Bromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-03

AUTHORS

Arash Haghikia, Johannes Schwab, Jens Vogel-Claussen, Dominik Berliner, Tobias Pfeffer, Tobias König, Carolin Zwadlo, Valeska Abou Moulig, Annegret Franke, Marziel Schwarzkopf, Philipp Ehlermann, Roman Pfister, Guido Michels, Ralf Westenfeld, Verena Stangl, Uwe Kühl, Edith Podewski, Ingrid Kindermann, Michael Böhm, Karen Sliwa, Denise Hilfiker-Kleiner, Johann Bauersachs

ABSTRACT

BACKGROUND: Right ventricular (RV) dysfunction predicts adverse outcome in peripartum cardiomyopathy (PPCM). We recently demonstrated beneficial effects associated with the prolactin release inhibitor bromocriptine at different doses when added to standard heart failure therapy in PPCM. Here, we evaluated for the first time the therapeutic potential of bromocriptine particularly in PPCM patients with RV involvement. METHODS: In this study, 40 patients with PPCM were included, of whom 24 patients had reduced RV ejection fraction (RVEF < 45%). We examined the effect of short-term (1W: bromocriptine, 2.5 mg, 7 days, n = 10) compared with long-term bromocriptine treatment (8W: 5 mg for 2 weeks followed by 2.5 mg for another 6 weeks, n = 14) in addition to guideline-based heart failure therapy in patients with an initial RVEF < 45% on the following outcomes: (1) change from baseline (Δ delta) in RVEF, (2) change from baseline in left ventricular EF (LVEF), and (3) rate of patients with full LV recovery (LVEF ≥ 50%) and (4) rate of patients with full RV recovery (RVEF ≥ 55%) at 6-month follow-up as assessed by cardiac magnetic resonance imaging. RESULTS: Reduced RVEF at initial presentation was associated with a lower rate of full cardiac recovery at 6-month follow-up (patients with RV dysfunction: 58% vs. patients with normal RV function: 81%; p = 0.027). RVEF increased from 38 ± 7 to 53 ± 11% with a delta-RVEF of + 15 ± 12% in the 1W group, and from 35 ± 9 to 58 ± 7% with a Δ RVEF of + 23 ± 10% in the 8W group (Δ RVEF 1W vs 8W: p = 0.118). LVEF increased from 25 ± 8 to 46 ± 12% with a Δ LVEF of + 21 ± 11% in the 1W group, and from 22 ± 6 to 49 ± 10% with a Δ LVEF of + 27 ± 9% in the 8W group (Δ LVEF 1W vs 8W: p = 0.211). Full LV recovery was present in 50% of the 1W group and in 64% of the 8W group (p = 0.678). Full RV recovery was observed in 40% of the 1W group and in 79% of the 8W group (p = 0.092). CONCLUSIONS: Despite overall worse outcome in patients with RV dysfunction at baseline, bromocriptine treatment in PPCM patients with RV involvement was associated with a high rate of full RV and LV recovery, although no significant differences were observed between the short-term and long-term bromocriptine treatment regime. These findings suggest that bromocriptine in addition to standard heart failure therapy may be also effective in PPCM patients with biventricular impairment. More... »

PAGES

290-297

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00392-018-1355-7

DOI

http://dx.doi.org/10.1007/s00392-018-1355-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106224684

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30121697


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Campus Benjamin Franklin", 
          "id": "https://www.grid.ac/institutes/grid.412753.6", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany", 
            "Department of Cardiology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Haghikia", 
        "givenName": "Arash", 
        "id": "sg:person.01363330311.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363330311.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Universit\u00e4tsklinik f\u00fcr Innere Medizin 8-Schwerpunkt Kardiologie und Institut f\u00fcr Radiologie und Nuklearmedizin, Klinikum N\u00fcrnberg S\u00fcd, Paracelsus Medizinische Privatuniversit\u00e4t N\u00fcrnberg, Breslauer Str. 201, 90471, Nuremberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schwab", 
        "givenName": "Johannes", 
        "id": "sg:person.01205177055.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205177055.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vogel-Claussen", 
        "givenName": "Jens", 
        "id": "sg:person.0624733413.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624733413.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Berliner", 
        "givenName": "Dominik", 
        "id": "sg:person.0771601356.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771601356.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pfeffer", 
        "givenName": "Tobias", 
        "id": "sg:person.015466120665.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015466120665.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "K\u00f6nig", 
        "givenName": "Tobias", 
        "id": "sg:person.01313014757.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313014757.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zwadlo", 
        "givenName": "Carolin", 
        "id": "sg:person.01143054001.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143054001.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moulig", 
        "givenName": "Valeska Abou", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Faculty of Medicine, University Leipzig, Clinical Trial Centre (KKS), ZKS Leipzig, Haertelstr. 16-18, 04103, Leipzig, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Franke", 
        "givenName": "Annegret", 
        "id": "sg:person.01071737731.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071737731.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Faculty of Medicine, University Leipzig, Clinical Trial Centre (KKS), ZKS Leipzig, Haertelstr. 16-18, 04103, Leipzig, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schwarzkopf", 
        "givenName": "Marziel", 
        "id": "sg:person.015340143313.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015340143313.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Cardiology, Angiology, and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ehlermann", 
        "givenName": "Philipp", 
        "id": "sg:person.01367155617.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367155617.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Cologne", 
          "id": "https://www.grid.ac/institutes/grid.6190.e", 
          "name": [
            "Department of Cardiology, Pulmonology, and Vascular Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pfister", 
        "givenName": "Roman", 
        "id": "sg:person.0772324141.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772324141.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Cologne", 
          "id": "https://www.grid.ac/institutes/grid.6190.e", 
          "name": [
            "Department of Cardiology, Pulmonology, and Vascular Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Michels", 
        "givenName": "Guido", 
        "id": "sg:person.0625250130.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625250130.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heinrich Heine University D\u00fcsseldorf", 
          "id": "https://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Department of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Duesseldorf, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Westenfeld", 
        "givenName": "Ralf", 
        "id": "sg:person.01315211442.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315211442.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Charit\u00e9", 
          "id": "https://www.grid.ac/institutes/grid.6363.0", 
          "name": [
            "Department for Cardiology and Angiology, Center for Cardiovascular Research (CCR), Charit\u00e9-Universit\u00e4tsmedizin Berlin, Charit\u00e9platz 1, 10117, Berlin, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stangl", 
        "givenName": "Verena", 
        "id": "sg:person.01074020570.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074020570.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Benjamin Franklin", 
          "id": "https://www.grid.ac/institutes/grid.412753.6", 
          "name": [
            "Department of Cardiology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "K\u00fchl", 
        "givenName": "Uwe", 
        "id": "sg:person.0575616571.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575616571.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Podewski", 
        "givenName": "Edith", 
        "id": "sg:person.01165427040.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165427040.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e4tsklinikum des Saarlandes", 
          "id": "https://www.grid.ac/institutes/grid.411937.9", 
          "name": [
            "Department of Internal Medicine III, University Hospital of the Saarland, 66421, Homburg, Saar, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kindermann", 
        "givenName": "Ingrid", 
        "id": "sg:person.01044304737.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044304737.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e4tsklinikum des Saarlandes", 
          "id": "https://www.grid.ac/institutes/grid.411937.9", 
          "name": [
            "Department of Internal Medicine III, University Hospital of the Saarland, 66421, Homburg, Saar, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "B\u00f6hm", 
        "givenName": "Michael", 
        "id": "sg:person.01252023603.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252023603.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Faculty of Health Sciences, Hatter Institute of Cardiology Research in Africa, 2 Anzio Road, Chris Barnard Building, 4th Floor, Observatory, 7925, Cape Town, South Africa"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sliwa", 
        "givenName": "Karen", 
        "id": "sg:person.0672162263.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672162263.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hilfiker-Kleiner", 
        "givenName": "Denise", 
        "id": "sg:person.0733205436.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733205436.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bauersachs", 
        "givenName": "Johann", 
        "id": "sg:person.01152455105.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152455105.32"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00395-013-0366-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001366388", 
          "https://doi.org/10.1007/s00395-013-0366-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00395-013-0366-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001366388", 
          "https://doi.org/10.1007/s00395-013-0366-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1505517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003750459"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2015.06.1309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007722031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature11040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020361241", 
          "https://doi.org/10.1038/nature11040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ehf2.12059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023629788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-015-0869-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027786200", 
          "https://doi.org/10.1007/s00392-015-0869-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-015-0869-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027786200", 
          "https://doi.org/10.1007/s00392-015-0869-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ejhf.586", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028982443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehv009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029498674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.632208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033713434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2006.12.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038330199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-016-1033-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040987776", 
          "https://doi.org/10.1007/s00392-016-1033-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-016-1033-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040987776", 
          "https://doi.org/10.1007/s00392-016-1033-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/heartjnl-2012-302760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048414306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurjhf/hfq120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049340356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.109.901496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051891328"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.115.002756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063343178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.115.002756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063343178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5603/kp.2016.0141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073039498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5603/kp.2016.0141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073039498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ejhf.780", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084011525"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-017-1090-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084021352", 
          "https://doi.org/10.1007/s00392-017-1090-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-017-1090-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084021352", 
          "https://doi.org/10.1007/s00392-017-1090-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehx355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086902749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamacardio.2017.3574", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092290572"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-03", 
    "datePublishedReg": "2019-03-01", 
    "description": "BACKGROUND: Right ventricular (RV) dysfunction predicts adverse outcome in peripartum cardiomyopathy (PPCM). We recently demonstrated beneficial effects associated with the prolactin release inhibitor bromocriptine at different doses when added to standard heart failure therapy in PPCM. Here, we evaluated for the first time the therapeutic potential of bromocriptine particularly in PPCM patients with RV involvement.\nMETHODS: In this study, 40 patients with PPCM were included, of whom 24 patients had reduced RV ejection fraction (RVEF\u2009<\u200945%). We examined the effect of short-term (1W: bromocriptine, 2.5\u00a0mg, 7\u00a0days, n\u2009=\u200910) compared with long-term bromocriptine treatment (8W: 5\u00a0mg for 2\u00a0weeks followed by 2.5\u00a0mg for another 6\u00a0weeks, n\u2009=\u200914) in addition to guideline-based heart failure therapy in patients with an initial RVEF\u2009<\u200945% on the following outcomes: (1) change from baseline (\u0394 delta) in RVEF, (2) change from baseline in left ventricular EF (LVEF), and (3) rate of patients with full LV recovery (LVEF\u2009\u2265\u200950%) and (4) rate of patients with full RV recovery (RVEF\u2009\u2265\u200955%) at 6-month follow-up as assessed by cardiac magnetic resonance imaging.\nRESULTS: Reduced RVEF at initial presentation was associated with a lower rate of full cardiac recovery at 6-month follow-up (patients with RV dysfunction: 58% vs. patients with normal RV function: 81%; p\u2009=\u20090.027). RVEF increased from 38\u2009\u00b1\u20097 to 53\u2009\u00b1\u200911% with a delta-RVEF of +\u200915\u2009\u00b1\u200912% in the 1W group, and from 35\u2009\u00b1\u20099 to 58\u2009\u00b1\u20097% with a \u0394 RVEF of +\u200923\u2009\u00b1\u200910% in the 8W group (\u0394 RVEF 1W vs 8W: p\u2009=\u20090.118). LVEF increased from 25\u2009\u00b1\u20098 to 46\u2009\u00b1\u200912% with a \u0394 LVEF of +\u200921\u2009\u00b1\u200911% in the 1W group, and from 22\u2009\u00b1\u20096 to 49\u2009\u00b1\u200910% with a \u0394 LVEF of +\u200927\u2009\u00b1\u20099% in the 8W group (\u0394 LVEF 1W vs 8W: p\u2009=\u20090.211). Full LV recovery was present in 50% of the 1W group and in 64% of the 8W group (p\u2009=\u20090.678). Full RV recovery was observed in 40% of the 1W group and in 79% of the 8W group (p\u2009=\u20090.092).\nCONCLUSIONS: Despite overall worse outcome in patients with RV dysfunction at baseline, bromocriptine treatment in PPCM patients with RV involvement was associated with a high rate of full RV and LV recovery, although no significant differences were observed between the short-term and long-term bromocriptine treatment regime. These findings suggest that bromocriptine in addition to standard heart failure therapy may be also effective in PPCM patients with biventricular impairment.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00392-018-1355-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1297382", 
        "issn": [
          "1861-0684", 
          "1861-0692"
        ], 
        "name": "Clinical Research in Cardiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "108"
      }
    ], 
    "name": "Bromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction", 
    "pagination": "290-297", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4811459af2090ce3e75223a290f107da56a05050df0a70cd96c19a1ad445ffce"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30121697"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101264123"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00392-018-1355-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1106224684"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00392-018-1355-7", 
      "https://app.dimensions.ai/details/publication/pub.1106224684"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:20", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78968_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00392-018-1355-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00392-018-1355-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00392-018-1355-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00392-018-1355-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00392-018-1355-7'


 

This table displays all metadata directly associated to this object as RDF triples.

308 TRIPLES      21 PREDICATES      49 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00392-018-1355-7 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N30cdcac1ea244369a47b5cfc98e74d8d
4 schema:citation sg:pub.10.1007/s00392-015-0869-5
5 sg:pub.10.1007/s00392-016-1033-6
6 sg:pub.10.1007/s00392-017-1090-5
7 sg:pub.10.1007/s00395-013-0366-9
8 sg:pub.10.1038/nature11040
9 https://doi.org/10.1001/jamacardio.2017.3574
10 https://doi.org/10.1002/ehf2.12059
11 https://doi.org/10.1002/ejhf.586
12 https://doi.org/10.1002/ejhf.780
13 https://doi.org/10.1016/j.cell.2006.12.036
14 https://doi.org/10.1016/j.jacc.2015.06.1309
15 https://doi.org/10.1056/nejmoa1505517
16 https://doi.org/10.1093/eurheartj/ehv009
17 https://doi.org/10.1093/eurheartj/ehx355
18 https://doi.org/10.1093/eurjhf/hfq120
19 https://doi.org/10.1136/heartjnl-2012-302760
20 https://doi.org/10.1161/circheartfailure.115.002756
21 https://doi.org/10.1161/circulationaha.106.632208
22 https://doi.org/10.1161/circulationaha.109.901496
23 https://doi.org/10.5603/kp.2016.0141
24 schema:datePublished 2019-03
25 schema:datePublishedReg 2019-03-01
26 schema:description BACKGROUND: Right ventricular (RV) dysfunction predicts adverse outcome in peripartum cardiomyopathy (PPCM). We recently demonstrated beneficial effects associated with the prolactin release inhibitor bromocriptine at different doses when added to standard heart failure therapy in PPCM. Here, we evaluated for the first time the therapeutic potential of bromocriptine particularly in PPCM patients with RV involvement. METHODS: In this study, 40 patients with PPCM were included, of whom 24 patients had reduced RV ejection fraction (RVEF < 45%). We examined the effect of short-term (1W: bromocriptine, 2.5 mg, 7 days, n = 10) compared with long-term bromocriptine treatment (8W: 5 mg for 2 weeks followed by 2.5 mg for another 6 weeks, n = 14) in addition to guideline-based heart failure therapy in patients with an initial RVEF < 45% on the following outcomes: (1) change from baseline (Δ delta) in RVEF, (2) change from baseline in left ventricular EF (LVEF), and (3) rate of patients with full LV recovery (LVEF ≥ 50%) and (4) rate of patients with full RV recovery (RVEF ≥ 55%) at 6-month follow-up as assessed by cardiac magnetic resonance imaging. RESULTS: Reduced RVEF at initial presentation was associated with a lower rate of full cardiac recovery at 6-month follow-up (patients with RV dysfunction: 58% vs. patients with normal RV function: 81%; p = 0.027). RVEF increased from 38 ± 7 to 53 ± 11% with a delta-RVEF of + 15 ± 12% in the 1W group, and from 35 ± 9 to 58 ± 7% with a Δ RVEF of + 23 ± 10% in the 8W group (Δ RVEF 1W vs 8W: p = 0.118). LVEF increased from 25 ± 8 to 46 ± 12% with a Δ LVEF of + 21 ± 11% in the 1W group, and from 22 ± 6 to 49 ± 10% with a Δ LVEF of + 27 ± 9% in the 8W group (Δ LVEF 1W vs 8W: p = 0.211). Full LV recovery was present in 50% of the 1W group and in 64% of the 8W group (p = 0.678). Full RV recovery was observed in 40% of the 1W group and in 79% of the 8W group (p = 0.092). CONCLUSIONS: Despite overall worse outcome in patients with RV dysfunction at baseline, bromocriptine treatment in PPCM patients with RV involvement was associated with a high rate of full RV and LV recovery, although no significant differences were observed between the short-term and long-term bromocriptine treatment regime. These findings suggest that bromocriptine in addition to standard heart failure therapy may be also effective in PPCM patients with biventricular impairment.
27 schema:genre research_article
28 schema:inLanguage en
29 schema:isAccessibleForFree true
30 schema:isPartOf N5a1264ebca3e4d4281a1fb49e41760d9
31 N939bde27439a4d9788e23cd309c145c6
32 sg:journal.1297382
33 schema:name Bromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction
34 schema:pagination 290-297
35 schema:productId N3c81c90db77b4d2a9d0229fafbf4cfd2
36 N4b2ce412d523442d8018acd1db98948a
37 N97680cc181b94cf389423609ca473b2f
38 Nbd600be48d774d488c4a8cbe794eb416
39 Nfe84a0cfffc74adfb84247efab72a075
40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106224684
41 https://doi.org/10.1007/s00392-018-1355-7
42 schema:sdDatePublished 2019-04-11T13:20
43 schema:sdLicense https://scigraph.springernature.com/explorer/license/
44 schema:sdPublisher Nb5e4649112134e2ca561d8bb1b2edb5e
45 schema:url https://link.springer.com/10.1007%2Fs00392-018-1355-7
46 sgo:license sg:explorer/license/
47 sgo:sdDataset articles
48 rdf:type schema:ScholarlyArticle
49 N0434810cb5294978849920459c3e7336 schema:name Faculty of Medicine, University Leipzig, Clinical Trial Centre (KKS), ZKS Leipzig, Haertelstr. 16-18, 04103, Leipzig, Germany
50 rdf:type schema:Organization
51 N18a1284c12a347df81e7d8fa38f200c8 rdf:first sg:person.01313014757.24
52 rdf:rest N544ac091827d4962a0f631721270e8c2
53 N19b011efac6e43c5abf3409a5ea59568 rdf:first sg:person.0625250130.25
54 rdf:rest Na5d7e13e37fa44489ffc0cf281e52be4
55 N20ea9d12c656465db747f428f7219738 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
56 schema:familyName Moulig
57 schema:givenName Valeska Abou
58 rdf:type schema:Person
59 N2e9d15b679364118bb3613fd359a0631 schema:name Faculty of Health Sciences, Hatter Institute of Cardiology Research in Africa, 2 Anzio Road, Chris Barnard Building, 4th Floor, Observatory, 7925, Cape Town, South Africa
60 rdf:type schema:Organization
61 N30cdcac1ea244369a47b5cfc98e74d8d rdf:first sg:person.01363330311.29
62 rdf:rest Nab6b85449b884d75b2647a431d6390aa
63 N399b6bac7a9a4977a84c24c5deb54b82 rdf:first sg:person.0575616571.30
64 rdf:rest N7d7e67e029904b6bb61a54391100f76d
65 N3c81c90db77b4d2a9d0229fafbf4cfd2 schema:name pubmed_id
66 schema:value 30121697
67 rdf:type schema:PropertyValue
68 N3e9d3e8864a041e9ba7f59c8c2e9a983 schema:name Faculty of Medicine, University Leipzig, Clinical Trial Centre (KKS), ZKS Leipzig, Haertelstr. 16-18, 04103, Leipzig, Germany
69 rdf:type schema:Organization
70 N455909d271f44bad81374ab1c77fcea8 rdf:first sg:person.0771601356.05
71 rdf:rest N52ad6c4606ac418082168996cb6ba8f2
72 N4709825495e940bb8b643d775a2a0f36 rdf:first sg:person.015340143313.89
73 rdf:rest Nf10ca1e7a0734c099a2b025fa0bf86fc
74 N4b2ce412d523442d8018acd1db98948a schema:name dimensions_id
75 schema:value pub.1106224684
76 rdf:type schema:PropertyValue
77 N4c3ae88f59ba4835bed0727ff963207e rdf:first sg:person.01152455105.32
78 rdf:rest rdf:nil
79 N5097aa44b90544caaaf197114aa9306f rdf:first sg:person.01252023603.69
80 rdf:rest N6112f3bf53694c9d8684f868f9f2f543
81 N52ad6c4606ac418082168996cb6ba8f2 rdf:first sg:person.015466120665.26
82 rdf:rest N18a1284c12a347df81e7d8fa38f200c8
83 N544ac091827d4962a0f631721270e8c2 rdf:first sg:person.01143054001.52
84 rdf:rest Nb23c7e4f3442474eae073fd23d8ef635
85 N5a1264ebca3e4d4281a1fb49e41760d9 schema:volumeNumber 108
86 rdf:type schema:PublicationVolume
87 N6112f3bf53694c9d8684f868f9f2f543 rdf:first sg:person.0672162263.55
88 rdf:rest Ncfe8a4d764874b7ebff1ff03c232fd04
89 N776ec82489c04ea8aa1d8c65eb6fa803 schema:name Universitätsklinik für Innere Medizin 8-Schwerpunkt Kardiologie und Institut für Radiologie und Nuklearmedizin, Klinikum Nürnberg Süd, Paracelsus Medizinische Privatuniversität Nürnberg, Breslauer Str. 201, 90471, Nuremberg, Germany
90 rdf:type schema:Organization
91 N7b54591e9ecb4bc59fb3ec291881b8fb rdf:first sg:person.01044304737.29
92 rdf:rest N5097aa44b90544caaaf197114aa9306f
93 N7c679b3400a44c1dae8a43fc05919c9c rdf:first sg:person.0624733413.95
94 rdf:rest N455909d271f44bad81374ab1c77fcea8
95 N7d7e67e029904b6bb61a54391100f76d rdf:first sg:person.01165427040.73
96 rdf:rest N7b54591e9ecb4bc59fb3ec291881b8fb
97 N8e1670cc9f844fb0a85b47dfe1de7f9d rdf:first sg:person.01071737731.13
98 rdf:rest N4709825495e940bb8b643d775a2a0f36
99 N939bde27439a4d9788e23cd309c145c6 schema:issueNumber 3
100 rdf:type schema:PublicationIssue
101 N97680cc181b94cf389423609ca473b2f schema:name nlm_unique_id
102 schema:value 101264123
103 rdf:type schema:PropertyValue
104 N9d28fd87dd7c4fab93fe458c997f24c4 rdf:first sg:person.0772324141.02
105 rdf:rest N19b011efac6e43c5abf3409a5ea59568
106 Na5d7e13e37fa44489ffc0cf281e52be4 rdf:first sg:person.01315211442.29
107 rdf:rest Nd7305c31d2b84da6a0e387be8b8ead03
108 Nab6b85449b884d75b2647a431d6390aa rdf:first sg:person.01205177055.58
109 rdf:rest N7c679b3400a44c1dae8a43fc05919c9c
110 Nb23c7e4f3442474eae073fd23d8ef635 rdf:first N20ea9d12c656465db747f428f7219738
111 rdf:rest N8e1670cc9f844fb0a85b47dfe1de7f9d
112 Nb5e4649112134e2ca561d8bb1b2edb5e schema:name Springer Nature - SN SciGraph project
113 rdf:type schema:Organization
114 Nbd600be48d774d488c4a8cbe794eb416 schema:name doi
115 schema:value 10.1007/s00392-018-1355-7
116 rdf:type schema:PropertyValue
117 Ncfe8a4d764874b7ebff1ff03c232fd04 rdf:first sg:person.0733205436.86
118 rdf:rest N4c3ae88f59ba4835bed0727ff963207e
119 Nd7305c31d2b84da6a0e387be8b8ead03 rdf:first sg:person.01074020570.21
120 rdf:rest N399b6bac7a9a4977a84c24c5deb54b82
121 Nf10ca1e7a0734c099a2b025fa0bf86fc rdf:first sg:person.01367155617.28
122 rdf:rest N9d28fd87dd7c4fab93fe458c997f24c4
123 Nfe84a0cfffc74adfb84247efab72a075 schema:name readcube_id
124 schema:value 4811459af2090ce3e75223a290f107da56a05050df0a70cd96c19a1ad445ffce
125 rdf:type schema:PropertyValue
126 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
127 schema:name Medical and Health Sciences
128 rdf:type schema:DefinedTerm
129 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
130 schema:name Clinical Sciences
131 rdf:type schema:DefinedTerm
132 sg:journal.1297382 schema:issn 1861-0684
133 1861-0692
134 schema:name Clinical Research in Cardiology
135 rdf:type schema:Periodical
136 sg:person.01044304737.29 schema:affiliation https://www.grid.ac/institutes/grid.411937.9
137 schema:familyName Kindermann
138 schema:givenName Ingrid
139 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044304737.29
140 rdf:type schema:Person
141 sg:person.01071737731.13 schema:affiliation N3e9d3e8864a041e9ba7f59c8c2e9a983
142 schema:familyName Franke
143 schema:givenName Annegret
144 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071737731.13
145 rdf:type schema:Person
146 sg:person.01074020570.21 schema:affiliation https://www.grid.ac/institutes/grid.6363.0
147 schema:familyName Stangl
148 schema:givenName Verena
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074020570.21
150 rdf:type schema:Person
151 sg:person.01143054001.52 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
152 schema:familyName Zwadlo
153 schema:givenName Carolin
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143054001.52
155 rdf:type schema:Person
156 sg:person.01152455105.32 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
157 schema:familyName Bauersachs
158 schema:givenName Johann
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152455105.32
160 rdf:type schema:Person
161 sg:person.01165427040.73 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
162 schema:familyName Podewski
163 schema:givenName Edith
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165427040.73
165 rdf:type schema:Person
166 sg:person.01205177055.58 schema:affiliation N776ec82489c04ea8aa1d8c65eb6fa803
167 schema:familyName Schwab
168 schema:givenName Johannes
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205177055.58
170 rdf:type schema:Person
171 sg:person.01252023603.69 schema:affiliation https://www.grid.ac/institutes/grid.411937.9
172 schema:familyName Böhm
173 schema:givenName Michael
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252023603.69
175 rdf:type schema:Person
176 sg:person.01313014757.24 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
177 schema:familyName König
178 schema:givenName Tobias
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313014757.24
180 rdf:type schema:Person
181 sg:person.01315211442.29 schema:affiliation https://www.grid.ac/institutes/grid.411327.2
182 schema:familyName Westenfeld
183 schema:givenName Ralf
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315211442.29
185 rdf:type schema:Person
186 sg:person.01363330311.29 schema:affiliation https://www.grid.ac/institutes/grid.412753.6
187 schema:familyName Haghikia
188 schema:givenName Arash
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363330311.29
190 rdf:type schema:Person
191 sg:person.01367155617.28 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
192 schema:familyName Ehlermann
193 schema:givenName Philipp
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367155617.28
195 rdf:type schema:Person
196 sg:person.015340143313.89 schema:affiliation N0434810cb5294978849920459c3e7336
197 schema:familyName Schwarzkopf
198 schema:givenName Marziel
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015340143313.89
200 rdf:type schema:Person
201 sg:person.015466120665.26 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
202 schema:familyName Pfeffer
203 schema:givenName Tobias
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015466120665.26
205 rdf:type schema:Person
206 sg:person.0575616571.30 schema:affiliation https://www.grid.ac/institutes/grid.412753.6
207 schema:familyName Kühl
208 schema:givenName Uwe
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575616571.30
210 rdf:type schema:Person
211 sg:person.0624733413.95 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
212 schema:familyName Vogel-Claussen
213 schema:givenName Jens
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624733413.95
215 rdf:type schema:Person
216 sg:person.0625250130.25 schema:affiliation https://www.grid.ac/institutes/grid.6190.e
217 schema:familyName Michels
218 schema:givenName Guido
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625250130.25
220 rdf:type schema:Person
221 sg:person.0672162263.55 schema:affiliation N2e9d15b679364118bb3613fd359a0631
222 schema:familyName Sliwa
223 schema:givenName Karen
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672162263.55
225 rdf:type schema:Person
226 sg:person.0733205436.86 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
227 schema:familyName Hilfiker-Kleiner
228 schema:givenName Denise
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733205436.86
230 rdf:type schema:Person
231 sg:person.0771601356.05 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
232 schema:familyName Berliner
233 schema:givenName Dominik
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771601356.05
235 rdf:type schema:Person
236 sg:person.0772324141.02 schema:affiliation https://www.grid.ac/institutes/grid.6190.e
237 schema:familyName Pfister
238 schema:givenName Roman
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772324141.02
240 rdf:type schema:Person
241 sg:pub.10.1007/s00392-015-0869-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027786200
242 https://doi.org/10.1007/s00392-015-0869-5
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/s00392-016-1033-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040987776
245 https://doi.org/10.1007/s00392-016-1033-6
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/s00392-017-1090-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084021352
248 https://doi.org/10.1007/s00392-017-1090-5
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/s00395-013-0366-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001366388
251 https://doi.org/10.1007/s00395-013-0366-9
252 rdf:type schema:CreativeWork
253 sg:pub.10.1038/nature11040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020361241
254 https://doi.org/10.1038/nature11040
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1001/jamacardio.2017.3574 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092290572
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1002/ehf2.12059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023629788
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1002/ejhf.586 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028982443
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1002/ejhf.780 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084011525
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1016/j.cell.2006.12.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038330199
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1016/j.jacc.2015.06.1309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007722031
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1056/nejmoa1505517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003750459
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1093/eurheartj/ehv009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029498674
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1093/eurheartj/ehx355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086902749
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1093/eurjhf/hfq120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049340356
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1136/heartjnl-2012-302760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048414306
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1161/circheartfailure.115.002756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063343178
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1161/circulationaha.106.632208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033713434
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1161/circulationaha.109.901496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051891328
283 rdf:type schema:CreativeWork
284 https://doi.org/10.5603/kp.2016.0141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073039498
285 rdf:type schema:CreativeWork
286 https://www.grid.ac/institutes/grid.10423.34 schema:alternateName Hannover Medical School
287 schema:name Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
288 Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
289 rdf:type schema:Organization
290 https://www.grid.ac/institutes/grid.411327.2 schema:alternateName Heinrich Heine University Düsseldorf
291 schema:name Department of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Duesseldorf, Germany
292 rdf:type schema:Organization
293 https://www.grid.ac/institutes/grid.411937.9 schema:alternateName Universitätsklinikum des Saarlandes
294 schema:name Department of Internal Medicine III, University Hospital of the Saarland, 66421, Homburg, Saar, Germany
295 rdf:type schema:Organization
296 https://www.grid.ac/institutes/grid.412753.6 schema:alternateName Campus Benjamin Franklin
297 schema:name Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
298 Department of Cardiology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany
299 rdf:type schema:Organization
300 https://www.grid.ac/institutes/grid.6190.e schema:alternateName University of Cologne
301 schema:name Department of Cardiology, Pulmonology, and Vascular Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany
302 rdf:type schema:Organization
303 https://www.grid.ac/institutes/grid.6363.0 schema:alternateName Charité
304 schema:name Department for Cardiology and Angiology, Center for Cardiovascular Research (CCR), Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany
305 rdf:type schema:Organization
306 https://www.grid.ac/institutes/grid.7700.0 schema:alternateName Heidelberg University
307 schema:name Department of Cardiology, Angiology, and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
308 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...