Catheter ablation of ganglionated plexi in patients with adenosine triphosphate-induced atrial fibrillation after pulmonary vein isolation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-11-06

AUTHORS

Taku Nishida, Akihiro Takitsume, Junichi Sugiura, Ayaka Keshi, Koshiro Kanaoka, Kaeko Hirai, Hiroki Yano, Yukihiro Hashimoto, Tomoya Ueda, Hitoshi Nakagawa, Kenji Onoue, Tsunenari Soeda, Makoto Watanabe, Rika Kawakami, Yoshihiko Saito

ABSTRACT

Intravenous ATP may induce atrial fibrillation (AF). ATP shares similar receptor–effector coupling systems with acetylcholine. However, the association between an ATP injection and the hyperactivity of the intrinsic cardiac autonomic nervous system, known as ganglionated plexi (GPs), is not well understood. We describe a series of patients with non-pulmonary vein (PV) trigger sites provoked by an ATP injection, and assess the feasibility of a ganglionated plexus (GP) ablation. We retrospectively analyzed 547 patients (69% male; mean age 67.4 ± 10.4 years; 38.5% non-paroxysmal AF) who underwent a total of 604 ablation procedures. Intravenous ATP was administered with an isoproterenol infusion during sinus rhythm after a pulmonary vein isolation in 21.3%, Box isolation in 78.6%, and SVC isolation in 52.0% of the procedures, respectively. We reviewed the incidence, the distribution of the foci, and the ablation outcomes in patients with ATP-induced AF. A total of seven patients (1.3%) had ATP-induced AF. Foci were identified in the coronary sinus (CS) in six patients, right atrial posterior wall (RAPW) adjacent to the interatrial groove in two, mitral annulus in two, ligament of Marshall in one, right septum below the foramen ovale in one and left atrial posterior wall in one, respectively. Among these trigger foci, we confirmed the vagal response by high-frequency stimulation in the CS and RAPW in six and two patients, respectively. After a median RF time of 2.9 min (range 2.5–11.3) targeting these foci, in five of six patients who received a repeat ATP injection, the AF became non-inducible. ATP-provoked trigger foci were distributed among certain sites that overlapped with the distribution of the GPs. The GP ablation was effective for this rare, but challenging situation. More... »

PAGES

854-866

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-021-01979-9

DOI

http://dx.doi.org/10.1007/s00380-021-01979-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1142416367

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34741632


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenosine Triphosphate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Atrial Fibrillation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Catheter Ablation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pulmonary Veins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishida", 
        "givenName": "Taku", 
        "id": "sg:person.0627605642.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627605642.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiology, Nara Prefecture General Medical Center, Kashihara, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Cardiology, Nara Prefecture General Medical Center, Kashihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takitsume", 
        "givenName": "Akihiro", 
        "id": "sg:person.01245111427.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245111427.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sugiura", 
        "givenName": "Junichi", 
        "id": "sg:person.013626103316.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013626103316.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Keshi", 
        "givenName": "Ayaka", 
        "id": "sg:person.016065413100.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016065413100.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kanaoka", 
        "givenName": "Koshiro", 
        "id": "sg:person.012753322153.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012753322153.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiology, Nara Prefecture Seiwa Medical Center, Kashihara, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Cardiology, Nara Prefecture Seiwa Medical Center, Kashihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirai", 
        "givenName": "Kaeko", 
        "id": "sg:person.013050736357.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013050736357.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yano", 
        "givenName": "Hiroki", 
        "id": "sg:person.011246247537.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011246247537.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hashimoto", 
        "givenName": "Yukihiro", 
        "id": "sg:person.07672737335.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07672737335.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ueda", 
        "givenName": "Tomoya", 
        "id": "sg:person.01015603231.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015603231.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakagawa", 
        "givenName": "Hitoshi", 
        "id": "sg:person.0645247710.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645247710.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Onoue", 
        "givenName": "Kenji", 
        "id": "sg:person.01176456440.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176456440.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Soeda", 
        "givenName": "Tsunenari", 
        "id": "sg:person.0746001440.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746001440.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Watanabe", 
        "givenName": "Makoto", 
        "id": "sg:person.010526245644.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010526245644.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kawakami", 
        "givenName": "Rika", 
        "id": "sg:person.01025461325.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025461325.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410814.8", 
          "name": [
            "Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saito", 
        "givenName": "Yoshihiko", 
        "id": "sg:person.015126315422.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015126315422.61"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00380-019-01431-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1115023609", 
          "https://doi.org/10.1007/s00380-019-01431-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10840-013-9862-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030643241", 
          "https://doi.org/10.1007/s10840-013-9862-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00380-021-01820-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1136236670", 
          "https://doi.org/10.1007/s00380-021-01820-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10840-008-9252-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041070636", 
          "https://doi.org/10.1007/s10840-008-9252-z"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2021-11-06", 
    "datePublishedReg": "2021-11-06", 
    "description": "Intravenous ATP may induce atrial fibrillation (AF). ATP shares similar receptor\u2013effector coupling systems with acetylcholine. However, the association between an ATP injection and the hyperactivity of the intrinsic cardiac autonomic nervous system, known as ganglionated plexi (GPs), is not well understood. We describe a series of patients with non-pulmonary vein (PV) trigger sites provoked by an ATP injection, and assess the feasibility of a ganglionated plexus (GP) ablation. We retrospectively analyzed 547 patients (69% male; mean age 67.4\u2009\u00b1\u200910.4\u00a0years; 38.5% non-paroxysmal AF) who underwent a total of 604 ablation procedures. Intravenous ATP was administered with an isoproterenol infusion during sinus rhythm after a pulmonary vein isolation in 21.3%, Box isolation in 78.6%, and SVC isolation in 52.0% of the procedures, respectively. We reviewed the incidence, the distribution of the foci, and the ablation outcomes in patients with ATP-induced AF. A total of seven patients (1.3%) had ATP-induced AF. Foci were identified in the coronary sinus (CS) in six patients, right atrial posterior wall (RAPW) adjacent to the interatrial groove in two, mitral annulus in two, ligament of Marshall in one, right septum below the foramen ovale in one and left atrial posterior wall in one, respectively. Among these trigger foci, we confirmed the vagal response by high-frequency stimulation in the CS and RAPW in six and two patients, respectively. After a median RF time of 2.9\u00a0min (range 2.5\u201311.3) targeting these foci, in five of six patients who received a repeat ATP injection, the AF became non-inducible. ATP-provoked trigger foci were distributed among certain sites that overlapped with the distribution of the GPs. The GP ablation was effective for this rare, but challenging situation.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00380-021-01979-9", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1095887", 
        "issn": [
          "0910-8327", 
          "1615-2573"
        ], 
        "name": "Heart and Vessels", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "37"
      }
    ], 
    "keywords": [
      "right atrial posterior wall", 
      "pulmonary vein isolation", 
      "atrial fibrillation", 
      "atrial posterior wall", 
      "coronary sinus", 
      "ATP injection", 
      "intravenous ATP", 
      "vein isolation", 
      "posterior wall", 
      "intrinsic cardiac autonomic nervous system", 
      "cardiac autonomic nervous system", 
      "ligament of Marshall", 
      "series of patients", 
      "autonomic nervous system", 
      "high-frequency stimulation", 
      "SVC isolation", 
      "GP ablation", 
      "plexus ablation", 
      "catheter ablation", 
      "isoproterenol infusion", 
      "sinus rhythm", 
      "vagal response", 
      "ablation outcomes", 
      "mitral annulus", 
      "interatrial groove", 
      "ablation procedures", 
      "patients", 
      "nervous system", 
      "box isolation", 
      "RF time", 
      "trigger sites", 
      "right septum", 
      "fibrillation", 
      "plexi", 
      "injection", 
      "ablation", 
      "total", 
      "ATP", 
      "acetylcholine", 
      "sinus", 
      "infusion", 
      "hyperactivity", 
      "foramen", 
      "incidence", 
      "challenging situations", 
      "ligament", 
      "septum", 
      "stimulation", 
      "outcomes", 
      "association", 
      "rhythm", 
      "GPs", 
      "procedure", 
      "isolation", 
      "min", 
      "response", 
      "focus", 
      "wall", 
      "sites", 
      "certain sites", 
      "annulus", 
      "feasibility", 
      "time", 
      "series", 
      "system", 
      "distribution", 
      "situation", 
      "groove", 
      "Marshall", 
      "coupling system"
    ], 
    "name": "Catheter ablation of ganglionated plexi in patients with adenosine triphosphate-induced atrial fibrillation after pulmonary vein isolation", 
    "pagination": "854-866", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1142416367"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00380-021-01979-9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "34741632"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00380-021-01979-9", 
      "https://app.dimensions.ai/details/publication/pub.1142416367"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T10:28", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_880.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00380-021-01979-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01979-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01979-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01979-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00380-021-01979-9'


 

This table displays all metadata directly associated to this object as RDF triples.

295 TRIPLES      22 PREDICATES      111 URIs      99 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00380-021-01979-9 schema:about N2a4afd2a65d64aac9b54c6f4d82c7ee5
2 N35955bfa6ab94242af696b27f554b78e
3 N39652fc49640408bbf7c4b78f76514aa
4 N4195a5359186473f965b3cda18a4e358
5 N6299e9feb7934a7dbba86d7032b3c943
6 N6b4b710790e04183bbd94c2c691822f3
7 N723987805be446f8a4fcb69748a8a84f
8 N8eeeb38e54d443b8b2bb40009fa4d90c
9 Naaa36506b6e74b71b8abf39590447c75
10 Nbf534c2d466c4b2c8cacb501c59d2880
11 Ne8b05f6084c44e8fa9d21c2c8fbe92c1
12 anzsrc-for:11
13 anzsrc-for:1102
14 schema:author N6ab23fd8f7ae4b6f8c9d91d91cfdd2bd
15 schema:citation sg:pub.10.1007/s00380-019-01431-z
16 sg:pub.10.1007/s00380-021-01820-3
17 sg:pub.10.1007/s10840-008-9252-z
18 sg:pub.10.1007/s10840-013-9862-y
19 schema:datePublished 2021-11-06
20 schema:datePublishedReg 2021-11-06
21 schema:description Intravenous ATP may induce atrial fibrillation (AF). ATP shares similar receptor–effector coupling systems with acetylcholine. However, the association between an ATP injection and the hyperactivity of the intrinsic cardiac autonomic nervous system, known as ganglionated plexi (GPs), is not well understood. We describe a series of patients with non-pulmonary vein (PV) trigger sites provoked by an ATP injection, and assess the feasibility of a ganglionated plexus (GP) ablation. We retrospectively analyzed 547 patients (69% male; mean age 67.4 ± 10.4 years; 38.5% non-paroxysmal AF) who underwent a total of 604 ablation procedures. Intravenous ATP was administered with an isoproterenol infusion during sinus rhythm after a pulmonary vein isolation in 21.3%, Box isolation in 78.6%, and SVC isolation in 52.0% of the procedures, respectively. We reviewed the incidence, the distribution of the foci, and the ablation outcomes in patients with ATP-induced AF. A total of seven patients (1.3%) had ATP-induced AF. Foci were identified in the coronary sinus (CS) in six patients, right atrial posterior wall (RAPW) adjacent to the interatrial groove in two, mitral annulus in two, ligament of Marshall in one, right septum below the foramen ovale in one and left atrial posterior wall in one, respectively. Among these trigger foci, we confirmed the vagal response by high-frequency stimulation in the CS and RAPW in six and two patients, respectively. After a median RF time of 2.9 min (range 2.5–11.3) targeting these foci, in five of six patients who received a repeat ATP injection, the AF became non-inducible. ATP-provoked trigger foci were distributed among certain sites that overlapped with the distribution of the GPs. The GP ablation was effective for this rare, but challenging situation.
22 schema:genre article
23 schema:inLanguage en
24 schema:isAccessibleForFree true
25 schema:isPartOf N509b88e539834b388b445d9853ffc378
26 Na0fb5549aa1a45d09a540227c88a7c8e
27 sg:journal.1095887
28 schema:keywords ATP
29 ATP injection
30 GP ablation
31 GPs
32 Marshall
33 RF time
34 SVC isolation
35 ablation
36 ablation outcomes
37 ablation procedures
38 acetylcholine
39 annulus
40 association
41 atrial fibrillation
42 atrial posterior wall
43 autonomic nervous system
44 box isolation
45 cardiac autonomic nervous system
46 catheter ablation
47 certain sites
48 challenging situations
49 coronary sinus
50 coupling system
51 distribution
52 feasibility
53 fibrillation
54 focus
55 foramen
56 groove
57 high-frequency stimulation
58 hyperactivity
59 incidence
60 infusion
61 injection
62 interatrial groove
63 intravenous ATP
64 intrinsic cardiac autonomic nervous system
65 isolation
66 isoproterenol infusion
67 ligament
68 ligament of Marshall
69 min
70 mitral annulus
71 nervous system
72 outcomes
73 patients
74 plexi
75 plexus ablation
76 posterior wall
77 procedure
78 pulmonary vein isolation
79 response
80 rhythm
81 right atrial posterior wall
82 right septum
83 septum
84 series
85 series of patients
86 sinus
87 sinus rhythm
88 sites
89 situation
90 stimulation
91 system
92 time
93 total
94 trigger sites
95 vagal response
96 vein isolation
97 wall
98 schema:name Catheter ablation of ganglionated plexi in patients with adenosine triphosphate-induced atrial fibrillation after pulmonary vein isolation
99 schema:pagination 854-866
100 schema:productId N39f7274da5164255afaa8cf2690ca1f3
101 Na6a7cdbf990a473d866ce44287ee1568
102 Na8e9087419bd4497bf8db8ecf73e6570
103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1142416367
104 https://doi.org/10.1007/s00380-021-01979-9
105 schema:sdDatePublished 2022-05-10T10:28
106 schema:sdLicense https://scigraph.springernature.com/explorer/license/
107 schema:sdPublisher N0bc19a6e52ec47849496534403895d23
108 schema:url https://doi.org/10.1007/s00380-021-01979-9
109 sgo:license sg:explorer/license/
110 sgo:sdDataset articles
111 rdf:type schema:ScholarlyArticle
112 N08dabf620fca438cb017f61866a5e175 rdf:first sg:person.01025461325.73
113 rdf:rest Nc4b2d8e95cb949dd90766b772e6214c4
114 N0bc19a6e52ec47849496534403895d23 schema:name Springer Nature - SN SciGraph project
115 rdf:type schema:Organization
116 N1d856d8602274ac596e4a5d9918f5102 rdf:first sg:person.013626103316.95
117 rdf:rest N934fdb1c8e814a3081871a293b5f0ef7
118 N23348f2a9afd4599814365e2bfa584ff rdf:first sg:person.07672737335.45
119 rdf:rest N359ca5234d68446e8bc29056c81eb2c5
120 N2a4afd2a65d64aac9b54c6f4d82c7ee5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Atrial Fibrillation
122 rdf:type schema:DefinedTerm
123 N35955bfa6ab94242af696b27f554b78e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Retrospective Studies
125 rdf:type schema:DefinedTerm
126 N359ca5234d68446e8bc29056c81eb2c5 rdf:first sg:person.01015603231.79
127 rdf:rest N492fa39a3f4a48da8c705ec59cd194fa
128 N37cc64ddb20b405c9564793c19112fd4 rdf:first sg:person.010526245644.50
129 rdf:rest N08dabf620fca438cb017f61866a5e175
130 N39652fc49640408bbf7c4b78f76514aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Male
132 rdf:type schema:DefinedTerm
133 N39f7274da5164255afaa8cf2690ca1f3 schema:name doi
134 schema:value 10.1007/s00380-021-01979-9
135 rdf:type schema:PropertyValue
136 N4195a5359186473f965b3cda18a4e358 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Catheter Ablation
138 rdf:type schema:DefinedTerm
139 N4469ee46e45b44d28ca070996391c9a6 rdf:first sg:person.011246247537.35
140 rdf:rest N23348f2a9afd4599814365e2bfa584ff
141 N492fa39a3f4a48da8c705ec59cd194fa rdf:first sg:person.0645247710.78
142 rdf:rest N888b75b79cfe4461b5f3986a9e38862a
143 N509b88e539834b388b445d9853ffc378 schema:volumeNumber 37
144 rdf:type schema:PublicationVolume
145 N53b8f3abf7e8487baddae63803f95807 rdf:first sg:person.013050736357.32
146 rdf:rest N4469ee46e45b44d28ca070996391c9a6
147 N6299e9feb7934a7dbba86d7032b3c943 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Middle Aged
149 rdf:type schema:DefinedTerm
150 N66e160dcbe144283b9fbc3527e34e8c4 rdf:first sg:person.0746001440.76
151 rdf:rest N37cc64ddb20b405c9564793c19112fd4
152 N6ab23fd8f7ae4b6f8c9d91d91cfdd2bd rdf:first sg:person.0627605642.08
153 rdf:rest Ndedef570fdea46daa38904e3315b3ee7
154 N6b4b710790e04183bbd94c2c691822f3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Adenosine Triphosphate
156 rdf:type schema:DefinedTerm
157 N723987805be446f8a4fcb69748a8a84f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Treatment Outcome
159 rdf:type schema:DefinedTerm
160 N888b75b79cfe4461b5f3986a9e38862a rdf:first sg:person.01176456440.98
161 rdf:rest N66e160dcbe144283b9fbc3527e34e8c4
162 N8eeeb38e54d443b8b2bb40009fa4d90c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Pulmonary Veins
164 rdf:type schema:DefinedTerm
165 N934fdb1c8e814a3081871a293b5f0ef7 rdf:first sg:person.016065413100.98
166 rdf:rest Nbd1769baf7884be5bb763f1da5bfbd6d
167 Na0fb5549aa1a45d09a540227c88a7c8e schema:issueNumber 5
168 rdf:type schema:PublicationIssue
169 Na6a7cdbf990a473d866ce44287ee1568 schema:name pubmed_id
170 schema:value 34741632
171 rdf:type schema:PropertyValue
172 Na8e9087419bd4497bf8db8ecf73e6570 schema:name dimensions_id
173 schema:value pub.1142416367
174 rdf:type schema:PropertyValue
175 Naaa36506b6e74b71b8abf39590447c75 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Aged
177 rdf:type schema:DefinedTerm
178 Nbd1769baf7884be5bb763f1da5bfbd6d rdf:first sg:person.012753322153.25
179 rdf:rest N53b8f3abf7e8487baddae63803f95807
180 Nbf534c2d466c4b2c8cacb501c59d2880 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Humans
182 rdf:type schema:DefinedTerm
183 Nc4b2d8e95cb949dd90766b772e6214c4 rdf:first sg:person.015126315422.61
184 rdf:rest rdf:nil
185 Ndedef570fdea46daa38904e3315b3ee7 rdf:first sg:person.01245111427.53
186 rdf:rest N1d856d8602274ac596e4a5d9918f5102
187 Ne8b05f6084c44e8fa9d21c2c8fbe92c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Female
189 rdf:type schema:DefinedTerm
190 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
191 schema:name Medical and Health Sciences
192 rdf:type schema:DefinedTerm
193 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
194 schema:name Cardiorespiratory Medicine and Haematology
195 rdf:type schema:DefinedTerm
196 sg:journal.1095887 schema:issn 0910-8327
197 1615-2573
198 schema:name Heart and Vessels
199 schema:publisher Springer Nature
200 rdf:type schema:Periodical
201 sg:person.01015603231.79 schema:affiliation grid-institutes:grid.410814.8
202 schema:familyName Ueda
203 schema:givenName Tomoya
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015603231.79
205 rdf:type schema:Person
206 sg:person.01025461325.73 schema:affiliation grid-institutes:grid.410814.8
207 schema:familyName Kawakami
208 schema:givenName Rika
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025461325.73
210 rdf:type schema:Person
211 sg:person.010526245644.50 schema:affiliation grid-institutes:grid.410814.8
212 schema:familyName Watanabe
213 schema:givenName Makoto
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010526245644.50
215 rdf:type schema:Person
216 sg:person.011246247537.35 schema:affiliation grid-institutes:grid.410814.8
217 schema:familyName Yano
218 schema:givenName Hiroki
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011246247537.35
220 rdf:type schema:Person
221 sg:person.01176456440.98 schema:affiliation grid-institutes:grid.410814.8
222 schema:familyName Onoue
223 schema:givenName Kenji
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176456440.98
225 rdf:type schema:Person
226 sg:person.01245111427.53 schema:affiliation grid-institutes:None
227 schema:familyName Takitsume
228 schema:givenName Akihiro
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245111427.53
230 rdf:type schema:Person
231 sg:person.012753322153.25 schema:affiliation grid-institutes:grid.410814.8
232 schema:familyName Kanaoka
233 schema:givenName Koshiro
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012753322153.25
235 rdf:type schema:Person
236 sg:person.013050736357.32 schema:affiliation grid-institutes:None
237 schema:familyName Hirai
238 schema:givenName Kaeko
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013050736357.32
240 rdf:type schema:Person
241 sg:person.013626103316.95 schema:affiliation grid-institutes:grid.410814.8
242 schema:familyName Sugiura
243 schema:givenName Junichi
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013626103316.95
245 rdf:type schema:Person
246 sg:person.015126315422.61 schema:affiliation grid-institutes:grid.410814.8
247 schema:familyName Saito
248 schema:givenName Yoshihiko
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015126315422.61
250 rdf:type schema:Person
251 sg:person.016065413100.98 schema:affiliation grid-institutes:grid.410814.8
252 schema:familyName Keshi
253 schema:givenName Ayaka
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016065413100.98
255 rdf:type schema:Person
256 sg:person.0627605642.08 schema:affiliation grid-institutes:grid.410814.8
257 schema:familyName Nishida
258 schema:givenName Taku
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627605642.08
260 rdf:type schema:Person
261 sg:person.0645247710.78 schema:affiliation grid-institutes:grid.410814.8
262 schema:familyName Nakagawa
263 schema:givenName Hitoshi
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645247710.78
265 rdf:type schema:Person
266 sg:person.0746001440.76 schema:affiliation grid-institutes:grid.410814.8
267 schema:familyName Soeda
268 schema:givenName Tsunenari
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746001440.76
270 rdf:type schema:Person
271 sg:person.07672737335.45 schema:affiliation grid-institutes:grid.410814.8
272 schema:familyName Hashimoto
273 schema:givenName Yukihiro
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07672737335.45
275 rdf:type schema:Person
276 sg:pub.10.1007/s00380-019-01431-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1115023609
277 https://doi.org/10.1007/s00380-019-01431-z
278 rdf:type schema:CreativeWork
279 sg:pub.10.1007/s00380-021-01820-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1136236670
280 https://doi.org/10.1007/s00380-021-01820-3
281 rdf:type schema:CreativeWork
282 sg:pub.10.1007/s10840-008-9252-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1041070636
283 https://doi.org/10.1007/s10840-008-9252-z
284 rdf:type schema:CreativeWork
285 sg:pub.10.1007/s10840-013-9862-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1030643241
286 https://doi.org/10.1007/s10840-013-9862-y
287 rdf:type schema:CreativeWork
288 grid-institutes:None schema:alternateName Department of Cardiology, Nara Prefecture General Medical Center, Kashihara, Japan
289 Department of Cardiology, Nara Prefecture Seiwa Medical Center, Kashihara, Japan
290 schema:name Department of Cardiology, Nara Prefecture General Medical Center, Kashihara, Japan
291 Department of Cardiology, Nara Prefecture Seiwa Medical Center, Kashihara, Japan
292 rdf:type schema:Organization
293 grid-institutes:grid.410814.8 schema:alternateName Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan
294 schema:name Department of Cardiovascular Medicine, Nara Medical University, 840 Shijocho, 634-8522, Kashihara, Nara, Japan
295 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...