Ontology type: schema:ScholarlyArticle
2014-05-17
AUTHORSL. Guilbaud, C. Garabedian, F. Di Rocco, C. Fallet-Bianco, S. Friszer, M. Zerah, J. M. Jouannic
ABSTRACTPurposeThe prevention of Chiari type II malformation (CM) is commonly used as a primary outcome for the evaluation of techniques of fetal myelomeningocele (MMC) surgery in the fetal lamb. The aim of our study was to investigate the frequency of the associated CM in the MMC fetal sheep model and to investigate the contribution of prenatal ultrasound evaluation of CM at the time of prenatal repair.MethodsA MMC-like lesion was surgically created at 75 days of gestation in 21 fetuses performing a L1–L5 laminectomy followed by an excision of the exposed dura and a midline myelotomy. At a 90-day gestation, among the 19 alived fetuses, a conventional repair of the MMC-like lesion was performed in seven, four of whom underwent cerebral ultrasound (US) examination before the repair. Twelve fetuses remained untreated (control group). All fetuses underwent post-mortem examination (PM) at 138 days.ResultsAt a 90-day gestation, CM was demonstrated by US examination in all four evaluated fetuses. At birth, CM was found in 3/6 control whether CM was absent in all alived fetuses in the prenatal repair group (n = 4).ConclusionsCreation of a MMC-like lesion with an additional myelotomy does not always lead to hindbrain herniation. Our study suggests that CM should be assessed by ultrasound examination at the time of the prenatal repair to demonstrate the effectiveness of new techniques for the prenatal repair of MMC. More... »
PAGES1425-1429
http://scigraph.springernature.com/pub.10.1007/s00381-014-2426-3
DOIhttp://dx.doi.org/10.1007/s00381-014-2426-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1029999153
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/24839036
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Paediatrics and Reproductive Medicine",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Arnold-Chiari Malformation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Disease Models, Animal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Embryo, Mammalian",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Fetus",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gestational Age",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Laminectomy",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Meningomyelocele",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Models, Anatomic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Sheep",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Ultrasonography",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France",
"id": "http://www.grid.ac/institutes/grid.413776.0",
"name": [
"Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France"
],
"type": "Organization"
},
"familyName": "Guilbaud",
"givenName": "L.",
"id": "sg:person.01103161576.22",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103161576.22"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France",
"id": "http://www.grid.ac/institutes/grid.413776.0",
"name": [
"Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France"
],
"type": "Organization"
},
"familyName": "Garabedian",
"givenName": "C.",
"id": "sg:person.01230274102.45",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230274102.45"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Service de Neurochirurgie P\u00e9diatrique, H\u00f4pital Necker Enfants Malades, APHP, Paris 5, 149 Rue de S\u00e8vres, 75015, Paris, France",
"id": "http://www.grid.ac/institutes/grid.412134.1",
"name": [
"Service de Neurochirurgie P\u00e9diatrique, H\u00f4pital Necker Enfants Malades, APHP, Paris 5, 149 Rue de S\u00e8vres, 75015, Paris, France"
],
"type": "Organization"
},
"familyName": "Di Rocco",
"givenName": "F.",
"id": "sg:person.01277017227.22",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277017227.22"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Laboratoire de Neuropathologie, H\u00f4pital Sainte Justine, 3175 Chemin de la C\u00f4te-Sainte-Catherine, QC H3T 1C5, Montr\u00e9al, QC, Canada",
"id": "http://www.grid.ac/institutes/grid.411418.9",
"name": [
"Laboratoire de Neuropathologie, H\u00f4pital Sainte Justine, 3175 Chemin de la C\u00f4te-Sainte-Catherine, QC H3T 1C5, Montr\u00e9al, QC, Canada"
],
"type": "Organization"
},
"familyName": "Fallet-Bianco",
"givenName": "C.",
"id": "sg:person.01271775461.29",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271775461.29"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France",
"id": "http://www.grid.ac/institutes/grid.413776.0",
"name": [
"Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France"
],
"type": "Organization"
},
"familyName": "Friszer",
"givenName": "S.",
"id": "sg:person.01000262551.54",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000262551.54"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Service de Neurochirurgie P\u00e9diatrique, H\u00f4pital Necker Enfants Malades, APHP, Paris 5, 149 Rue de S\u00e8vres, 75015, Paris, France",
"id": "http://www.grid.ac/institutes/grid.412134.1",
"name": [
"Service de Neurochirurgie P\u00e9diatrique, H\u00f4pital Necker Enfants Malades, APHP, Paris 5, 149 Rue de S\u00e8vres, 75015, Paris, France"
],
"type": "Organization"
},
"familyName": "Zerah",
"givenName": "M.",
"id": "sg:person.01367530351.64",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367530351.64"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France",
"id": "http://www.grid.ac/institutes/grid.413776.0",
"name": [
"Unit\u00e9 de M\u00e9decine F\u0153tale et d\u2019Echographie, P\u00f4le de P\u00e9rinatalit\u00e9, H\u00f4pital Armand Trousseau, APHP, Paris 6, 26 Avenue A. Netter, 75012, Paris, France"
],
"type": "Organization"
},
"familyName": "Jouannic",
"givenName": "J. M.",
"id": "sg:person.01324052660.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324052660.08"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s00383-008-2276-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038117453",
"https://doi.org/10.1007/s00383-008-2276-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00464-013-2984-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023209240",
"https://doi.org/10.1007/s00464-013-2984-6"
],
"type": "CreativeWork"
}
],
"datePublished": "2014-05-17",
"datePublishedReg": "2014-05-17",
"description": "PurposeThe prevention of Chiari type II malformation (CM) is commonly used as a primary outcome for the evaluation of techniques of fetal myelomeningocele (MMC) surgery in the fetal lamb. The aim of our study was to investigate the frequency of the associated CM in the MMC fetal sheep model and to investigate the contribution of prenatal ultrasound evaluation of CM at the time of prenatal repair.MethodsA MMC-like lesion was surgically created at 75\u00a0days of gestation in 21 fetuses performing a L1\u2013L5 laminectomy followed by an excision of the exposed dura and a midline myelotomy. At a 90-day gestation, among the 19 alived fetuses, a conventional repair of the MMC-like lesion was performed in seven, four of whom underwent cerebral ultrasound (US) examination before the repair. Twelve fetuses remained untreated (control group). All fetuses underwent post-mortem examination (PM) at 138\u00a0days.ResultsAt a 90-day gestation, CM was demonstrated by US examination in all four evaluated fetuses. At birth, CM was found in 3/6 control whether CM was absent in all alived fetuses in the prenatal repair group (n\u2009=\u20094).ConclusionsCreation of a MMC-like lesion with an additional myelotomy does not always lead to hindbrain herniation. Our study suggests that CM should be assessed by ultrasound examination at the time of the prenatal repair to demonstrate the effectiveness of new techniques for the prenatal repair of MMC.",
"genre": "article",
"id": "sg:pub.10.1007/s00381-014-2426-3",
"inLanguage": "en",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1095355",
"issn": [
"0256-7040",
"1433-0350"
],
"name": "Child's Nervous System",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "8",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "30"
}
],
"keywords": [
"Chiari type II malformation",
"post-mortem examination",
"prenatal repair",
"ultrasound examination",
"fetal myelomeningocele surgery",
"cerebral ultrasound examination",
"prenatal repair group",
"prenatal ultrasound evaluation",
"type II malformation",
"days of gestation",
"fetal sheep model",
"midline myelotomy",
"primary outcome",
"ultrasound evaluation",
"myelomeningocele surgery",
"fetal lambs",
"US examination",
"fetal sheep",
"repair group",
"hindbrain herniation",
"conventional repair",
"fetuses",
"sheep model",
"gestation",
"lesions",
"myelotomy",
"repair",
"examination",
"days",
"laminectomy",
"herniation",
"surgery",
"myelomeningocele",
"ConclusionsCreation",
"ResultsAt",
"excision",
"malformations",
"dura",
"prevention",
"evaluation of techniques",
"birth",
"outcomes",
"evaluation",
"study",
"lambs",
"group",
"aim",
"sheep",
"control",
"new technique",
"time",
"MMC",
"frequency",
"effectiveness",
"technique",
"model",
"contribution",
"limit"
],
"name": "Limits of the surgically induced model of myelomeningocele in the fetal sheep",
"pagination": "1425-1429",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1029999153"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00381-014-2426-3"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"24839036"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00381-014-2426-3",
"https://app.dimensions.ai/details/publication/pub.1029999153"
],
"sdDataset": "articles",
"sdDatePublished": "2022-06-01T22:13",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220601/entities/gbq_results/article/article_630.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s00381-014-2426-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00381-014-2426-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00381-014-2426-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00381-014-2426-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00381-014-2426-3'
This table displays all metadata directly associated to this object as RDF triples.
220 TRIPLES
22 PREDICATES
97 URIs
87 LITERALS
18 BLANK NODES