Incidence of periprocedural myocardial infarction and cardiac biomarker testing after percutaneous coronary intervention in Japan: results from a multicenter registry View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-12-29

AUTHORS

Takahide Arai, Shinsuke Yuasa, Hiroaki Miyata, Akio Kawamura, Yuichiro Maekawa, Shiro Ishikawa, Shigetaka Noma, Soushin Inoue, Yuji Sato, Shun Kohsaka, Keiichi Fukuda

ABSTRACT

Periprocedural myocardial infarction (pMI) is an important complication associated with percutaneous coronary intervention (PCI). However, data on the frequency of biomarker testing and the incidence of pMI remain unclear. Using the multicenter Japan Cardiovascular Database, we identified 2182 patients who underwent PCI without preprocedural cardiac biomarker elevation (silent ischemia, stable angina, or unstable angina without biomarker elevation) from September 2008 to August 2011. Of these, 550 patients (25.2 %) underwent cardiac biomarker testing within 6–24 h after PCI. The incidence of pMI was 2.7 % among all identified patients and 7.5 % among those who underwent cardiac marker testing. Of note, cardiac biomarker testing was performed more frequently than no testing in patients with a higher risk profile such as unstable angina (32.7 vs 24.7 %, P < 0.001), higher symptom scaling (28.2 vs 22.5 %, P = 0.008), urgent or emergent procedures (19.3 vs 15.0 %, P = 0.022 or 4.2 vs 1.0 %, P < 0.001, respectively), and type C lesion (31.3 vs 25.2 %, P = 0.006). Presentation with silent ischemia (odds ratio = 1.51, 95 % confidence interval (CI) 1.16–1.97) and nonemergent PCIs (odds ratio = 3.45, 95 % CI 1.79–6.67) were associated with no postprocedural cardiac biomarker testing. The real-world multicenter PCI registry in Japan revealed an incidence of 2.7 % for pMI; however, cardiac biomarkers were assessed in only 25.2 % of patients after PCI. The results suggest an underuse of postprocedural biomarker testing and room for procedural quality improvement, particularly in cases of silent ischemia and nonemergent cases. More... »

PAGES

714-719

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00380-012-0314-x

DOI

http://dx.doi.org/10.1007/s00380-012-0314-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018247521

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23274577


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58 frequency
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61 improvement
62 incidence
63 incidence of PMI
64 infarction
65 intervention
66 ischemia
67 lesions
68 marker testing
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71 myocardial infarction
72 nonemergent cases
73 nonemergent percutaneous coronary intervention
74 note
75 patients
76 percutaneous coronary intervention
77 periprocedural myocardial infarction
78 procedure
79 profile
80 quality improvement
81 registry
82 results
83 risk profile
84 room
85 scaling
86 silent ischemia
87 testing
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