Morphological and functional adaptation of the small intestine after colectomy and ileal pouch-anal anastomosis in rats View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-11-17

AUTHORS

Stefan Willis, Kai Kisielinski, Bernd Klosterhalfen, Volker Schumpelick

ABSTRACT

.Background and aims: This study investigated morphological and functional changes in the small bowel after colectomy and ileal pouch-anal anastomosis (IPAA). Methods and materials: In 15 rats electrolyte, glucose, and water absorption was determined by in vivo single-pass perfusion of the proximal and distal small intestine 15 weeks after IPAA. Afterwards the small intestine was resected for morphometric evaluation. Controls were 15 identically treated rats without operation. Results: IPAA led to a significant increase in the small intestinal diameter and a significant increase in villus length and density, which was more apparent in ileum than in jejunum. Therefore the mucosal surface per unit serosa increased significantly by 59% in the jejunum and by 76% in the ileum. In the pouch there was a significant increase in goblet cell density, crypt depth, and diameter of the muscularis which was not detectable in the segments proximal from the pouch. Due to the increase in mucosal surface there was a significant increase in total glucose and electrolyte absorption in the ileum while absorption rates per unit mucosa were unchanged, with the exception of an increase in mucosal sodium absorption. Jejunal absorption and ileal absorption of water remained unchanged. Conclusion: Adaptation of the small intestine after IPAA leads to colonic metaplasia in the pouch and intestinal hyperplasia proximal from the pouch. The loss of colonic absorption is compensated by the increase in ileal mucosal surface with subsequently elevated electrolyte and glucose absorption. Changes in intestinal permeability may be responsible for additional water depletion, which is compensated by the upregulation of enteric water and sodium absorption. More... »

PAGES

85-91

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s003840100352

DOI

http://dx.doi.org/10.1007/s003840100352

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026244508

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12014426


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adaptation, Physiological", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colonic Pouches", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ileum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intestinal Absorption", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intestinal Mucosa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intestines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Jejunum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Wistar", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany", 
          "id": "http://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Willis", 
        "givenName": "Stefan", 
        "id": "sg:person.01106405176.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106405176.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany", 
          "id": "http://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kisielinski", 
        "givenName": "Kai", 
        "id": "sg:person.01167300426.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167300426.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Pathology, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany", 
          "id": "http://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Institute of Pathology, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klosterhalfen", 
        "givenName": "Bernd", 
        "id": "sg:person.010743050164.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010743050164.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany", 
          "id": "http://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schumpelick", 
        "givenName": "Volker", 
        "id": "sg:person.0617257550.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617257550.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01656599", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039726392", 
          "https://doi.org/10.1007/bf01656599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00337584", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030575298", 
          "https://doi.org/10.1007/bf00337584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01312224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024058813", 
          "https://doi.org/10.1007/bf01312224"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2001-11-17", 
    "datePublishedReg": "2001-11-17", 
    "description": "Abstract.Background and aims: This study investigated morphological and functional changes in the small bowel after colectomy and ileal pouch-anal anastomosis (IPAA). Methods and materials: In 15 rats electrolyte, glucose, and water absorption was determined by in vivo single-pass perfusion of the proximal and distal small intestine 15\u00a0weeks after IPAA. Afterwards the small intestine was resected for morphometric evaluation. Controls were 15 identically treated rats without operation. Results: IPAA led to a significant increase in the small intestinal diameter and a significant increase in villus length and density, which was more apparent in ileum than in jejunum. Therefore the mucosal surface per unit serosa increased significantly by 59% in the jejunum and by 76% in the ileum. In the pouch there was a significant increase in goblet cell density, crypt depth, and diameter of the muscularis which was not detectable in the segments proximal from the pouch. Due to the increase in mucosal surface there was a significant increase in total glucose and electrolyte absorption in the ileum while absorption rates per unit mucosa were unchanged, with the exception of an increase in mucosal sodium absorption. Jejunal absorption and ileal absorption of water remained unchanged. Conclusion: Adaptation of the small intestine after IPAA leads to colonic metaplasia in the pouch and intestinal hyperplasia proximal from the pouch. The loss of colonic absorption is compensated by the increase in ileal mucosal surface with subsequently elevated electrolyte and glucose absorption. Changes in intestinal permeability may be responsible for additional water depletion, which is compensated by the upregulation of enteric water and sodium absorption.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s003840100352", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1096381", 
        "issn": [
          "0179-1958", 
          "1432-1262"
        ], 
        "name": "International Journal of Colorectal Disease", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "17"
      }
    ], 
    "keywords": [
      "pouch-anal anastomosis", 
      "mucosal surfaces", 
      "small intestine", 
      "significant increase", 
      "sodium absorption", 
      "goblet cell density", 
      "single-pass perfusion", 
      "colonic metaplasia", 
      "small bowel", 
      "intestinal diameter", 
      "jejunal absorption", 
      "intestinal permeability", 
      "villus length", 
      "crypt depth", 
      "ileal absorption", 
      "colonic absorption", 
      "glucose absorption", 
      "electrolyte absorption", 
      "morphometric evaluation", 
      "functional changes", 
      "IPAA", 
      "ileum", 
      "rats", 
      "colectomy", 
      "intestine", 
      "anastomosis", 
      "jejunum", 
      "pouch", 
      "functional adaptation", 
      "total glucose", 
      "glucose", 
      "bowel", 
      "cell density", 
      "metaplasia", 
      "mucosa", 
      "perfusion", 
      "muscularis", 
      "serosa", 
      "increase", 
      "weeks", 
      "upregulation", 
      "proximal", 
      "absorption rate", 
      "changes", 
      "depletion", 
      "control", 
      "evaluation", 
      "study", 
      "background", 
      "rate", 
      "loss", 
      "diameter", 
      "adaptation", 
      "absorption", 
      "segments", 
      "exception", 
      "permeability", 
      "length", 
      "method", 
      "density", 
      "materials", 
      "operation", 
      "surface", 
      "water", 
      "depth", 
      "electrolyte", 
      "water depletion", 
      "water absorption"
    ], 
    "name": "Morphological and functional adaptation of the small intestine after colectomy and ileal pouch-anal anastomosis in rats", 
    "pagination": "85-91", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1026244508"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s003840100352"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12014426"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s003840100352", 
      "https://app.dimensions.ai/details/publication/pub.1026244508"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_325.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s003840100352"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s003840100352'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s003840100352'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s003840100352'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s003840100352'


 

This table displays all metadata directly associated to this object as RDF triples.

213 TRIPLES      22 PREDICATES      109 URIs      98 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s003840100352 schema:about N0717911db1f744f4b5bc384164d65749
2 N08057426220846efab4bc4a142c3b6e0
3 N0932ba1f5ff743c19a954e0fec88cedc
4 N0bad0a85c848488fbde52f6fe6fcef27
5 N0dc20e45d5d348e6a1fb8b80fb85ca18
6 N2fca990cf532445dad0dbf4356132a09
7 N9f933b05ed67479d8616b72765ffe11f
8 Na78eb43a2ac24ff59205d0e112002dd5
9 Nbcbe52b05d074e74b8a29f03c8cf0bc2
10 Ne2e86e1012754a51b3792ca78bf31ff9
11 Ne9d42845af8447058431b731eec4edfb
12 Nfdfdaa8293af40919e0761e0cd7c59db
13 anzsrc-for:11
14 anzsrc-for:1103
15 schema:author N350cd653328746188f717d083e06196d
16 schema:citation sg:pub.10.1007/bf00337584
17 sg:pub.10.1007/bf01312224
18 sg:pub.10.1007/bf01656599
19 schema:datePublished 2001-11-17
20 schema:datePublishedReg 2001-11-17
21 schema:description Abstract.Background and aims: This study investigated morphological and functional changes in the small bowel after colectomy and ileal pouch-anal anastomosis (IPAA). Methods and materials: In 15 rats electrolyte, glucose, and water absorption was determined by in vivo single-pass perfusion of the proximal and distal small intestine 15 weeks after IPAA. Afterwards the small intestine was resected for morphometric evaluation. Controls were 15 identically treated rats without operation. Results: IPAA led to a significant increase in the small intestinal diameter and a significant increase in villus length and density, which was more apparent in ileum than in jejunum. Therefore the mucosal surface per unit serosa increased significantly by 59% in the jejunum and by 76% in the ileum. In the pouch there was a significant increase in goblet cell density, crypt depth, and diameter of the muscularis which was not detectable in the segments proximal from the pouch. Due to the increase in mucosal surface there was a significant increase in total glucose and electrolyte absorption in the ileum while absorption rates per unit mucosa were unchanged, with the exception of an increase in mucosal sodium absorption. Jejunal absorption and ileal absorption of water remained unchanged. Conclusion: Adaptation of the small intestine after IPAA leads to colonic metaplasia in the pouch and intestinal hyperplasia proximal from the pouch. The loss of colonic absorption is compensated by the increase in ileal mucosal surface with subsequently elevated electrolyte and glucose absorption. Changes in intestinal permeability may be responsible for additional water depletion, which is compensated by the upregulation of enteric water and sodium absorption.
22 schema:genre article
23 schema:inLanguage en
24 schema:isAccessibleForFree false
25 schema:isPartOf N58de93d21afa416db1622177d37fc0e0
26 N6eb91b9f546e427d858460ecd62afc6f
27 sg:journal.1096381
28 schema:keywords IPAA
29 absorption
30 absorption rate
31 adaptation
32 anastomosis
33 background
34 bowel
35 cell density
36 changes
37 colectomy
38 colonic absorption
39 colonic metaplasia
40 control
41 crypt depth
42 density
43 depletion
44 depth
45 diameter
46 electrolyte
47 electrolyte absorption
48 evaluation
49 exception
50 functional adaptation
51 functional changes
52 glucose
53 glucose absorption
54 goblet cell density
55 ileal absorption
56 ileum
57 increase
58 intestinal diameter
59 intestinal permeability
60 intestine
61 jejunal absorption
62 jejunum
63 length
64 loss
65 materials
66 metaplasia
67 method
68 morphometric evaluation
69 mucosa
70 mucosal surfaces
71 muscularis
72 operation
73 perfusion
74 permeability
75 pouch
76 pouch-anal anastomosis
77 proximal
78 rate
79 rats
80 segments
81 serosa
82 significant increase
83 single-pass perfusion
84 small bowel
85 small intestine
86 sodium absorption
87 study
88 surface
89 total glucose
90 upregulation
91 villus length
92 water
93 water absorption
94 water depletion
95 weeks
96 schema:name Morphological and functional adaptation of the small intestine after colectomy and ileal pouch-anal anastomosis in rats
97 schema:pagination 85-91
98 schema:productId N1c0bd62d94e546b7967d98b7b681d942
99 N7fcb0fc5dcb04f6d8acb7dd4bd705808
100 Nd08e09aa3a014095be6c6cfaf7c26d15
101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026244508
102 https://doi.org/10.1007/s003840100352
103 schema:sdDatePublished 2022-05-20T07:21
104 schema:sdLicense https://scigraph.springernature.com/explorer/license/
105 schema:sdPublisher N4dc463765526429ab1fb5c833ef94cc1
106 schema:url https://doi.org/10.1007/s003840100352
107 sgo:license sg:explorer/license/
108 sgo:sdDataset articles
109 rdf:type schema:ScholarlyArticle
110 N0717911db1f744f4b5bc384164d65749 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Intestinal Mucosa
112 rdf:type schema:DefinedTerm
113 N08057426220846efab4bc4a142c3b6e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Adaptation, Physiological
115 rdf:type schema:DefinedTerm
116 N0932ba1f5ff743c19a954e0fec88cedc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Animals
118 rdf:type schema:DefinedTerm
119 N0acd49420d1b4681acee2e57c0a087fb rdf:first sg:person.010743050164.68
120 rdf:rest Ncaecab045476468cb8b9de3e4a25e84c
121 N0bad0a85c848488fbde52f6fe6fcef27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Male
123 rdf:type schema:DefinedTerm
124 N0dc20e45d5d348e6a1fb8b80fb85ca18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Jejunum
126 rdf:type schema:DefinedTerm
127 N1c0bd62d94e546b7967d98b7b681d942 schema:name doi
128 schema:value 10.1007/s003840100352
129 rdf:type schema:PropertyValue
130 N2fca990cf532445dad0dbf4356132a09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Ileum
132 rdf:type schema:DefinedTerm
133 N350cd653328746188f717d083e06196d rdf:first sg:person.01106405176.67
134 rdf:rest Nef0d6ea13847434cb944951cfed8b8ec
135 N4dc463765526429ab1fb5c833ef94cc1 schema:name Springer Nature - SN SciGraph project
136 rdf:type schema:Organization
137 N58de93d21afa416db1622177d37fc0e0 schema:issueNumber 2
138 rdf:type schema:PublicationIssue
139 N6eb91b9f546e427d858460ecd62afc6f schema:volumeNumber 17
140 rdf:type schema:PublicationVolume
141 N7fcb0fc5dcb04f6d8acb7dd4bd705808 schema:name pubmed_id
142 schema:value 12014426
143 rdf:type schema:PropertyValue
144 N9f933b05ed67479d8616b72765ffe11f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Rats
146 rdf:type schema:DefinedTerm
147 Na78eb43a2ac24ff59205d0e112002dd5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Rats, Wistar
149 rdf:type schema:DefinedTerm
150 Nbcbe52b05d074e74b8a29f03c8cf0bc2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Intestinal Absorption
152 rdf:type schema:DefinedTerm
153 Ncaecab045476468cb8b9de3e4a25e84c rdf:first sg:person.0617257550.39
154 rdf:rest rdf:nil
155 Nd08e09aa3a014095be6c6cfaf7c26d15 schema:name dimensions_id
156 schema:value pub.1026244508
157 rdf:type schema:PropertyValue
158 Ne2e86e1012754a51b3792ca78bf31ff9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Intestines
160 rdf:type schema:DefinedTerm
161 Ne9d42845af8447058431b731eec4edfb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Colonic Pouches
163 rdf:type schema:DefinedTerm
164 Nef0d6ea13847434cb944951cfed8b8ec rdf:first sg:person.01167300426.38
165 rdf:rest N0acd49420d1b4681acee2e57c0a087fb
166 Nfdfdaa8293af40919e0761e0cd7c59db schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Colectomy
168 rdf:type schema:DefinedTerm
169 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
170 schema:name Medical and Health Sciences
171 rdf:type schema:DefinedTerm
172 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
173 schema:name Clinical Sciences
174 rdf:type schema:DefinedTerm
175 sg:journal.1096381 schema:issn 0179-1958
176 1432-1262
177 schema:name International Journal of Colorectal Disease
178 schema:publisher Springer Nature
179 rdf:type schema:Periodical
180 sg:person.010743050164.68 schema:affiliation grid-institutes:grid.1957.a
181 schema:familyName Klosterhalfen
182 schema:givenName Bernd
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010743050164.68
184 rdf:type schema:Person
185 sg:person.01106405176.67 schema:affiliation grid-institutes:grid.1957.a
186 schema:familyName Willis
187 schema:givenName Stefan
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106405176.67
189 rdf:type schema:Person
190 sg:person.01167300426.38 schema:affiliation grid-institutes:grid.1957.a
191 schema:familyName Kisielinski
192 schema:givenName Kai
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167300426.38
194 rdf:type schema:Person
195 sg:person.0617257550.39 schema:affiliation grid-institutes:grid.1957.a
196 schema:familyName Schumpelick
197 schema:givenName Volker
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617257550.39
199 rdf:type schema:Person
200 sg:pub.10.1007/bf00337584 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030575298
201 https://doi.org/10.1007/bf00337584
202 rdf:type schema:CreativeWork
203 sg:pub.10.1007/bf01312224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024058813
204 https://doi.org/10.1007/bf01312224
205 rdf:type schema:CreativeWork
206 sg:pub.10.1007/bf01656599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039726392
207 https://doi.org/10.1007/bf01656599
208 rdf:type schema:CreativeWork
209 grid-institutes:grid.1957.a schema:alternateName Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany
210 Institute of Pathology, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany
211 schema:name Department of Surgery, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany
212 Institute of Pathology, Technical University Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany, Germany
213 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...