Coronary artery spasm induced by 5-fluorouracil View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-01

AUTHORS

P. Alter, M. Herzum, J. R. Schaefer, B. Maisch

ABSTRACT

The frequently used chemotherapeutic drug 5-fluorouracil (5-FU) is known to cause angina pectoris and arrhythmias; myocardial infarction and sudden cardiac death could occur. Potential reasons for these phenomena range from toxic/metabolic disturbances to coronary artery spasms. This report shows angiographically proven spasmophilia of the coronary arteries and contributes to the understanding of angina pectoris occurring during treatment with 5-FU. Thus, verapamil type calcium antagonists as well as nitrates should be administered primarily in patients with coronary artery disease and in all patients who had been symptomatic during 5-FU administration in order to prevent further episodes. More... »

PAGES

33-37

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00392-005-0159-8

DOI

http://dx.doi.org/10.1007/s00392-005-0159-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015967767

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15668828


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