Research (DZIF), Hamburg, Germany
  • Department of Neurology, Hannover Medical School, Hannover, Germany
  • W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
  • Wellcome Trust Liverpool Glasgow Centre for Global Health Research, University of Liverpool, Liverpool, UK
  • NIHR Health Protection Research Unit in Emerging Infection and Zoonoses, Liverpool, UK
  • Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York, NY, USA
  • Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands
  • Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands
  • Department of Pediatric Infectious Diseases, Emma Children’s Hospital, Academic Medical Center, Amsterdam, The Netherlands
  • Department of Pathology, University of Veterinary Medicine, Hannover, Germany
  • Artemis One Health, Utrecht, The Netherlands
  • Center of Systems Neuroscience, Hannover, Germany
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00401-015-1511-3

    DOI

    http://dx.doi.org/10.1007/s00401-015-1511-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1038559752

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26659576


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