Osteoporosis and polypharmacy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-08

AUTHORS

M. Gosch, M. Jeske, C. Kammerlander, T. Roth

ABSTRACT

Osteoporosis is very common in elderly patients. Despite the severe health-related consequences for individual patients and the socioeconomic costs caused by osteoporotic fractures, treatment rates are still low. Due to drug interactions and patient compliance, polypharmacy is often mentioned as a reason for undertreatment. Several drugs have a direct or indirect effect on bone metabolism. The present paper discusses the risk of interactions of anti-osteoporotic drugs (oral and parenteral bisphosphonates, raloxifene, strontium ranelate, teriparatide, and denosumab) with other common medications in elderly patients and their impact on bone metabolism and fracture risk. In summary, the number and risk of drug interactions of all common anti-osteoporotic drugs are small and clinically rather irrelevant. However, patients with a polypharmacy are at a higher risk of fractures and should receive osteoporosis treatment, if indicated. More... »

PAGES

450-454

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00391-012-0374-7

    DOI

    http://dx.doi.org/10.1007/s00391-012-0374-7

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1030748273

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22806642


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