Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-06

AUTHORS

Thomas G. Beach, Charles H. Adler, Lucia I. Sue, Linda Vedders, LihFen Lue, Charles L. White III, Haru Akiyama, John N. Caviness, Holly A. Shill, Marwan N. Sabbagh, Douglas G. Walker, Arizona Parkinson’s Disease Consortium

ABSTRACT

A sensitive immunohistochemical method for phosphorylated alpha-synuclein was used to stain sets of sections of spinal cord and tissue from 41 different sites in the bodies of 92 subjects, including 23 normal elderly, 7 with incidental Lewy body disease (ILBD), 17 with Parkinson's disease (PD), 9 with dementia with Lewy bodies (DLB), 19 with Alzheimer's disease with Lewy bodies (ADLB) and 17 with Alzheimer's disease with no Lewy bodies (ADNLB). The relative densities and frequencies of occurrence of phosphorylated alpha-synuclein histopathology (PASH) were tabulated and correlated with diagnostic category. The greatest densities and frequencies of PASH occurred in the spinal cord, followed by the paraspinal sympathetic ganglia, the vagus nerve, the gastrointestinal tract and endocrine organs. The frequency of PASH within other organs and tissue types was much lower. Spinal cord and peripheral PASH was most common in subjects with PD and DLB, where it appears likely that it is universally widespread. Subjects with ILBD had lesser densities of PASH within all regions, but had frequent involvement of the spinal cord and paraspinal sympathetic ganglia, with less-frequent involvement of end-organs. Subjects with ADLB had infrequent involvement of the spinal cord and paraspinal sympathetic ganglia with rare involvement of end-organs. Within the gastrointestinal tract, there was a rostrocaudal gradient of decreasing PASH frequency and density, with the lower esophagus and submandibular gland having the greatest involvement and the colon and rectum the lowest. More... »

PAGES

689-702

References to SciGraph publications

  • 2008-05. Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease in NATURE MEDICINE
  • 2008-05. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation in NATURE MEDICINE
  • 2004-10. Stages in the development of Parkinson’s disease-related pathology in CELL AND TISSUE RESEARCH
  • 2008-09. Evaluation of α-synuclein immunohistochemical methods used by invited experts in ACTA NEUROPATHOLOGICA
  • 2008-09. The Sun Health Research Institute Brain Donation Program: Description and Eexperience, 1987–2007 in CELL AND TISSUE BANKING
  • 2008-07. Co-localization of tau and α-synuclein in the olfactory bulb in Alzheimer’s disease with amygdala Lewy bodies in ACTA NEUROPATHOLOGICA
  • 2009-06. Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction in ACTA NEUROPATHOLOGICA
  • 2000-10. Non-invasive assessment of swallowing and respiration in Parkonson's disease in JOURNAL OF NEUROLOGY
  • 2008-04. Applicability of current staging/categorization of α-synuclein pathology and their clinical relevance in ACTA NEUROPATHOLOGICA
  • 2007-04. Parkinson’s disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons in ACTA NEUROPATHOLOGICA
  • 2009-02. Olfactory bulb α-synucleinopathy has high specificity and sensitivity for Lewy body disorders in ACTA NEUROPATHOLOGICA
  • 2004-10. Lewy body-related α-synucleinopathy in the aged human brain in JOURNAL OF NEURAL TRANSMISSION
  • 1997-01. Pharyngo-Esophageal Dysphagia in Parkinson's Disease in DYSPHAGIA
  • 1990-04. Parkinson's disease: an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system in ACTA NEUROPATHOLOGICA
  • 2009-08. Gastrointestinal neuromuscular pathology: guidelines for histological techniques and reporting on behalf of the Gastro 2009 International Working Group in ACTA NEUROPATHOLOGICA
  • 2002-09. Microscopic analysis of polymerization dynamics with individual actin filaments in NATURE CELL BIOLOGY
  • 2002-02. α-Synuclein is phosphorylated in synucleinopathy lesions in NATURE CELL BIOLOGY
  • 2000-06. Brainstem-type Lewy body disease presenting with progressive autonomic failure and lethargy in CLINICAL AUTONOMIC RESEARCH
  • 1988-05. Parkinson's disease: the presence of Lewy bodies in Auerbach's and Meissner's plexuses in ACTA NEUROPATHOLOGICA
  • 2009-01. Lewy body pathology in long-term fetal nigral transplants: is parkinson's disease transmitted from one neural system to another? in NEUROPSYCHOPHARMACOLOGY
  • 1991-09. Neuropathological stageing of Alzheimer-related changes in ACTA NEUROPATHOLOGICA
  • 1997-08. The intermediolateral nucleus and Clarke’s column in Parkinson’s disease in ACTA NEUROPATHOLOGICA
  • 2003-04. Clinical and neuropathological correlates of Lewy body disease in ACTA NEUROPATHOLOGICA
  • 1993-09. Parkinson's disease with involvement of the parasympathetic ganglia in ACTA NEUROPATHOLOGICA
  • 2003-05. Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen in JOURNAL OF NEURAL TRANSMISSION
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00401-010-0664-3

    DOI

    http://dx.doi.org/10.1007/s00401-010-0664-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1050203734

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20306269


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