Impairing effect of fibrinogen on the mono-/bi-layer form of bovine lung surfactant View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-11

AUTHORS

Ravi Devraj, Kaushik Nag, Prasant Nahak, Kausik Manna, Mauricia Fritzen-Garcia, David W. Thompson, Kimiko Makino, Hiroyuki Ohshima, Hiromichi Nakahara, Osamu Shibata, Amiya Kumar Panda

ABSTRACT

Lung surfactant (LS), a lipid–protein mixture responsible for alveolar stability, is inhibited by serum proteins leaked into the lungs in disease. Interaction of bovine lipid extract surfactant (BLES), a clinical replacement lung surfactant, with serum protein fibrinogen (Fbg) was studied employing various structural and biophysical techniques in adsorbed films and bulk bilayer dispersions. Surface tension area isotherms of the adsorbed films revealed the suppression of interfacial activity of BLES by Fbg (adsorption and surface tension reduction). Fbg, predominantly associated with the fluid phase of BLES films, resulted in the aggregation of the gel lipid domains as evidenced by atomic force microscopy. BLES bilayer dispersion showed phase transition from a diffused gel to liquid–crystalline phase in the temperature range 10–35 °C as studied by differential scanning calorimetry (DSC). Fbg resulted in the shift of peak to a higher transition temperature for the maximal heat flow (Tmax) of BLES dispersions. Combined Raman and FTIR spectral studies of the BLES/Fbg dispersions revealed that Fbg altered the –CH2–, –CH3, and –PO4− vibrational modes of the phospholipids present in BLES, suggesting the condensing and dehydrating effect of the protein on surfactant. Studies suggest that Fbg, by directly interacting with the gel lipids in LS in bulk dispersions, alter the packing of the films formed at the interface, and can be used as a specific model for lung disease. More... »

PAGES

2765-2774

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00396-014-3319-4

DOI

http://dx.doi.org/10.1007/s00396-014-3319-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026778353


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0306", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Chemistry (incl. Structural)", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Memorial University of Newfoundland", 
          "id": "https://www.grid.ac/institutes/grid.25055.37", 
          "name": [
            "Department of Biochemistry, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Devraj", 
        "givenName": "Ravi", 
        "id": "sg:person.0617032127.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617032127.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Memorial University of Newfoundland", 
          "id": "https://www.grid.ac/institutes/grid.25055.37", 
          "name": [
            "Department of Biochemistry, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nag", 
        "givenName": "Kaushik", 
        "id": "sg:person.01235740406.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235740406.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "North Bengal University", 
          "id": "https://www.grid.ac/institutes/grid.412222.5", 
          "name": [
            "Department of Chemistry, University of North Bengal, 734013, Darjeeling, West Bengal, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nahak", 
        "givenName": "Prasant", 
        "id": "sg:person.01035236116.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035236116.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "North Bengal University", 
          "id": "https://www.grid.ac/institutes/grid.412222.5", 
          "name": [
            "Department of Chemistry, University of North Bengal, 734013, Darjeeling, West Bengal, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Manna", 
        "givenName": "Kausik", 
        "id": "sg:person.010312504051.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010312504051.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Memorial University of Newfoundland", 
          "id": "https://www.grid.ac/institutes/grid.25055.37", 
          "name": [
            "Department of Biochemistry, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fritzen-Garcia", 
        "givenName": "Mauricia", 
        "id": "sg:person.01041326233.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041326233.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Memorial University of Newfoundland", 
          "id": "https://www.grid.ac/institutes/grid.25055.37", 
          "name": [
            "Department of Chemistry, Memorial University of Newfoundland, St. John\u2019s, Newfoundland, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thompson", 
        "givenName": "David W.", 
        "id": "sg:person.01265713116.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265713116.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo University of Science", 
          "id": "https://www.grid.ac/institutes/grid.143643.7", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda Campus, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Makino", 
        "givenName": "Kimiko", 
        "id": "sg:person.01221563640.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221563640.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo University of Science", 
          "id": "https://www.grid.ac/institutes/grid.143643.7", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda Campus, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ohshima", 
        "givenName": "Hiroyuki", 
        "id": "sg:person.011310560407.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011310560407.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki International University", 
          "id": "https://www.grid.ac/institutes/grid.411871.a", 
          "name": [
            "Department of Biophysical Chemistry, Faculty of Pharmaceutical Sciences, Nagasaki International University, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakahara", 
        "givenName": "Hiromichi", 
        "id": "sg:person.0711415345.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0711415345.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki International University", 
          "id": "https://www.grid.ac/institutes/grid.411871.a", 
          "name": [
            "Department of Biophysical Chemistry, Faculty of Pharmaceutical Sciences, Nagasaki International University, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shibata", 
        "givenName": "Osamu", 
        "id": "sg:person.0627603227.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627603227.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "North Bengal University", 
          "id": "https://www.grid.ac/institutes/grid.412222.5", 
          "name": [
            "Department of Chemistry, University of North Bengal, 734013, Darjeeling, West Bengal, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Panda", 
        "givenName": "Amiya Kumar", 
        "id": "sg:person.0614512333.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614512333.63"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1139/y88-192", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000057586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/315253a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000748071", 
          "https://doi.org/10.1038/315253a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/315253a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000748071", 
          "https://doi.org/10.1038/315253a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(02)75552-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002166930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/y89-106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002191431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2760(93)90143-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002479152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2760(93)90143-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002479152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.resp.2013.02.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006897305"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.vibspec.2012.10.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008762730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/9780470388495.ch15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012874453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2760(84)90310-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015906339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2760(84)90310-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015906339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(98)78005-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017869102"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1165/rcmb.2003-0279oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022012978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.b.30842", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023876489"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.colsurfb.2013.09.034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024742304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.resp.2007.02.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024956262"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2736(76)90437-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026453388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2736(76)90437-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026453388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0009-3084(98)00080-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028624323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1034/j.1399-3003.2000.15.17.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029525479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.colsurfb.2009.06.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029920019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcis.2010.08.058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030767360"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00396-002-0677-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037513566", 
          "https://doi.org/10.1007/s00396-002-0677-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2736(87)90130-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038605445"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2736(87)90130-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038605445"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02535391", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044286611", 
          "https://doi.org/10.1007/bf02535391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.nano.2011.08.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046239879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbamem.2007.10.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046924689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbamem.2012.05.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051653164"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(00)76588-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053399946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi963040h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055213336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi963040h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055213336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/09031936.99.13614779", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064124078"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3891/acta.chem.scand.04-0351", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071486036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1987.62.2.429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079820535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1103193090", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-11", 
    "datePublishedReg": "2014-11-01", 
    "description": "Lung surfactant (LS), a lipid\u2013protein mixture responsible for alveolar stability, is inhibited by serum proteins leaked into the lungs in disease. Interaction of bovine lipid extract surfactant (BLES), a clinical replacement lung surfactant, with serum protein fibrinogen (Fbg) was studied employing various structural and biophysical techniques in adsorbed films and bulk bilayer dispersions. Surface tension area isotherms of the adsorbed films revealed the suppression of interfacial activity of BLES by Fbg (adsorption and surface tension reduction). Fbg, predominantly associated with the fluid phase of BLES films, resulted in the aggregation of the gel lipid domains as evidenced by atomic force microscopy. BLES bilayer dispersion showed phase transition from a diffused gel to liquid\u2013crystalline phase in the temperature range 10\u201335 \u00b0C as studied by differential scanning calorimetry (DSC). Fbg resulted in the shift of peak to a higher transition temperature for the maximal heat flow (Tmax) of BLES dispersions. Combined Raman and FTIR spectral studies of the BLES/Fbg dispersions revealed that Fbg altered the \u2013CH2\u2013, \u2013CH3, and \u2013PO4\u2212 vibrational modes of the phospholipids present in BLES, suggesting the condensing and dehydrating effect of the protein on surfactant. Studies suggest that Fbg, by directly interacting with the gel lipids in LS in bulk dispersions, alter the packing of the films formed at the interface, and can be used as a specific model for lung disease.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00396-014-3319-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6139556", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6126901", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1083512", 
        "issn": [
          "0303-402X", 
          "1435-1536"
        ], 
        "name": "Colloid and Polymer Science", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "292"
      }
    ], 
    "name": "Impairing effect of fibrinogen on the mono-/bi-layer form of bovine lung surfactant", 
    "pagination": "2765-2774", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "7f91b4b968587e428b0330620c4f9add9b6e2f01a267d977240be9a978a3133f"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00396-014-3319-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1026778353"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00396-014-3319-4", 
      "https://app.dimensions.ai/details/publication/pub.1026778353"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000587.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00396-014-3319-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00396-014-3319-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00396-014-3319-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00396-014-3319-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00396-014-3319-4'


 

This table displays all metadata directly associated to this object as RDF triples.

240 TRIPLES      21 PREDICATES      58 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00396-014-3319-4 schema:about anzsrc-for:03
2 anzsrc-for:0306
3 schema:author N2abc7fe9d55f4280b58f2f130b683da2
4 schema:citation sg:pub.10.1007/bf02535391
5 sg:pub.10.1007/s00396-002-0677-0
6 sg:pub.10.1038/315253a0
7 https://app.dimensions.ai/details/publication/pub.1103193090
8 https://doi.org/10.1002/9780470388495.ch15
9 https://doi.org/10.1002/jbm.b.30842
10 https://doi.org/10.1016/0005-2736(76)90437-5
11 https://doi.org/10.1016/0005-2736(87)90130-1
12 https://doi.org/10.1016/0005-2760(84)90310-2
13 https://doi.org/10.1016/0005-2760(93)90143-w
14 https://doi.org/10.1016/j.bbamem.2007.10.027
15 https://doi.org/10.1016/j.bbamem.2012.05.024
16 https://doi.org/10.1016/j.colsurfb.2009.06.013
17 https://doi.org/10.1016/j.colsurfb.2013.09.034
18 https://doi.org/10.1016/j.jcis.2010.08.058
19 https://doi.org/10.1016/j.nano.2011.08.004
20 https://doi.org/10.1016/j.resp.2007.02.001
21 https://doi.org/10.1016/j.resp.2013.02.030
22 https://doi.org/10.1016/j.vibspec.2012.10.008
23 https://doi.org/10.1016/s0006-3495(00)76588-x
24 https://doi.org/10.1016/s0006-3495(02)75552-5
25 https://doi.org/10.1016/s0006-3495(98)78005-1
26 https://doi.org/10.1016/s0009-3084(98)00080-2
27 https://doi.org/10.1021/bi963040h
28 https://doi.org/10.1034/j.1399-3003.2000.15.17.x
29 https://doi.org/10.1139/y88-192
30 https://doi.org/10.1139/y89-106
31 https://doi.org/10.1152/jappl.1987.62.2.429
32 https://doi.org/10.1165/rcmb.2003-0279oc
33 https://doi.org/10.1183/09031936.99.13614779
34 https://doi.org/10.3891/acta.chem.scand.04-0351
35 schema:datePublished 2014-11
36 schema:datePublishedReg 2014-11-01
37 schema:description Lung surfactant (LS), a lipid–protein mixture responsible for alveolar stability, is inhibited by serum proteins leaked into the lungs in disease. Interaction of bovine lipid extract surfactant (BLES), a clinical replacement lung surfactant, with serum protein fibrinogen (Fbg) was studied employing various structural and biophysical techniques in adsorbed films and bulk bilayer dispersions. Surface tension area isotherms of the adsorbed films revealed the suppression of interfacial activity of BLES by Fbg (adsorption and surface tension reduction). Fbg, predominantly associated with the fluid phase of BLES films, resulted in the aggregation of the gel lipid domains as evidenced by atomic force microscopy. BLES bilayer dispersion showed phase transition from a diffused gel to liquid–crystalline phase in the temperature range 10–35 °C as studied by differential scanning calorimetry (DSC). Fbg resulted in the shift of peak to a higher transition temperature for the maximal heat flow (Tmax) of BLES dispersions. Combined Raman and FTIR spectral studies of the BLES/Fbg dispersions revealed that Fbg altered the –CH2–, –CH3, and –PO4− vibrational modes of the phospholipids present in BLES, suggesting the condensing and dehydrating effect of the protein on surfactant. Studies suggest that Fbg, by directly interacting with the gel lipids in LS in bulk dispersions, alter the packing of the films formed at the interface, and can be used as a specific model for lung disease.
38 schema:genre research_article
39 schema:inLanguage en
40 schema:isAccessibleForFree false
41 schema:isPartOf Nc8bac6423ece47e8880152171c59fbd3
42 Nce610ef907f449478752c85844f77ab3
43 sg:journal.1083512
44 schema:name Impairing effect of fibrinogen on the mono-/bi-layer form of bovine lung surfactant
45 schema:pagination 2765-2774
46 schema:productId N69ff5f11e5e84ac9a8f13308bbb2111d
47 N7c66378288ce43298c3fbbfc2db97b0c
48 N8e3edb107e0348078c2499b55d7710cf
49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026778353
50 https://doi.org/10.1007/s00396-014-3319-4
51 schema:sdDatePublished 2019-04-10T16:02
52 schema:sdLicense https://scigraph.springernature.com/explorer/license/
53 schema:sdPublisher Ne68a1ac921284a24ba4a3d9bffea2fe8
54 schema:url http://link.springer.com/10.1007%2Fs00396-014-3319-4
55 sgo:license sg:explorer/license/
56 sgo:sdDataset articles
57 rdf:type schema:ScholarlyArticle
58 N2abc7fe9d55f4280b58f2f130b683da2 rdf:first sg:person.0617032127.02
59 rdf:rest N5c07934fb3f94b5388ccdd517ac7c1e0
60 N339042693d1a4860beed4374794b7f06 rdf:first sg:person.0614512333.63
61 rdf:rest rdf:nil
62 N39966a512a6c4e34bf13dd6dba608f74 rdf:first sg:person.010312504051.47
63 rdf:rest N910cc7f6c2d543f3bde68064fb1b5907
64 N5c07934fb3f94b5388ccdd517ac7c1e0 rdf:first sg:person.01235740406.63
65 rdf:rest Ndc944e30773646d5a3bbac74d5e8395b
66 N69ff5f11e5e84ac9a8f13308bbb2111d schema:name doi
67 schema:value 10.1007/s00396-014-3319-4
68 rdf:type schema:PropertyValue
69 N7c66378288ce43298c3fbbfc2db97b0c schema:name dimensions_id
70 schema:value pub.1026778353
71 rdf:type schema:PropertyValue
72 N87af794e0d56497582b44ecbf89fa1e9 rdf:first sg:person.0627603227.56
73 rdf:rest N339042693d1a4860beed4374794b7f06
74 N8cf71625802e47378efbe808e523b144 rdf:first sg:person.01221563640.34
75 rdf:rest Nd2e2e92eba3f4037b47c6f427e74bc8c
76 N8e3edb107e0348078c2499b55d7710cf schema:name readcube_id
77 schema:value 7f91b4b968587e428b0330620c4f9add9b6e2f01a267d977240be9a978a3133f
78 rdf:type schema:PropertyValue
79 N910cc7f6c2d543f3bde68064fb1b5907 rdf:first sg:person.01041326233.76
80 rdf:rest Nffa20a13cd274b0d8f118497c6f7e584
81 N9e612dbb8d36495e90653323fabaf8f3 rdf:first sg:person.0711415345.51
82 rdf:rest N87af794e0d56497582b44ecbf89fa1e9
83 Nc8bac6423ece47e8880152171c59fbd3 schema:issueNumber 11
84 rdf:type schema:PublicationIssue
85 Nce610ef907f449478752c85844f77ab3 schema:volumeNumber 292
86 rdf:type schema:PublicationVolume
87 Nd2e2e92eba3f4037b47c6f427e74bc8c rdf:first sg:person.011310560407.62
88 rdf:rest N9e612dbb8d36495e90653323fabaf8f3
89 Ndc944e30773646d5a3bbac74d5e8395b rdf:first sg:person.01035236116.42
90 rdf:rest N39966a512a6c4e34bf13dd6dba608f74
91 Ne68a1ac921284a24ba4a3d9bffea2fe8 schema:name Springer Nature - SN SciGraph project
92 rdf:type schema:Organization
93 Nffa20a13cd274b0d8f118497c6f7e584 rdf:first sg:person.01265713116.35
94 rdf:rest N8cf71625802e47378efbe808e523b144
95 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
96 schema:name Chemical Sciences
97 rdf:type schema:DefinedTerm
98 anzsrc-for:0306 schema:inDefinedTermSet anzsrc-for:
99 schema:name Physical Chemistry (incl. Structural)
100 rdf:type schema:DefinedTerm
101 sg:grant.6126901 http://pending.schema.org/fundedItem sg:pub.10.1007/s00396-014-3319-4
102 rdf:type schema:MonetaryGrant
103 sg:grant.6139556 http://pending.schema.org/fundedItem sg:pub.10.1007/s00396-014-3319-4
104 rdf:type schema:MonetaryGrant
105 sg:journal.1083512 schema:issn 0303-402X
106 1435-1536
107 schema:name Colloid and Polymer Science
108 rdf:type schema:Periodical
109 sg:person.010312504051.47 schema:affiliation https://www.grid.ac/institutes/grid.412222.5
110 schema:familyName Manna
111 schema:givenName Kausik
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010312504051.47
113 rdf:type schema:Person
114 sg:person.01035236116.42 schema:affiliation https://www.grid.ac/institutes/grid.412222.5
115 schema:familyName Nahak
116 schema:givenName Prasant
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035236116.42
118 rdf:type schema:Person
119 sg:person.01041326233.76 schema:affiliation https://www.grid.ac/institutes/grid.25055.37
120 schema:familyName Fritzen-Garcia
121 schema:givenName Mauricia
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041326233.76
123 rdf:type schema:Person
124 sg:person.011310560407.62 schema:affiliation https://www.grid.ac/institutes/grid.143643.7
125 schema:familyName Ohshima
126 schema:givenName Hiroyuki
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011310560407.62
128 rdf:type schema:Person
129 sg:person.01221563640.34 schema:affiliation https://www.grid.ac/institutes/grid.143643.7
130 schema:familyName Makino
131 schema:givenName Kimiko
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221563640.34
133 rdf:type schema:Person
134 sg:person.01235740406.63 schema:affiliation https://www.grid.ac/institutes/grid.25055.37
135 schema:familyName Nag
136 schema:givenName Kaushik
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235740406.63
138 rdf:type schema:Person
139 sg:person.01265713116.35 schema:affiliation https://www.grid.ac/institutes/grid.25055.37
140 schema:familyName Thompson
141 schema:givenName David W.
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265713116.35
143 rdf:type schema:Person
144 sg:person.0614512333.63 schema:affiliation https://www.grid.ac/institutes/grid.412222.5
145 schema:familyName Panda
146 schema:givenName Amiya Kumar
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614512333.63
148 rdf:type schema:Person
149 sg:person.0617032127.02 schema:affiliation https://www.grid.ac/institutes/grid.25055.37
150 schema:familyName Devraj
151 schema:givenName Ravi
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617032127.02
153 rdf:type schema:Person
154 sg:person.0627603227.56 schema:affiliation https://www.grid.ac/institutes/grid.411871.a
155 schema:familyName Shibata
156 schema:givenName Osamu
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627603227.56
158 rdf:type schema:Person
159 sg:person.0711415345.51 schema:affiliation https://www.grid.ac/institutes/grid.411871.a
160 schema:familyName Nakahara
161 schema:givenName Hiromichi
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0711415345.51
163 rdf:type schema:Person
164 sg:pub.10.1007/bf02535391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044286611
165 https://doi.org/10.1007/bf02535391
166 rdf:type schema:CreativeWork
167 sg:pub.10.1007/s00396-002-0677-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037513566
168 https://doi.org/10.1007/s00396-002-0677-0
169 rdf:type schema:CreativeWork
170 sg:pub.10.1038/315253a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000748071
171 https://doi.org/10.1038/315253a0
172 rdf:type schema:CreativeWork
173 https://app.dimensions.ai/details/publication/pub.1103193090 schema:CreativeWork
174 https://doi.org/10.1002/9780470388495.ch15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012874453
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1002/jbm.b.30842 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023876489
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/0005-2736(76)90437-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026453388
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1016/0005-2736(87)90130-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038605445
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/0005-2760(84)90310-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015906339
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/0005-2760(93)90143-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1002479152
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/j.bbamem.2007.10.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046924689
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/j.bbamem.2012.05.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051653164
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/j.colsurfb.2009.06.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029920019
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/j.colsurfb.2013.09.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024742304
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/j.jcis.2010.08.058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030767360
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/j.nano.2011.08.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046239879
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.resp.2007.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024956262
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/j.resp.2013.02.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006897305
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/j.vibspec.2012.10.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008762730
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/s0006-3495(00)76588-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053399946
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/s0006-3495(02)75552-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002166930
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/s0006-3495(98)78005-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017869102
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/s0009-3084(98)00080-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028624323
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1021/bi963040h schema:sameAs https://app.dimensions.ai/details/publication/pub.1055213336
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1034/j.1399-3003.2000.15.17.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029525479
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1139/y88-192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000057586
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1139/y89-106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002191431
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1152/jappl.1987.62.2.429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079820535
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1165/rcmb.2003-0279oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1022012978
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1183/09031936.99.13614779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064124078
225 rdf:type schema:CreativeWork
226 https://doi.org/10.3891/acta.chem.scand.04-0351 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071486036
227 rdf:type schema:CreativeWork
228 https://www.grid.ac/institutes/grid.143643.7 schema:alternateName Tokyo University of Science
229 schema:name Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda Campus, Chiba, Japan
230 rdf:type schema:Organization
231 https://www.grid.ac/institutes/grid.25055.37 schema:alternateName Memorial University of Newfoundland
232 schema:name Department of Biochemistry, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada
233 Department of Chemistry, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada
234 rdf:type schema:Organization
235 https://www.grid.ac/institutes/grid.411871.a schema:alternateName Nagasaki International University
236 schema:name Department of Biophysical Chemistry, Faculty of Pharmaceutical Sciences, Nagasaki International University, Nagasaki, Japan
237 rdf:type schema:Organization
238 https://www.grid.ac/institutes/grid.412222.5 schema:alternateName North Bengal University
239 schema:name Department of Chemistry, University of North Bengal, 734013, Darjeeling, West Bengal, India
240 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...