Weight gain velocity and adequate amount of nutrition for infants with congenital diaphragmatic hernia View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-11-28

AUTHORS

Keita Terui, Yuko Tazuke, Kouji Nagata, Miharu Ito, Hiroomi Okuyama, Masahiro Hayakawa, Tomoaki Taguchi, Yasunori Sato, Noriaki Usui

ABSTRACT

PurposeGrowth retardation is a severe morbidity in infants with congenital diaphragmatic hernia (CDH). This study aimed to determine when catch-up growth starts in infants with CDH and to determine the adequate amount of nutrition required during catch-up growth.MethodsThis was a multicenter retrospective cohort study involving neonates with isolated CDH (born 2006–2010; n = 98). Weight gain velocity (WGV) was calculated using body weight Z-scores. The minimum required weight gain was defined as WGV ≥ 0. Patients were dichotomized into severe and non-severe cases according to diaphragmatic defects.ResultsAverage monthly WGV changed from < 0 to ≥ 0 at 2 months of age. Total caloric intake at 2 months of age was lower when the WGV between 1 and 3 months was < 0 in both severe cases [122 (95% confidence interval (CI) 116–128) vs. 97 (95% CI 84–110) kcal/kg/day, p = 0.02] and non-severe cases [115 (95% CI 110–120) vs. 99 (95% CI 87–111) kcal/kg/day, p < 0.001)].ConclusionCatch-up growth started at approximately 2 months of age. During this period, total caloric intake of > 122 kcal/kg/day was needed to avoid decreases in the body weight Z-score in severe cases. More... »

PAGES

205-212

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00383-020-04785-y

DOI

http://dx.doi.org/10.1007/s00383-020-04785-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1132948646

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33247318


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