Achilles tendon thickening is associated with higher incidence of adverse cardiovascular event in patients with coronary artery disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2020-08-06

AUTHORS

Takuya Hashimoto, Yoshiyasu Minami, Kiyoshi Asakura, Masahiro Katamine, Ayami Kato, Aritomo Katsura, Toshimitsu Sato, Yusuke Muramatsu, Ryota Kakizaki, Kazuhiro Fujiyoshi, Kohki Ishida, Ryo Kameda, Kentaro Meguro, Takao Shimohama, Junya Ako

ABSTRACT

Achilles tendon thickening (ATT) is a marker of high risk for coronary artery disease (CAD). However, the association between the presence of ATT and the incidence of cardiovascular events in patients with CAD is unclear. A total of 406 consecutive patients who underwent percutaneous coronary intervention (PCI) and ATT assessment were analyzed. ATT was defined as the Achilles tendon thickness of 9 mm or more on radiography. The incidence of major adverse cardiovascular events (MACE) at 1-year was compared between patients with ATT and those without ATT. MACE included cardiac death, non-fatal myocardial infarction, stroke, target vessel revascularization (TVR), and non-TVR. ATT was found in 67 patients (16.5%). The incidence of cardiac death (3.2 vs. 0.0%, p = 0.001), TVR (12.7 vs. 4.0%, p = 0.005) and MACE (20.6 vs. 9.6%, p = 0.011) was significantly higher in the ATT group than the no ATT group. Patients with ATT had significantly higher incidence of cardiac death (5.6 vs. 0%, p < 0.001) than those without ATT even if they did not meet the diagnostic criteria of familial hypercholesterolemia. A multivariate model demonstrated that ATT was independently associated with the MACE at 1-year (Hazard ratio, 2.09; 95% Confidence Interval, 1.09–4.00, p = 0.026). The presence of ATT was independently associated with 1-year recurrence of cardiovascular events in patients with CAD undergoing PCI. Assessment of ATT might be useful for risk stratification of secondary cardiovascular events. More... »

PAGES

163-169

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-020-01679-w

DOI

http://dx.doi.org/10.1007/s00380-020-01679-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1129928240

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32761364


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34 criteria
35 death
36 diagnostic criteria
37 disease
38 events
39 familial hypercholesterolemia
40 group
41 high incidence
42 high risk
43 hypercholesterolemia
44 incidence
45 infarction
46 intervention
47 major adverse cardiovascular events
48 markers
49 model
50 multivariate model
51 myocardial infarction
52 non-fatal myocardial infarction
53 patients
54 percutaneous coronary intervention
55 presence
56 radiography
57 recurrence
58 revascularization
59 risk
60 risk stratification
61 secondary cardiovascular events
62 stratification
63 stroke
64 target vessel revascularization
65 tendon thickening
66 thickening
67 thickness
68 total
69 vessel revascularization
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