The natural course of pT2 prostate cancer with positive surgical margin: predicting biochemical recurrence View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-07

AUTHORS

A. Karl, A. Buchner, C. Tympner, T. Kirchner, U. Ganswindt, C. Belka, R. Ganzer, M. Burger, F. Eder, F. Hofstädter, D. Schilling, K. Sievert, A. Stenzl, M. Scharpf, F. Fend, F. vom Dorp, H. Rübben, K. Schmid, D. Porres-Knoblauch, A. Heidenreich, B. Hangarter, R. Knüchel-Clarke, M. Rogenhofer, B. Wullich, A. Hartmann, E. Comploj, A. Pycha, E. Hanspeter, D. Pehrke, G. Sauter, M. Graefen, C. Stief, A. Haese

ABSTRACT

PURPOSE: To predict biochemical recurrence respecting the natural course of pT2 prostate cancer with positive surgical margin (R1) and no adjuvant/neoadjuvant therapy. METHODS: A multicenter data analysis of 956 patients with pT2R1N0/Nx tumors was performed. Patients underwent radical prostatectomy between 1994 and 2009. No patients received neoadjuvant or adjuvant therapy. All prostate specimens were re-evaluated according to a well-defined protocol. The association of pathological and clinical features, in regard to BCR, was calculated using various statistical tests. RESULTS: With a mean follow-up of 48 months, BCR was found in 25.4 %. In univariate analysis, multiple parameters such as tumor volume, PSA, Gleason at positive margin were significantly associated with BCR. However, in multivariate analysis, Gleason score (GS) of the prostatectomy specimen was the only significant parameter for BCR. Median time to recurrence for GS ≤ 6 was not reached; 5-year BCR-free survival was 82 %; and they were 127 months and 72 % for GS 3+4, 56 months and 54 % for GS 4 + 3, and 27 months and 32 % for GS 8-10. The retrospective approach is a limitation of our study. CONCLUSIONS: Our study provides data on the BCR in pT2R1-PCa without adjuvant/neoadjuvant therapy and thus a rationale for an individual's risk stratification. The data support patients and physicians in estimating the individual risk and timing of BCR and thus serve to personalize the management in pT2R1-PCa. More... »

PAGES

973-979

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00345-015-1510-y

DOI

http://dx.doi.org/10.1007/s00345-015-1510-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029436864

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25682109


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kallikreins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Grading", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Recurrence, Local", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm, Residual", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prostate-Specific Antigen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prostatectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prostatic Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, 81377, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Karl", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, 81377, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Buchner", 
        "givenName": "A.", 
        "id": "sg:person.0603274241.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603274241.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Pathology, Ludwig-Maximilians-University, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tympner", 
        "givenName": "C.", 
        "id": "sg:person.01033427770.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033427770.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Pathology, Ludwig-Maximilians-University, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kirchner", 
        "givenName": "T.", 
        "id": "sg:person.0650074000.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650074000.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Radiation Oncology, Ludwig-Maximilians-University, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ganswindt", 
        "givenName": "U.", 
        "id": "sg:person.01127253114.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127253114.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Radiation Oncology, Ludwig-Maximilians-University, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Belka", 
        "givenName": "C.", 
        "id": "sg:person.0632042327.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632042327.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Regensburg", 
          "id": "https://www.grid.ac/institutes/grid.7727.5", 
          "name": [
            "Department of Urology, University Regensburg, Regensburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ganzer", 
        "givenName": "R.", 
        "id": "sg:person.01073642445.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073642445.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Regensburg", 
          "id": "https://www.grid.ac/institutes/grid.7727.5", 
          "name": [
            "Department of Urology, University Regensburg, Regensburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Burger", 
        "givenName": "M.", 
        "id": "sg:person.014475444302.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014475444302.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Regensburg", 
          "id": "https://www.grid.ac/institutes/grid.7727.5", 
          "name": [
            "Department of Pathology, University Regensburg, Regensburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eder", 
        "givenName": "F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Regensburg", 
          "id": "https://www.grid.ac/institutes/grid.7727.5", 
          "name": [
            "Department of Pathology, University Regensburg, Regensburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hofst\u00e4dter", 
        "givenName": "F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of T\u00fcbingen", 
          "id": "https://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Urology, University T\u00fcbingen, T\u00fcbingen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schilling", 
        "givenName": "D.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of T\u00fcbingen", 
          "id": "https://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Urology, University T\u00fcbingen, T\u00fcbingen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sievert", 
        "givenName": "K.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of T\u00fcbingen", 
          "id": "https://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Urology, University T\u00fcbingen, T\u00fcbingen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stenzl", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of T\u00fcbingen", 
          "id": "https://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Pathology, University T\u00fcbingen, T\u00fcbingen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scharpf", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of T\u00fcbingen", 
          "id": "https://www.grid.ac/institutes/grid.10392.39", 
          "name": [
            "Department of Pathology, University T\u00fcbingen, T\u00fcbingen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fend", 
        "givenName": "F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Duisburg-Essen", 
          "id": "https://www.grid.ac/institutes/grid.5718.b", 
          "name": [
            "Department of Urology, University Essen, Essen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "vom Dorp", 
        "givenName": "F.", 
        "id": "sg:person.010166200775.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010166200775.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Duisburg-Essen", 
          "id": "https://www.grid.ac/institutes/grid.5718.b", 
          "name": [
            "Department of Urology, University Essen, Essen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "R\u00fcbben", 
        "givenName": "H.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Duisburg-Essen", 
          "id": "https://www.grid.ac/institutes/grid.5718.b", 
          "name": [
            "Department of Pathology, University Essen, Essen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schmid", 
        "givenName": "K.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "RWTH Aachen University", 
          "id": "https://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Department of Urology, University RWTH Aachen, Aachen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Porres-Knoblauch", 
        "givenName": "D.", 
        "id": "sg:person.01267277566.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267277566.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "RWTH Aachen University", 
          "id": "https://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Department of Urology, University RWTH Aachen, Aachen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heidenreich", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "RWTH Aachen University", 
          "id": "https://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Department of Pathology, University RWTH Aachen, Aachen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hangarter", 
        "givenName": "B.", 
        "id": "sg:person.01154141435.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154141435.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "RWTH Aachen University", 
          "id": "https://www.grid.ac/institutes/grid.1957.a", 
          "name": [
            "Department of Pathology, University RWTH Aachen, Aachen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kn\u00fcchel-Clarke", 
        "givenName": "R.", 
        "id": "sg:person.01017252364.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017252364.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Urology, Friedrich-Alexander University Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rogenhofer", 
        "givenName": "M.", 
        "id": "sg:person.01270370035.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270370035.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Urology, Friedrich-Alexander University Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wullich", 
        "givenName": "B.", 
        "id": "sg:person.0603206233.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603206233.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Erlangen-Nuremberg", 
          "id": "https://www.grid.ac/institutes/grid.5330.5", 
          "name": [
            "Department of Pathology, Friedrich-Alexander University Erlangen-N\u00fcrnberg, Erlangen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hartmann", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Urology, Zentralkrankenhaus Bozen, Bozen, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Comploj", 
        "givenName": "E.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Urology, Zentralkrankenhaus Bozen, Bozen, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pycha", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pathology, Zentralkrankenhaus Bozen, Bozen, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hanspeter", 
        "givenName": "E.", 
        "id": "sg:person.0650767253.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650767253.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Hamburg-Eppendorf", 
          "id": "https://www.grid.ac/institutes/grid.13648.38", 
          "name": [
            "Martini-Klinik am UKE, University Clinic Hamburg-Eppendorf, Hamburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pehrke", 
        "givenName": "D.", 
        "id": "sg:person.0767260245.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767260245.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Hamburg-Eppendorf", 
          "id": "https://www.grid.ac/institutes/grid.13648.38", 
          "name": [
            "Department of Pathology, UKE, Hamburg-Eppendorf, Hamburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sauter", 
        "givenName": "G.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Hamburg-Eppendorf", 
          "id": "https://www.grid.ac/institutes/grid.13648.38", 
          "name": [
            "Martini-Klinik am UKE, University Clinic Hamburg-Eppendorf, Hamburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Graefen", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, 81377, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stief", 
        "givenName": "C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Hamburg-Eppendorf", 
          "id": "https://www.grid.ac/institutes/grid.13648.38", 
          "name": [
            "Martini-Klinik am UKE, University Clinic Hamburg-Eppendorf, Hamburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Haese", 
        "givenName": "A.", 
        "id": "sg:person.01272063277.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272063277.51"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2011.10.069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001524424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/03008880510030932", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002921454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.eururo.2012.04.056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003752676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2013.06.2053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005370539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2007.10.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006197952"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2006.09.6495", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008793712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2009.02.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009225235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.juro.2009.11.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017767823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2011.10.077", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019542062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2006.10.4067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020187960"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.eururo.2013.08.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021966072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2007.04.068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024942015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.eururo.2011.04.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026384733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5347(05)67511-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027357361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2011.10.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032902415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2009.02.049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036006598"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)67101-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036045722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)67101-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036045722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.juro.2009.08.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037591623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2007.07.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038586095"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2006.04.029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039917504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.18.9563", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040695532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.eururo.2013.08.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050145518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.eururo.2011.08.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050549939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074665594", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-07", 
    "datePublishedReg": "2015-07-01", 
    "description": "PURPOSE: To predict biochemical recurrence respecting the natural course of pT2 prostate cancer with positive surgical margin (R1) and no adjuvant/neoadjuvant therapy.\nMETHODS: A multicenter data analysis of 956 patients with pT2R1N0/Nx tumors was performed. Patients underwent radical prostatectomy between 1994 and 2009. No patients received neoadjuvant or adjuvant therapy. All prostate specimens were re-evaluated according to a well-defined protocol. The association of pathological and clinical features, in regard to BCR, was calculated using various statistical tests.\nRESULTS: With a mean follow-up of 48 months, BCR was found in 25.4 %. In univariate analysis, multiple parameters such as tumor volume, PSA, Gleason at positive margin were significantly associated with BCR. However, in multivariate analysis, Gleason score (GS) of the prostatectomy specimen was the only significant parameter for BCR. Median time to recurrence for GS \u2264 6 was not reached; 5-year BCR-free survival was 82 %; and they were 127 months and 72 % for GS 3+4, 56 months and 54 % for GS 4 + 3, and 27 months and 32 % for GS 8-10. The retrospective approach is a limitation of our study.\nCONCLUSIONS: Our study provides data on the BCR in pT2R1-PCa without adjuvant/neoadjuvant therapy and thus a rationale for an individual's risk stratification. The data support patients and physicians in estimating the individual risk and timing of BCR and thus serve to personalize the management in pT2R1-PCa.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00345-015-1510-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1094127", 
        "issn": [
          "0724-4983", 
          "1433-8726"
        ], 
        "name": "World Journal of Urology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "33"
      }
    ], 
    "name": "The natural course of pT2 prostate cancer with positive surgical margin: predicting biochemical recurrence", 
    "pagination": "973-979", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8c3b527e57394694ed6a15b01886f6414ef52b423c5471ed9f52e0fde7130fd1"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25682109"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8307716"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00345-015-1510-y"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1029436864"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00345-015-1510-y", 
      "https://app.dimensions.ai/details/publication/pub.1029436864"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:10", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000513.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00345-015-1510-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00345-015-1510-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00345-015-1510-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00345-015-1510-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00345-015-1510-y'


 

This table displays all metadata directly associated to this object as RDF triples.

439 TRIPLES      21 PREDICATES      68 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00345-015-1510-y schema:about N1bd63fb40f624ae5ac4bf8c354771bb7
2 N1f743fa48e1f4ba9b89a0e534005d875
3 N2fc6b148c91d4593aa63083bcb91a6e3
4 N441fd73814234302bd7ccb072bd8b642
5 N4979d71d095544259bc90bfcf24a2480
6 N4f033e5e7b9e45229bc1096a5fb19935
7 N5626fcc2525c42cd9cef5cb7ebd7a645
8 N846639baa1ce429cb36f540aa0ce712f
9 N98d0906e9ae247edbee0868f14d04d15
10 Nb1a064baf0c44a0983ff21cf2fabde73
11 Nb87fa002bb474a5b934bccf9a0169f53
12 Nc4ec538d761844ce852115b52e72def4
13 Nd00b6296b3e24cc0b55b0f6ec5667887
14 Ne599e61726d4490ab9214f28b1470c52
15 Nff1cfa4df0cc4b57922d7b2435144cc7
16 anzsrc-for:11
17 anzsrc-for:1112
18 schema:author Nd0b4d65ca80c41b19a8837de2ffb43b9
19 schema:citation https://app.dimensions.ai/details/publication/pub.1074665594
20 https://doi.org/10.1016/j.eururo.2011.04.021
21 https://doi.org/10.1016/j.eururo.2011.08.006
22 https://doi.org/10.1016/j.eururo.2012.04.056
23 https://doi.org/10.1016/j.eururo.2013.08.013
24 https://doi.org/10.1016/j.eururo.2013.08.036
25 https://doi.org/10.1016/j.ijrobp.2006.04.029
26 https://doi.org/10.1016/j.ijrobp.2007.04.068
27 https://doi.org/10.1016/j.ijrobp.2007.10.008
28 https://doi.org/10.1016/j.ijrobp.2009.02.006
29 https://doi.org/10.1016/j.ijrobp.2009.02.049
30 https://doi.org/10.1016/j.ijrobp.2011.10.069
31 https://doi.org/10.1016/j.ijrobp.2011.10.077
32 https://doi.org/10.1016/j.ijrobp.2013.06.2053
33 https://doi.org/10.1016/j.juro.2009.08.027
34 https://doi.org/10.1016/j.juro.2009.11.039
35 https://doi.org/10.1016/j.radonc.2007.07.017
36 https://doi.org/10.1016/j.radonc.2011.10.024
37 https://doi.org/10.1016/s0022-5347(05)67511-8
38 https://doi.org/10.1016/s0140-6736(05)67101-2
39 https://doi.org/10.1080/03008880510030932
40 https://doi.org/10.1200/jco.2006.09.6495
41 https://doi.org/10.1200/jco.2006.10.4067
42 https://doi.org/10.1200/jco.2008.18.9563
43 schema:datePublished 2015-07
44 schema:datePublishedReg 2015-07-01
45 schema:description PURPOSE: To predict biochemical recurrence respecting the natural course of pT2 prostate cancer with positive surgical margin (R1) and no adjuvant/neoadjuvant therapy. METHODS: A multicenter data analysis of 956 patients with pT2R1N0/Nx tumors was performed. Patients underwent radical prostatectomy between 1994 and 2009. No patients received neoadjuvant or adjuvant therapy. All prostate specimens were re-evaluated according to a well-defined protocol. The association of pathological and clinical features, in regard to BCR, was calculated using various statistical tests. RESULTS: With a mean follow-up of 48 months, BCR was found in 25.4 %. In univariate analysis, multiple parameters such as tumor volume, PSA, Gleason at positive margin were significantly associated with BCR. However, in multivariate analysis, Gleason score (GS) of the prostatectomy specimen was the only significant parameter for BCR. Median time to recurrence for GS ≤ 6 was not reached; 5-year BCR-free survival was 82 %; and they were 127 months and 72 % for GS 3+4, 56 months and 54 % for GS 4 + 3, and 27 months and 32 % for GS 8-10. The retrospective approach is a limitation of our study. CONCLUSIONS: Our study provides data on the BCR in pT2R1-PCa without adjuvant/neoadjuvant therapy and thus a rationale for an individual's risk stratification. The data support patients and physicians in estimating the individual risk and timing of BCR and thus serve to personalize the management in pT2R1-PCa.
46 schema:genre research_article
47 schema:inLanguage en
48 schema:isAccessibleForFree false
49 schema:isPartOf N05f0502f72f1487cbcbc2a377f3dd3ca
50 N6c45048187254af89e5785ba1b05dd0a
51 sg:journal.1094127
52 schema:name The natural course of pT2 prostate cancer with positive surgical margin: predicting biochemical recurrence
53 schema:pagination 973-979
54 schema:productId N6d7b785f3bd64220aa3b3c86f317a9ed
55 N70bae746d4f144d38677c45685438f84
56 N92d91046846442798a52dc9a6506b74f
57 Na4d26b01db66439497c7d9b3a483f4cc
58 Nba0dad17b7e24b0fae474864a283726b
59 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029436864
60 https://doi.org/10.1007/s00345-015-1510-y
61 schema:sdDatePublished 2019-04-10T14:10
62 schema:sdLicense https://scigraph.springernature.com/explorer/license/
63 schema:sdPublisher N281ae102e721489a878c04c467329c39
64 schema:url http://link.springer.com/10.1007%2Fs00345-015-1510-y
65 sgo:license sg:explorer/license/
66 sgo:sdDataset articles
67 rdf:type schema:ScholarlyArticle
68 N0557a1a4708c48f393ce9353306ca47b rdf:first N6239398c3b834d759f2138e7fa80d586
69 rdf:rest N4d43c01bac654681baffefe041b032b7
70 N05f0502f72f1487cbcbc2a377f3dd3ca schema:volumeNumber 33
71 rdf:type schema:PublicationVolume
72 N08b2475ca4864a52bca06ed1d857adee rdf:first sg:person.0767260245.53
73 rdf:rest N6b245b7b7dbc43d5959dcdd0cb2e47b8
74 N0af7df3300a341e9839072a7449f60d4 rdf:first Ne4dcf43defc64df881c184b426a8971a
75 rdf:rest N4291438d353049c3ab917c5d4ec5ff0f
76 N0b055a56d56d43548e50a0768011fa47 rdf:first sg:person.01033427770.68
77 rdf:rest N84780f2a9e8242718f599a1ab0f70b28
78 N0bbe2d37bba84fcbb1c5d175ef6003aa schema:name Department of Urology, Zentralkrankenhaus Bozen, Bozen, Italy
79 rdf:type schema:Organization
80 N1bd63fb40f624ae5ac4bf8c354771bb7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Neoplasm Grading
82 rdf:type schema:DefinedTerm
83 N1ebd152278664874bc5082fcb88f33fd schema:affiliation https://www.grid.ac/institutes/grid.10392.39
84 schema:familyName Sievert
85 schema:givenName K.
86 rdf:type schema:Person
87 N1f743fa48e1f4ba9b89a0e534005d875 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Treatment Outcome
89 rdf:type schema:DefinedTerm
90 N1fcf9f68626a41c6972fce308cc1a72b rdf:first N1ebd152278664874bc5082fcb88f33fd
91 rdf:rest Nfded322e31fc4f56a91f94a8953367e5
92 N281ae102e721489a878c04c467329c39 schema:name Springer Nature - SN SciGraph project
93 rdf:type schema:Organization
94 N2a5a51d4cf06407d8c1d176c835ed485 rdf:first sg:person.0603206233.14
95 rdf:rest N98140d8d3f2e4b35a89b80a860749ce6
96 N2b4b825b0f9d4f68af34f62b42d39db4 schema:affiliation https://www.grid.ac/institutes/grid.5718.b
97 schema:familyName Rübben
98 schema:givenName H.
99 rdf:type schema:Person
100 N2fc6b148c91d4593aa63083bcb91a6e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Prostatic Neoplasms
102 rdf:type schema:DefinedTerm
103 N35a5000db3414de49e886f2359d7b73a schema:affiliation https://www.grid.ac/institutes/grid.5330.5
104 schema:familyName Hartmann
105 schema:givenName A.
106 rdf:type schema:Person
107 N36acba439d724952bf47a937f72d647c rdf:first Nfba0944e5dfc46749b56ea38068641c8
108 rdf:rest N0af7df3300a341e9839072a7449f60d4
109 N4291438d353049c3ab917c5d4ec5ff0f rdf:first Nfbf2f928a09d45378bd30c061350d891
110 rdf:rest N1fcf9f68626a41c6972fce308cc1a72b
111 N43be3ef97efb4d93bec8f50c7da0a28a rdf:first sg:person.01270370035.35
112 rdf:rest N2a5a51d4cf06407d8c1d176c835ed485
113 N441fd73814234302bd7ccb072bd8b642 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Retrospective Studies
115 rdf:type schema:DefinedTerm
116 N48251bbe7843475c895f0885d33d94b7 schema:name Department of Pathology, Zentralkrankenhaus Bozen, Bozen, Italy
117 rdf:type schema:Organization
118 N4979d71d095544259bc90bfcf24a2480 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Neoplasm Recurrence, Local
120 rdf:type schema:DefinedTerm
121 N4aa5ffbe54e5455aab29ce38348e8dd4 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
122 schema:familyName Stief
123 schema:givenName C.
124 rdf:type schema:Person
125 N4b7be54865d54b898f4bfe96423a5c74 rdf:first N4c1cccffd9604a41988932105e5a0693
126 rdf:rest N85e2e3b54c4144308132842bfb337e3a
127 N4c1cccffd9604a41988932105e5a0693 schema:affiliation https://www.grid.ac/institutes/grid.1957.a
128 schema:familyName Heidenreich
129 schema:givenName A.
130 rdf:type schema:Person
131 N4d43c01bac654681baffefe041b032b7 rdf:first sg:person.010166200775.44
132 rdf:rest Ndc4cf69d040c4ce6b60f4be7a129308f
133 N4f033e5e7b9e45229bc1096a5fb19935 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Neoplasm Staging
135 rdf:type schema:DefinedTerm
136 N55064574d7cb4c0aa3cc99a5874b32dd schema:name Department of Urology, Zentralkrankenhaus Bozen, Bozen, Italy
137 rdf:type schema:Organization
138 N5626fcc2525c42cd9cef5cb7ebd7a645 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Male
140 rdf:type schema:DefinedTerm
141 N6239398c3b834d759f2138e7fa80d586 schema:affiliation https://www.grid.ac/institutes/grid.10392.39
142 schema:familyName Fend
143 schema:givenName F.
144 rdf:type schema:Person
145 N6b245b7b7dbc43d5959dcdd0cb2e47b8 rdf:first Neaffc0a9512143c2b84f5dca5dff070a
146 rdf:rest Ne66d90510a224147a3c2107e99771038
147 N6baf03881eb1449795ff8f64feda2f6c schema:affiliation https://www.grid.ac/institutes/grid.5252.0
148 schema:familyName Karl
149 schema:givenName A.
150 rdf:type schema:Person
151 N6c45048187254af89e5785ba1b05dd0a schema:issueNumber 7
152 rdf:type schema:PublicationIssue
153 N6d7b785f3bd64220aa3b3c86f317a9ed schema:name nlm_unique_id
154 schema:value 8307716
155 rdf:type schema:PropertyValue
156 N6de26fb0fd70458d8628e290461f218e rdf:first sg:person.0632042327.96
157 rdf:rest Nada3db2aeb5849b79df3006c40b84427
158 N70bae746d4f144d38677c45685438f84 schema:name pubmed_id
159 schema:value 25682109
160 rdf:type schema:PropertyValue
161 N74a0dfe706024963ac27705920e3f915 schema:affiliation N55064574d7cb4c0aa3cc99a5874b32dd
162 schema:familyName Comploj
163 schema:givenName E.
164 rdf:type schema:Person
165 N836ff11540374de49085d971fe46bc0d rdf:first sg:person.014475444302.62
166 rdf:rest N36acba439d724952bf47a937f72d647c
167 N846639baa1ce429cb36f540aa0ce712f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Humans
169 rdf:type schema:DefinedTerm
170 N84780f2a9e8242718f599a1ab0f70b28 rdf:first sg:person.0650074000.01
171 rdf:rest Ne50f061c7c80427f9b2b67a72dd37fa8
172 N85e2e3b54c4144308132842bfb337e3a rdf:first sg:person.01154141435.45
173 rdf:rest Nd94742de4aea45da9d49628be51eadb2
174 N92d91046846442798a52dc9a6506b74f schema:name dimensions_id
175 schema:value pub.1029436864
176 rdf:type schema:PropertyValue
177 N960c77fee27d4d7cafb1c2519983c15a rdf:first Ncb07ff15e7704c769837c625fa9b3336
178 rdf:rest Nd1d378e78c934e51a9ad03bbd4d692d5
179 N98140d8d3f2e4b35a89b80a860749ce6 rdf:first N35a5000db3414de49e886f2359d7b73a
180 rdf:rest Naa96399901104ccea8beb4297bf480a6
181 N98d0906e9ae247edbee0868f14d04d15 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Neoplasm, Residual
183 rdf:type schema:DefinedTerm
184 N9c575ce85eb141c197a6d0d8f2ec7350 schema:affiliation https://www.grid.ac/institutes/grid.10392.39
185 schema:familyName Stenzl
186 schema:givenName A.
187 rdf:type schema:Person
188 Na4d26b01db66439497c7d9b3a483f4cc schema:name readcube_id
189 schema:value 8c3b527e57394694ed6a15b01886f6414ef52b423c5471ed9f52e0fde7130fd1
190 rdf:type schema:PropertyValue
191 Na8b25ac77c37439ab89c56c32efcd9d7 rdf:first Nbc33df68dca24fc88347f408b8180569
192 rdf:rest N0557a1a4708c48f393ce9353306ca47b
193 Naa96399901104ccea8beb4297bf480a6 rdf:first N74a0dfe706024963ac27705920e3f915
194 rdf:rest N960c77fee27d4d7cafb1c2519983c15a
195 Nada3db2aeb5849b79df3006c40b84427 rdf:first sg:person.01073642445.24
196 rdf:rest N836ff11540374de49085d971fe46bc0d
197 Nb1a064baf0c44a0983ff21cf2fabde73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
198 schema:name Prostate-Specific Antigen
199 rdf:type schema:DefinedTerm
200 Nb87fa002bb474a5b934bccf9a0169f53 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
201 schema:name Adult
202 rdf:type schema:DefinedTerm
203 Nba0dad17b7e24b0fae474864a283726b schema:name doi
204 schema:value 10.1007/s00345-015-1510-y
205 rdf:type schema:PropertyValue
206 Nba4f10f36bef458fa260e497db8e5189 schema:affiliation https://www.grid.ac/institutes/grid.13648.38
207 schema:familyName Graefen
208 schema:givenName M.
209 rdf:type schema:Person
210 Nbc33df68dca24fc88347f408b8180569 schema:affiliation https://www.grid.ac/institutes/grid.10392.39
211 schema:familyName Scharpf
212 schema:givenName M.
213 rdf:type schema:Person
214 Nc4ec538d761844ce852115b52e72def4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
215 schema:name Prostatectomy
216 rdf:type schema:DefinedTerm
217 Nc942e47b7b984278822c14021366495a rdf:first sg:person.0603274241.39
218 rdf:rest N0b055a56d56d43548e50a0768011fa47
219 Ncb07ff15e7704c769837c625fa9b3336 schema:affiliation N0bbe2d37bba84fcbb1c5d175ef6003aa
220 schema:familyName Pycha
221 schema:givenName A.
222 rdf:type schema:Person
223 Ncf17efe8045545a981f9a0087ef261fa rdf:first N4aa5ffbe54e5455aab29ce38348e8dd4
224 rdf:rest Nd616262ee2144de7b53c55a9b27025ac
225 Nd00b6296b3e24cc0b55b0f6ec5667887 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
226 schema:name Kallikreins
227 rdf:type schema:DefinedTerm
228 Nd0b4d65ca80c41b19a8837de2ffb43b9 rdf:first N6baf03881eb1449795ff8f64feda2f6c
229 rdf:rest Nc942e47b7b984278822c14021366495a
230 Nd1d378e78c934e51a9ad03bbd4d692d5 rdf:first sg:person.0650767253.43
231 rdf:rest N08b2475ca4864a52bca06ed1d857adee
232 Nd616262ee2144de7b53c55a9b27025ac rdf:first sg:person.01272063277.51
233 rdf:rest rdf:nil
234 Nd94742de4aea45da9d49628be51eadb2 rdf:first sg:person.01017252364.20
235 rdf:rest N43be3ef97efb4d93bec8f50c7da0a28a
236 Ndc4cf69d040c4ce6b60f4be7a129308f rdf:first N2b4b825b0f9d4f68af34f62b42d39db4
237 rdf:rest Nee2ee4c657cd408b842c192d1480f13b
238 Nde3955b72f794cf3bbbd7914ef160b82 rdf:first sg:person.01267277566.97
239 rdf:rest N4b7be54865d54b898f4bfe96423a5c74
240 Ne4dcf43defc64df881c184b426a8971a schema:affiliation https://www.grid.ac/institutes/grid.7727.5
241 schema:familyName Hofstädter
242 schema:givenName F.
243 rdf:type schema:Person
244 Ne50f061c7c80427f9b2b67a72dd37fa8 rdf:first sg:person.01127253114.17
245 rdf:rest N6de26fb0fd70458d8628e290461f218e
246 Ne599e61726d4490ab9214f28b1470c52 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
247 schema:name Aged
248 rdf:type schema:DefinedTerm
249 Ne66d90510a224147a3c2107e99771038 rdf:first Nba4f10f36bef458fa260e497db8e5189
250 rdf:rest Ncf17efe8045545a981f9a0087ef261fa
251 Neaffc0a9512143c2b84f5dca5dff070a schema:affiliation https://www.grid.ac/institutes/grid.13648.38
252 schema:familyName Sauter
253 schema:givenName G.
254 rdf:type schema:Person
255 Nee2ee4c657cd408b842c192d1480f13b rdf:first Nfe0c33f9416942ed8bbef6cb34c3f312
256 rdf:rest Nde3955b72f794cf3bbbd7914ef160b82
257 Nfba0944e5dfc46749b56ea38068641c8 schema:affiliation https://www.grid.ac/institutes/grid.7727.5
258 schema:familyName Eder
259 schema:givenName F.
260 rdf:type schema:Person
261 Nfbf2f928a09d45378bd30c061350d891 schema:affiliation https://www.grid.ac/institutes/grid.10392.39
262 schema:familyName Schilling
263 schema:givenName D.
264 rdf:type schema:Person
265 Nfded322e31fc4f56a91f94a8953367e5 rdf:first N9c575ce85eb141c197a6d0d8f2ec7350
266 rdf:rest Na8b25ac77c37439ab89c56c32efcd9d7
267 Nfe0c33f9416942ed8bbef6cb34c3f312 schema:affiliation https://www.grid.ac/institutes/grid.5718.b
268 schema:familyName Schmid
269 schema:givenName K.
270 rdf:type schema:Person
271 Nff1cfa4df0cc4b57922d7b2435144cc7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
272 schema:name Middle Aged
273 rdf:type schema:DefinedTerm
274 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
275 schema:name Medical and Health Sciences
276 rdf:type schema:DefinedTerm
277 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
278 schema:name Oncology and Carcinogenesis
279 rdf:type schema:DefinedTerm
280 sg:journal.1094127 schema:issn 0724-4983
281 1433-8726
282 schema:name World Journal of Urology
283 rdf:type schema:Periodical
284 sg:person.010166200775.44 schema:affiliation https://www.grid.ac/institutes/grid.5718.b
285 schema:familyName vom Dorp
286 schema:givenName F.
287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010166200775.44
288 rdf:type schema:Person
289 sg:person.01017252364.20 schema:affiliation https://www.grid.ac/institutes/grid.1957.a
290 schema:familyName Knüchel-Clarke
291 schema:givenName R.
292 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017252364.20
293 rdf:type schema:Person
294 sg:person.01033427770.68 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
295 schema:familyName Tympner
296 schema:givenName C.
297 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033427770.68
298 rdf:type schema:Person
299 sg:person.01073642445.24 schema:affiliation https://www.grid.ac/institutes/grid.7727.5
300 schema:familyName Ganzer
301 schema:givenName R.
302 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073642445.24
303 rdf:type schema:Person
304 sg:person.01127253114.17 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
305 schema:familyName Ganswindt
306 schema:givenName U.
307 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127253114.17
308 rdf:type schema:Person
309 sg:person.01154141435.45 schema:affiliation https://www.grid.ac/institutes/grid.1957.a
310 schema:familyName Hangarter
311 schema:givenName B.
312 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154141435.45
313 rdf:type schema:Person
314 sg:person.01267277566.97 schema:affiliation https://www.grid.ac/institutes/grid.1957.a
315 schema:familyName Porres-Knoblauch
316 schema:givenName D.
317 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267277566.97
318 rdf:type schema:Person
319 sg:person.01270370035.35 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
320 schema:familyName Rogenhofer
321 schema:givenName M.
322 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270370035.35
323 rdf:type schema:Person
324 sg:person.01272063277.51 schema:affiliation https://www.grid.ac/institutes/grid.13648.38
325 schema:familyName Haese
326 schema:givenName A.
327 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272063277.51
328 rdf:type schema:Person
329 sg:person.014475444302.62 schema:affiliation https://www.grid.ac/institutes/grid.7727.5
330 schema:familyName Burger
331 schema:givenName M.
332 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014475444302.62
333 rdf:type schema:Person
334 sg:person.0603206233.14 schema:affiliation https://www.grid.ac/institutes/grid.5330.5
335 schema:familyName Wullich
336 schema:givenName B.
337 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603206233.14
338 rdf:type schema:Person
339 sg:person.0603274241.39 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
340 schema:familyName Buchner
341 schema:givenName A.
342 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603274241.39
343 rdf:type schema:Person
344 sg:person.0632042327.96 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
345 schema:familyName Belka
346 schema:givenName C.
347 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632042327.96
348 rdf:type schema:Person
349 sg:person.0650074000.01 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
350 schema:familyName Kirchner
351 schema:givenName T.
352 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650074000.01
353 rdf:type schema:Person
354 sg:person.0650767253.43 schema:affiliation N48251bbe7843475c895f0885d33d94b7
355 schema:familyName Hanspeter
356 schema:givenName E.
357 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650767253.43
358 rdf:type schema:Person
359 sg:person.0767260245.53 schema:affiliation https://www.grid.ac/institutes/grid.13648.38
360 schema:familyName Pehrke
361 schema:givenName D.
362 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767260245.53
363 rdf:type schema:Person
364 https://app.dimensions.ai/details/publication/pub.1074665594 schema:CreativeWork
365 https://doi.org/10.1016/j.eururo.2011.04.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026384733
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1016/j.eururo.2011.08.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050549939
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1016/j.eururo.2012.04.056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003752676
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1016/j.eururo.2013.08.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021966072
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1016/j.eururo.2013.08.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050145518
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1016/j.ijrobp.2006.04.029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039917504
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1016/j.ijrobp.2007.04.068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024942015
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1016/j.ijrobp.2007.10.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006197952
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1016/j.ijrobp.2009.02.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009225235
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1016/j.ijrobp.2009.02.049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036006598
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1016/j.ijrobp.2011.10.069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001524424
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1016/j.ijrobp.2011.10.077 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019542062
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1016/j.ijrobp.2013.06.2053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005370539
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1016/j.juro.2009.08.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037591623
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1016/j.juro.2009.11.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017767823
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1016/j.radonc.2007.07.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038586095
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1016/j.radonc.2011.10.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032902415
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1016/s0022-5347(05)67511-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027357361
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1016/s0140-6736(05)67101-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036045722
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1080/03008880510030932 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002921454
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1200/jco.2006.09.6495 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008793712
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1200/jco.2006.10.4067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020187960
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1200/jco.2008.18.9563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040695532
410 rdf:type schema:CreativeWork
411 https://www.grid.ac/institutes/grid.10392.39 schema:alternateName University of Tübingen
412 schema:name Department of Pathology, University Tübingen, Tübingen, Germany
413 Department of Urology, University Tübingen, Tübingen, Germany
414 rdf:type schema:Organization
415 https://www.grid.ac/institutes/grid.13648.38 schema:alternateName University Medical Center Hamburg-Eppendorf
416 schema:name Department of Pathology, UKE, Hamburg-Eppendorf, Hamburg, Germany
417 Martini-Klinik am UKE, University Clinic Hamburg-Eppendorf, Hamburg, Germany
418 rdf:type schema:Organization
419 https://www.grid.ac/institutes/grid.1957.a schema:alternateName RWTH Aachen University
420 schema:name Department of Pathology, University RWTH Aachen, Aachen, Germany
421 Department of Urology, University RWTH Aachen, Aachen, Germany
422 rdf:type schema:Organization
423 https://www.grid.ac/institutes/grid.5252.0 schema:alternateName Ludwig Maximilian University of Munich
424 schema:name Department of Pathology, Ludwig-Maximilians-University, Munich, Germany
425 Department of Radiation Oncology, Ludwig-Maximilians-University, Munich, Germany
426 Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, 81377, Munich, Germany
427 rdf:type schema:Organization
428 https://www.grid.ac/institutes/grid.5330.5 schema:alternateName University of Erlangen-Nuremberg
429 schema:name Department of Pathology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany
430 Department of Urology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany
431 rdf:type schema:Organization
432 https://www.grid.ac/institutes/grid.5718.b schema:alternateName University of Duisburg-Essen
433 schema:name Department of Pathology, University Essen, Essen, Germany
434 Department of Urology, University Essen, Essen, Germany
435 rdf:type schema:Organization
436 https://www.grid.ac/institutes/grid.7727.5 schema:alternateName University of Regensburg
437 schema:name Department of Pathology, University Regensburg, Regensburg, Germany
438 Department of Urology, University Regensburg, Regensburg, Germany
439 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...