Does pancreatico-biliary maljunction play a role in spontaneous perforation of the bile duct in children? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-11

AUTHORS

T. Hasegawa, Y. Udatsu, M. Kamiyama, T. Kimura, T. Sasaki, A. Okada, S. Mushiake

ABSTRACT

Spontaneous perforation of the bile duct (SPBD) is a rare disease in children. Pancreatico-biliary maljunction (PBM) has been postulated to contribute to its etiology. We have treated three children with SPBD over 30 years, two of whom had PBM. There was one boy and two girls aged 10 months to 2 years with symptoms of abdominal distension, vomiting, abdominal pain, jaundice, and acholic stools. The diagnosis of SPBD was made by paracentesis showing biliary ascites, and primary biliary and intra-abdominal drainage was performed in all cases. The site of perforation was at the connection of the common bile duct (CBD) with the cystic duct in all cases. In two cases reflux of contrast into the pancreatic duct was noted, the common channel was long (17 and 12 mm, respectively), and the bile amylase level in the CBD was abnormally high (50,000 and 67,000 IU/l, respectively). In the third patient there was no reflux of contrast into the pancreatic duct and the bile amylase and trypsin levels in the CBD and gallbladder were not measurable. Thus, SPBD in children may not be due solely to PBM, but may involve multiple mechanisms. More... »

PAGES

550-553

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s003830000433

DOI

http://dx.doi.org/10.1007/s003830000433

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013665402

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11149391


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