Specific periodontopathic bacterial infection affects hypertension in male cardiovascular disease patients View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-02

AUTHORS

Norio Aoyama, Jun-ichi Suzuki, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Issei Komuro, Masato Minabe, Yuichi Izumi, Mitsuaki Isobe

ABSTRACT

Hypertension (HT) is a systemic disorder that results in the decline of quality of life and death. While patients with periodontitis are at a high risk of HT, little causal information has been provided to date. To clarify the relationship, periodontopathic bacterial infection in cardiovascular patients with or without HT was evaluated. The subjects were patients with (n = 412) or without (n = 199) HT who attended Tokyo Medical and Dental University hospital. Blood examinations and periodontal measurements were performed. Three periodontopathic bacteria existence and antibody titers were evaluated. We found that specific periodontopathic bacteria, Aggregatibacter actinomycetemcomitans and Prevotella intermedia, were highly detected in male subjects with HT compared to non-HT subjects, while they were comparable in the female patients. Mean probing pocket depth of elderly male patients with HT was higher compared to non-HT patients. The rates of obesity, dyslipidemia, and diabetes showed partial statistical difference between the two groups. Specific periodontopathic bacterial infection may affect HT in male cardiovascular patients. More... »

PAGES

198-204

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-017-1042-z

DOI

http://dx.doi.org/10.1007/s00380-017-1042-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091197582

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28803419


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacterial Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cause of Death", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Japan", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Periodontitis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality of Life", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kanagawa Dental University", 
          "id": "https://www.grid.ac/institutes/grid.462431.6", 
          "name": [
            "Division of Periodontology, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaokacho, 238-8580, Yokosuka, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aoyama", 
        "givenName": "Norio", 
        "id": "sg:person.01320016400.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320016400.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Medical and Dental University", 
          "id": "https://www.grid.ac/institutes/grid.265073.5", 
          "name": [
            "Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
            "Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8549, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Jun-ichi", 
        "id": "sg:person.0772072503.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772072503.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumagai", 
        "givenName": "Hidetoshi", 
        "id": "sg:person.0736053075.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736053075.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ikeda", 
        "givenName": "Yuichi", 
        "id": "sg:person.012757402652.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012757402652.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akazawa", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01150350762.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150350762.93"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Komuro", 
        "givenName": "Issei", 
        "id": "sg:person.01012024207.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012024207.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kanagawa Dental University", 
          "id": "https://www.grid.ac/institutes/grid.462431.6", 
          "name": [
            "Division of Periodontology, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaokacho, 238-8580, Yokosuka, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Minabe", 
        "givenName": "Masato", 
        "id": "sg:person.01344051345.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344051345.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Medical and Dental University", 
          "id": "https://www.grid.ac/institutes/grid.265073.5", 
          "name": [
            "Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8549, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Izumi", 
        "givenName": "Yuichi", 
        "id": "sg:person.0656160415.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656160415.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Medical and Dental University", 
          "id": "https://www.grid.ac/institutes/grid.265073.5", 
          "name": [
            "Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8549, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Isobe", 
        "givenName": "Mitsuaki", 
        "id": "sg:person.01266743300.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266743300.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.ejvs.2007.08.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001756836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0095521", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002757265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.atherosclerosis.2011.04.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003892934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2008.05.057", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004611762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.306.6879.688", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006093807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0022034515602693", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007211019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0022034515602693", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007211019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11606-008-0787-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009231770", 
          "https://doi.org/10.1007/s11606-008-0787-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)67728-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009590961"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)67728-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009590961"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31825719f3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010818306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31825719f3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010818306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31825719f3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010818306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/suq001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011099933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/suq001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011099933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.12659/msm.882050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012138938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ahj.2016.07.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014583077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j..2003.com122.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020776384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0757.2006.00178.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026692366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1743-6109.2008.01141.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027716609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa063186", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029455137"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-8703(99)70312-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035902375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1536/ihj.53.209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036075512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0928-8244(03)00224-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036815923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199511233332106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051075780"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/md.0000000000002067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051878439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/md.0000000000002067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051878439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31828124ad", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052501077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31828124ad", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052501077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.284.11.1406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052920186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ahj.2007.06.037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053497239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/met.2016.0018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059299044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/postgradmedj-2016-134279", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062821399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/postgradmedj-2016-134279", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062821399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1902/annals.2001.6.1.9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068728336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1902/annals.2001.6.1.9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068728336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1573403x10666140416094901", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069208019"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-02", 
    "datePublishedReg": "2018-02-01", 
    "description": "Hypertension (HT) is a systemic disorder that results in the decline of quality of life and death. While patients with periodontitis are at a high risk of HT, little causal information has been provided to date. To clarify the relationship, periodontopathic bacterial infection in cardiovascular patients with or without HT was evaluated. The subjects were patients with (n\u00a0=\u00a0412) or without (n\u00a0=\u00a0199) HT who attended Tokyo Medical and Dental University hospital. Blood examinations and periodontal measurements were performed. Three periodontopathic bacteria existence and antibody titers were evaluated. We found that specific periodontopathic bacteria, Aggregatibacter actinomycetemcomitans and Prevotella intermedia, were highly detected in male subjects with HT compared to non-HT subjects, while they were comparable in the female patients. Mean probing pocket depth of elderly male patients with HT was higher compared to non-HT patients. The rates of obesity, dyslipidemia, and diabetes showed partial statistical difference between the two groups. Specific periodontopathic bacterial infection may affect HT in male cardiovascular patients.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00380-017-1042-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5914047", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1095887", 
        "issn": [
          "0910-8327", 
          "1615-2573"
        ], 
        "name": "Heart and Vessels", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "33"
      }
    ], 
    "name": "Specific periodontopathic bacterial infection affects hypertension in male cardiovascular disease patients", 
    "pagination": "198-204", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0c99e8ebf7421cf22f1fda160a4951408642671940c074c875e8a1ef0b5945f2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28803419"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8511258"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00380-017-1042-z"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1091197582"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00380-017-1042-z", 
      "https://app.dimensions.ai/details/publication/pub.1091197582"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89822_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00380-017-1042-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00380-017-1042-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00380-017-1042-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00380-017-1042-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00380-017-1042-z'


 

This table displays all metadata directly associated to this object as RDF triples.

285 TRIPLES      21 PREDICATES      73 URIs      37 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00380-017-1042-z schema:about N03ff1c7dc9cd4ff7971aef1889aec1eb
2 N269d659691a24c458bc3921a231005d8
3 N27b936d5ee334b22bbc1e571856845cd
4 N4d12b37791df40a6a8bccd33c6cd53e3
5 N552f761f955747148b2610d49223912d
6 N745671106f2d4b94a79a330a1d6ca07e
7 N770f863e00f5430dbf2954609d02a152
8 N8791e9f12fef4e79819a177a19d24b51
9 N99ca92bd21884608952c408cd4bd2f6f
10 Nb13a9694a95c40bea649946b4ca7120b
11 Nd019ef3967f24c7a9127f59ceaf292b9
12 Nd1e5c4c613fc4d76aa5e4d3ec7279899
13 Ndddd9196376547259371a25158e22619
14 Ne0a37133a58446748c437c6ad055c6d2
15 Ne2eef81e1cb6442da386d7218fae201a
16 Nf6c82da06473433e8e3a75c8ef67e542
17 anzsrc-for:11
18 anzsrc-for:1103
19 schema:author N7f2781f20fa0447ea38b3842cc222ae6
20 schema:citation sg:pub.10.1007/s11606-008-0787-6
21 https://doi.org/10.1001/jama.284.11.1406
22 https://doi.org/10.1016/j.ahj.2007.06.037
23 https://doi.org/10.1016/j.ahj.2016.07.018
24 https://doi.org/10.1016/j.atherosclerosis.2011.04.030
25 https://doi.org/10.1016/j.ejvs.2007.08.016
26 https://doi.org/10.1016/j.ijcard.2008.05.057
27 https://doi.org/10.1016/s0002-8703(99)70312-1
28 https://doi.org/10.1016/s0140-6736(05)67728-8
29 https://doi.org/10.1016/s0928-8244(03)00224-4
30 https://doi.org/10.1046/j..2003.com122.x
31 https://doi.org/10.1056/nejm199511233332106
32 https://doi.org/10.1056/nejmoa063186
33 https://doi.org/10.1089/met.2016.0018
34 https://doi.org/10.1093/eurheartj/suq001
35 https://doi.org/10.1097/md.0000000000002067
36 https://doi.org/10.1111/j.1600-0757.2006.00178.x
37 https://doi.org/10.1111/j.1743-6109.2008.01141.x
38 https://doi.org/10.1136/bmj.306.6879.688
39 https://doi.org/10.1136/postgradmedj-2016-134279
40 https://doi.org/10.1161/cir.0b013e31825719f3
41 https://doi.org/10.1161/cir.0b013e31828124ad
42 https://doi.org/10.1177/0022034515602693
43 https://doi.org/10.12659/msm.882050
44 https://doi.org/10.1371/journal.pone.0095521
45 https://doi.org/10.1536/ihj.53.209
46 https://doi.org/10.1902/annals.2001.6.1.9
47 https://doi.org/10.2174/1573403x10666140416094901
48 schema:datePublished 2018-02
49 schema:datePublishedReg 2018-02-01
50 schema:description Hypertension (HT) is a systemic disorder that results in the decline of quality of life and death. While patients with periodontitis are at a high risk of HT, little causal information has been provided to date. To clarify the relationship, periodontopathic bacterial infection in cardiovascular patients with or without HT was evaluated. The subjects were patients with (n = 412) or without (n = 199) HT who attended Tokyo Medical and Dental University hospital. Blood examinations and periodontal measurements were performed. Three periodontopathic bacteria existence and antibody titers were evaluated. We found that specific periodontopathic bacteria, Aggregatibacter actinomycetemcomitans and Prevotella intermedia, were highly detected in male subjects with HT compared to non-HT subjects, while they were comparable in the female patients. Mean probing pocket depth of elderly male patients with HT was higher compared to non-HT patients. The rates of obesity, dyslipidemia, and diabetes showed partial statistical difference between the two groups. Specific periodontopathic bacterial infection may affect HT in male cardiovascular patients.
51 schema:genre research_article
52 schema:inLanguage en
53 schema:isAccessibleForFree false
54 schema:isPartOf N4e2e4e0d1c5e4fe194f78a2377e721ef
55 N8c08b910f2354fe494b0771aa4e57152
56 sg:journal.1095887
57 schema:name Specific periodontopathic bacterial infection affects hypertension in male cardiovascular disease patients
58 schema:pagination 198-204
59 schema:productId N3904b5e25eb4467b8cf5cf867d64e514
60 N44d29f0dfa8d48a89f739de402e470a7
61 Na6b4aa4fbccf40e6a0f6b4df0cb5f466
62 Nec49b22abf69409482e4bc116df10076
63 Nedd97f711de44aa4a4a757863c31da78
64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091197582
65 https://doi.org/10.1007/s00380-017-1042-z
66 schema:sdDatePublished 2019-04-11T10:02
67 schema:sdLicense https://scigraph.springernature.com/explorer/license/
68 schema:sdPublisher N6d6e5ab6a12d4e2f9b6bca16b4787bf4
69 schema:url https://link.springer.com/10.1007%2Fs00380-017-1042-z
70 sgo:license sg:explorer/license/
71 sgo:sdDataset articles
72 rdf:type schema:ScholarlyArticle
73 N03ff1c7dc9cd4ff7971aef1889aec1eb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name DNA, Bacterial
75 rdf:type schema:DefinedTerm
76 N161eef04fd0a40cf900d5724386e4c70 rdf:first sg:person.0772072503.18
77 rdf:rest N2cbf321770ff4133bba7d691e1e51db0
78 N269d659691a24c458bc3921a231005d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Aged
80 rdf:type schema:DefinedTerm
81 N27b936d5ee334b22bbc1e571856845cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Aged, 80 and over
83 rdf:type schema:DefinedTerm
84 N2cbf321770ff4133bba7d691e1e51db0 rdf:first sg:person.0736053075.51
85 rdf:rest N392959b7962246b19f60fc5224c49b31
86 N3904b5e25eb4467b8cf5cf867d64e514 schema:name readcube_id
87 schema:value 0c99e8ebf7421cf22f1fda160a4951408642671940c074c875e8a1ef0b5945f2
88 rdf:type schema:PropertyValue
89 N392959b7962246b19f60fc5224c49b31 rdf:first sg:person.012757402652.04
90 rdf:rest N5e6a493a0b054151b4a3273a2c12a118
91 N44d29f0dfa8d48a89f739de402e470a7 schema:name nlm_unique_id
92 schema:value 8511258
93 rdf:type schema:PropertyValue
94 N4d12b37791df40a6a8bccd33c6cd53e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Humans
96 rdf:type schema:DefinedTerm
97 N4e2e4e0d1c5e4fe194f78a2377e721ef schema:volumeNumber 33
98 rdf:type schema:PublicationVolume
99 N552f761f955747148b2610d49223912d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Hypertension
101 rdf:type schema:DefinedTerm
102 N5d41860c8f6f423088255f1b8fc9ebb4 rdf:first sg:person.01266743300.99
103 rdf:rest rdf:nil
104 N5e6a493a0b054151b4a3273a2c12a118 rdf:first sg:person.01150350762.93
105 rdf:rest Nd974f4b25db04652ab274fe80c00437b
106 N6d6e5ab6a12d4e2f9b6bca16b4787bf4 schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 N745671106f2d4b94a79a330a1d6ca07e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Periodontitis
110 rdf:type schema:DefinedTerm
111 N770f863e00f5430dbf2954609d02a152 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Bacterial Infections
113 rdf:type schema:DefinedTerm
114 N7f2781f20fa0447ea38b3842cc222ae6 rdf:first sg:person.01320016400.47
115 rdf:rest N161eef04fd0a40cf900d5724386e4c70
116 N8791e9f12fef4e79819a177a19d24b51 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Survival Rate
118 rdf:type schema:DefinedTerm
119 N8b22038fbb6b4c5cbb69389537a2edfd rdf:first sg:person.0656160415.25
120 rdf:rest N5d41860c8f6f423088255f1b8fc9ebb4
121 N8c08b910f2354fe494b0771aa4e57152 schema:issueNumber 2
122 rdf:type schema:PublicationIssue
123 N99ca92bd21884608952c408cd4bd2f6f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Middle Aged
125 rdf:type schema:DefinedTerm
126 Na6b4aa4fbccf40e6a0f6b4df0cb5f466 schema:name pubmed_id
127 schema:value 28803419
128 rdf:type schema:PropertyValue
129 Nb13a9694a95c40bea649946b4ca7120b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Female
131 rdf:type schema:DefinedTerm
132 Nc3571a2297d74552a2235d1ebe4c0146 rdf:first sg:person.01344051345.30
133 rdf:rest N8b22038fbb6b4c5cbb69389537a2edfd
134 Nd019ef3967f24c7a9127f59ceaf292b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Quality of Life
136 rdf:type schema:DefinedTerm
137 Nd1e5c4c613fc4d76aa5e4d3ec7279899 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Cause of Death
139 rdf:type schema:DefinedTerm
140 Nd974f4b25db04652ab274fe80c00437b rdf:first sg:person.01012024207.33
141 rdf:rest Nc3571a2297d74552a2235d1ebe4c0146
142 Ndddd9196376547259371a25158e22619 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Bacteria
144 rdf:type schema:DefinedTerm
145 Ne0a37133a58446748c437c6ad055c6d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Male
147 rdf:type schema:DefinedTerm
148 Ne2eef81e1cb6442da386d7218fae201a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Retrospective Studies
150 rdf:type schema:DefinedTerm
151 Nec49b22abf69409482e4bc116df10076 schema:name doi
152 schema:value 10.1007/s00380-017-1042-z
153 rdf:type schema:PropertyValue
154 Nedd97f711de44aa4a4a757863c31da78 schema:name dimensions_id
155 schema:value pub.1091197582
156 rdf:type schema:PropertyValue
157 Nf6c82da06473433e8e3a75c8ef67e542 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Japan
159 rdf:type schema:DefinedTerm
160 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
161 schema:name Medical and Health Sciences
162 rdf:type schema:DefinedTerm
163 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
164 schema:name Clinical Sciences
165 rdf:type schema:DefinedTerm
166 sg:grant.5914047 http://pending.schema.org/fundedItem sg:pub.10.1007/s00380-017-1042-z
167 rdf:type schema:MonetaryGrant
168 sg:journal.1095887 schema:issn 0910-8327
169 1615-2573
170 schema:name Heart and Vessels
171 rdf:type schema:Periodical
172 sg:person.01012024207.33 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
173 schema:familyName Komuro
174 schema:givenName Issei
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012024207.33
176 rdf:type schema:Person
177 sg:person.01150350762.93 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
178 schema:familyName Akazawa
179 schema:givenName Hiroshi
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150350762.93
181 rdf:type schema:Person
182 sg:person.01266743300.99 schema:affiliation https://www.grid.ac/institutes/grid.265073.5
183 schema:familyName Isobe
184 schema:givenName Mitsuaki
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266743300.99
186 rdf:type schema:Person
187 sg:person.012757402652.04 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
188 schema:familyName Ikeda
189 schema:givenName Yuichi
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012757402652.04
191 rdf:type schema:Person
192 sg:person.01320016400.47 schema:affiliation https://www.grid.ac/institutes/grid.462431.6
193 schema:familyName Aoyama
194 schema:givenName Norio
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320016400.47
196 rdf:type schema:Person
197 sg:person.01344051345.30 schema:affiliation https://www.grid.ac/institutes/grid.462431.6
198 schema:familyName Minabe
199 schema:givenName Masato
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344051345.30
201 rdf:type schema:Person
202 sg:person.0656160415.25 schema:affiliation https://www.grid.ac/institutes/grid.265073.5
203 schema:familyName Izumi
204 schema:givenName Yuichi
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656160415.25
206 rdf:type schema:Person
207 sg:person.0736053075.51 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
208 schema:familyName Kumagai
209 schema:givenName Hidetoshi
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736053075.51
211 rdf:type schema:Person
212 sg:person.0772072503.18 schema:affiliation https://www.grid.ac/institutes/grid.265073.5
213 schema:familyName Suzuki
214 schema:givenName Jun-ichi
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772072503.18
216 rdf:type schema:Person
217 sg:pub.10.1007/s11606-008-0787-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009231770
218 https://doi.org/10.1007/s11606-008-0787-6
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1001/jama.284.11.1406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052920186
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/j.ahj.2007.06.037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053497239
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1016/j.ahj.2016.07.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014583077
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/j.atherosclerosis.2011.04.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003892934
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/j.ejvs.2007.08.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001756836
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1016/j.ijcard.2008.05.057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004611762
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1016/s0002-8703(99)70312-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035902375
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1016/s0140-6736(05)67728-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009590961
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/s0928-8244(03)00224-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036815923
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1046/j..2003.com122.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020776384
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1056/nejm199511233332106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051075780
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1056/nejmoa063186 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029455137
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1089/met.2016.0018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059299044
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1093/eurheartj/suq001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011099933
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1097/md.0000000000002067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051878439
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1111/j.1600-0757.2006.00178.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026692366
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1111/j.1743-6109.2008.01141.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027716609
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1136/bmj.306.6879.688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006093807
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1136/postgradmedj-2016-134279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062821399
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1161/cir.0b013e31825719f3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010818306
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1161/cir.0b013e31828124ad schema:sameAs https://app.dimensions.ai/details/publication/pub.1052501077
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1177/0022034515602693 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007211019
263 rdf:type schema:CreativeWork
264 https://doi.org/10.12659/msm.882050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012138938
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1371/journal.pone.0095521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002757265
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1536/ihj.53.209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036075512
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1902/annals.2001.6.1.9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068728336
271 rdf:type schema:CreativeWork
272 https://doi.org/10.2174/1573403x10666140416094901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069208019
273 rdf:type schema:CreativeWork
274 https://www.grid.ac/institutes/grid.265073.5 schema:alternateName Tokyo Medical and Dental University
275 schema:name Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
276 Department of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8549, Tokyo, Japan
277 Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, 113-8549, Tokyo, Japan
278 rdf:type schema:Organization
279 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
280 schema:name Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
281 Department of Cardiovascular Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
282 rdf:type schema:Organization
283 https://www.grid.ac/institutes/grid.462431.6 schema:alternateName Kanagawa Dental University
284 schema:name Division of Periodontology, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaokacho, 238-8580, Yokosuka, Kanagawa, Japan
285 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...