Multicenter research of bleeding risk between prasugrel and clopidogrel in Japanese patients with coronary artery disease undergoing percutaneous coronary intervention. View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-03

AUTHORS

Satoshi Tokimasa, Hideki Kitahara, Takashi Nakayama, Yoshihide Fujimoto, Taiki Shiba, Nobuaki Shikama, Mizuo Nameki, Toshiharu Himi, Ken-Ichi Fukushima, Yoshio Kobayashi

ABSTRACT

Although it has been reported that prasugrel achieves stronger antiplatelet effect and fewer cardiovascular events compared to clopidogrel in Japanese patients, there are limited data comparing the safety between the 2 dose regimens. Data from 1031 consecutive patients with coronary artery disease undergoing PCI at 5 institutions from May 2014 to April 2016, who received aspirin plus either clopidogrel (619 patients) or prasugrel (412 patients), were retrospectively analyzed. The choice of clopidogrel or prasugrel was left to the operator's discretion. Adverse events were defined as a composite of bleeding, hepatopathy, leukopenia, thrombopenia, exanthema, and major adverse cardiovascular events (MACE). MACE was defined as a composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal ischemic stroke. The average follow-up period was 143 days in the prasugrel group and 263 days in the clopidogrel group. Adverse events occurred in 34.5% of patients in the prasugrel group and in 28.6% in the clopidogrel group. Although the Kaplan-Meier curves showed lower survival rates from MACE, all-bleeding, major bleeding, minor bleeding, and adverse events, in the prasugrel group compared to the clopidogrel group (log rank test p = 0.009, p = 0.001, p = 0.012, p = 0.018, and p < 0.001, respectively), multivariate Cox-regression analyses determined prasugrel as a significant risk factor for all-bleeding, minor bleeding, and adverse events, but not for MACE and major bleeding events. Dual antiplatelet therapy with prasugrel was independently associated with minor bleeding events, but not with MACE and major bleeding events, compared to clopidogrel, after PCI in common clinical settings. More... »

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-019-01395-0

DOI

http://dx.doi.org/10.1007/s00380-019-01395-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113182343

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30944971


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Chiba University", 
          "id": "https://www.grid.ac/institutes/grid.136304.3", 
          "name": [
            "Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan. YFD02270@nifty.com."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tokimasa", 
        "givenName": "Satoshi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiba University", 
          "id": "https://www.grid.ac/institutes/grid.136304.3", 
          "name": [
            "Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kitahara", 
        "givenName": "Hideki", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiba University", 
          "id": "https://www.grid.ac/institutes/grid.136304.3", 
          "name": [
            "Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakayama", 
        "givenName": "Takashi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiba University", 
          "id": "https://www.grid.ac/institutes/grid.136304.3", 
          "name": [
            "Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan.", 
            "Department of Cardiology, Kimitsu Chuo Hospital, Chiba, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fujimoto", 
        "givenName": "Yoshihide", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiba Aoba Municipal Hospital", 
          "id": "https://www.grid.ac/institutes/grid.459433.c", 
          "name": [
            "Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan.", 
            "Department of Cardiology, Chiba Aoba Municipal Hospital, Chiba, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shiba", 
        "givenName": "Taiki", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiba Aoba Municipal Hospital", 
          "id": "https://www.grid.ac/institutes/grid.459433.c", 
          "name": [
            "Department of Cardiology, Chiba Aoba Municipal Hospital, Chiba, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shikama", 
        "givenName": "Nobuaki", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiba Kaihin Municipal Hospital", 
          "id": "https://www.grid.ac/institutes/grid.440399.3", 
          "name": [
            "Department of Cardiology, Chiba Kaihin Municipal Hospital, Chiba, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nameki", 
        "givenName": "Mizuo", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Kimitsu Chuo Hospital, Chiba, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Himi", 
        "givenName": "Toshiharu", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Matsudo City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416584.a", 
          "name": [
            "Department of Cardiology, Matsudo City Hospital, Chiba, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fukushima", 
        "givenName": "Ken-Ichi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chiba University", 
          "id": "https://www.grid.ac/institutes/grid.136304.3", 
          "name": [
            "Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kobayashi", 
        "givenName": "Yoshio", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1056/nejmoa0706482", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000755110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.clpt.6100139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006304268", 
          "https://doi.org/10.1038/sj.clpt.6100139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.clpt.6100139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006304268", 
          "https://doi.org/10.1038/sj.clpt.6100139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5551/jat.26013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006773540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jjcc.2015.07.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021337484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcin.2012.07.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022376062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12928-016-0452-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022456997", 
          "https://doi.org/10.1007/s12928-016-0452-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12928-016-0452-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022456997", 
          "https://doi.org/10.1007/s12928-016-0452-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.110.009449", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025074445"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bmt.2012.244", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028358194", 
          "https://doi.org/10.1038/bmt.2012.244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4172/2329-6607.1000162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029463679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehu523", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030609453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-14-0266", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031368573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/dmd.105.007989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038051799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0809171", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039584602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2014.12.046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049213790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-13-1482", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051285887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1409312", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051736615"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1160/th13-10-0891", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063293578"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04-03", 
    "datePublishedReg": "2019-04-03", 
    "description": "Although it has been reported that prasugrel achieves stronger antiplatelet effect and fewer cardiovascular events compared to clopidogrel in Japanese patients, there are limited data comparing the safety between the 2 dose regimens. Data from 1031 consecutive patients with coronary artery disease undergoing PCI at 5 institutions from May 2014 to April 2016, who received aspirin plus either clopidogrel (619 patients) or prasugrel (412 patients), were retrospectively analyzed. The choice of\u00a0clopidogrel or prasugrel was left to the operator's discretion. Adverse events were defined as a composite of bleeding, hepatopathy, leukopenia, thrombopenia, exanthema, and major adverse cardiovascular events (MACE). MACE was defined as a composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal ischemic stroke. The average follow-up period was 143\u00a0days in the prasugrel group and 263\u00a0days in the clopidogrel group. Adverse events occurred in 34.5% of patients in the prasugrel group and in 28.6% in the clopidogrel group. Although the Kaplan-Meier curves showed lower survival rates from MACE, all-bleeding, major bleeding, minor bleeding, and adverse events, in the prasugrel group compared to the clopidogrel group (log rank test p\u2009=\u20090.009, p\u2009=\u20090.001, p\u2009=\u20090.012, p\u2009=\u20090.018, and p\u2009<\u20090.001, respectively), multivariate Cox-regression analyses determined prasugrel as a significant risk factor for all-bleeding, minor bleeding, and adverse events, but not for MACE and major bleeding events. Dual antiplatelet therapy with prasugrel was independently associated with minor bleeding events, but not with MACE and major bleeding events, compared to clopidogrel, after PCI in common clinical settings.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00380-019-01395-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1095887", 
        "issn": [
          "0910-8327", 
          "1615-2573"
        ], 
        "name": "Heart and Vessels", 
        "type": "Periodical"
      }
    ], 
    "name": "Multicenter research of bleeding risk between prasugrel and clopidogrel in Japanese patients with coronary artery disease undergoing percutaneous coronary intervention.", 
    "productId": [
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30944971"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8511258"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00380-019-01395-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113182343"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00380-019-01395-0", 
      "https://app.dimensions.ai/details/publication/pub.1113182343"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130823_00000006.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00380-019-01395-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00380-019-01395-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00380-019-01395-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00380-019-01395-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00380-019-01395-0'


 

This table displays all metadata directly associated to this object as RDF triples.

179 TRIPLES      20 PREDICATES      41 URIs      16 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00380-019-01395-0 schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author N7cef26aedf094855a54d0a2bc87dd58f
4 schema:citation sg:pub.10.1007/s12928-016-0452-7
5 sg:pub.10.1038/bmt.2012.244
6 sg:pub.10.1038/sj.clpt.6100139
7 https://doi.org/10.1016/j.jacc.2014.12.046
8 https://doi.org/10.1016/j.jcin.2012.07.015
9 https://doi.org/10.1016/j.jjcc.2015.07.019
10 https://doi.org/10.1056/nejmoa0706482
11 https://doi.org/10.1056/nejmoa0809171
12 https://doi.org/10.1056/nejmoa1409312
13 https://doi.org/10.1093/eurheartj/ehu523
14 https://doi.org/10.1124/dmd.105.007989
15 https://doi.org/10.1160/th13-10-0891
16 https://doi.org/10.1161/circulationaha.110.009449
17 https://doi.org/10.1253/circj.cj-13-1482
18 https://doi.org/10.1253/circj.cj-14-0266
19 https://doi.org/10.4172/2329-6607.1000162
20 https://doi.org/10.5551/jat.26013
21 schema:datePublished 2019-04-03
22 schema:datePublishedReg 2019-04-03
23 schema:description Although it has been reported that prasugrel achieves stronger antiplatelet effect and fewer cardiovascular events compared to clopidogrel in Japanese patients, there are limited data comparing the safety between the 2 dose regimens. Data from 1031 consecutive patients with coronary artery disease undergoing PCI at 5 institutions from May 2014 to April 2016, who received aspirin plus either clopidogrel (619 patients) or prasugrel (412 patients), were retrospectively analyzed. The choice of clopidogrel or prasugrel was left to the operator's discretion. Adverse events were defined as a composite of bleeding, hepatopathy, leukopenia, thrombopenia, exanthema, and major adverse cardiovascular events (MACE). MACE was defined as a composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal ischemic stroke. The average follow-up period was 143 days in the prasugrel group and 263 days in the clopidogrel group. Adverse events occurred in 34.5% of patients in the prasugrel group and in 28.6% in the clopidogrel group. Although the Kaplan-Meier curves showed lower survival rates from MACE, all-bleeding, major bleeding, minor bleeding, and adverse events, in the prasugrel group compared to the clopidogrel group (log rank test p = 0.009, p = 0.001, p = 0.012, p = 0.018, and p < 0.001, respectively), multivariate Cox-regression analyses determined prasugrel as a significant risk factor for all-bleeding, minor bleeding, and adverse events, but not for MACE and major bleeding events. Dual antiplatelet therapy with prasugrel was independently associated with minor bleeding events, but not with MACE and major bleeding events, compared to clopidogrel, after PCI in common clinical settings.
24 schema:genre research_article
25 schema:inLanguage en
26 schema:isAccessibleForFree false
27 schema:isPartOf sg:journal.1095887
28 schema:name Multicenter research of bleeding risk between prasugrel and clopidogrel in Japanese patients with coronary artery disease undergoing percutaneous coronary intervention.
29 schema:productId Nb6e3b10c66a94a9ea22dd93bffbb2bbc
30 Ncbee0f28a63e449e97aa6f322b71bb5c
31 Ncf29854d034b4cc7ab76c4dda39cef94
32 Nd2087049aa3b4afca2b1d73eface274f
33 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113182343
34 https://doi.org/10.1007/s00380-019-01395-0
35 schema:sdDatePublished 2019-04-11T13:59
36 schema:sdLicense https://scigraph.springernature.com/explorer/license/
37 schema:sdPublisher N8a26a223e673426c918780c6c64267bc
38 schema:url http://link.springer.com/10.1007/s00380-019-01395-0
39 sgo:license sg:explorer/license/
40 sgo:sdDataset articles
41 rdf:type schema:ScholarlyArticle
42 N0fd5a4c55fef49f5ba735ddd972ec708 rdf:first N3c98fd19e4d14708b4ef17eea0f6d7ea
43 rdf:rest Nb66c37d09c384e5fa8d932fdcce564f6
44 N1be09121ab0849b8b9ab5af80289452f schema:affiliation https://www.grid.ac/institutes/grid.416584.a
45 schema:familyName Fukushima
46 schema:givenName Ken-Ichi
47 rdf:type schema:Person
48 N34242f58042e46e5b540b6fbaa2e159a rdf:first N906d6c06f5154594a156e296d3f349ec
49 rdf:rest N6a910dfbd6784f75b406976dcd5c082f
50 N38f7f8150cbf461e8c2d411e0c5a07b7 rdf:first Nbc225408b95a4f9d9d8b71f5d6573d00
51 rdf:rest rdf:nil
52 N3c98fd19e4d14708b4ef17eea0f6d7ea schema:affiliation N764dbd0900554c56a17cd9ebee043413
53 schema:familyName Himi
54 schema:givenName Toshiharu
55 rdf:type schema:Person
56 N40f2e1e67c934813aee812ef015339c2 schema:affiliation https://www.grid.ac/institutes/grid.440399.3
57 schema:familyName Nameki
58 schema:givenName Mizuo
59 rdf:type schema:Person
60 N56dd6f660da041b98453050b0e95cb95 schema:affiliation https://www.grid.ac/institutes/grid.136304.3
61 schema:familyName Tokimasa
62 schema:givenName Satoshi
63 rdf:type schema:Person
64 N5dd568b66035436a8ffef7096be89e4a rdf:first N40f2e1e67c934813aee812ef015339c2
65 rdf:rest N0fd5a4c55fef49f5ba735ddd972ec708
66 N5ed8b86fb08f46619a396ebcf4d60fd2 rdf:first Nf3fbf9398a364a0694fb9a0db58984ae
67 rdf:rest N5dd568b66035436a8ffef7096be89e4a
68 N6a910dfbd6784f75b406976dcd5c082f rdf:first Nfce586fde3e844589b243af679d75d0e
69 rdf:rest N7fb3cdb3193349a587a9b972f960b1cf
70 N764dbd0900554c56a17cd9ebee043413 schema:name Department of Cardiology, Kimitsu Chuo Hospital, Chiba, Japan.
71 rdf:type schema:Organization
72 N7cef26aedf094855a54d0a2bc87dd58f rdf:first N56dd6f660da041b98453050b0e95cb95
73 rdf:rest N34242f58042e46e5b540b6fbaa2e159a
74 N7fb3cdb3193349a587a9b972f960b1cf rdf:first Na907c8d8a3aa445786abf2d6fedfdc68
75 rdf:rest Nbde3c2d684964dc6bf99a78621138341
76 N8a26a223e673426c918780c6c64267bc schema:name Springer Nature - SN SciGraph project
77 rdf:type schema:Organization
78 N906d6c06f5154594a156e296d3f349ec schema:affiliation https://www.grid.ac/institutes/grid.136304.3
79 schema:familyName Kitahara
80 schema:givenName Hideki
81 rdf:type schema:Person
82 N97a46f99d1324c538b99378c7cad66c7 schema:affiliation https://www.grid.ac/institutes/grid.459433.c
83 schema:familyName Shiba
84 schema:givenName Taiki
85 rdf:type schema:Person
86 Na907c8d8a3aa445786abf2d6fedfdc68 schema:affiliation https://www.grid.ac/institutes/grid.136304.3
87 schema:familyName Fujimoto
88 schema:givenName Yoshihide
89 rdf:type schema:Person
90 Nb66c37d09c384e5fa8d932fdcce564f6 rdf:first N1be09121ab0849b8b9ab5af80289452f
91 rdf:rest N38f7f8150cbf461e8c2d411e0c5a07b7
92 Nb6e3b10c66a94a9ea22dd93bffbb2bbc schema:name pubmed_id
93 schema:value 30944971
94 rdf:type schema:PropertyValue
95 Nbc225408b95a4f9d9d8b71f5d6573d00 schema:affiliation https://www.grid.ac/institutes/grid.136304.3
96 schema:familyName Kobayashi
97 schema:givenName Yoshio
98 rdf:type schema:Person
99 Nbde3c2d684964dc6bf99a78621138341 rdf:first N97a46f99d1324c538b99378c7cad66c7
100 rdf:rest N5ed8b86fb08f46619a396ebcf4d60fd2
101 Ncbee0f28a63e449e97aa6f322b71bb5c schema:name dimensions_id
102 schema:value pub.1113182343
103 rdf:type schema:PropertyValue
104 Ncf29854d034b4cc7ab76c4dda39cef94 schema:name doi
105 schema:value 10.1007/s00380-019-01395-0
106 rdf:type schema:PropertyValue
107 Nd2087049aa3b4afca2b1d73eface274f schema:name nlm_unique_id
108 schema:value 8511258
109 rdf:type schema:PropertyValue
110 Nf3fbf9398a364a0694fb9a0db58984ae schema:affiliation https://www.grid.ac/institutes/grid.459433.c
111 schema:familyName Shikama
112 schema:givenName Nobuaki
113 rdf:type schema:Person
114 Nfce586fde3e844589b243af679d75d0e schema:affiliation https://www.grid.ac/institutes/grid.136304.3
115 schema:familyName Nakayama
116 schema:givenName Takashi
117 rdf:type schema:Person
118 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
119 schema:name Medical and Health Sciences
120 rdf:type schema:DefinedTerm
121 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
122 schema:name Cardiorespiratory Medicine and Haematology
123 rdf:type schema:DefinedTerm
124 sg:journal.1095887 schema:issn 0910-8327
125 1615-2573
126 schema:name Heart and Vessels
127 rdf:type schema:Periodical
128 sg:pub.10.1007/s12928-016-0452-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022456997
129 https://doi.org/10.1007/s12928-016-0452-7
130 rdf:type schema:CreativeWork
131 sg:pub.10.1038/bmt.2012.244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028358194
132 https://doi.org/10.1038/bmt.2012.244
133 rdf:type schema:CreativeWork
134 sg:pub.10.1038/sj.clpt.6100139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006304268
135 https://doi.org/10.1038/sj.clpt.6100139
136 rdf:type schema:CreativeWork
137 https://doi.org/10.1016/j.jacc.2014.12.046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049213790
138 rdf:type schema:CreativeWork
139 https://doi.org/10.1016/j.jcin.2012.07.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022376062
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1016/j.jjcc.2015.07.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021337484
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1056/nejmoa0706482 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000755110
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1056/nejmoa0809171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039584602
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1056/nejmoa1409312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051736615
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1093/eurheartj/ehu523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030609453
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1124/dmd.105.007989 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038051799
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1160/th13-10-0891 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063293578
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1161/circulationaha.110.009449 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025074445
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1253/circj.cj-13-1482 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051285887
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1253/circj.cj-14-0266 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031368573
160 rdf:type schema:CreativeWork
161 https://doi.org/10.4172/2329-6607.1000162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029463679
162 rdf:type schema:CreativeWork
163 https://doi.org/10.5551/jat.26013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006773540
164 rdf:type schema:CreativeWork
165 https://www.grid.ac/institutes/grid.136304.3 schema:alternateName Chiba University
166 schema:name Department of Cardiology, Kimitsu Chuo Hospital, Chiba, Japan.
167 Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan.
168 Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan. YFD02270@nifty.com.
169 rdf:type schema:Organization
170 https://www.grid.ac/institutes/grid.416584.a schema:alternateName Matsudo City Hospital
171 schema:name Department of Cardiology, Matsudo City Hospital, Chiba, Japan.
172 rdf:type schema:Organization
173 https://www.grid.ac/institutes/grid.440399.3 schema:alternateName Chiba Kaihin Municipal Hospital
174 schema:name Department of Cardiology, Chiba Kaihin Municipal Hospital, Chiba, Japan.
175 rdf:type schema:Organization
176 https://www.grid.ac/institutes/grid.459433.c schema:alternateName Chiba Aoba Municipal Hospital
177 schema:name Department of Cardiology, Chiba Aoba Municipal Hospital, Chiba, Japan.
178 Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan.
179 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...