Immunrekonstitutionssyndrom des Dünndarms bei einer immunsupprimierten Patientin mit systemischem Lupus erythematodes und nichttuberkulöser Mykobakteriose View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-07

AUTHORS

S. Daum, V. Moos, C. Loddenkemper, C. Schürmann, E. Märker-Hermann, H. Stein, M. Zeitz, T. Schneider

ABSTRACT

An overwhelming immune reaction resulting in granulomatous inflammation after infection with opportunistic pathogens is termed immune reconstitution inflammatory syndrome (IRIS). It has mainly been described in patients with human immunodeficiency virus (HIV) infection on highly active antiretroviral therapy (HAART) who show a significant increase of low CD4 T cells (initially <50/microl). IRIS may lead to organ damage and differential diagnosis is often difficult. We report the case of a 38-year-old female patient who developed a Mycobacteria genavense infection of the liver and the bowel after several immunosuppressive therapies for systemic lupus erythematosus. CD4 T cell counts as low as 17/microl were found and immunosuppressive therapy was stopped. Despite several courses of antibiotic treatment and rising CD4 T cell counts, severe malabsorption persisted. Upper endoscopy revealed a continuous inflammation with pseudopolyps of the small bowel and histologically, a granulomatous infiltrate was detected. After exclusion of a persisting infection by Mycobacteria genavense, IRIS of the small bowel was suspected and treatment with prednisolone was started. The clinical and histological picture improved significantly, the number of CD25(+)CD4(+) cells decreased in the lamina propria of the duodenum under treatment with prednisolone and Foxp3+ regulatory T cells (Treg) accumulated around granulomas. This case shows that IRIS is not restricted to HIV patients but may also occur in otherwise immunosuppressed patients. Due to different treatment strategies, distinguishing IRIS from infectious diseases is essential. The role of Treg in IRIS has to be elucidated. More... »

PAGES

277-283

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00393-008-0298-1

DOI

http://dx.doi.org/10.1007/s00393-008-0298-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050120131

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18528698


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enteritis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immune Reconstitution Inflammatory Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunocompromised Host", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intestine, Small", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lupus Erythematosus, Systemic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mycobacterium Infections", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Campus Benjamin Franklin", 
          "id": "https://www.grid.ac/institutes/grid.412753.6", 
          "name": [
            "Medizinische Klinik I, Gastroenterologie, Infektiologie und Rheumatologie, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Daum", 
        "givenName": "S.", 
        "id": "sg:person.01071370063.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071370063.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Benjamin Franklin", 
          "id": "https://www.grid.ac/institutes/grid.412753.6", 
          "name": [
            "Medizinische Klinik I, Gastroenterologie, Infektiologie und Rheumatologie, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moos", 
        "givenName": "V.", 
        "id": "sg:person.01105670727.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105670727.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Charit\u00e9", 
          "id": "https://www.grid.ac/institutes/grid.6363.0", 
          "name": [
            "Institut f\u00fcr Pathologie, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Loddenkemper", 
        "givenName": "C.", 
        "id": "sg:person.01045165647.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045165647.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Benjamin Franklin", 
          "id": "https://www.grid.ac/institutes/grid.412753.6", 
          "name": [
            "Medizinische Klinik I, Gastroenterologie, Infektiologie und Rheumatologie, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sch\u00fcrmann", 
        "givenName": "C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Helios Dr. Horst Schmidt Kliniken Wiesbaden", 
          "id": "https://www.grid.ac/institutes/grid.491861.3", 
          "name": [
            "Medizinsche Klinik IV, Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "M\u00e4rker-Hermann", 
        "givenName": "E.", 
        "id": "sg:person.01036662032.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036662032.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Charit\u00e9", 
          "id": "https://www.grid.ac/institutes/grid.6363.0", 
          "name": [
            "Institut f\u00fcr Pathologie, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stein", 
        "givenName": "H.", 
        "id": "sg:person.012524107752.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012524107752.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Benjamin Franklin", 
          "id": "https://www.grid.ac/institutes/grid.412753.6", 
          "name": [
            "Medizinische Klinik I, Gastroenterologie, Infektiologie und Rheumatologie, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zeitz", 
        "givenName": "M.", 
        "id": "sg:person.0754646467.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754646467.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Benjamin Franklin", 
          "id": "https://www.grid.ac/institutes/grid.412753.6", 
          "name": [
            "Medizinische Klinik I, Gastroenterologie, Infektiologie und Rheumatologie, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schneider", 
        "givenName": "T.", 
        "id": "sg:person.01326233415.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326233415.81"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1084/jem.20050648", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013009665"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2249.1994.tb07014.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020493466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2249.1994.tb07014.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020493466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3062.2007.00285.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027919451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cgh.2007.04.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029798372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ni1178", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034654370", 
          "https://doi.org/10.1038/ni1178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ni1178", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034654370", 
          "https://doi.org/10.1038/ni1178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ni1178", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034654370", 
          "https://doi.org/10.1038/ni1178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dki444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037694795"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10350-004-6339-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045048433", 
          "https://doi.org/10.1007/s10350-004-6339-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/s10350-004-6339-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045048433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1464-2662.2001.00096.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045705015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(92)90397-l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046908059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-133-6-200009190-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073704372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-133-7-200010030-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073704402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077092981", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082133245", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-07", 
    "datePublishedReg": "2008-07-01", 
    "description": "An overwhelming immune reaction resulting in granulomatous inflammation after infection with opportunistic pathogens is termed immune reconstitution inflammatory syndrome (IRIS). It has mainly been described in patients with human immunodeficiency virus (HIV) infection on highly active antiretroviral therapy (HAART) who show a significant increase of low CD4 T cells (initially <50/microl). IRIS may lead to organ damage and differential diagnosis is often difficult. We report the case of a 38-year-old female patient who developed a Mycobacteria genavense infection of the liver and the bowel after several immunosuppressive therapies for systemic lupus erythematosus. CD4 T cell counts as low as 17/microl were found and immunosuppressive therapy was stopped. Despite several courses of antibiotic treatment and rising CD4 T cell counts, severe malabsorption persisted. Upper endoscopy revealed a continuous inflammation with pseudopolyps of the small bowel and histologically, a granulomatous infiltrate was detected. After exclusion of a persisting infection by Mycobacteria genavense, IRIS of the small bowel was suspected and treatment with prednisolone was started. The clinical and histological picture improved significantly, the number of CD25(+)CD4(+) cells decreased in the lamina propria of the duodenum under treatment with prednisolone and Foxp3+ regulatory T cells (Treg) accumulated around granulomas. This case shows that IRIS is not restricted to HIV patients but may also occur in otherwise immunosuppressed patients. Due to different treatment strategies, distinguishing IRIS from infectious diseases is essential. The role of Treg in IRIS has to be elucidated.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00393-008-0298-1", 
    "inLanguage": [
      "de"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1019345", 
        "issn": [
          "0340-1855", 
          "1435-1250"
        ], 
        "name": "Zeitschrift f\u00fcr Rheumatologie", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "67"
      }
    ], 
    "name": "Immunrekonstitutionssyndrom des D\u00fcnndarms bei einer immunsupprimierten Patientin mit systemischem Lupus erythematodes und nichttuberkul\u00f6ser Mykobakteriose", 
    "pagination": "277-283", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "eec1e9274dc9245bf5589b1018bb4e471b37ebf2158e0189509b52e1bc95e425"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18528698"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0414162"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00393-008-0298-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050120131"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00393-008-0298-1", 
      "https://app.dimensions.ai/details/publication/pub.1050120131"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:32", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13102_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00393-008-0298-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00393-008-0298-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00393-008-0298-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00393-008-0298-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00393-008-0298-1'


 

This table displays all metadata directly associated to this object as RDF triples.

201 TRIPLES      21 PREDICATES      52 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00393-008-0298-1 schema:about N0a2de6e428cf4ada86593da612b539ce
2 N3087aa28c7894f27af713d9fa6f5d515
3 N48c6cea19d0f4eac8b95865a70bafa18
4 N4ba24d2e04cf4d9aa2878b1c65627d47
5 N509f333d1b564ce38c65569f4bf333e6
6 N904b013b8e3541b5b8c9c3f48531ada5
7 Nac39f176a3be49e58980108a39bb469e
8 Nca8444660e65430992eb03dc79283e01
9 Neca727e2cb3341198c3ecc4b7c851ff2
10 anzsrc-for:11
11 anzsrc-for:1107
12 schema:author N81bae17e9d554890b786c99a0fd4bfff
13 schema:citation sg:pub.10.1007/s10350-004-6339-1
14 sg:pub.10.1038/ni1178
15 https://app.dimensions.ai/details/publication/pub.1077092981
16 https://app.dimensions.ai/details/publication/pub.1082133245
17 https://doi.org/10.1007/s10350-004-6339-1
18 https://doi.org/10.1016/0140-6736(92)90397-l
19 https://doi.org/10.1016/j.cgh.2007.04.020
20 https://doi.org/10.1046/j.1464-2662.2001.00096.x
21 https://doi.org/10.1084/jem.20050648
22 https://doi.org/10.1093/jac/dki444
23 https://doi.org/10.1111/j.1365-2249.1994.tb07014.x
24 https://doi.org/10.1111/j.1399-3062.2007.00285.x
25 https://doi.org/10.7326/0003-4819-133-6-200009190-00013
26 https://doi.org/10.7326/0003-4819-133-7-200010030-00008
27 schema:datePublished 2008-07
28 schema:datePublishedReg 2008-07-01
29 schema:description An overwhelming immune reaction resulting in granulomatous inflammation after infection with opportunistic pathogens is termed immune reconstitution inflammatory syndrome (IRIS). It has mainly been described in patients with human immunodeficiency virus (HIV) infection on highly active antiretroviral therapy (HAART) who show a significant increase of low CD4 T cells (initially <50/microl). IRIS may lead to organ damage and differential diagnosis is often difficult. We report the case of a 38-year-old female patient who developed a Mycobacteria genavense infection of the liver and the bowel after several immunosuppressive therapies for systemic lupus erythematosus. CD4 T cell counts as low as 17/microl were found and immunosuppressive therapy was stopped. Despite several courses of antibiotic treatment and rising CD4 T cell counts, severe malabsorption persisted. Upper endoscopy revealed a continuous inflammation with pseudopolyps of the small bowel and histologically, a granulomatous infiltrate was detected. After exclusion of a persisting infection by Mycobacteria genavense, IRIS of the small bowel was suspected and treatment with prednisolone was started. The clinical and histological picture improved significantly, the number of CD25(+)CD4(+) cells decreased in the lamina propria of the duodenum under treatment with prednisolone and Foxp3+ regulatory T cells (Treg) accumulated around granulomas. This case shows that IRIS is not restricted to HIV patients but may also occur in otherwise immunosuppressed patients. Due to different treatment strategies, distinguishing IRIS from infectious diseases is essential. The role of Treg in IRIS has to be elucidated.
30 schema:genre research_article
31 schema:inLanguage de
32 schema:isAccessibleForFree false
33 schema:isPartOf N2516c37696c64c3faf1a0fcfbfcd807f
34 Nbf8d958dfba14542ad0a79aac88c9125
35 sg:journal.1019345
36 schema:name Immunrekonstitutionssyndrom des Dünndarms bei einer immunsupprimierten Patientin mit systemischem Lupus erythematodes und nichttuberkulöser Mykobakteriose
37 schema:pagination 277-283
38 schema:productId N99ff1c31b0274bffb3156011717ce9cb
39 N9b9cd783e3c8441bb2323d88eca84fe8
40 Nb288f90f31c54e60a62e030250ac0ffd
41 Nc948f7e401c74f0bba0ab49bb5bd092f
42 Nefaae92d2e1c4d81ac4946d33797062a
43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050120131
44 https://doi.org/10.1007/s00393-008-0298-1
45 schema:sdDatePublished 2019-04-11T14:32
46 schema:sdLicense https://scigraph.springernature.com/explorer/license/
47 schema:sdPublisher N811bf74e47ca4a3bb06c50209f4c8617
48 schema:url http://link.springer.com/10.1007%2Fs00393-008-0298-1
49 sgo:license sg:explorer/license/
50 sgo:sdDataset articles
51 rdf:type schema:ScholarlyArticle
52 N0a2de6e428cf4ada86593da612b539ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
53 schema:name Mycobacterium Infections
54 rdf:type schema:DefinedTerm
55 N2516c37696c64c3faf1a0fcfbfcd807f schema:issueNumber 4
56 rdf:type schema:PublicationIssue
57 N3087aa28c7894f27af713d9fa6f5d515 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
58 schema:name Humans
59 rdf:type schema:DefinedTerm
60 N475cc4fd576c4d1b9dff685aed3952ea rdf:first sg:person.012524107752.45
61 rdf:rest Nad9c8c2e5d734a63b7ba3fcf8eebe650
62 N48c6cea19d0f4eac8b95865a70bafa18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
63 schema:name Enteritis
64 rdf:type schema:DefinedTerm
65 N4ba24d2e04cf4d9aa2878b1c65627d47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
66 schema:name Female
67 rdf:type schema:DefinedTerm
68 N509f333d1b564ce38c65569f4bf333e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Immune Reconstitution Inflammatory Syndrome
70 rdf:type schema:DefinedTerm
71 N811bf74e47ca4a3bb06c50209f4c8617 schema:name Springer Nature - SN SciGraph project
72 rdf:type schema:Organization
73 N81bae17e9d554890b786c99a0fd4bfff rdf:first sg:person.01071370063.84
74 rdf:rest Nf1270efd71804f5aa4402159927c732d
75 N840516070a9c4ce799f0e67077fb1f0e rdf:first sg:person.01036662032.33
76 rdf:rest N475cc4fd576c4d1b9dff685aed3952ea
77 N8768333b5d9c4466a08c43091fec2e8b rdf:first N92eaef29a33a4431ac8ee38be0346327
78 rdf:rest N840516070a9c4ce799f0e67077fb1f0e
79 N904b013b8e3541b5b8c9c3f48531ada5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Intestine, Small
81 rdf:type schema:DefinedTerm
82 N92eaef29a33a4431ac8ee38be0346327 schema:affiliation https://www.grid.ac/institutes/grid.412753.6
83 schema:familyName Schürmann
84 schema:givenName C.
85 rdf:type schema:Person
86 N99ff1c31b0274bffb3156011717ce9cb schema:name readcube_id
87 schema:value eec1e9274dc9245bf5589b1018bb4e471b37ebf2158e0189509b52e1bc95e425
88 rdf:type schema:PropertyValue
89 N9b9cd783e3c8441bb2323d88eca84fe8 schema:name dimensions_id
90 schema:value pub.1050120131
91 rdf:type schema:PropertyValue
92 Nac39f176a3be49e58980108a39bb469e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Adult
94 rdf:type schema:DefinedTerm
95 Nad9c8c2e5d734a63b7ba3fcf8eebe650 rdf:first sg:person.0754646467.02
96 rdf:rest Ncb8a47501d2549fb80b22dd400fe3352
97 Nb209a31d171f4198ac82a9e2ea287766 rdf:first sg:person.01045165647.42
98 rdf:rest N8768333b5d9c4466a08c43091fec2e8b
99 Nb288f90f31c54e60a62e030250ac0ffd schema:name pubmed_id
100 schema:value 18528698
101 rdf:type schema:PropertyValue
102 Nbf8d958dfba14542ad0a79aac88c9125 schema:volumeNumber 67
103 rdf:type schema:PublicationVolume
104 Nc948f7e401c74f0bba0ab49bb5bd092f schema:name doi
105 schema:value 10.1007/s00393-008-0298-1
106 rdf:type schema:PropertyValue
107 Nca8444660e65430992eb03dc79283e01 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Lupus Erythematosus, Systemic
109 rdf:type schema:DefinedTerm
110 Ncb8a47501d2549fb80b22dd400fe3352 rdf:first sg:person.01326233415.81
111 rdf:rest rdf:nil
112 Neca727e2cb3341198c3ecc4b7c851ff2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Immunocompromised Host
114 rdf:type schema:DefinedTerm
115 Nefaae92d2e1c4d81ac4946d33797062a schema:name nlm_unique_id
116 schema:value 0414162
117 rdf:type schema:PropertyValue
118 Nf1270efd71804f5aa4402159927c732d rdf:first sg:person.01105670727.26
119 rdf:rest Nb209a31d171f4198ac82a9e2ea287766
120 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
121 schema:name Medical and Health Sciences
122 rdf:type schema:DefinedTerm
123 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
124 schema:name Immunology
125 rdf:type schema:DefinedTerm
126 sg:journal.1019345 schema:issn 0340-1855
127 1435-1250
128 schema:name Zeitschrift für Rheumatologie
129 rdf:type schema:Periodical
130 sg:person.01036662032.33 schema:affiliation https://www.grid.ac/institutes/grid.491861.3
131 schema:familyName Märker-Hermann
132 schema:givenName E.
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036662032.33
134 rdf:type schema:Person
135 sg:person.01045165647.42 schema:affiliation https://www.grid.ac/institutes/grid.6363.0
136 schema:familyName Loddenkemper
137 schema:givenName C.
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045165647.42
139 rdf:type schema:Person
140 sg:person.01071370063.84 schema:affiliation https://www.grid.ac/institutes/grid.412753.6
141 schema:familyName Daum
142 schema:givenName S.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071370063.84
144 rdf:type schema:Person
145 sg:person.01105670727.26 schema:affiliation https://www.grid.ac/institutes/grid.412753.6
146 schema:familyName Moos
147 schema:givenName V.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105670727.26
149 rdf:type schema:Person
150 sg:person.012524107752.45 schema:affiliation https://www.grid.ac/institutes/grid.6363.0
151 schema:familyName Stein
152 schema:givenName H.
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012524107752.45
154 rdf:type schema:Person
155 sg:person.01326233415.81 schema:affiliation https://www.grid.ac/institutes/grid.412753.6
156 schema:familyName Schneider
157 schema:givenName T.
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326233415.81
159 rdf:type schema:Person
160 sg:person.0754646467.02 schema:affiliation https://www.grid.ac/institutes/grid.412753.6
161 schema:familyName Zeitz
162 schema:givenName M.
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754646467.02
164 rdf:type schema:Person
165 sg:pub.10.1007/s10350-004-6339-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045048433
166 https://doi.org/10.1007/s10350-004-6339-1
167 rdf:type schema:CreativeWork
168 sg:pub.10.1038/ni1178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034654370
169 https://doi.org/10.1038/ni1178
170 rdf:type schema:CreativeWork
171 https://app.dimensions.ai/details/publication/pub.1077092981 schema:CreativeWork
172 https://app.dimensions.ai/details/publication/pub.1082133245 schema:CreativeWork
173 https://doi.org/10.1007/s10350-004-6339-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045048433
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/0140-6736(92)90397-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1046908059
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/j.cgh.2007.04.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029798372
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1046/j.1464-2662.2001.00096.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1045705015
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1084/jem.20050648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013009665
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1093/jac/dki444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037694795
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1111/j.1365-2249.1994.tb07014.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020493466
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1111/j.1399-3062.2007.00285.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027919451
188 rdf:type schema:CreativeWork
189 https://doi.org/10.7326/0003-4819-133-6-200009190-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073704372
190 rdf:type schema:CreativeWork
191 https://doi.org/10.7326/0003-4819-133-7-200010030-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073704402
192 rdf:type schema:CreativeWork
193 https://www.grid.ac/institutes/grid.412753.6 schema:alternateName Campus Benjamin Franklin
194 schema:name Medizinische Klinik I, Gastroenterologie, Infektiologie und Rheumatologie, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, 12200, Berlin, Deutschland
195 rdf:type schema:Organization
196 https://www.grid.ac/institutes/grid.491861.3 schema:alternateName Helios Dr. Horst Schmidt Kliniken Wiesbaden
197 schema:name Medizinsche Klinik IV, Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Deutschland
198 rdf:type schema:Organization
199 https://www.grid.ac/institutes/grid.6363.0 schema:alternateName Charité
200 schema:name Institut für Pathologie, Charité-Universitätsmedizin Berlin, Berlin, Deutschland
201 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...