Outcome of elderly undergoing extracorporeal life support in refractory cardiogenic shock View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-01-16

AUTHORS

Suzanne de Waha, Tobias Graf, Steffen Desch, Georg Fuernau, Ingo Eitel, Janine Pöss, Alexander Jobs, Thomas Stiermaier, Jakob Ledwoch, Ariane Wiedau, Philipp Lurz, Gerhard Schuler, Holger Thiele

ABSTRACT

BackgroundThe current study presents data from a real-world cohort of patients with refractory cardiogenic shock (CS) undergoing extracorporeal life support (ECLS) focusing on the comparison of elderly versus younger patients.Methods and resultsOne hundred consecutive patients with refractory CS underwent percutaneous ECLS implantation performed by interventional cardiologists. Follow-up was performed at hospital discharge as well as at a median of 18 months [interquartile range 15–36]. Patients were grouped according to median age (≤60 versus >60 years). ECLS could be weaned in more than half of the cohort (n = 56, 56%) with no differences between the age groups (p = 1.00). Despite similar rates of initial haemodynamic stabilisation, in-hospital mortality was higher in patients >60 years (82% versus 58%, p = 0.02). At mid-term follow-up, only three patients were alive in the group of patients >60 years. This resulted in a mortality rate of 94% in the elderly in comparison with 68% in patients aged ≤60 years (p = 0.001).ConclusionsDespite a high rate of initial successful ECLS weaning, mid-term prognosis of patients with CS undergoing ECLS above the age of 60 years is poor with superior results in patients aged ≤60 years. More... »

PAGES

379-385

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00392-016-1068-8

DOI

http://dx.doi.org/10.1007/s00392-016-1068-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046163247

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28093621


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69 similar rates
70 stabilisation
71 study
72 superior results
73 support
74 weaning
75 years
76 younger patients
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