Long-term survival of an infant with diffuse brainstem lesion diagnosed by prenatal MRI: a case report and review of the ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-06

AUTHORS

M. Suo-Palosaari, H. Rantala, S. Lehtinen, T. Kumpulainen, N. Salokorpi

ABSTRACT

BACKGROUND: We describe a unique case of expansive diffuse brainstem lesion diagnosed prenatally by magnetic resonance imaging (MRI) with long-term survival. Findings of fetal and postpartum MRI were highly consistent with the characteristics of diffuse brainstem glioma. METHODS: Diagnosis was based on the features of MRI, and histopathology was not confirmed by biopsy. Although the prognosis of diffuse brainstem tumor is usually poor, this child was asymptomatic at birth and the neurological condition is still normal at 4 years of age without any treatment. RESULTS: During routine imaging follow-up, diameters of the expansion have remained stable, while the size of the lesion compared to the posterior fossa size has diminished. In addition to brainstem tumor, a skin lesion of the back was observed and MRI of the thoracic spine showed a large asymptomatic extradural cystic lesion suggesting an arachnoid cyst. The pontine tumor of this infant, in agreement with a few previously reported cases, suggests a subgroup of beneficial outcome of expansive diffuse brainstem lesions, particularly in the neonatal period. DISCUSSION: In this article, we discuss the prognosis and characteristics of pediatric brainstem tumors and differential diagnosis of neonatal brainstem lesions. More... »

PAGES

1163-1168

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00381-016-3045-y

    DOI

    http://dx.doi.org/10.1007/s00381-016-3045-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1025839342

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26906478


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