Vascular-targeted photodynamic therapy with TOOKAD® Soluble in localized prostate cancer: standardization of the procedure View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-07

AUTHORS

Abdel-Rahmene Azzouzi, Souhil Lebdai, Fawzi Benzaghou, Christian Stief

ABSTRACT

INTRODUCTION: Vascular-targeted photodynamic therapy with TOOKAD(®) Soluble is an innovative focal therapy procedure assessed in localized prostate cancer treatment. MATERIALS AND METHODS: This mini-invasive technique destroys targeted tissues using a photosensitizer [TOOKAD(®) Soluble (WST11), STEBA Biotech] activated by laser light in the presence of oxygen. Its application for prostate cancer requires intravenous infusion of TOOKAD(®) Soluble and the illumination of the targeted area by transperineal optical fibers inserted under trans-rectal ultrasound guidance under general anesthesia. CONCLUSION: Based on the experience gained through hundreds of procedures, we describe here the standardized technique of vascular-targeted photodynamic therapy with TOOKAD(®) Soluble defined during the phase II and III trials. More... »

PAGES

937-944

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00345-015-1535-2

DOI

http://dx.doi.org/10.1007/s00345-015-1535-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052299351

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25786708


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