Calcium and vitamin D supplementation through fortified dairy products counterbalances seasonal variations of bone metabolism indices: the Postmenopausal Health Study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-08

AUTHORS

Roxane Tenta, George Moschonis, Michael Koutsilieris, Yannis Manios

ABSTRACT

PURPOSE: To assess the effectiveness of a dietary intervention combined with fortified dairy products on bone metabolism and bone mass indices in postmenopausal women. METHODS: Forty postmenopausal women (55-65 years old) were equally randomized into a dietary group (DG), receiving daily and for 30 months, 1,200 mg of calcium and 7.5 μg of vitamin D(3) for the first 12 months that increased to 22.5 μg for the remaining 18 months of intervention through fortified dairy products; and a control group (CG). Differences in the changes of bone metabolism and bone mass indices were examined with repeated measures ANOVA. RESULTS: A significant increase was observed for PTH levels only in the CG during the first six winter months of intervention (p = 0.049). After 30 months of intervention, during winter, serum 25(OH)D significantly decreased in the CG while remained in the same high levels as in the summer period in the DG. Serum RANKL levels decreased significantly in the DG compared with the increase in the CG during the 30-month intervention period (p = 0.005). Serum CTx decreased significantly in the DG after six (-0.08; -0.12 to -0.03) and 12 (-0.03; -0.08 to -0.02) months of intervention. Finally, the DG had more favorable changes in total body BMD than the CG (p < 0.001). CONCLUSIONS: Increasing dietary intake of calcium and vitamin D in osteopenic postmenopausal women appears to be effective in producing favorable changes in several bone metabolism and bone mass indices and in counterbalancing seasonal variations in hormonal and biochemical molecules. More... »

PAGES

341-349

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00394-010-0142-7

DOI

http://dx.doi.org/10.1007/s00394-010-0142-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036858365

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21153900


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Density", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone and Bones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium, Dietary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dairy Products", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diet", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dietary Supplements", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Energy Intake", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Food, Fortified", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Greece", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Holistic Health", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Life Style", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Motor Activity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nutrition Assessment", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Postmenopause", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RANK Ligand", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Seasons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vitamin D", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vitamins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Harokopio University", 
          "id": "https://www.grid.ac/institutes/grid.15823.3d", 
          "name": [
            "Department of Nutrition and Dietetics, Harokopio University, 70, El.Venizelou Ave, 176 71 Kallithea, Athens, Greece"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tenta", 
        "givenName": "Roxane", 
        "id": "sg:person.01125531320.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125531320.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harokopio University", 
          "id": "https://www.grid.ac/institutes/grid.15823.3d", 
          "name": [
            "Department of Nutrition and Dietetics, Harokopio University, 70, El.Venizelou Ave, 176 71 Kallithea, Athens, Greece"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moschonis", 
        "givenName": "George", 
        "id": "sg:person.01016755660.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016755660.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National and Kapodistrian University of Athens", 
          "id": "https://www.grid.ac/institutes/grid.5216.0", 
          "name": [
            "Department of Experimental Physiology, Medical School, University of Athens, 75 Micras Asias, 115 27, Goudi-Athens, Greece"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koutsilieris", 
        "givenName": "Michael", 
        "id": "sg:person.0733537100.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733537100.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harokopio University", 
          "id": "https://www.grid.ac/institutes/grid.15823.3d", 
          "name": [
            "Department of Nutrition and Dietetics, Harokopio University, 70, El.Venizelou Ave, 176 71 Kallithea, Athens, Greece"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Manios", 
        "givenName": "Yannis", 
        "id": "sg:person.01264414106.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264414106.95"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s8756-3282(02)00853-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003446942"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s8756-3282(02)00853-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003446942"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199009273231305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008147081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1185/03007991003659814", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013955274"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s000711451000019x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015063926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4158/ep.9.6.544", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015983244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1359/jbmr.080201", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016075536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9343(99)80310-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016498352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbcan.2004.05.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017453309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.dinthera.2005.03.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021322501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.dinthera.2005.03.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021322501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s001980070005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024411521", 
          "https://doi.org/10.1007/s001980070005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00198-003-1448-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024758573", 
          "https://doi.org/10.1007/s00198-003-1448-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s001980050062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025292854", 
          "https://doi.org/10.1007/s001980050062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1359/jbmr.2000.15.11.2276", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025477338"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.autrev.2010.06.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034863625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.292.4.490", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039057059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-8223(99)00302-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039240934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-8223(99)00302-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039240934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.c3691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041990973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1196/annals.1365.035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045455492"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199709043371003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047469735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1359/jbmr.1998.13.2.168", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050506060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2458-4-66", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053174238", 
          "https://doi.org/10.1186/1471-2458-4-66"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1123/pes.9.2.159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062434967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.83.11.3817", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064299918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-128-10-199805150-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073701846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-152-5-201003020-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073711386"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/73.2.288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074750794"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/77.1.204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075208306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jn/135.2.310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076998587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/81.5.1232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077050123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077408716", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/86.3.781", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077478546"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/87.6.1952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077659037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082581793", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-08", 
    "datePublishedReg": "2011-08-01", 
    "description": "PURPOSE: To assess the effectiveness of a dietary intervention combined with fortified dairy products on bone metabolism and bone mass indices in postmenopausal women.\nMETHODS: Forty postmenopausal women (55-65 years old) were equally randomized into a dietary group (DG), receiving daily and for 30 months, 1,200 mg of calcium and 7.5 \u03bcg of vitamin D(3) for the first 12 months that increased to 22.5 \u03bcg for the remaining 18 months of intervention through fortified dairy products; and a control group (CG). Differences in the changes of bone metabolism and bone mass indices were examined with repeated measures ANOVA.\nRESULTS: A significant increase was observed for PTH levels only in the CG during the first six winter months of intervention (p = 0.049). After 30 months of intervention, during winter, serum 25(OH)D significantly decreased in the CG while remained in the same high levels as in the summer period in the DG. Serum RANKL levels decreased significantly in the DG compared with the increase in the CG during the 30-month intervention period (p = 0.005). Serum CTx decreased significantly in the DG after six (-0.08; -0.12 to -0.03) and 12 (-0.03; -0.08 to -0.02) months of intervention. Finally, the DG had more favorable changes in total body BMD than the CG (p < 0.001).\nCONCLUSIONS: Increasing dietary intake of calcium and vitamin D in osteopenic postmenopausal women appears to be effective in producing favorable changes in several bone metabolism and bone mass indices and in counterbalancing seasonal variations in hormonal and biochemical molecules.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00394-010-0142-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1294989", 
        "issn": [
          "1436-6207", 
          "1435-1293"
        ], 
        "name": "European Journal of Nutrition", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "50"
      }
    ], 
    "name": "Calcium and vitamin D supplementation through fortified dairy products counterbalances seasonal variations of bone metabolism indices: the Postmenopausal Health Study", 
    "pagination": "341-349", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "af945013e39b015589ba9152364f307f8a57f904a5128a6e9ed14305cb633f32"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21153900"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100888704"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00394-010-0142-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036858365"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00394-010-0142-7", 
      "https://app.dimensions.ai/details/publication/pub.1036858365"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:09", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000514.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00394-010-0142-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00394-010-0142-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00394-010-0142-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00394-010-0142-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00394-010-0142-7'


 

This table displays all metadata directly associated to this object as RDF triples.

286 TRIPLES      21 PREDICATES      85 URIs      44 LITERALS      32 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00394-010-0142-7 schema:about N131defa2456d4ba79d3343717e80220f
2 N1d09ec70c1774379bd2162ef72473fef
3 N225229be20144b6aae2c1a9285828b35
4 N242b95954b6b4f3e99078701667c93a5
5 N2aa710a47f0848fba703fc6ac3373676
6 N3461dc90e6ca4605a53f29fba104931a
7 N4ba3a408f1a44d21a684f7919cdde320
8 N4e6e679a73c14c219ef2d7fdea87d799
9 N61a21b5a4dcd42049f2de2f974631ed1
10 N6d07da8d36a84f7fa60b5e7a3d008855
11 N6d8f1c87f3704ca2b324476d1e580f15
12 N7bcc1f4561514044b998e896bea02e50
13 N86cd5622cfc441a4ad453db89c433ada
14 N97afe470008f42d0be1853993b5f880a
15 N9a57d4b6709f44b2bee069627e2c93e3
16 N9db0928c949e439cab7d5cd9c25ce7bf
17 N9e8eef106fd749c898d71b75d03c8a5b
18 Na34d31cdb8584a30925cd2ee2ea6cfec
19 Nb7eee512c0304d4d81c9d47a56e181dc
20 Nbb3780fec96a42fe94493b9daef42b58
21 Ne84d2c23cc604ccd9a0bcfe683a87b22
22 Nf477e56d514c455d92280b9f6ba085f4
23 Nf57e70064c69445c94a650c095f50128
24 anzsrc-for:11
25 anzsrc-for:1103
26 schema:author N2d122c6e15054cedb829cf9028f0dfdd
27 schema:citation sg:pub.10.1007/s00198-003-1448-6
28 sg:pub.10.1007/s001980050062
29 sg:pub.10.1007/s001980070005
30 sg:pub.10.1186/1471-2458-4-66
31 https://app.dimensions.ai/details/publication/pub.1077408716
32 https://app.dimensions.ai/details/publication/pub.1082581793
33 https://doi.org/10.1001/jama.292.4.490
34 https://doi.org/10.1016/j.autrev.2010.06.009
35 https://doi.org/10.1016/j.bbcan.2004.05.002
36 https://doi.org/10.1016/j.dinthera.2005.03.003
37 https://doi.org/10.1016/s0002-8223(99)00302-8
38 https://doi.org/10.1016/s0002-9343(99)80310-6
39 https://doi.org/10.1016/s8756-3282(02)00853-0
40 https://doi.org/10.1017/s000711451000019x
41 https://doi.org/10.1056/nejm199009273231305
42 https://doi.org/10.1056/nejm199709043371003
43 https://doi.org/10.1093/ajcn/73.2.288
44 https://doi.org/10.1093/ajcn/77.1.204
45 https://doi.org/10.1093/ajcn/81.5.1232
46 https://doi.org/10.1093/ajcn/86.3.781
47 https://doi.org/10.1093/ajcn/87.6.1952
48 https://doi.org/10.1093/jn/135.2.310
49 https://doi.org/10.1123/pes.9.2.159
50 https://doi.org/10.1136/bmj.c3691
51 https://doi.org/10.1185/03007991003659814
52 https://doi.org/10.1196/annals.1365.035
53 https://doi.org/10.1210/jc.83.11.3817
54 https://doi.org/10.1359/jbmr.080201
55 https://doi.org/10.1359/jbmr.1998.13.2.168
56 https://doi.org/10.1359/jbmr.2000.15.11.2276
57 https://doi.org/10.4158/ep.9.6.544
58 https://doi.org/10.7326/0003-4819-128-10-199805150-00002
59 https://doi.org/10.7326/0003-4819-152-5-201003020-00010
60 schema:datePublished 2011-08
61 schema:datePublishedReg 2011-08-01
62 schema:description PURPOSE: To assess the effectiveness of a dietary intervention combined with fortified dairy products on bone metabolism and bone mass indices in postmenopausal women. METHODS: Forty postmenopausal women (55-65 years old) were equally randomized into a dietary group (DG), receiving daily and for 30 months, 1,200 mg of calcium and 7.5 μg of vitamin D(3) for the first 12 months that increased to 22.5 μg for the remaining 18 months of intervention through fortified dairy products; and a control group (CG). Differences in the changes of bone metabolism and bone mass indices were examined with repeated measures ANOVA. RESULTS: A significant increase was observed for PTH levels only in the CG during the first six winter months of intervention (p = 0.049). After 30 months of intervention, during winter, serum 25(OH)D significantly decreased in the CG while remained in the same high levels as in the summer period in the DG. Serum RANKL levels decreased significantly in the DG compared with the increase in the CG during the 30-month intervention period (p = 0.005). Serum CTx decreased significantly in the DG after six (-0.08; -0.12 to -0.03) and 12 (-0.03; -0.08 to -0.02) months of intervention. Finally, the DG had more favorable changes in total body BMD than the CG (p < 0.001). CONCLUSIONS: Increasing dietary intake of calcium and vitamin D in osteopenic postmenopausal women appears to be effective in producing favorable changes in several bone metabolism and bone mass indices and in counterbalancing seasonal variations in hormonal and biochemical molecules.
63 schema:genre research_article
64 schema:inLanguage en
65 schema:isAccessibleForFree false
66 schema:isPartOf N1557e171667149b98df420d5229532f2
67 Ncd4b393c32c4433f9942241bf6bdcc81
68 sg:journal.1294989
69 schema:name Calcium and vitamin D supplementation through fortified dairy products counterbalances seasonal variations of bone metabolism indices: the Postmenopausal Health Study
70 schema:pagination 341-349
71 schema:productId N112d1d17c4d5418998442d31c5dad7ce
72 N1fe286a704aa45c3873425c1c69e439a
73 N838fe790b8c14ca9b89f9a8ca5f0d8f7
74 N843bc8337d0441eb89045f35e1d88c5f
75 Nbf608e2aa76142b8b2bd0bdb2a9602ef
76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036858365
77 https://doi.org/10.1007/s00394-010-0142-7
78 schema:sdDatePublished 2019-04-10T19:09
79 schema:sdLicense https://scigraph.springernature.com/explorer/license/
80 schema:sdPublisher N783ee42526464d4cba98da46d0c385f7
81 schema:url http://link.springer.com/10.1007%2Fs00394-010-0142-7
82 sgo:license sg:explorer/license/
83 sgo:sdDataset articles
84 rdf:type schema:ScholarlyArticle
85 N112d1d17c4d5418998442d31c5dad7ce schema:name nlm_unique_id
86 schema:value 100888704
87 rdf:type schema:PropertyValue
88 N131defa2456d4ba79d3343717e80220f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Motor Activity
90 rdf:type schema:DefinedTerm
91 N1557e171667149b98df420d5229532f2 schema:volumeNumber 50
92 rdf:type schema:PublicationVolume
93 N1d09ec70c1774379bd2162ef72473fef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Humans
95 rdf:type schema:DefinedTerm
96 N1fe286a704aa45c3873425c1c69e439a schema:name pubmed_id
97 schema:value 21153900
98 rdf:type schema:PropertyValue
99 N225229be20144b6aae2c1a9285828b35 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Female
101 rdf:type schema:DefinedTerm
102 N242b95954b6b4f3e99078701667c93a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Diet
104 rdf:type schema:DefinedTerm
105 N2aa710a47f0848fba703fc6ac3373676 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Bone Density
107 rdf:type schema:DefinedTerm
108 N2d122c6e15054cedb829cf9028f0dfdd rdf:first sg:person.01125531320.59
109 rdf:rest Ne562b6199afc46caad734b5eb8752b65
110 N2d54266569f04ec78dc5f55c7b431249 rdf:first sg:person.01264414106.95
111 rdf:rest rdf:nil
112 N3461dc90e6ca4605a53f29fba104931a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Holistic Health
114 rdf:type schema:DefinedTerm
115 N4ba3a408f1a44d21a684f7919cdde320 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Food, Fortified
117 rdf:type schema:DefinedTerm
118 N4e6e679a73c14c219ef2d7fdea87d799 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Nutrition Assessment
120 rdf:type schema:DefinedTerm
121 N61a21b5a4dcd42049f2de2f974631ed1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Seasons
123 rdf:type schema:DefinedTerm
124 N6d07da8d36a84f7fa60b5e7a3d008855 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Vitamin D
126 rdf:type schema:DefinedTerm
127 N6d8f1c87f3704ca2b324476d1e580f15 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Middle Aged
129 rdf:type schema:DefinedTerm
130 N783ee42526464d4cba98da46d0c385f7 schema:name Springer Nature - SN SciGraph project
131 rdf:type schema:Organization
132 N7bcc1f4561514044b998e896bea02e50 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Life Style
134 rdf:type schema:DefinedTerm
135 N838fe790b8c14ca9b89f9a8ca5f0d8f7 schema:name dimensions_id
136 schema:value pub.1036858365
137 rdf:type schema:PropertyValue
138 N843bc8337d0441eb89045f35e1d88c5f schema:name readcube_id
139 schema:value af945013e39b015589ba9152364f307f8a57f904a5128a6e9ed14305cb633f32
140 rdf:type schema:PropertyValue
141 N86cd5622cfc441a4ad453db89c433ada schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Calcium, Dietary
143 rdf:type schema:DefinedTerm
144 N97afe470008f42d0be1853993b5f880a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Dairy Products
146 rdf:type schema:DefinedTerm
147 N9a57d4b6709f44b2bee069627e2c93e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Greece
149 rdf:type schema:DefinedTerm
150 N9d0dd7c06d6441eea2ec0c5ced9035d4 rdf:first sg:person.0733537100.43
151 rdf:rest N2d54266569f04ec78dc5f55c7b431249
152 N9db0928c949e439cab7d5cd9c25ce7bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Aged
154 rdf:type schema:DefinedTerm
155 N9e8eef106fd749c898d71b75d03c8a5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Bone and Bones
157 rdf:type schema:DefinedTerm
158 Na34d31cdb8584a30925cd2ee2ea6cfec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Energy Intake
160 rdf:type schema:DefinedTerm
161 Nb7eee512c0304d4d81c9d47a56e181dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name RANK Ligand
163 rdf:type schema:DefinedTerm
164 Nbb3780fec96a42fe94493b9daef42b58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Follow-Up Studies
166 rdf:type schema:DefinedTerm
167 Nbf608e2aa76142b8b2bd0bdb2a9602ef schema:name doi
168 schema:value 10.1007/s00394-010-0142-7
169 rdf:type schema:PropertyValue
170 Ncd4b393c32c4433f9942241bf6bdcc81 schema:issueNumber 5
171 rdf:type schema:PublicationIssue
172 Ne562b6199afc46caad734b5eb8752b65 rdf:first sg:person.01016755660.57
173 rdf:rest N9d0dd7c06d6441eea2ec0c5ced9035d4
174 Ne84d2c23cc604ccd9a0bcfe683a87b22 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Dietary Supplements
176 rdf:type schema:DefinedTerm
177 Nf477e56d514c455d92280b9f6ba085f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Postmenopause
179 rdf:type schema:DefinedTerm
180 Nf57e70064c69445c94a650c095f50128 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Vitamins
182 rdf:type schema:DefinedTerm
183 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
184 schema:name Medical and Health Sciences
185 rdf:type schema:DefinedTerm
186 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
187 schema:name Clinical Sciences
188 rdf:type schema:DefinedTerm
189 sg:journal.1294989 schema:issn 1435-1293
190 1436-6207
191 schema:name European Journal of Nutrition
192 rdf:type schema:Periodical
193 sg:person.01016755660.57 schema:affiliation https://www.grid.ac/institutes/grid.15823.3d
194 schema:familyName Moschonis
195 schema:givenName George
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016755660.57
197 rdf:type schema:Person
198 sg:person.01125531320.59 schema:affiliation https://www.grid.ac/institutes/grid.15823.3d
199 schema:familyName Tenta
200 schema:givenName Roxane
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125531320.59
202 rdf:type schema:Person
203 sg:person.01264414106.95 schema:affiliation https://www.grid.ac/institutes/grid.15823.3d
204 schema:familyName Manios
205 schema:givenName Yannis
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264414106.95
207 rdf:type schema:Person
208 sg:person.0733537100.43 schema:affiliation https://www.grid.ac/institutes/grid.5216.0
209 schema:familyName Koutsilieris
210 schema:givenName Michael
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733537100.43
212 rdf:type schema:Person
213 sg:pub.10.1007/s00198-003-1448-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024758573
214 https://doi.org/10.1007/s00198-003-1448-6
215 rdf:type schema:CreativeWork
216 sg:pub.10.1007/s001980050062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025292854
217 https://doi.org/10.1007/s001980050062
218 rdf:type schema:CreativeWork
219 sg:pub.10.1007/s001980070005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024411521
220 https://doi.org/10.1007/s001980070005
221 rdf:type schema:CreativeWork
222 sg:pub.10.1186/1471-2458-4-66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053174238
223 https://doi.org/10.1186/1471-2458-4-66
224 rdf:type schema:CreativeWork
225 https://app.dimensions.ai/details/publication/pub.1077408716 schema:CreativeWork
226 https://app.dimensions.ai/details/publication/pub.1082581793 schema:CreativeWork
227 https://doi.org/10.1001/jama.292.4.490 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039057059
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/j.autrev.2010.06.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034863625
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/j.bbcan.2004.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017453309
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/j.dinthera.2005.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021322501
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/s0002-8223(99)00302-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039240934
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/s0002-9343(99)80310-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016498352
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/s8756-3282(02)00853-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003446942
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1017/s000711451000019x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015063926
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1056/nejm199009273231305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008147081
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1056/nejm199709043371003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047469735
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1093/ajcn/73.2.288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074750794
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1093/ajcn/77.1.204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075208306
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1093/ajcn/81.5.1232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077050123
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1093/ajcn/86.3.781 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077478546
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1093/ajcn/87.6.1952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077659037
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1093/jn/135.2.310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076998587
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1123/pes.9.2.159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062434967
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1136/bmj.c3691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041990973
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1185/03007991003659814 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013955274
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1196/annals.1365.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045455492
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1210/jc.83.11.3817 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064299918
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1359/jbmr.080201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016075536
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1359/jbmr.1998.13.2.168 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050506060
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1359/jbmr.2000.15.11.2276 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025477338
274 rdf:type schema:CreativeWork
275 https://doi.org/10.4158/ep.9.6.544 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015983244
276 rdf:type schema:CreativeWork
277 https://doi.org/10.7326/0003-4819-128-10-199805150-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073701846
278 rdf:type schema:CreativeWork
279 https://doi.org/10.7326/0003-4819-152-5-201003020-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073711386
280 rdf:type schema:CreativeWork
281 https://www.grid.ac/institutes/grid.15823.3d schema:alternateName Harokopio University
282 schema:name Department of Nutrition and Dietetics, Harokopio University, 70, El.Venizelou Ave, 176 71 Kallithea, Athens, Greece
283 rdf:type schema:Organization
284 https://www.grid.ac/institutes/grid.5216.0 schema:alternateName National and Kapodistrian University of Athens
285 schema:name Department of Experimental Physiology, Medical School, University of Athens, 75 Micras Asias, 115 27, Goudi-Athens, Greece
286 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...