Reduced atrial conduction velocity is associated with the recurrence of atrial fibrillation after catheter ablation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-10-06

AUTHORS

Tetsuro Sato, Hidehira Fukaya, Jun Oikawa, Daiki Saito, Gen Matsuura, Yuki Arakawa, Shuhei Kobayashi, Yuki Shirakawa, Ryo Nishinarita, Ai Horiguchi, Naruya Ishizue, Jun Kishihara, Shinichi Niwano, Junya Ako

ABSTRACT

The recurrence of atrial fibrillation (AF) after catheter ablation (CA) is still an unsolved issue. Although structural remodeling is relatively well defined, the method to assess electrical remodeling of the atrium is not well established. In this study, we evaluated the relationship between atrial conduction properties and recurrence after CA for AF. One hundred six consecutive patients (66 ± 11 years old, male: 68%) who underwent CA for AF with a CARTO system from July 2016 to July 2019 were enrolled in this study. An activation map of both atria was constructed to precisely evaluate the total conduction time, distance, and conduction velocity between the earliest and latest activation sites during sinus rhythm. All parameters were compared between the patients with or without AF recurrence. Of the patients, 27 had an AF recurrence (Rec group). The left atrial (LA) conduction velocity was significantly slower in the Rec group than in the non-Rec group (101.2 ± 17.9 vs. 116.9 ± 18.0 cm/s, P < 0.01). Likewise, the right atrial (RA) conduction velocity was significantly slower in the Rec group than in the non-Rec group (81.1 ± 17.5 vs. 103.6 ± 25.4 cm/s, P < 0.01). A multivariate logistic analysis demonstrated that the LA and RA conduction velocities were independent predictors of AF recurrence, with adjusted odds ratios of 0.95 (95% confidential interval: 0.91–0.98, P < 0.01) and 0.94 (0.89–0.98, P < 0.01), respectively. In conclusion, slower conduction velocity of the atrium was associated with AF recurrence after pulmonary vein isolation. More... »

PAGES

628-637

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-021-01952-6

DOI

http://dx.doi.org/10.1007/s00380-021-01952-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1141649213

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34613425


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50 left atrial conduction velocity
51 logistic analysis
52 maps
53 method
54 multivariate logistic analysis
55 odds ratio
56 parameters
57 patients
58 predictors
59 properties
60 pulmonary vein isolation
61 ratio
62 recurrence
63 relationship
64 remodeling
65 rhythm
66 sinus rhythm
67 sites
68 slow conduction velocity
69 structural remodeling
70 study
71 system
72 time
73 total conduction time
74 unsolved issues
75 vein isolation
76 velocity
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