Oncologic outcome of colorectal cancer patients over age 80: a propensity score-matched analysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-08

AUTHORS

Bo Young Oh, Jung Wook Huh, Hee Cheol Kim, Yoon Ah Park, Yong Beom Cho, Seong Hyeon Yun, Woo Yong Lee, Ho-Kyung Chun

ABSTRACT

PURPOSE: It remains unclear whether old age is a poor prognostic factor in colorectal cancer (CRC). We compared oncologic outcomes in CRC patients according to age, using 80 as the dividing point. METHODS: CRC patients who underwent radical surgery from 2000 to 2011 were evaluated. We performed matched and adjusted analyses comparing oncologic outcomes between patients with ≥ 80 and < 80 years old. RESULTS: Among 9562 patients, 222 were elderly. The median age was 82.0 years in elderly patients and 59.0 years in young patients. Elderly patients received less neoadjuvant or adjuvant therapy compared to young patients (p < 0.001). After recurrence, significantly fewer elderly patients received additional treatments (p < 0.001). Before matching, disease-free survival (DFS) and cancer-specific survival (CSS) were significantly lower for elderly patients compared to those for young patients (p < 0.001 and p < 0.001, respectively). After matching, DFS and CCS were not significantly different between the two groups (p = 0.400 and p = 0.267, respectively). In a multivariate analysis for prognostic factors, old age was not an independent poor prognostic factor of DFS and CCS (p = 0.619 and p = 0.137, respectively). CONCLUSIONS: Elderly patients aged ≥ 80 years with CRC had similar oncologic outcome to young patients, and age was not an independent prognostic factor. More... »

PAGES

1011-1018

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00384-018-3028-4

DOI

http://dx.doi.org/10.1007/s00384-018-3028-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101671653

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29564541


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curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00384-018-3028-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00384-018-3028-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00384-018-3028-4'


 

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