Associations between kidney function and outcomes of comprehensive cardiac rehabilitation in patients with heart failure View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-05-31

AUTHORS

Nobuaki Hamazaki, Kentaro Kamiya, Shohei Yamamoto, Kohei Nozaki, Takafumi Ichikawa, Ryota Matsuzawa, Masashi Yamashita, Shota Uchida, Emi Maekawa, Kentaro Meguro, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Junya Ako

ABSTRACT

AimsTo investigate the impact of baseline kidney function on outcomes following comprehensive cardiac rehabilitation (CR) in patients with heart failure (HF).MethodsWe reviewed a total of 3,727 patients who were admitted for HF treatment. Estimated glomerular filtration rate (eGFR), quadriceps strength (QS), and 6-min walk distance (6MWD) were measured at hospital discharge as a baseline and 5 months thereafter in participants of outpatient comprehensive CR. The association between outpatient CR participation and all-cause events was evaluated using propensity score-matched analysis in subgroups across eGFR stages. The changes in QS and 6MWD following 5-month CR were compared between eGFR stages.ResultsOut of the studied patients, 1585 (42.5%) participated in outpatient CR. After propensity matching for clinical confounders, 2680 patients were included for analysis (pairs of n = 1340 outpatient CR participants and nonparticipants). The participation in outpatient CR was significantly associated with low clinical events in subgroups of eGFR ≥ 60 [hazard ratio (HR): 0.65, 95% confidence interval (CI): 0.51–0.84] and eGFR 45–60 (HR: 0.71, 95% CI: 0.55–0.92), but not in eGFR 30–45 (HR: 0.83, 95% CI: 0.64–1.08) and eGFR < 30 (HR: 0.88, 95% CI: 0.69–1.12). QS and 6MWD were significantly higher after 5-month CR than those at baseline (P < 0.001, respectively), but lower baseline eGFR correlated with lower changes in QS and 6MWD (trend P < 0.001, respectively).ConclusionsAlthough low baseline kidney function attenuates the outcomes of CR, outpatient CR seems to be associated with a better prognosis and positive change in physical function in HF patients with low kidney function.Graphic abstract More... »

PAGES

253-263

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00392-021-01875-2

DOI

http://dx.doi.org/10.1007/s00392-021-01875-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1138480887

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34057614


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ambulatory Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cardiac Rehabilitation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glomerular Filtration Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Failure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Strength", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Propensity Score", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proportional Hazards Models", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rehabilitation Centers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Walk Test", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.508505.d", 
          "name": [
            "Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hamazaki", 
        "givenName": "Nobuaki", 
        "id": "sg:person.01354424531.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354424531.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kamiya", 
        "givenName": "Kentaro", 
        "id": "sg:person.01142562756.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142562756.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.45203.30", 
          "name": [
            "Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan", 
            "Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamamoto", 
        "givenName": "Shohei", 
        "id": "sg:person.010217750644.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010217750644.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.508505.d", 
          "name": [
            "Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nozaki", 
        "givenName": "Kohei", 
        "id": "sg:person.0745247031.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745247031.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.508505.d", 
          "name": [
            "Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ichikawa", 
        "givenName": "Takafumi", 
        "id": "sg:person.012375463653.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012375463653.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physical Therapy, School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan", 
          "id": "http://www.grid.ac/institutes/grid.411532.0", 
          "name": [
            "Department of Physical Therapy, School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsuzawa", 
        "givenName": "Ryota", 
        "id": "sg:person.01045323036.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045323036.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamashita", 
        "givenName": "Masashi", 
        "id": "sg:person.013042105605.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013042105605.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uchida", 
        "givenName": "Shota", 
        "id": "sg:person.011075273077.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011075273077.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maekawa", 
        "givenName": "Emi", 
        "id": "sg:person.01227325761.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227325761.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meguro", 
        "givenName": "Kentaro", 
        "id": "sg:person.016506421751.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016506421751.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamaoka-Tojo", 
        "givenName": "Minako", 
        "id": "sg:person.0630073565.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630073565.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsunaga", 
        "givenName": "Atsuhiko", 
        "id": "sg:person.01347551454.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347551454.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ako", 
        "givenName": "Junya", 
        "id": "sg:person.0744472011.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744472011.56"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/978-981-13-1435-3_18", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107988810", 
          "https://doi.org/10.1007/978-981-13-1435-3_18"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-011-9261-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020837754", 
          "https://doi.org/10.1007/s10741-011-9261-3"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2021-05-31", 
    "datePublishedReg": "2021-05-31", 
    "description": "AimsTo investigate the impact of baseline kidney function on outcomes following comprehensive cardiac rehabilitation (CR) in patients with heart failure (HF).MethodsWe reviewed a total of 3,727 patients who were admitted for HF treatment. Estimated glomerular filtration rate (eGFR), quadriceps strength (QS), and 6-min walk distance (6MWD) were measured at hospital discharge as a baseline and 5\u00a0months thereafter in participants of outpatient comprehensive CR. The association between outpatient CR participation and all-cause events was evaluated using propensity score-matched analysis in subgroups across eGFR stages. The changes in QS and 6MWD following 5-month CR were compared between eGFR stages.ResultsOut of the studied patients, 1585 (42.5%) participated in outpatient CR. After propensity matching for clinical confounders, 2680 patients were included for analysis (pairs of n\u2009=\u20091340 outpatient CR participants and nonparticipants). The participation in outpatient CR was significantly associated with low clinical events in subgroups of eGFR\u2009\u2265\u200960 [hazard ratio (HR): 0.65, 95% confidence interval (CI): 0.51\u20130.84] and eGFR 45\u201360 (HR: 0.71, 95% CI: 0.55\u20130.92), but not in eGFR 30\u201345 (HR: 0.83, 95% CI: 0.64\u20131.08) and eGFR\u2009<\u200930 (HR: 0.88, 95% CI: 0.69\u20131.12). QS and 6MWD were significantly higher after 5-month CR than those at baseline (P\u2009<\u20090.001, respectively), but lower baseline eGFR correlated with lower changes in QS and 6MWD (trend P\u2009<\u20090.001, respectively).ConclusionsAlthough low baseline kidney function attenuates the outcomes of CR, outpatient CR seems to be associated with a better prognosis and positive change in physical function in HF patients with low kidney function.Graphic abstract", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00392-021-01875-2", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1297382", 
        "issn": [
          "1861-0684", 
          "1861-0692"
        ], 
        "name": "Clinical Research in Cardiology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "111"
      }
    ], 
    "keywords": [
      "comprehensive cardiac rehabilitation", 
      "baseline kidney function", 
      "quadriceps strength", 
      "kidney function", 
      "heart failure", 
      "eGFR stage", 
      "cardiac rehabilitation", 
      "comprehensive CR", 
      "lower baseline kidney function", 
      "propensity score-matched analysis", 
      "outpatient CR participation", 
      "lower clinical events", 
      "subgroups of eGFR", 
      "lower baseline eGFR", 
      "lower kidney function", 
      "glomerular filtration rate", 
      "baseline eGFR", 
      "HF patients", 
      "walk distance", 
      "hospital discharge", 
      "clinical confounders", 
      "eGFR 45", 
      "eGFR 30", 
      "CR participation", 
      "better prognosis", 
      "clinical events", 
      "physical function", 
      "filtration rate", 
      "patients", 
      "EGFR", 
      "outcomes", 
      "baseline", 
      "rehabilitation", 
      "subgroups", 
      "association", 
      "HF treatment", 
      "ResultsOut", 
      "positive changes", 
      "failure", 
      "prognosis", 
      "confounders", 
      "MethodsWe", 
      "AimsTo", 
      "months", 
      "lower changes", 
      "treatment", 
      "total", 
      "changes", 
      "events", 
      "function", 
      "participants", 
      "stage", 
      "discharge", 
      "participation", 
      "abstract associations", 
      "cause events", 
      "rate", 
      "analysis", 
      "propensity", 
      "impact", 
      "strength", 
      "distance"
    ], 
    "name": "Associations between kidney function and outcomes of comprehensive cardiac rehabilitation in patients with heart failure", 
    "pagination": "253-263", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1138480887"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00392-021-01875-2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "34057614"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00392-021-01875-2", 
      "https://app.dimensions.ai/details/publication/pub.1138480887"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T16:05", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_889.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00392-021-01875-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00392-021-01875-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00392-021-01875-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00392-021-01875-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00392-021-01875-2'


 

This table displays all metadata directly associated to this object as RDF triples.

297 TRIPLES      21 PREDICATES      106 URIs      96 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00392-021-01875-2 schema:about N09d2525fe2384b6299800442c5a175ac
2 N16907d4e550b4f7195d58e998f64b62e
3 N27ac7b41d5074e648b1ac0944f6c9174
4 N2e54ec7f163547dbbecc51ccfe54718d
5 N3f15efeebf8e4ef6af07d17feda15307
6 N71c4769b536646db8e3a755ec81fea61
7 N7235bce4ab4c40c382459461c042e809
8 N7d2de16b9b394aaaaa80f94dfbc272df
9 N8e09fce4b07848cf8e9a2d4a59c82e30
10 N9ef7a17fa0504971b3b65cbfdb73856a
11 Na18699250966432ba5406a33bb834d9d
12 Nb29b1db69ca447e98f9a11e7bda0e2b4
13 Nbefd3d98629c4de0b9ba0a9232a9df84
14 Ndc4ab5b65c5e417fb5b6d69dd47f8fa3
15 Nef3c6138a8b24984aa045df1603eb373
16 Nf3fe24d5f100468dbb20c25da8274705
17 Nf87790ef870c4fa5990bfe77b8b12514
18 anzsrc-for:11
19 anzsrc-for:1102
20 schema:author N168166f297be42e5adbd40c756fa564d
21 schema:citation sg:pub.10.1007/978-981-13-1435-3_18
22 sg:pub.10.1007/s10741-011-9261-3
23 schema:datePublished 2021-05-31
24 schema:datePublishedReg 2021-05-31
25 schema:description AimsTo investigate the impact of baseline kidney function on outcomes following comprehensive cardiac rehabilitation (CR) in patients with heart failure (HF).MethodsWe reviewed a total of 3,727 patients who were admitted for HF treatment. Estimated glomerular filtration rate (eGFR), quadriceps strength (QS), and 6-min walk distance (6MWD) were measured at hospital discharge as a baseline and 5 months thereafter in participants of outpatient comprehensive CR. The association between outpatient CR participation and all-cause events was evaluated using propensity score-matched analysis in subgroups across eGFR stages. The changes in QS and 6MWD following 5-month CR were compared between eGFR stages.ResultsOut of the studied patients, 1585 (42.5%) participated in outpatient CR. After propensity matching for clinical confounders, 2680 patients were included for analysis (pairs of n = 1340 outpatient CR participants and nonparticipants). The participation in outpatient CR was significantly associated with low clinical events in subgroups of eGFR ≥ 60 [hazard ratio (HR): 0.65, 95% confidence interval (CI): 0.51–0.84] and eGFR 45–60 (HR: 0.71, 95% CI: 0.55–0.92), but not in eGFR 30–45 (HR: 0.83, 95% CI: 0.64–1.08) and eGFR < 30 (HR: 0.88, 95% CI: 0.69–1.12). QS and 6MWD were significantly higher after 5-month CR than those at baseline (P < 0.001, respectively), but lower baseline eGFR correlated with lower changes in QS and 6MWD (trend P < 0.001, respectively).ConclusionsAlthough low baseline kidney function attenuates the outcomes of CR, outpatient CR seems to be associated with a better prognosis and positive change in physical function in HF patients with low kidney function.Graphic abstract
26 schema:genre article
27 schema:isAccessibleForFree false
28 schema:isPartOf N8e0a162652e845e6b7ed7ddb772c1924
29 Nb16088d79aa5461691234b90acaac6be
30 sg:journal.1297382
31 schema:keywords AimsTo
32 CR participation
33 EGFR
34 HF patients
35 HF treatment
36 MethodsWe
37 ResultsOut
38 abstract associations
39 analysis
40 association
41 baseline
42 baseline eGFR
43 baseline kidney function
44 better prognosis
45 cardiac rehabilitation
46 cause events
47 changes
48 clinical confounders
49 clinical events
50 comprehensive CR
51 comprehensive cardiac rehabilitation
52 confounders
53 discharge
54 distance
55 eGFR 30
56 eGFR 45
57 eGFR stage
58 events
59 failure
60 filtration rate
61 function
62 glomerular filtration rate
63 heart failure
64 hospital discharge
65 impact
66 kidney function
67 lower baseline eGFR
68 lower baseline kidney function
69 lower changes
70 lower clinical events
71 lower kidney function
72 months
73 outcomes
74 outpatient CR participation
75 participants
76 participation
77 patients
78 physical function
79 positive changes
80 prognosis
81 propensity
82 propensity score-matched analysis
83 quadriceps strength
84 rate
85 rehabilitation
86 stage
87 strength
88 subgroups
89 subgroups of eGFR
90 total
91 treatment
92 walk distance
93 schema:name Associations between kidney function and outcomes of comprehensive cardiac rehabilitation in patients with heart failure
94 schema:pagination 253-263
95 schema:productId N1ae7b876dba942f0938464ddcea54567
96 N7de8310e90de452d884ec135c4f0ae4b
97 N862e7e0a793e493590941f228cf61187
98 schema:sameAs https://app.dimensions.ai/details/publication/pub.1138480887
99 https://doi.org/10.1007/s00392-021-01875-2
100 schema:sdDatePublished 2022-09-02T16:05
101 schema:sdLicense https://scigraph.springernature.com/explorer/license/
102 schema:sdPublisher N470476f85ea046e9851b9da43946e4e9
103 schema:url https://doi.org/10.1007/s00392-021-01875-2
104 sgo:license sg:explorer/license/
105 sgo:sdDataset articles
106 rdf:type schema:ScholarlyArticle
107 N00452ea336e043b4b6c285a83ebc1b3d rdf:first sg:person.016506421751.89
108 rdf:rest N607104fb0a084fe19f77f43c65e9ec01
109 N09d2525fe2384b6299800442c5a175ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Glomerular Filtration Rate
111 rdf:type schema:DefinedTerm
112 N1052cba7578a42bd8a8b178935bf662d rdf:first sg:person.0745247031.39
113 rdf:rest N3fb6b2267b1245219476e168094af603
114 N168166f297be42e5adbd40c756fa564d rdf:first sg:person.01354424531.30
115 rdf:rest N33c2815b3647463aa0d838842b654859
116 N16907d4e550b4f7195d58e998f64b62e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Cardiac Rehabilitation
118 rdf:type schema:DefinedTerm
119 N1ae7b876dba942f0938464ddcea54567 schema:name pubmed_id
120 schema:value 34057614
121 rdf:type schema:PropertyValue
122 N27ac7b41d5074e648b1ac0944f6c9174 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Proportional Hazards Models
124 rdf:type schema:DefinedTerm
125 N2e54ec7f163547dbbecc51ccfe54718d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Middle Aged
127 rdf:type schema:DefinedTerm
128 N33c2815b3647463aa0d838842b654859 rdf:first sg:person.01142562756.03
129 rdf:rest N9c84798b78d54142bd95c74e27d6c7ab
130 N3f15efeebf8e4ef6af07d17feda15307 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Propensity Score
132 rdf:type schema:DefinedTerm
133 N3f35042d1c904ea9906920da468fd54c rdf:first sg:person.01347551454.97
134 rdf:rest Nbef6a6f4f328439b85b13a4595c431b6
135 N3fb6b2267b1245219476e168094af603 rdf:first sg:person.012375463653.48
136 rdf:rest Nf631fc24b15a42928b268e1bdaa7eae8
137 N470476f85ea046e9851b9da43946e4e9 schema:name Springer Nature - SN SciGraph project
138 rdf:type schema:Organization
139 N607104fb0a084fe19f77f43c65e9ec01 rdf:first sg:person.0630073565.16
140 rdf:rest N3f35042d1c904ea9906920da468fd54c
141 N71c4769b536646db8e3a755ec81fea61 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Muscle Strength
143 rdf:type schema:DefinedTerm
144 N7235bce4ab4c40c382459461c042e809 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Heart Failure
146 rdf:type schema:DefinedTerm
147 N7d2de16b9b394aaaaa80f94dfbc272df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Kidney
149 rdf:type schema:DefinedTerm
150 N7de8310e90de452d884ec135c4f0ae4b schema:name dimensions_id
151 schema:value pub.1138480887
152 rdf:type schema:PropertyValue
153 N862e7e0a793e493590941f228cf61187 schema:name doi
154 schema:value 10.1007/s00392-021-01875-2
155 rdf:type schema:PropertyValue
156 N8bab8f2aa9bc4e228d572d40d87b7123 rdf:first sg:person.013042105605.92
157 rdf:rest N9783a6dd9e8343e999539d2bc4042367
158 N8e09fce4b07848cf8e9a2d4a59c82e30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Female
160 rdf:type schema:DefinedTerm
161 N8e0a162652e845e6b7ed7ddb772c1924 schema:volumeNumber 111
162 rdf:type schema:PublicationVolume
163 N9783a6dd9e8343e999539d2bc4042367 rdf:first sg:person.011075273077.24
164 rdf:rest Na045018c7e45471e89c1fcfe74a20d0c
165 N9c84798b78d54142bd95c74e27d6c7ab rdf:first sg:person.010217750644.16
166 rdf:rest N1052cba7578a42bd8a8b178935bf662d
167 N9ef7a17fa0504971b3b65cbfdb73856a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Rehabilitation Centers
169 rdf:type schema:DefinedTerm
170 Na045018c7e45471e89c1fcfe74a20d0c rdf:first sg:person.01227325761.00
171 rdf:rest N00452ea336e043b4b6c285a83ebc1b3d
172 Na18699250966432ba5406a33bb834d9d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Treatment Outcome
174 rdf:type schema:DefinedTerm
175 Nb16088d79aa5461691234b90acaac6be schema:issueNumber 3
176 rdf:type schema:PublicationIssue
177 Nb29b1db69ca447e98f9a11e7bda0e2b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Male
179 rdf:type schema:DefinedTerm
180 Nbef6a6f4f328439b85b13a4595c431b6 rdf:first sg:person.0744472011.56
181 rdf:rest rdf:nil
182 Nbefd3d98629c4de0b9ba0a9232a9df84 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Walk Test
184 rdf:type schema:DefinedTerm
185 Ndc4ab5b65c5e417fb5b6d69dd47f8fa3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Prognosis
187 rdf:type schema:DefinedTerm
188 Nef3c6138a8b24984aa045df1603eb373 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Aged
190 rdf:type schema:DefinedTerm
191 Nf3fe24d5f100468dbb20c25da8274705 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Humans
193 rdf:type schema:DefinedTerm
194 Nf631fc24b15a42928b268e1bdaa7eae8 rdf:first sg:person.01045323036.24
195 rdf:rest N8bab8f2aa9bc4e228d572d40d87b7123
196 Nf87790ef870c4fa5990bfe77b8b12514 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Ambulatory Care
198 rdf:type schema:DefinedTerm
199 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
200 schema:name Medical and Health Sciences
201 rdf:type schema:DefinedTerm
202 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
203 schema:name Cardiorespiratory Medicine and Haematology
204 rdf:type schema:DefinedTerm
205 sg:journal.1297382 schema:issn 1861-0684
206 1861-0692
207 schema:name Clinical Research in Cardiology
208 schema:publisher Springer Nature
209 rdf:type schema:Periodical
210 sg:person.010217750644.16 schema:affiliation grid-institutes:grid.45203.30
211 schema:familyName Yamamoto
212 schema:givenName Shohei
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010217750644.16
214 rdf:type schema:Person
215 sg:person.01045323036.24 schema:affiliation grid-institutes:grid.411532.0
216 schema:familyName Matsuzawa
217 schema:givenName Ryota
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045323036.24
219 rdf:type schema:Person
220 sg:person.011075273077.24 schema:affiliation grid-institutes:grid.410786.c
221 schema:familyName Uchida
222 schema:givenName Shota
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011075273077.24
224 rdf:type schema:Person
225 sg:person.01142562756.03 schema:affiliation grid-institutes:grid.410786.c
226 schema:familyName Kamiya
227 schema:givenName Kentaro
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142562756.03
229 rdf:type schema:Person
230 sg:person.01227325761.00 schema:affiliation grid-institutes:grid.410786.c
231 schema:familyName Maekawa
232 schema:givenName Emi
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227325761.00
234 rdf:type schema:Person
235 sg:person.012375463653.48 schema:affiliation grid-institutes:grid.508505.d
236 schema:familyName Ichikawa
237 schema:givenName Takafumi
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012375463653.48
239 rdf:type schema:Person
240 sg:person.013042105605.92 schema:affiliation grid-institutes:grid.410786.c
241 schema:familyName Yamashita
242 schema:givenName Masashi
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013042105605.92
244 rdf:type schema:Person
245 sg:person.01347551454.97 schema:affiliation grid-institutes:grid.410786.c
246 schema:familyName Matsunaga
247 schema:givenName Atsuhiko
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347551454.97
249 rdf:type schema:Person
250 sg:person.01354424531.30 schema:affiliation grid-institutes:grid.508505.d
251 schema:familyName Hamazaki
252 schema:givenName Nobuaki
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354424531.30
254 rdf:type schema:Person
255 sg:person.016506421751.89 schema:affiliation grid-institutes:grid.410786.c
256 schema:familyName Meguro
257 schema:givenName Kentaro
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016506421751.89
259 rdf:type schema:Person
260 sg:person.0630073565.16 schema:affiliation grid-institutes:grid.410786.c
261 schema:familyName Yamaoka-Tojo
262 schema:givenName Minako
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630073565.16
264 rdf:type schema:Person
265 sg:person.0744472011.56 schema:affiliation grid-institutes:grid.410786.c
266 schema:familyName Ako
267 schema:givenName Junya
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744472011.56
269 rdf:type schema:Person
270 sg:person.0745247031.39 schema:affiliation grid-institutes:grid.508505.d
271 schema:familyName Nozaki
272 schema:givenName Kohei
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745247031.39
274 rdf:type schema:Person
275 sg:pub.10.1007/978-981-13-1435-3_18 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107988810
276 https://doi.org/10.1007/978-981-13-1435-3_18
277 rdf:type schema:CreativeWork
278 sg:pub.10.1007/s10741-011-9261-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020837754
279 https://doi.org/10.1007/s10741-011-9261-3
280 rdf:type schema:CreativeWork
281 grid-institutes:grid.410786.c schema:alternateName Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan
282 Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
283 Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan
284 schema:name Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan
285 Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
286 Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Sagamihara, Japan
287 rdf:type schema:Organization
288 grid-institutes:grid.411532.0 schema:alternateName Department of Physical Therapy, School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan
289 schema:name Department of Physical Therapy, School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan
290 rdf:type schema:Organization
291 grid-institutes:grid.45203.30 schema:alternateName Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan
292 schema:name Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan
293 Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
294 rdf:type schema:Organization
295 grid-institutes:grid.508505.d schema:alternateName Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan
296 schema:name Department of Rehabilitation, Kitasato University Hospital, 1-15-1 Kitasato, Minami-ku, 252-0375, Sagamihara, Kanagawa, Japan
297 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...