Surgical treatment of childhood hepatoblastoma in the Netherlands (1990–2013) View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-01

AUTHORS

Linde A. D. Busweiler, Marc H. W. A. Wijnen, Jim C. H. Wilde, Egbert Sieders, Sheila E. J. Terwisscha van Scheltinga, L. W. Ernest van Heurn, Joseph Ziros, Roel Bakx, Hugo. A. Heij

ABSTRACT

BACKGROUND: Achievement of complete surgical resection plays a key role in the successful treatment of children with hepatoblastoma. The aim of this study is to assess the surgical outcomes after partial liver resections for hepatoblastoma, focusing on postoperative complications, resection margins, 30-day mortality, and long-term survival. METHOD: Chart reviews were carried out on all patients treated for hepatoblastoma in the Netherlands between 1990 and 2013. RESULTS: A total of 103 patients were included, of whom 94 underwent surgery. Partial hepatectomy was performed in 76 patients and 18 patients received a liver transplant as a primary procedure. In 42 of 73 (58 %) patients, one or more complications were reported. In 3 patients, information regarding complications was not available. Hemorrhage necessitating blood transfusion occurred in 33 (45 %) patients and 9 (12 %) patients developed biliary complications, of whom 8 needed one or more additional surgical interventions. Overall, 5-year disease-specific survival was 82, 92 % in the group of patients who underwent partial hepatectomy, and 77 % in the group of patients who underwent liver transplantation. CONCLUSIONS: Partial hepatectomy after chemotherapy in children with hepatoblastoma offers good chances of survival. This type of major surgery is associated with a high rate of surgical complications (58 %), which is not detrimental to survival. More... »

PAGES

23-31

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00383-016-3989-8

DOI

http://dx.doi.org/10.1007/s00383-016-3989-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053608117

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27730288


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00383-016-3989-8'


 

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319 https://www.grid.ac/institutes/grid.5650.6 schema:alternateName Academic Medical Center
320 schema:name Department of Pediatric Oncology, Emma Children’s Hospital-Academic Medical Center, Amsterdam, The Netherlands
321 rdf:type schema:Organization
 




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