Different diuretic properties between tolvaptan and furosemide in congestive heart failure patients with diuretic resistance and renal impairment: a subanalysis ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-09-26

AUTHORS

Yuki Ikeda, Takayuki Inomata, Keisuke Kida, Yugo Shibagaki, Naoki Sato, Tohru Izumi, Junya Ako, Kanagawa Aquaresis Investigators

ABSTRACT

We attempted to identify the difference in diuretic properties between tolvaptan (TLV) and furosemide (FUR) in congestive heart failure (CHF) patients with loop diuretic resistance and renal impairment. We investigated 81 CHF patients with loop diuretic treatment and renal impairment included in t he Kanagawa Aquaresis Investigators Trial of Tolvaptan on Heart Failure Patients with Renal Impairment (K-STAR). Predictive baseline factors and their changes during treatment periods were analyzed for correlation with percentage change in urine volume (%ΔUV) after additive introduction of TLV or increasing doses of FUR. Higher urine osmolality at baseline (β = 0.355; p = 0.033) in the TLV group and a lower ratio of blood urea nitrogen to serum creatinine (BUN/Cr, β = − 0.405; p = 0.020) in the FUR group were predictive of higher %ΔUV. Higher Δfree-water clearance (β = 0.667; p < 0.0001) in the TLV group, and higher %ΔBUN/Cr (β = 0.344; p = 0.030), higher %Δurine sodium concentration (β = 0.337; p = 0.037), and lower %Δstroke volume (β = − 0.390; p = 0.017) in the FUR group were correlated with %ΔUV. In conclusion, baseline urine osmolality and change in free-water clearance with additive introduction of TLV and a changing ratio of BUN/Cr with increasing doses of FUR were identified as key clinical parameters related to diuretic response.Trial registration UMIN000009201. More... »

PAGES

442-451

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-018-1270-x

DOI

http://dx.doi.org/10.1007/s00380-018-1270-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107260483

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30259172


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antidiuretic Hormone Receptor Antagonists", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Creatinine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Resistance", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Furosemide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Failure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renal Insufficiency", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sodium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sodium Potassium Chloride Symporter Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tolvaptan", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ikeda", 
        "givenName": "Yuki", 
        "id": "sg:person.01247203074.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247203074.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kitasato University Kitasato Institute Hospital, 5-9-1 Shirokane, Minato-ku, 108-8642, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.415395.f", 
          "name": [
            "Department of Cardiovascular Medicine, Kitasato University Kitasato Institute Hospital, 5-9-1 Shirokane, Minato-ku, 108-8642, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inomata", 
        "givenName": "Takayuki", 
        "id": "sg:person.01257427322.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257427322.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412764.2", 
          "name": [
            "Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kida", 
        "givenName": "Keisuke", 
        "id": "sg:person.01105230756.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105230756.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412764.2", 
          "name": [
            "Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shibagaki", 
        "givenName": "Yugo", 
        "id": "sg:person.01333704044.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333704044.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Internal Medicine and Cardiology, Nippon Medical School Musashi-Kosugi Hospital, Kawasaki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.459842.6", 
          "name": [
            "Internal Medicine and Cardiology, Nippon Medical School Musashi-Kosugi Hospital, Kawasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sato", 
        "givenName": "Naoki", 
        "id": "sg:person.013447710172.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013447710172.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Niigata Minami Hospital, Niigata, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Niigata Minami Hospital, Niigata, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Izumi", 
        "givenName": "Tohru", 
        "id": "sg:person.0672551771.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672551771.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410786.c", 
          "name": [
            "Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ako", 
        "givenName": "Junya", 
        "id": "sg:person.0744472011.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744472011.56"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Kanagawa Aquaresis Investigators", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s40256-015-0121-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041134678", 
          "https://doi.org/10.1007/s40256-015-0121-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-012-9354-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050342387", 
          "https://doi.org/10.1007/s10741-012-9354-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrcardio.2014.215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034261046", 
          "https://doi.org/10.1038/nrcardio.2014.215"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-09-26", 
    "datePublishedReg": "2018-09-26", 
    "description": "We attempted to identify the difference in diuretic properties between tolvaptan (TLV) and furosemide (FUR) in congestive heart failure (CHF) patients with loop diuretic resistance and renal impairment. We investigated 81 CHF patients with loop diuretic treatment and renal impairment included in t he Kanagawa Aquaresis Investigators Trial of Tolvaptan on Heart Failure Patients with Renal Impairment (K-STAR). Predictive baseline factors and their changes during treatment periods were analyzed for correlation with percentage change in urine volume (%\u0394UV) after additive introduction of TLV or increasing doses of FUR. Higher urine osmolality at baseline (\u03b2\u2009=\u20090.355; p\u2009=\u20090.033) in the TLV group and a lower ratio of blood urea nitrogen to serum creatinine (BUN/Cr, \u03b2\u2009=\u2009\u2212\u20090.405; p\u2009=\u20090.020) in the FUR group were predictive of higher %\u0394UV. Higher \u0394free-water clearance (\u03b2\u2009=\u20090.667; p\u2009<\u20090.0001) in the TLV group, and higher %\u0394BUN/Cr (\u03b2\u2009=\u20090.344; p\u2009=\u20090.030), higher %\u0394urine sodium concentration (\u03b2\u2009=\u20090.337; p\u2009=\u20090.037), and lower %\u0394stroke volume (\u03b2\u2009=\u2009\u2212\u20090.390; p\u2009=\u20090.017) in the FUR group were correlated with %\u0394UV. In conclusion, baseline urine osmolality and change in free-water clearance with additive introduction of TLV and a changing ratio of BUN/Cr with increasing doses of FUR were identified as key clinical parameters related to diuretic response.Trial registration UMIN000009201.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00380-018-1270-x", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1095887", 
        "issn": [
          "0910-8327", 
          "1615-2573"
        ], 
        "name": "Heart and Vessels", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "34"
      }
    ], 
    "keywords": [
      "heart failure patients", 
      "congestive heart failure patients", 
      "renal impairment", 
      "doses of furosemide", 
      "failure patients", 
      "diuretic resistance", 
      "TLV group", 
      "fur group", 
      "urine osmolality", 
      "diuretic properties", 
      "loop diuretic resistance", 
      "loop diuretic treatment", 
      "predictive baseline factors", 
      "baseline urine osmolality", 
      "BUN/Cr", 
      "free water clearance", 
      "blood urea nitrogen", 
      "key clinical parameters", 
      "high urine osmolality", 
      "CHF patients", 
      "diuretic treatment", 
      "baseline factors", 
      "urine volume", 
      "clinical parameters", 
      "diuretic response", 
      "treatment period", 
      "tolvaptan", 
      "urea nitrogen", 
      "patients", 
      "furosemide", 
      "percentage change", 
      "impairment", 
      "sodium concentration", 
      "doses", 
      "clearance", 
      "osmolality", 
      "group", 
      "subanalysis", 
      "creatinine", 
      "trials", 
      "baseline", 
      "treatment", 
      "low ratio", 
      "changes", 
      "conclusion", 
      "resistance", 
      "volume", 
      "\u0394UV", 
      "response", 
      "period", 
      "factors", 
      "differences", 
      "ratio", 
      "correlation", 
      "concentration", 
      "introduction", 
      "Cr", 
      "parameters", 
      "properties", 
      "nitrogen", 
      "additive introduction", 
      "K stars"
    ], 
    "name": "Different diuretic properties between tolvaptan and furosemide in congestive heart failure patients with diuretic resistance and renal impairment: a subanalysis of the K-STAR", 
    "pagination": "442-451", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1107260483"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00380-018-1270-x"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30259172"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00380-018-1270-x", 
      "https://app.dimensions.ai/details/publication/pub.1107260483"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T16:03", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_791.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00380-018-1270-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00380-018-1270-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00380-018-1270-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00380-018-1270-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00380-018-1270-x'


 

This table displays all metadata directly associated to this object as RDF triples.

271 TRIPLES      21 PREDICATES      109 URIs      98 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00380-018-1270-x schema:about N026f211e02134b0d84dead9147cabd31
2 N2a8fac4682d5455ba736389d3927d519
3 N2d6d65300ae74699a10f23f31be6385f
4 N396925a9d8274658aa7c8063a2d125cb
5 N5519515d17524315af288c2b7188e07f
6 N60d5ef775e7048daadff81bbe983860e
7 N64bbe904c79247ebb69c7a52664bf447
8 N73f824ab95584ddc95826c17dc553f95
9 N7743149635274a60991db4343405e878
10 N8506427c692648548b6e94dca7b26b3a
11 N8e7b9e95c1944eb8b273bcefbf267320
12 N910472f31ef74967a193cdcf3bd64529
13 N9692c329de1340eeb61210b0d905893e
14 N9c2104e2d14d44089e8724decd16f529
15 Na7106810d0ca42829aa42d32c5e92d13
16 Nb3cc7ce7fb4049149aa99f4529bd984d
17 Nd442fba9d5c248e19d44a7eee58aecca
18 Ndfd6db86607441209f31b9795c6c8dd5
19 Ne69655a72dcc4bff9b911dda1ccb04a8
20 anzsrc-for:11
21 anzsrc-for:1102
22 schema:author Nc813abc9abc646658ebb1cd14eecd939
23 schema:citation sg:pub.10.1007/s10741-012-9354-7
24 sg:pub.10.1007/s40256-015-0121-8
25 sg:pub.10.1038/nrcardio.2014.215
26 schema:datePublished 2018-09-26
27 schema:datePublishedReg 2018-09-26
28 schema:description We attempted to identify the difference in diuretic properties between tolvaptan (TLV) and furosemide (FUR) in congestive heart failure (CHF) patients with loop diuretic resistance and renal impairment. We investigated 81 CHF patients with loop diuretic treatment and renal impairment included in t he Kanagawa Aquaresis Investigators Trial of Tolvaptan on Heart Failure Patients with Renal Impairment (K-STAR). Predictive baseline factors and their changes during treatment periods were analyzed for correlation with percentage change in urine volume (%ΔUV) after additive introduction of TLV or increasing doses of FUR. Higher urine osmolality at baseline (β = 0.355; p = 0.033) in the TLV group and a lower ratio of blood urea nitrogen to serum creatinine (BUN/Cr, β = − 0.405; p = 0.020) in the FUR group were predictive of higher %ΔUV. Higher Δfree-water clearance (β = 0.667; p < 0.0001) in the TLV group, and higher %ΔBUN/Cr (β = 0.344; p = 0.030), higher %Δurine sodium concentration (β = 0.337; p = 0.037), and lower %Δstroke volume (β = − 0.390; p = 0.017) in the FUR group were correlated with %ΔUV. In conclusion, baseline urine osmolality and change in free-water clearance with additive introduction of TLV and a changing ratio of BUN/Cr with increasing doses of FUR were identified as key clinical parameters related to diuretic response.Trial registration UMIN000009201.
29 schema:genre article
30 schema:isAccessibleForFree false
31 schema:isPartOf N37d1b8a01f964fdeaa6d1930d3ea2975
32 Nc1283f6081be4a439fe86eef48a8feb7
33 sg:journal.1095887
34 schema:keywords BUN/Cr
35 CHF patients
36 Cr
37 K stars
38 TLV group
39 additive introduction
40 baseline
41 baseline factors
42 baseline urine osmolality
43 blood urea nitrogen
44 changes
45 clearance
46 clinical parameters
47 concentration
48 conclusion
49 congestive heart failure patients
50 correlation
51 creatinine
52 differences
53 diuretic properties
54 diuretic resistance
55 diuretic response
56 diuretic treatment
57 doses
58 doses of furosemide
59 factors
60 failure patients
61 free water clearance
62 fur group
63 furosemide
64 group
65 heart failure patients
66 high urine osmolality
67 impairment
68 introduction
69 key clinical parameters
70 loop diuretic resistance
71 loop diuretic treatment
72 low ratio
73 nitrogen
74 osmolality
75 parameters
76 patients
77 percentage change
78 period
79 predictive baseline factors
80 properties
81 ratio
82 renal impairment
83 resistance
84 response
85 sodium concentration
86 subanalysis
87 tolvaptan
88 treatment
89 treatment period
90 trials
91 urea nitrogen
92 urine osmolality
93 urine volume
94 volume
95 ΔUV
96 schema:name Different diuretic properties between tolvaptan and furosemide in congestive heart failure patients with diuretic resistance and renal impairment: a subanalysis of the K-STAR
97 schema:pagination 442-451
98 schema:productId N5b6d1f4ceeaa465594c867ecb1b0ad4f
99 Nc6747cb964d54664ab3441567df548b5
100 Neda44d0858ab4aa5af5d6228bbc2e87a
101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107260483
102 https://doi.org/10.1007/s00380-018-1270-x
103 schema:sdDatePublished 2022-09-02T16:03
104 schema:sdLicense https://scigraph.springernature.com/explorer/license/
105 schema:sdPublisher Nf9b8758b3cb64dae8003a831274b0832
106 schema:url https://doi.org/10.1007/s00380-018-1270-x
107 sgo:license sg:explorer/license/
108 sgo:sdDataset articles
109 rdf:type schema:ScholarlyArticle
110 N026f211e02134b0d84dead9147cabd31 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Male
112 rdf:type schema:DefinedTerm
113 N2a8fac4682d5455ba736389d3927d519 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Biomarkers
115 rdf:type schema:DefinedTerm
116 N2d6d65300ae74699a10f23f31be6385f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Time Factors
118 rdf:type schema:DefinedTerm
119 N37d1b8a01f964fdeaa6d1930d3ea2975 schema:issueNumber 3
120 rdf:type schema:PublicationIssue
121 N396925a9d8274658aa7c8063a2d125cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Tolvaptan
123 rdf:type schema:DefinedTerm
124 N494ecf6b4070436b823a28e44af9f27d schema:familyName Kanagawa Aquaresis Investigators
125 rdf:type schema:Person
126 N5519515d17524315af288c2b7188e07f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Follow-Up Studies
128 rdf:type schema:DefinedTerm
129 N5b6d1f4ceeaa465594c867ecb1b0ad4f schema:name doi
130 schema:value 10.1007/s00380-018-1270-x
131 rdf:type schema:PropertyValue
132 N60d5ef775e7048daadff81bbe983860e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Aged, 80 and over
134 rdf:type schema:DefinedTerm
135 N64bbe904c79247ebb69c7a52664bf447 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Heart Failure
137 rdf:type schema:DefinedTerm
138 N6fda850b37da4f3fb9796c45a8276249 rdf:first sg:person.0744472011.56
139 rdf:rest Na2cfe9efa1474265bf9b818cb252f05f
140 N73f824ab95584ddc95826c17dc553f95 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Aged
142 rdf:type schema:DefinedTerm
143 N76a7688e18834f1ab37eaf10a31b508d rdf:first sg:person.013447710172.90
144 rdf:rest N9092100d498d4894a66e0e795d16d5ff
145 N7743149635274a60991db4343405e878 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Sodium
147 rdf:type schema:DefinedTerm
148 N8506427c692648548b6e94dca7b26b3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Antidiuretic Hormone Receptor Antagonists
150 rdf:type schema:DefinedTerm
151 N8e7b9e95c1944eb8b273bcefbf267320 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Sodium Potassium Chloride Symporter Inhibitors
153 rdf:type schema:DefinedTerm
154 N9092100d498d4894a66e0e795d16d5ff rdf:first sg:person.0672551771.07
155 rdf:rest N6fda850b37da4f3fb9796c45a8276249
156 N910472f31ef74967a193cdcf3bd64529 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Renal Insufficiency
158 rdf:type schema:DefinedTerm
159 N957628ed31674d45b0772985125f69e0 rdf:first sg:person.01105230756.21
160 rdf:rest Nd063215842e447da8fd3816b2cfa14f2
161 N9692c329de1340eeb61210b0d905893e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Drug Resistance
163 rdf:type schema:DefinedTerm
164 N9c2104e2d14d44089e8724decd16f529 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Furosemide
166 rdf:type schema:DefinedTerm
167 Na2cfe9efa1474265bf9b818cb252f05f rdf:first N494ecf6b4070436b823a28e44af9f27d
168 rdf:rest rdf:nil
169 Na7106810d0ca42829aa42d32c5e92d13 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Prospective Studies
171 rdf:type schema:DefinedTerm
172 Nb3cc7ce7fb4049149aa99f4529bd984d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Treatment Outcome
174 rdf:type schema:DefinedTerm
175 Nc1283f6081be4a439fe86eef48a8feb7 schema:volumeNumber 34
176 rdf:type schema:PublicationVolume
177 Nc6747cb964d54664ab3441567df548b5 schema:name dimensions_id
178 schema:value pub.1107260483
179 rdf:type schema:PropertyValue
180 Nc813abc9abc646658ebb1cd14eecd939 rdf:first sg:person.01247203074.53
181 rdf:rest Nf93c18744a7c41c4a00fde80c5a14d4d
182 Nd063215842e447da8fd3816b2cfa14f2 rdf:first sg:person.01333704044.43
183 rdf:rest N76a7688e18834f1ab37eaf10a31b508d
184 Nd442fba9d5c248e19d44a7eee58aecca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Creatinine
186 rdf:type schema:DefinedTerm
187 Ndfd6db86607441209f31b9795c6c8dd5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Female
189 rdf:type schema:DefinedTerm
190 Ne69655a72dcc4bff9b911dda1ccb04a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Humans
192 rdf:type schema:DefinedTerm
193 Neda44d0858ab4aa5af5d6228bbc2e87a schema:name pubmed_id
194 schema:value 30259172
195 rdf:type schema:PropertyValue
196 Nf93c18744a7c41c4a00fde80c5a14d4d rdf:first sg:person.01257427322.82
197 rdf:rest N957628ed31674d45b0772985125f69e0
198 Nf9b8758b3cb64dae8003a831274b0832 schema:name Springer Nature - SN SciGraph project
199 rdf:type schema:Organization
200 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
201 schema:name Medical and Health Sciences
202 rdf:type schema:DefinedTerm
203 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
204 schema:name Cardiorespiratory Medicine and Haematology
205 rdf:type schema:DefinedTerm
206 sg:journal.1095887 schema:issn 0910-8327
207 1615-2573
208 schema:name Heart and Vessels
209 schema:publisher Springer Nature
210 rdf:type schema:Periodical
211 sg:person.01105230756.21 schema:affiliation grid-institutes:grid.412764.2
212 schema:familyName Kida
213 schema:givenName Keisuke
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105230756.21
215 rdf:type schema:Person
216 sg:person.01247203074.53 schema:affiliation grid-institutes:grid.410786.c
217 schema:familyName Ikeda
218 schema:givenName Yuki
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247203074.53
220 rdf:type schema:Person
221 sg:person.01257427322.82 schema:affiliation grid-institutes:grid.415395.f
222 schema:familyName Inomata
223 schema:givenName Takayuki
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257427322.82
225 rdf:type schema:Person
226 sg:person.01333704044.43 schema:affiliation grid-institutes:grid.412764.2
227 schema:familyName Shibagaki
228 schema:givenName Yugo
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333704044.43
230 rdf:type schema:Person
231 sg:person.013447710172.90 schema:affiliation grid-institutes:grid.459842.6
232 schema:familyName Sato
233 schema:givenName Naoki
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013447710172.90
235 rdf:type schema:Person
236 sg:person.0672551771.07 schema:affiliation grid-institutes:None
237 schema:familyName Izumi
238 schema:givenName Tohru
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672551771.07
240 rdf:type schema:Person
241 sg:person.0744472011.56 schema:affiliation grid-institutes:grid.410786.c
242 schema:familyName Ako
243 schema:givenName Junya
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744472011.56
245 rdf:type schema:Person
246 sg:pub.10.1007/s10741-012-9354-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050342387
247 https://doi.org/10.1007/s10741-012-9354-7
248 rdf:type schema:CreativeWork
249 sg:pub.10.1007/s40256-015-0121-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041134678
250 https://doi.org/10.1007/s40256-015-0121-8
251 rdf:type schema:CreativeWork
252 sg:pub.10.1038/nrcardio.2014.215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034261046
253 https://doi.org/10.1038/nrcardio.2014.215
254 rdf:type schema:CreativeWork
255 grid-institutes:None schema:alternateName Niigata Minami Hospital, Niigata, Japan
256 schema:name Niigata Minami Hospital, Niigata, Japan
257 rdf:type schema:Organization
258 grid-institutes:grid.410786.c schema:alternateName Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan
259 schema:name Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan
260 rdf:type schema:Organization
261 grid-institutes:grid.412764.2 schema:alternateName Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
262 Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
263 schema:name Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
264 Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
265 rdf:type schema:Organization
266 grid-institutes:grid.415395.f schema:alternateName Department of Cardiovascular Medicine, Kitasato University Kitasato Institute Hospital, 5-9-1 Shirokane, Minato-ku, 108-8642, Tokyo, Japan
267 schema:name Department of Cardiovascular Medicine, Kitasato University Kitasato Institute Hospital, 5-9-1 Shirokane, Minato-ku, 108-8642, Tokyo, Japan
268 rdf:type schema:Organization
269 grid-institutes:grid.459842.6 schema:alternateName Internal Medicine and Cardiology, Nippon Medical School Musashi-Kosugi Hospital, Kawasaki, Japan
270 schema:name Internal Medicine and Cardiology, Nippon Medical School Musashi-Kosugi Hospital, Kawasaki, Japan
271 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...