The perfusion index is a useful screening tool for peripheral artery disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Hiroshi Okada, Muhei Tanaka, Takashi Yasuda, Tadaaki Kamitani, Hisahiro Norikae, Tetsuya Fujita, Takashi Nishi, Hirokazu Oyamada, Tetsuro Yamane, Michiaki Fukui

ABSTRACT

The number of people with peripheral artery disease (PAD) has been increasing globally; therefore, it is important to explore more options to screen patients who are at a risk of developing PAD. The perfusion index (PI) represents the degree of circulation through the peripheral tissues and is measured noninvasively. We investigated the correlation between the PI and ankle-brachial index (ABI) to explore whether the PI could be used a screening tool for PAD. This cross-sectional study included 390 patients. We measured the ABI and PI for all patients. The median ABI value was 1.06 (0.92-1.13); the PI was 1.7% (0.9-3.5). The PI was higher in men than in women (P < 0.0001). The PI was positively correlated with the estimated glomerular filtration rate and ABI in both men and women. The sensitivity and specificity of the PI to predict PAD (ABI ≤0.9) were 90.0% and 80.3%, respectively, and the cutoff PI value was 1.5% in men. The sensitivity and specificity of the PI to predict PAD were 82.1% and 79.2%, respectively, and the cutoff PI value was 1.1% in women. PI could be a reliable screening tool for diagnosing PAD because it does not restrict the patient's mobility, can be completed in a short time period, and is associated with reduced costs. More... »

PAGES

583-589

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-018-1276-4

DOI

http://dx.doi.org/10.1007/s00380-018-1276-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107372145

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30284017


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