Impairment of flow-mediated dilation correlates with aortic dilation in patients with Marfan syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-07

AUTHORS

Munenori Takata, Eisuke Amiya, Masafumi Watanabe, Kazuko Omori, Yasushi Imai, Daishi Fujita, Hiroshi Nishimura, Masayoshi Kato, Tetsuro Morota, Kan Nawata, Atsuko Ozeki, Aya Watanabe, Shuichi Kawarasaki, Yumiko Hosoya, Tomoko Nakao, Koji Maemura, Ryozo Nagai, Yasunobu Hirata, Issei Komuro

ABSTRACT

Marfan syndrome is an inherited disorder characterized by genetic abnormality of microfibrillar connective tissue proteins. Endothelial dysfunction is thought to cause aortic dilation in subjects with a bicuspid aortic valve; however, the role of endothelial dysfunction and endothelial damaging factors has not been elucidated in Marfan syndrome. Flow-mediated dilation, a noninvasive measurement of endothelial function, was evaluated in 39 patients with Marfan syndrome. Aortic diameter was measured at the aortic annulus, aortic root at the sinus of Valsalva, sinotubular junction and ascending aorta by echocardiography, and adjusted for body surface area (BSA). The mean value of flow-mediated dilation was 6.5 ± 2.4 %. Flow-mediated dilation had a negative correlation with the diameter of the ascending thoracic aorta (AscAd)/BSA (R = -0.39, p = 0.020) and multivariate analysis revealed that flow-mediated dilation was an independent factor predicting AscAd/BSA, whereas other segments of the aorta had no association. Furthermore, Brinkman index had a somewhat greater influence on flow-mediated dilation (R = -0.42, p = 0.008). Although subjects who smoked tended to have a larger AscAd compared with non-smokers (AscA/BSA: 17.3 ± 1.8 versus 15.2 ± 3.0 mm/m(2), p = 0.013), there was no significant change in flow-mediated dilation, suggesting that smoking might affect aortic dilation via an independent pathway. Common atherogenic risks, such as impairment of flow-mediated dilation and smoking status, affected aortic dilation in subjects with Marfan syndrome. More... »

PAGES

478-485

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-013-0393-3

DOI

http://dx.doi.org/10.1007/s00380-013-0393-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045926909

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23852405


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aorta", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aortic Aneurysm", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endothelium, Vascular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Marfan Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multivariate Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Regional Blood Flow", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Smoking", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stress, Mechanical", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ultrasonography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vasodilation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takata", 
        "givenName": "Munenori", 
        "id": "sg:person.0634656307.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634656307.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amiya", 
        "givenName": "Eisuke", 
        "id": "sg:person.01027736463.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027736463.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Watanabe", 
        "givenName": "Masafumi", 
        "id": "sg:person.0704502634.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704502634.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Teikyo University", 
          "id": "https://www.grid.ac/institutes/grid.264706.1", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
            "Department of Laboratory Medicine, Teikyo University School of Medical Technology, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Omori", 
        "givenName": "Kazuko", 
        "id": "sg:person.01365346106.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365346106.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imai", 
        "givenName": "Yasushi", 
        "id": "sg:person.012503520402.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012503520402.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fujita", 
        "givenName": "Daishi", 
        "id": "sg:person.01150107730.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150107730.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishimura", 
        "givenName": "Hiroshi", 
        "id": "sg:person.0613772622.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613772622.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kato", 
        "givenName": "Masayoshi", 
        "id": "sg:person.014370225532.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014370225532.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morota", 
        "givenName": "Tetsuro", 
        "id": "sg:person.01113260233.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113260233.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nawata", 
        "givenName": "Kan", 
        "id": "sg:person.01167447253.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167447253.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ozeki", 
        "givenName": "Atsuko", 
        "id": "sg:person.01117262711.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117262711.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Watanabe", 
        "givenName": "Aya", 
        "id": "sg:person.01260413463.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260413463.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kawarasaki", 
        "givenName": "Shuichi", 
        "id": "sg:person.01326526663.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326526663.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hosoya", 
        "givenName": "Yumiko", 
        "id": "sg:person.01251406234.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251406234.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakao", 
        "givenName": "Tomoko", 
        "id": "sg:person.0603122563.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603122563.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University", 
          "id": "https://www.grid.ac/institutes/grid.174567.6", 
          "name": [
            "Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maemura", 
        "givenName": "Koji", 
        "id": "sg:person.01314320222.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314320222.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Jichi Medical University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415016.7", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan", 
            "Jichi Medical School, Tochigi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagai", 
        "givenName": "Ryozo", 
        "id": "sg:person.0772176333.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772176333.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirata", 
        "givenName": "Yasunobu", 
        "id": "sg:person.07703025442.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07703025442.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Komuro", 
        "givenName": "Issei", 
        "id": "sg:person.01012024207.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012024207.33"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00380-011-0225-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000794890", 
          "https://doi.org/10.1007/s00380-011-0225-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s100169900113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005964990", 
          "https://doi.org/10.1007/s100169900113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0828-282x(10)70370-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008278191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.99.7.909", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008428908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/physrev.00047.2009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008943594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.jvca.2010.11.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010954877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0741-5214(99)70049-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0741-5214(99)70049-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.99.20.2677", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013750654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.athoracsur.2006.01.070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013980673"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(10)80218-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017397984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.101.20.2345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019194109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.110.012187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021992484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.01238.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023363968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.01238.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023363968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2012/165957", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024379810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10623329309102697", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030457635"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2009.08.080", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030775391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(01)01746-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031448054"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2007.05.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032417968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199505043321804", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033876340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm.2711", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035131108", 
          "https://doi.org/10.1038/nm.2711"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-8703(00)90045-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037995562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.0000199268.27395.4f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043755326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.0000199268.27395.4f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043755326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.athoracsur.2006.11.086", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045229898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(03)00922-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046801150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(03)00922-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046801150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/hrt.75.4.389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051910472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)67789-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051956451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/cs20100476", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052344586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/cs20100476", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052344586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-8628(19960424)62:4<417::aid-ajmg15>3.0.co;2-r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053284167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.00868.2010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053500640"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00380-011-0161-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053518645", 
          "https://doi.org/10.1007/s00380-011-0161-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ehj.2004.04.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054732521"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-07", 
    "datePublishedReg": "2014-07-01", 
    "description": "Marfan syndrome is an inherited disorder characterized by genetic abnormality of microfibrillar connective tissue proteins. Endothelial dysfunction is thought to cause aortic dilation in subjects with a bicuspid aortic valve; however, the role of endothelial dysfunction and endothelial damaging factors has not been elucidated in Marfan syndrome. Flow-mediated dilation, a noninvasive measurement of endothelial function, was evaluated in 39 patients with Marfan syndrome. Aortic diameter was measured at the aortic annulus, aortic root at the sinus of Valsalva, sinotubular junction and ascending aorta by echocardiography, and adjusted for body surface area (BSA). The mean value of flow-mediated dilation was 6.5 \u00b1 2.4 %. Flow-mediated dilation had a negative correlation with the diameter of the ascending thoracic aorta (AscAd)/BSA (R = -0.39, p = 0.020) and multivariate analysis revealed that flow-mediated dilation was an independent factor predicting AscAd/BSA, whereas other segments of the aorta had no association. Furthermore, Brinkman index had a somewhat greater influence on flow-mediated dilation (R = -0.42, p = 0.008). Although subjects who smoked tended to have a larger AscAd compared with non-smokers (AscA/BSA: 17.3 \u00b1 1.8 versus 15.2 \u00b1 3.0 mm/m(2), p = 0.013), there was no significant change in flow-mediated dilation, suggesting that smoking might affect aortic dilation via an independent pathway. Common atherogenic risks, such as impairment of flow-mediated dilation and smoking status, affected aortic dilation in subjects with Marfan syndrome.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00380-013-0393-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6125934", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6078132", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6034334", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6116868", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1095887", 
        "issn": [
          "0910-8327", 
          "1615-2573"
        ], 
        "name": "Heart and Vessels", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "29"
      }
    ], 
    "name": "Impairment of flow-mediated dilation correlates with aortic dilation in patients with Marfan syndrome", 
    "pagination": "478-485", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "dac554849a79aa1b54ce6d11919d9ffba60d38184295bfdecf72f595b26a465e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23852405"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8511258"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00380-013-0393-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1045926909"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00380-013-0393-3", 
      "https://app.dimensions.ai/details/publication/pub.1045926909"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T23:25", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000515.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00380-013-0393-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00380-013-0393-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00380-013-0393-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00380-013-0393-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00380-013-0393-3'


 

This table displays all metadata directly associated to this object as RDF triples.

380 TRIPLES      21 PREDICATES      77 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00380-013-0393-3 schema:about N0585abea5a50404eb067b418f642c1d3
2 N0ac32bae382d46f5a9ff6cf8e841d82b
3 N109e287935c24751adc330fdd36c2e12
4 N2801fc96b7874a4898ca95b4bb7190ba
5 N34e8a38641ef4f5fb68c9ee598f7861c
6 N3587dc34f585490aa9c34012edffafcd
7 N3a6869ef0fc9468ca4a791b92086323f
8 N53d296f2055a497d8e8da3da17f5ebba
9 N58735c5637264313b053a3bd0056248a
10 N59cfaba8f8174321b7665d2713cb9c48
11 N68bd7fe13efd4fc9a616de3cbf8dccca
12 N7bbebb43a82c4c8398689e0880187b73
13 N883773a6041b4b819dc3f4f0340d833a
14 Na76ca31b407e4fbaa9dce37c789668c8
15 Nad80fd89d7874377a999e7bc9b2107e8
16 Nf7cc0033d3034998924f71e39bab872a
17 Nfbc3a8b1a28c47e38ade1ad63636af51
18 anzsrc-for:11
19 anzsrc-for:1102
20 schema:author Nc3347f2e3c244731ae2afafe24765e4b
21 schema:citation sg:pub.10.1007/s00380-011-0161-1
22 sg:pub.10.1007/s00380-011-0225-2
23 sg:pub.10.1007/s100169900113
24 sg:pub.10.1038/nm.2711
25 https://doi.org/10.1002/(sici)1096-8628(19960424)62:4<417::aid-ajmg15>3.0.co;2-r
26 https://doi.org/10.1016/j.athoracsur.2006.01.070
27 https://doi.org/10.1016/j.athoracsur.2006.11.086
28 https://doi.org/10.1016/j.ehj.2004.04.033
29 https://doi.org/10.1016/j.ijcard.2007.05.008
30 https://doi.org/10.1016/j.jacc.2009.08.080
31 https://doi.org/10.1016/s0002-8703(00)90045-0
32 https://doi.org/10.1016/s0140-6736(05)67789-6
33 https://doi.org/10.1016/s0735-1097(01)01746-6
34 https://doi.org/10.1016/s0735-1097(03)00922-7
35 https://doi.org/10.1016/s0735-1097(10)80218-9
36 https://doi.org/10.1016/s0741-5214(99)70049-2
37 https://doi.org/10.1016/s0828-282x(10)70370-6
38 https://doi.org/10.1042/cs20100476
39 https://doi.org/10.1053/j.jvca.2010.11.019
40 https://doi.org/10.1056/nejm199505043321804
41 https://doi.org/10.1136/hrt.75.4.389
42 https://doi.org/10.1152/ajpheart.00868.2010
43 https://doi.org/10.1152/ajpheart.01238.2004
44 https://doi.org/10.1152/physrev.00047.2009
45 https://doi.org/10.1155/2012/165957
46 https://doi.org/10.1161/01.atv.0000199268.27395.4f
47 https://doi.org/10.1161/01.cir.101.20.2345
48 https://doi.org/10.1161/01.cir.99.20.2677
49 https://doi.org/10.1161/01.cir.99.7.909
50 https://doi.org/10.1161/circulationaha.110.012187
51 https://doi.org/10.3109/10623329309102697
52 schema:datePublished 2014-07
53 schema:datePublishedReg 2014-07-01
54 schema:description Marfan syndrome is an inherited disorder characterized by genetic abnormality of microfibrillar connective tissue proteins. Endothelial dysfunction is thought to cause aortic dilation in subjects with a bicuspid aortic valve; however, the role of endothelial dysfunction and endothelial damaging factors has not been elucidated in Marfan syndrome. Flow-mediated dilation, a noninvasive measurement of endothelial function, was evaluated in 39 patients with Marfan syndrome. Aortic diameter was measured at the aortic annulus, aortic root at the sinus of Valsalva, sinotubular junction and ascending aorta by echocardiography, and adjusted for body surface area (BSA). The mean value of flow-mediated dilation was 6.5 ± 2.4 %. Flow-mediated dilation had a negative correlation with the diameter of the ascending thoracic aorta (AscAd)/BSA (R = -0.39, p = 0.020) and multivariate analysis revealed that flow-mediated dilation was an independent factor predicting AscAd/BSA, whereas other segments of the aorta had no association. Furthermore, Brinkman index had a somewhat greater influence on flow-mediated dilation (R = -0.42, p = 0.008). Although subjects who smoked tended to have a larger AscAd compared with non-smokers (AscA/BSA: 17.3 ± 1.8 versus 15.2 ± 3.0 mm/m(2), p = 0.013), there was no significant change in flow-mediated dilation, suggesting that smoking might affect aortic dilation via an independent pathway. Common atherogenic risks, such as impairment of flow-mediated dilation and smoking status, affected aortic dilation in subjects with Marfan syndrome.
55 schema:genre research_article
56 schema:inLanguage en
57 schema:isAccessibleForFree false
58 schema:isPartOf N5b127a9989ef477eb5c3167ee1c94da6
59 Ne635fce2409442bf9c6459c6a9a9afbf
60 sg:journal.1095887
61 schema:name Impairment of flow-mediated dilation correlates with aortic dilation in patients with Marfan syndrome
62 schema:pagination 478-485
63 schema:productId N22f848687bbc4b8f8dbbb3ab1af774ca
64 N3f9386762ed94838a582ccf8ff8c673e
65 N444a7eb667d64ae1a0d7a97f80008462
66 N9315923499cf4eb9aae31d43d33d0ae6
67 Nfdaf2da8675b4fad96ccc18941d29a5f
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045926909
69 https://doi.org/10.1007/s00380-013-0393-3
70 schema:sdDatePublished 2019-04-10T23:25
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher Na30020d7c20f4660b77a582280208c8f
73 schema:url http://link.springer.com/10.1007%2Fs00380-013-0393-3
74 sgo:license sg:explorer/license/
75 sgo:sdDataset articles
76 rdf:type schema:ScholarlyArticle
77 N00e52c0e90354698809d0dff24f0ba87 rdf:first sg:person.01167447253.69
78 rdf:rest Nf86a815ac8e24727815abcd56733a4ad
79 N0585abea5a50404eb067b418f642c1d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Marfan Syndrome
81 rdf:type schema:DefinedTerm
82 N0ac32bae382d46f5a9ff6cf8e841d82b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Vasodilation
84 rdf:type schema:DefinedTerm
85 N109e287935c24751adc330fdd36c2e12 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Risk Factors
87 rdf:type schema:DefinedTerm
88 N1ecb4d47d5c54272b4c6e31a75283b24 rdf:first sg:person.012503520402.17
89 rdf:rest N3337a99406d142888b960c99005af06d
90 N22f848687bbc4b8f8dbbb3ab1af774ca schema:name readcube_id
91 schema:value dac554849a79aa1b54ce6d11919d9ffba60d38184295bfdecf72f595b26a465e
92 rdf:type schema:PropertyValue
93 N2801fc96b7874a4898ca95b4bb7190ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Aortic Aneurysm
95 rdf:type schema:DefinedTerm
96 N3337a99406d142888b960c99005af06d rdf:first sg:person.01150107730.46
97 rdf:rest Nf8a7fbcb931b44ffbd92e0eab71e48b1
98 N34e8a38641ef4f5fb68c9ee598f7861c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Smoking
100 rdf:type schema:DefinedTerm
101 N3587dc34f585490aa9c34012edffafcd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Adult
103 rdf:type schema:DefinedTerm
104 N369917156e0a4f1b959303a058a758cb rdf:first sg:person.0603122563.31
105 rdf:rest N77b358da3be54207ac3d68fa9653aca4
106 N3a6869ef0fc9468ca4a791b92086323f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Young Adult
108 rdf:type schema:DefinedTerm
109 N3f9386762ed94838a582ccf8ff8c673e schema:name dimensions_id
110 schema:value pub.1045926909
111 rdf:type schema:PropertyValue
112 N3f966a1bc6fe428e9179dc343fba88cc rdf:first sg:person.0772176333.38
113 rdf:rest Neec86c2f73fa4539a2f201758ec8d8a8
114 N444a7eb667d64ae1a0d7a97f80008462 schema:name pubmed_id
115 schema:value 23852405
116 rdf:type schema:PropertyValue
117 N480ae05c71894733afdc810c053e8d48 rdf:first sg:person.01365346106.71
118 rdf:rest N1ecb4d47d5c54272b4c6e31a75283b24
119 N52d44c49b8c44330b37ddd34f8c56503 rdf:first sg:person.01027736463.70
120 rdf:rest N67d749f8d9d74aa38dfa9eeaca5348a5
121 N53d296f2055a497d8e8da3da17f5ebba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Stress, Mechanical
123 rdf:type schema:DefinedTerm
124 N5421a51ab0894591aa69a5445ac9701a rdf:first sg:person.014370225532.45
125 rdf:rest N67787d2d3ddd4312b22b54c98cf80689
126 N58735c5637264313b053a3bd0056248a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Aorta
128 rdf:type schema:DefinedTerm
129 N59cfaba8f8174321b7665d2713cb9c48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Multivariate Analysis
131 rdf:type schema:DefinedTerm
132 N5b127a9989ef477eb5c3167ee1c94da6 schema:issueNumber 4
133 rdf:type schema:PublicationIssue
134 N67787d2d3ddd4312b22b54c98cf80689 rdf:first sg:person.01113260233.38
135 rdf:rest N00e52c0e90354698809d0dff24f0ba87
136 N67d749f8d9d74aa38dfa9eeaca5348a5 rdf:first sg:person.0704502634.67
137 rdf:rest N480ae05c71894733afdc810c053e8d48
138 N68bd7fe13efd4fc9a616de3cbf8dccca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Humans
140 rdf:type schema:DefinedTerm
141 N69699e4490ef4eb48b6bfc923709c779 rdf:first sg:person.01012024207.33
142 rdf:rest rdf:nil
143 N77b358da3be54207ac3d68fa9653aca4 rdf:first sg:person.01314320222.11
144 rdf:rest N3f966a1bc6fe428e9179dc343fba88cc
145 N7bbebb43a82c4c8398689e0880187b73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Male
147 rdf:type schema:DefinedTerm
148 N7bee8f3d110748efa29c0fe6a10e1e80 rdf:first sg:person.01251406234.40
149 rdf:rest N369917156e0a4f1b959303a058a758cb
150 N80da9ec1f41442998dd827cc07769f01 rdf:first sg:person.01260413463.46
151 rdf:rest N886271eccfc6416f9115a638b3c351b7
152 N883773a6041b4b819dc3f4f0340d833a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Female
154 rdf:type schema:DefinedTerm
155 N886271eccfc6416f9115a638b3c351b7 rdf:first sg:person.01326526663.31
156 rdf:rest N7bee8f3d110748efa29c0fe6a10e1e80
157 N9315923499cf4eb9aae31d43d33d0ae6 schema:name nlm_unique_id
158 schema:value 8511258
159 rdf:type schema:PropertyValue
160 Na30020d7c20f4660b77a582280208c8f schema:name Springer Nature - SN SciGraph project
161 rdf:type schema:Organization
162 Na76ca31b407e4fbaa9dce37c789668c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Ultrasonography
164 rdf:type schema:DefinedTerm
165 Nad80fd89d7874377a999e7bc9b2107e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Regional Blood Flow
167 rdf:type schema:DefinedTerm
168 Nc3347f2e3c244731ae2afafe24765e4b rdf:first sg:person.0634656307.35
169 rdf:rest N52d44c49b8c44330b37ddd34f8c56503
170 Ne635fce2409442bf9c6459c6a9a9afbf schema:volumeNumber 29
171 rdf:type schema:PublicationVolume
172 Neec86c2f73fa4539a2f201758ec8d8a8 rdf:first sg:person.07703025442.98
173 rdf:rest N69699e4490ef4eb48b6bfc923709c779
174 Nf7cc0033d3034998924f71e39bab872a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Endothelium, Vascular
176 rdf:type schema:DefinedTerm
177 Nf86a815ac8e24727815abcd56733a4ad rdf:first sg:person.01117262711.70
178 rdf:rest N80da9ec1f41442998dd827cc07769f01
179 Nf8a7fbcb931b44ffbd92e0eab71e48b1 rdf:first sg:person.0613772622.35
180 rdf:rest N5421a51ab0894591aa69a5445ac9701a
181 Nfbc3a8b1a28c47e38ade1ad63636af51 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Middle Aged
183 rdf:type schema:DefinedTerm
184 Nfdaf2da8675b4fad96ccc18941d29a5f schema:name doi
185 schema:value 10.1007/s00380-013-0393-3
186 rdf:type schema:PropertyValue
187 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
188 schema:name Medical and Health Sciences
189 rdf:type schema:DefinedTerm
190 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
191 schema:name Cardiorespiratory Medicine and Haematology
192 rdf:type schema:DefinedTerm
193 sg:grant.6034334 http://pending.schema.org/fundedItem sg:pub.10.1007/s00380-013-0393-3
194 rdf:type schema:MonetaryGrant
195 sg:grant.6078132 http://pending.schema.org/fundedItem sg:pub.10.1007/s00380-013-0393-3
196 rdf:type schema:MonetaryGrant
197 sg:grant.6116868 http://pending.schema.org/fundedItem sg:pub.10.1007/s00380-013-0393-3
198 rdf:type schema:MonetaryGrant
199 sg:grant.6125934 http://pending.schema.org/fundedItem sg:pub.10.1007/s00380-013-0393-3
200 rdf:type schema:MonetaryGrant
201 sg:journal.1095887 schema:issn 0910-8327
202 1615-2573
203 schema:name Heart and Vessels
204 rdf:type schema:Periodical
205 sg:person.01012024207.33 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
206 schema:familyName Komuro
207 schema:givenName Issei
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012024207.33
209 rdf:type schema:Person
210 sg:person.01027736463.70 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
211 schema:familyName Amiya
212 schema:givenName Eisuke
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027736463.70
214 rdf:type schema:Person
215 sg:person.01113260233.38 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
216 schema:familyName Morota
217 schema:givenName Tetsuro
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113260233.38
219 rdf:type schema:Person
220 sg:person.01117262711.70 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
221 schema:familyName Ozeki
222 schema:givenName Atsuko
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117262711.70
224 rdf:type schema:Person
225 sg:person.01150107730.46 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
226 schema:familyName Fujita
227 schema:givenName Daishi
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150107730.46
229 rdf:type schema:Person
230 sg:person.01167447253.69 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
231 schema:familyName Nawata
232 schema:givenName Kan
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167447253.69
234 rdf:type schema:Person
235 sg:person.012503520402.17 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
236 schema:familyName Imai
237 schema:givenName Yasushi
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012503520402.17
239 rdf:type schema:Person
240 sg:person.01251406234.40 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
241 schema:familyName Hosoya
242 schema:givenName Yumiko
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251406234.40
244 rdf:type schema:Person
245 sg:person.01260413463.46 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
246 schema:familyName Watanabe
247 schema:givenName Aya
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260413463.46
249 rdf:type schema:Person
250 sg:person.01314320222.11 schema:affiliation https://www.grid.ac/institutes/grid.174567.6
251 schema:familyName Maemura
252 schema:givenName Koji
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314320222.11
254 rdf:type schema:Person
255 sg:person.01326526663.31 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
256 schema:familyName Kawarasaki
257 schema:givenName Shuichi
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326526663.31
259 rdf:type schema:Person
260 sg:person.01365346106.71 schema:affiliation https://www.grid.ac/institutes/grid.264706.1
261 schema:familyName Omori
262 schema:givenName Kazuko
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365346106.71
264 rdf:type schema:Person
265 sg:person.014370225532.45 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
266 schema:familyName Kato
267 schema:givenName Masayoshi
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014370225532.45
269 rdf:type schema:Person
270 sg:person.0603122563.31 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
271 schema:familyName Nakao
272 schema:givenName Tomoko
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603122563.31
274 rdf:type schema:Person
275 sg:person.0613772622.35 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
276 schema:familyName Nishimura
277 schema:givenName Hiroshi
278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613772622.35
279 rdf:type schema:Person
280 sg:person.0634656307.35 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
281 schema:familyName Takata
282 schema:givenName Munenori
283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634656307.35
284 rdf:type schema:Person
285 sg:person.0704502634.67 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
286 schema:familyName Watanabe
287 schema:givenName Masafumi
288 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704502634.67
289 rdf:type schema:Person
290 sg:person.07703025442.98 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
291 schema:familyName Hirata
292 schema:givenName Yasunobu
293 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07703025442.98
294 rdf:type schema:Person
295 sg:person.0772176333.38 schema:affiliation https://www.grid.ac/institutes/grid.415016.7
296 schema:familyName Nagai
297 schema:givenName Ryozo
298 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772176333.38
299 rdf:type schema:Person
300 sg:pub.10.1007/s00380-011-0161-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053518645
301 https://doi.org/10.1007/s00380-011-0161-1
302 rdf:type schema:CreativeWork
303 sg:pub.10.1007/s00380-011-0225-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000794890
304 https://doi.org/10.1007/s00380-011-0225-2
305 rdf:type schema:CreativeWork
306 sg:pub.10.1007/s100169900113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005964990
307 https://doi.org/10.1007/s100169900113
308 rdf:type schema:CreativeWork
309 sg:pub.10.1038/nm.2711 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035131108
310 https://doi.org/10.1038/nm.2711
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1002/(sici)1096-8628(19960424)62:4<417::aid-ajmg15>3.0.co;2-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1053284167
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1016/j.athoracsur.2006.01.070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013980673
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1016/j.athoracsur.2006.11.086 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045229898
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1016/j.ehj.2004.04.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054732521
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1016/j.ijcard.2007.05.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032417968
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1016/j.jacc.2009.08.080 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030775391
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1016/s0002-8703(00)90045-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037995562
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1016/s0140-6736(05)67789-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051956451
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/s0735-1097(01)01746-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031448054
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1016/s0735-1097(03)00922-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046801150
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1016/s0735-1097(10)80218-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017397984
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1016/s0741-5214(99)70049-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012400854
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1016/s0828-282x(10)70370-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008278191
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1042/cs20100476 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052344586
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1053/j.jvca.2010.11.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010954877
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1056/nejm199505043321804 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033876340
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1136/hrt.75.4.389 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051910472
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1152/ajpheart.00868.2010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053500640
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1152/ajpheart.01238.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023363968
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1152/physrev.00047.2009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008943594
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1155/2012/165957 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024379810
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1161/01.atv.0000199268.27395.4f schema:sameAs https://app.dimensions.ai/details/publication/pub.1043755326
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1161/01.cir.101.20.2345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019194109
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1161/01.cir.99.20.2677 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013750654
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1161/01.cir.99.7.909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008428908
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1161/circulationaha.110.012187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021992484
363 rdf:type schema:CreativeWork
364 https://doi.org/10.3109/10623329309102697 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030457635
365 rdf:type schema:CreativeWork
366 https://www.grid.ac/institutes/grid.174567.6 schema:alternateName Nagasaki University
367 schema:name Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
368 rdf:type schema:Organization
369 https://www.grid.ac/institutes/grid.264706.1 schema:alternateName Teikyo University
370 schema:name Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
371 Department of Laboratory Medicine, Teikyo University School of Medical Technology, Tokyo, Japan
372 rdf:type schema:Organization
373 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
374 schema:name Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
375 Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
376 rdf:type schema:Organization
377 https://www.grid.ac/institutes/grid.415016.7 schema:alternateName Jichi Medical University Hospital
378 schema:name Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
379 Jichi Medical School, Tochigi, Japan
380 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...