Evaluation of the effect of urethroplasty for anterior urethral strictures by a validated disease-specific patient-reported outcome measure View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-10-25

AUTHORS

Akio Horiguchi, Masayuki Shinchi, Kenichiro Ojima, Ayako Masunaga, Keiichi Ito, Tomohiko Asano, Eiji Takahashi, Fumihiro Kimura, Ryuichi Azuma

ABSTRACT

PurposeTo better understand our urethroplasty outcome, we translated the English version of a urethral stricture surgery patient-reported outcome measure (USS-PROM) into Japanese and used it to evaluate the effect of urethroplasty for anterior urethral strictures.MethodsThe PROM quantifies lower urinary tract symptoms (LUTS) and health-related quality of life (EQ-5D), and it evaluates overall satisfaction by asking patients to choose “very satisfied”, “satisfied”, “unsatisfied”, or “very unsatisfied”. 93 Japanese-speaking male patients with anterior urethral stricture who underwent urethroplasty completed it before (baseline) and 6 months after urethroplasty. The psychometric criteria evaluated in the present study were the PROM’s internal consistency, test–retest reliability, criterion validity, and responsiveness.ResultsQmax was negatively correlated with the LUTS-total scores (r = − 0.61). Cronbach’s alpha was 0.80 and the test–retest intraclass correlation coefficient for the LUTS-total score was 0.82. 83 patients (89.2%) achieved stricture-free, which was defined as no re-stricture on cystoscopy and no need for additional treatment. The mean total LUTS-score improved from 12.4 at baseline to 3.7 postoperatively (p < 0.0001). The mean EQ-5D visual analogue scores and EQ-5D index improved from 61.2 and 0.76, respectively, at baseline to 77.9 and 0.89 postoperatively (p < 0.0001, p < 0.0001). 55 patients (59.1%) were “very satisfied” with the outcome of their urethroplasty and 33 (35.5%) were “satisfied”.ConclusionsThe Japanese version of the USS-PROM has adequate psychometric properties. Urethroplasty improved not only objective data but also voiding symptoms and health-related QOL, and it resulted in a high rate of patient satisfaction. More... »

PAGES

601-606

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00345-018-2540-z

DOI

http://dx.doi.org/10.1007/s00345-018-2540-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107848901

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30361955


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