Choledochal malformations: global research, scientific advances and key controversies View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03

AUTHORS

Florian Friedmacher, Kathryn E. Ford, Mark Davenport

ABSTRACT

Choledochal malformations (CMs) represent a spectrum of relatively rare and complex congenital anomalies, characterized by abnormal dilatation of the biliary tract in the absence of any acute obstruction. Today, almost 20% of CMs can be detected in-utero using maternal ultrasonography. Formal scientometric analysis was used to identify where modern CM research is taking place and perhaps where our attention should be directed in the future. Thus, this article offers a comprehensive review of recent scientific advances relating to CMs including the current understanding of etiology and classification, whilst also discussing key controversies such as risk of malignant transformation and the role of newer modalities of surgical treatment. Although laparoscopic excision of CMs and biliary reconstruction is nowadays feasible and safe, care should be taken before dispensing with standard open techniques, which have minimal complication rates and proven long-term benefit. More... »

PAGES

273-282

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00383-018-4392-4

DOI

http://dx.doi.org/10.1007/s00383-018-4392-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1109759467

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30406431


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