Ontology type: schema:ScholarlyArticle
2005-01-19
AUTHORSN. Horinaka, Y. Ito, M. Miyajima, M. Hishii, K. Suzuki, M. Saito, H. Arai
ABSTRACTIntroductionPeripheral primitive neuroectodermal tumor (PNET) occurring as an extra-axial lesion within the intracranial space and extending to the subarachnoid space is extremely rare.Case report An 18-month-old girl presented with an intracranial peripheral PNET manifesting as abducens nerve palsy. Magnetic resonance imaging on admission revealed a lesion affecting the trigeminal and abducens nerves. The tumor was partially removed via the subtemporal approach. Histological examination showed a high-grade, undifferentiated neoplasm of small cell type with positive immunostaining for MIC2. The histological diagnosis was peripheral PNET.Outcome Craniospinal radiotherapy reduced the tumor size, but adjuvant chemotherapy designed for Ewing’s sarcomas and PNETs was not effective. She died 1 month after the last chemotherapy, despite whole craniospinal irradiation (total dose 53.2 Gy) and chemotherapy. More... »
PAGES327-330
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DOIhttp://dx.doi.org/10.1007/s00381-004-1053-9
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/15657787
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