Association between instrumental activities of daily living with the change in left ventricular function in older patients with cardiovascular disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-03-08

AUTHORS

Hidenori Kariya, Minako Yamaoka-Tojo, Shinichi Obara, Chiharu Noda, Atsuhiko Matsunaga, Junya Ako

ABSTRACT

Left ventricular dysfunction is a pathophysiologic characteristic of heart failure. Impaired instrumental activities of daily living are associated with an elevated risk of mortality and heart failure in older adults. Nevertheless, the relationship between these activities and left ventricular function changes remains unclear. We determined whether instrumental activities of daily living are associated with subsequent left ventricular function changes in older cardiovascular disease patients. This retrospective cohort study included 383 outpatients with cardiovascular disease (74.5 ± 5.3 years, 273 males). Patients were divided according to the Frenchay activities index tertile and followed for six months after cardiovascular disease diagnosis. The left ventricular ejection fraction and annular early diastolic velocity (e′) were measured for left ventricular systolic and diastolic function, respectively, at baseline and after one year. After adjusting for confounders, changes in the left ventricular ejection fraction were not significantly different. However, changes in the e′ in the highest tertile group were significantly greater than in other groups. In the general linear model with multiple regression analysis, Frenchay activities index independently predicted the absolute change in the e′. In older cardiovascular disease patients, higher instrumental activities of daily living were associated with preserved left ventricular relaxation. More... »

PAGES

1298-1305

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-021-01812-3

DOI

http://dx.doi.org/10.1007/s00380-021-01812-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1136217036

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33683410


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