Ontology type: schema:ScholarlyArticle
2021-11-22
AUTHORSRyota Noike, Hideo Amano, Shinya Suzuki, Hiroto Kano, Yuji Oikawa, Junji Yajima, Shojiro Hirano, Yoshimasa Kojima, Yosuke Oka, Hiroto Aikawa, Shingo Matsumoto, Takayuki Yabe, Ryo Okubo, Rine Nakanishi, Takuto Arita, Naoharu Yagi, Mikio Kishi, Hiroaki Semba, Shunsuke Matsuno, Yuko Kato, Takayuki Otsuka, Tokuhisa Uejima, Minoru Matsuhama, Mitsuru Iida, Takeshi Yamashita, Takanori Ikeda
ABSTRACTGlasgow prognostic score (GPS) has been used to evaluate inflammatory response and nutritional status. This study aimed to investigate the impact of nutritional status on cardiac prognosis by using GPS in patients after undergoing percutaneous coronary intervention (PCI). We included 862 patients who underwent PCI for stable angina pectoris between 2015 and 2018. We used the original cutoff values, which were an albumin (Alb) level of 3.5 g/dl and a C-reactive protein (CRP) level of 0.3 mg/dl. We categorized them into the three groups: originally defined GPS (od-GPS) 0 (high Alb and low CRP), 1 (low Alb or high CRP), and 2 (low Alb and high CRP). Major adverse clinical events (MACEs) included all-cause death, nonfatal myocardial infarction, revascularization, and hospitalization for heart failure. The median follow-up period was 398.5 days. During the follow-up, MACEs occurred in 136 patients. Od-GPS 2 had higher prevalence rates in terms of chronic kidney disease (CKD; 31.7% [229/722] vs. 44.9% [53/118] vs. 63.6% [14/22], p < 0.001), hemodialysis (6.4% [46/722] vs. 14.4% [17/118] vs. 31.8% [7/22], p < 0.001), and heart failure cases (HF; 9.1% [66/722] vs. 14.4% [17/118] vs. 27.3% [6/22], p = 0.007), with higher creatinine (1.17 ± 1.37 mg/dl vs. 1.89 ± 2.60 mg/dl vs. 3.49 ± 4.01 mg/dl, p < 0.001) and brain natriuretic peptide levels (104.1 ± 304.6 pg/ml vs. 242.4 ± 565.9 pg/ml vs. 668.1 ± 872.2 pg/ml, p < 0.001) and lower low-density lipoprotein cholesterol (101.5 ± 32.9 mg/dl vs. 98.2 ± 28.8 mg/dl vs. 77.1 ± 24.3 mg/dl, p = 0.002) than od-GPS 0 and 1.Od-GPS 2 (HR 2.42; 95% CI 1.16–5.02; p = 0.018), od-GPS 1 (HR 2.09; 95% CI 1.40–3.13; p < 0.001), diabetes (HR 1.41; 95% CI 1.00–1.99; p = 0.048), CKD (HR 2.10; 95% CI 1.49–2.96; p < 0.001), and HF (HR 1.64; 95% CI 1.05–2.56; p = 0.029) were independent predictors of MACEs. A scoring system using CRP and Alb levels with a milder definition than GPS suitably predicted the risk of MACEs in the patients who underwent PCI. More... »
PAGES1-8
http://scigraph.springernature.com/pub.10.1007/s00380-021-01986-w
DOIhttp://dx.doi.org/10.1007/s00380-021-01986-w
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/34807279
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"description": "Glasgow prognostic score (GPS) has been used to evaluate inflammatory response and nutritional status. This study aimed to investigate the impact of nutritional status on cardiac prognosis by using GPS in patients after undergoing percutaneous coronary intervention (PCI). We included 862 patients who underwent PCI for stable angina pectoris between 2015 and 2018. We used the original cutoff values, which were an albumin (Alb) level of 3.5\u00a0g/dl and a C-reactive protein (CRP) level of 0.3\u00a0mg/dl. We categorized them into the three groups: originally defined GPS (od-GPS) 0 (high Alb and low CRP), 1 (low Alb or high CRP), and 2 (low Alb and high CRP). Major adverse clinical events (MACEs) included all-cause death, nonfatal myocardial infarction, revascularization, and hospitalization for heart failure. The median follow-up period was 398.5\u00a0days. During the follow-up, MACEs occurred in 136 patients. Od-GPS 2 had higher prevalence rates in terms of chronic kidney disease (CKD; 31.7% [229/722] vs. 44.9% [53/118] vs. 63.6% [14/22], p\u2009<\u20090.001), hemodialysis (6.4% [46/722] vs. 14.4% [17/118] vs. 31.8% [7/22], p\u2009<\u20090.001), and heart failure cases (HF; 9.1% [66/722] vs. 14.4% [17/118] vs. 27.3% [6/22], p\u2009=\u20090.007), with higher creatinine (1.17\u2009\u00b1\u20091.37\u00a0mg/dl vs. 1.89\u2009\u00b1\u20092.60\u00a0mg/dl vs. 3.49\u2009\u00b1\u20094.01\u00a0mg/dl, p\u2009<\u20090.001) and brain natriuretic peptide levels (104.1\u2009\u00b1\u2009304.6\u00a0pg/ml vs. 242.4\u2009\u00b1\u2009565.9\u00a0pg/ml vs. 668.1\u2009\u00b1\u2009872.2\u00a0pg/ml, p\u2009<\u20090.001) and lower low-density lipoprotein cholesterol (101.5\u2009\u00b1\u200932.9\u00a0mg/dl vs. 98.2\u2009\u00b1\u200928.8\u00a0mg/dl vs. 77.1\u2009\u00b1\u200924.3\u00a0mg/dl, p\u2009=\u20090.002) than od-GPS 0 and 1.Od-GPS 2 (HR 2.42; 95% CI 1.16\u20135.02; p\u2009=\u20090.018), od-GPS 1 (HR 2.09; 95% CI 1.40\u20133.13; p\u2009<\u20090.001), diabetes (HR 1.41; 95% CI 1.00\u20131.99; p\u2009=\u20090.048), CKD (HR 2.10; 95% CI 1.49\u20132.96; p\u2009<\u20090.001), and HF (HR 1.64; 95% CI 1.05\u20132.56; p\u2009=\u20090.029) were independent predictors of MACEs. A scoring system using CRP and Alb levels with a milder definition than GPS suitably predicted the risk of MACEs in the patients who underwent PCI.",
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]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01986-w'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01986-w'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01986-w'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01986-w'
This table displays all metadata directly associated to this object as RDF triples.
333 TRIPLES
22 PREDICATES
108 URIs
94 LITERALS
5 BLANK NODES