Comparison of 8-frame and 16-frame thallium-201 gated myocardial perfusion SPECT for determining left ventricular systolic and diastolic parameters View Full Text


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Article Info

DATE

2017-07

AUTHORS

Satoshi Kurisu, Yoji Sumimoto, Hiroki Ikenaga, Noriaki Watanabe, Ken Ishibashi, Yoshihiro Dohi, Yukihiro Fukuda, Yasuki Kihara

ABSTRACT

The myocardial perfusion single photon emission computed tomography synchronized with the electrocardiogram (gated SPECT) has been widely used for the assessment of left ventricular (LV) systolic and diastolic functions using Quantitative gated SPECT. The aim of this study was to compare the effects of 8-frame and 16-frame thallium-201 (Tl-201) gated SPECT for determining LV systolic and diastolic parameters. The study population included 42 patients with suspected coronary artery disease who underwent gated SPECT by clinical indication. LV systolic and diastolic parameters were assessed on 8-frame and 16-frame gated SPECT. There were good correlations in end-diastolic volume (r = 0.99, p < 0.001), end-systolic volume (ESV) (r = 0.97, p < 0.001) and ejection fraction (EF) (r = 0.95, p < 0.001) between 8-frame and 16-frame gated SPECT. Bland-Altman plot showed a significant negative slope of -0.08 in EDV indicating a larger difference for larger EDV. Eight-frame gated SPECT overestimated ESV by 2.3 ml, and underestimated EF by -4.2% than 16-frame gated SPECT. There were good correlations in peak filling rate (PFR) (r = 0.87, p < 0.001), one third mean filling rate (r = 0.87, p < 0.001) and time to PFR (r = 0.61, p < 0.001) between 8-frame and 16-frame gated SPECT. Eight-frame gated SPECT underestimated PFR by -0.22 than 16-frame gated SPECT. Eight-frame gated SPECT estimated as much MFR/3 and TPFR as 16-frame gated SPECT. According to the data, the study suggested that 8-frame Tl-201 gated SPECT could underestimate systolic and/or diastolic parameter when compared with 16-frame gated SPECT. More... »

PAGES

790-795

References to SciGraph publications

  • 2014-02. Influence of left ventricular geometry on thallium-201 gated single-photon emission tomographic findings in patients with known or suspected coronary artery disease in ANNALS OF NUCLEAR MEDICINE
  • 1999-05. Comparison of Tc-99m sestamibi and Tl-201 gated perfusion SPECT in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2015-01. Electrocardiographic J waves are associated with right ventricular morphology and function: evaluation by cardiac magnetic resonance imaging in HEART AND VESSELS
  • 2001-09. Assessment of left ventricular diastolic function with electrocardiography-gated myocardial perfusion SPECT: Comparison with multigated equilibrium radionuclide angiography in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2001-11. Evaluation of left ventricular endocardial volumes and ejection fractions computed from gated perfusion SPECT with magnetic resonance imaging: Comparison of two methods in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2016-08. Effects of liraglutide, a glucagon-like peptide-1 analog, on left ventricular remodeling assessed by cardiac magnetic resonance imaging in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention in HEART AND VESSELS
  • 2008-11. Is 16-frame really superior to 8-frame gated SPECT for the assessment of left ventricular volumes and ejection fraction? Comparison of two simultaneously acquired gated SPECT studies in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2003-10. Comparison of 16-frame and 8-frame gated SPET imaging for determination of left ventricular volumes and ejection fraction in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00380-016-0935-6

    DOI

    http://dx.doi.org/10.1007/s00380-016-0935-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1050483009

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27988844


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