Significance of ADC value for detection and characterization of urothelial carcinoma of upper urinary tract using diffusion-weighted MRI View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-02

AUTHORS

A. Sufana Iancu, P. Colin, P. Puech, A. Villers, A. Ouzzane, J. C. Fantoni, X. Leroy, L. Lemaitre

ABSTRACT

PURPOSE: To evaluate utility of diffusion-weighted magnetic resonance imaging (DWI) to detect and predict the histological characteristics of upper urinary tract urothelial carcinomas (UTUCs). MATERIALS AND METHODS: We retrospectively evaluated 20 suspicious lesions from 19 patients. MRI study included conventional sequences and DWI with apparent diffusion coefficient (ADC) maps calculated between b = 0 and b = 1,000. ADC values were measured within two different regions of interest (ROI): a small identical ROI placed in the most restrictive part of the tumour and a larger ROI covering two-thirds of the mass surface. The mean ADC values of the tumours were compared with that of normal renal parenchyma using an unpaired Student's t test. Association between ADC values and histological features was tested using non-parametric tests. RESULTS: Overall, 18 tumours were confirmed histologically as UTUCs. DWI failed to detect two cases of UTUCs (one CIS and one small tumour of 5 mm). There was no statistically significant difference in ADC values measured with the small or large ROI (p = 0.134). The mean ADC value of UTUC was significantly lower than that of the normal renal parenchyma (p < 0.001). No statistical association was found between ADC values and pathological features (location, p = 0.35; grade, p = 0.98; muscle-invasive disease, p = 0.76 and locally advanced stage, p = 0.57). CONCLUSION: DWI may be interesting tool for detecting UTUCs regarding the difference of ADC values between the tumours and surrounding healthy tissues. In regard to low frequency of UTUCs, the association of ADC values and histological characteristics need further investigations in a large prospective multi-institutional study. More... »

PAGES

13-19

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00345-012-0945-7

DOI

http://dx.doi.org/10.1007/s00345-012-0945-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042522261

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22996759


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Transitional Cell", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diffusion Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Pelvis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ureteral Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Nephro-urological Radiology, Claude Huriez Hospital, CHRU Lille, Universit\u00e9 Lille Nord de France, 1, Rue Michel Polonovski, 59037, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sufana Iancu", 
        "givenName": "A.", 
        "id": "sg:person.01262223535.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262223535.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Urology, Claude Huriez Hospital, CHRU Lille, Universit\u00e9 Lille Nord de France, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Colin", 
        "givenName": "P.", 
        "id": "sg:person.01353512175.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353512175.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Nephro-urological Radiology, Claude Huriez Hospital, CHRU Lille, Universit\u00e9 Lille Nord de France, 1, Rue Michel Polonovski, 59037, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Puech", 
        "givenName": "P.", 
        "id": "sg:person.0665322662.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665322662.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Urology, Claude Huriez Hospital, CHRU Lille, Universit\u00e9 Lille Nord de France, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Villers", 
        "givenName": "A.", 
        "id": "sg:person.014702165417.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014702165417.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Urology, Claude Huriez Hospital, CHRU Lille, Universit\u00e9 Lille Nord de France, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ouzzane", 
        "givenName": "A.", 
        "id": "sg:person.01303340602.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01303340602.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Urology, Claude Huriez Hospital, CHRU Lille, Universit\u00e9 Lille Nord de France, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fantoni", 
        "givenName": "J. C.", 
        "id": "sg:person.01106574463.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106574463.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pathology, Biology and Pathology Center, CHRU Lille, Universit\u00e9 Lille Nord de France, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Leroy", 
        "givenName": "X.", 
        "id": "sg:person.0623452306.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623452306.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Nephro-urological Radiology, Claude Huriez Hospital, CHRU Lille, Universit\u00e9 Lille Nord de France, 1, Rue Michel Polonovski, 59037, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lemaitre", 
        "givenName": "L.", 
        "id": "sg:person.0776336307.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776336307.46"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.juro.2010.03.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002859580"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-011-2174-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004129978", 
          "https://doi.org/10.1007/s00330-011-2174-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00345-009-0494-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013113140", 
          "https://doi.org/10.1007/s00345-009-0494-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00345-009-0494-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013113140", 
          "https://doi.org/10.1007/s00345-009-0494-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2463/mrms.6.211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013968035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.juro.2010.03.142", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013991089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.2472070798", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015173944"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmri.22117", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017116511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmri.22117", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017116511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-011-2220-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018175402", 
          "https://doi.org/10.1007/s00330-011-2220-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/rg.256045517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019384944"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.2511080873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024533101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.eururo.2010.12.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025705384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.11110474", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026693762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-008-1228-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033430043", 
          "https://doi.org/10.1007/s00330-008-1228-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-008-1228-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033430043", 
          "https://doi.org/10.1007/s00330-008-1228-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s1677-55382010000100004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034035944"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00330-006-0547-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034178434", 
          "https://doi.org/10.1007/s00330-006-0547-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1442-2042.2007.01950.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048597194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1464-410x.2012.10960.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049664729"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1259/bjr/33169417", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064569108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.05.1918", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069297959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.06.1403", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069298296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.10.6299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069301523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2214/ajr.11.6861", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069301785"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074700508", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02841850802411857", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077813741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02841850802411857", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077813741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiology.209.1.9769826", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083328591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/9780471420194.tnmc43.pub2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086662930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/9780471420194.tnmc43.pub2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086662930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/9780471420194.tnmc43.pub2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086662930"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-02", 
    "datePublishedReg": "2013-02-01", 
    "description": "PURPOSE: To evaluate utility of diffusion-weighted magnetic resonance imaging (DWI) to detect and predict the histological characteristics of upper urinary tract urothelial carcinomas (UTUCs).\nMATERIALS AND METHODS: We retrospectively evaluated 20 suspicious lesions from 19 patients. MRI study included conventional sequences and DWI with apparent diffusion coefficient (ADC) maps calculated between b\u00a0=\u00a00 and b\u00a0=\u00a01,000. ADC values were measured within two different regions of interest (ROI): a small identical ROI placed in the most restrictive part of the tumour and a larger ROI covering two-thirds of the mass surface. The mean ADC values of the tumours were compared with that of normal renal parenchyma using an unpaired Student's t test. Association between ADC values and histological features was tested using non-parametric tests.\nRESULTS: Overall, 18 tumours were confirmed histologically as UTUCs. DWI failed to detect two cases of UTUCs (one CIS and one small tumour of 5\u00a0mm). There was no statistically significant difference in ADC values measured with the small or large ROI (p\u00a0=\u00a00.134). The mean ADC value of UTUC was significantly lower than that of the normal renal parenchyma (p\u00a0<\u00a00.001). No statistical association was found between ADC values and pathological features (location, p\u00a0=\u00a00.35; grade, p\u00a0=\u00a00.98; muscle-invasive disease, p\u00a0=\u00a00.76 and locally advanced stage, p\u00a0=\u00a00.57).\nCONCLUSION: DWI may be interesting tool for detecting UTUCs regarding the difference of ADC values between the tumours and surrounding healthy tissues. In regard to low frequency of UTUCs, the association of ADC values and histological characteristics need further investigations in a large prospective multi-institutional study.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00345-012-0945-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1094127", 
        "issn": [
          "0724-4983", 
          "1433-8726"
        ], 
        "name": "World Journal of Urology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "31"
      }
    ], 
    "name": "Significance of ADC value for detection and characterization of urothelial carcinoma of upper urinary tract using diffusion-weighted MRI", 
    "pagination": "13-19", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ca8d4c09ce0f5b132187b6ac86379c775efb1abdbc4c1667c4585b8563d7282c"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22996759"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8307716"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00345-012-0945-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1042522261"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00345-012-0945-7", 
      "https://app.dimensions.ai/details/publication/pub.1042522261"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:10", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000515.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00345-012-0945-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00345-012-0945-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00345-012-0945-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00345-012-0945-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00345-012-0945-7'


 

This table displays all metadata directly associated to this object as RDF triples.

261 TRIPLES      21 PREDICATES      67 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00345-012-0945-7 schema:about N205de21798344a9a904236c36f2b68f2
2 N488569b4dea7466c83a1427579a35ea7
3 N699c29ea6f0046b5894cd7053530cc56
4 N87a638894d1340df81c72b612775ea26
5 N9bb248ea4ac34cbf95d94aa0e258d42c
6 Naed8fe8e2560441091d07e3d6246444e
7 Nbf38f9b0f9d34c5a98cc8cc8846daadf
8 Nc908595a84a847aba5078d5a7ce04045
9 Nd8e00ed94d0a4674aab73af52b8570a5
10 Nefc5e0adc873431eaeb7c5441ddec032
11 Nf6a7116f0d38471693aaa4a022f3bf23
12 Nfcb671bad23340ca99cac954a1e56de1
13 anzsrc-for:11
14 anzsrc-for:1112
15 schema:author N0eb060a5a5ca41de85f291b23010c88e
16 schema:citation sg:pub.10.1007/s00330-006-0547-0
17 sg:pub.10.1007/s00330-008-1228-y
18 sg:pub.10.1007/s00330-011-2174-7
19 sg:pub.10.1007/s00330-011-2220-5
20 sg:pub.10.1007/s00345-009-0494-x
21 https://app.dimensions.ai/details/publication/pub.1074700508
22 https://doi.org/10.1002/9780471420194.tnmc43.pub2
23 https://doi.org/10.1002/jmri.22117
24 https://doi.org/10.1016/j.eururo.2010.12.042
25 https://doi.org/10.1016/j.juro.2010.03.030
26 https://doi.org/10.1016/j.juro.2010.03.142
27 https://doi.org/10.1080/02841850802411857
28 https://doi.org/10.1111/j.1442-2042.2007.01950.x
29 https://doi.org/10.1111/j.1464-410x.2012.10960.x
30 https://doi.org/10.1148/radiol.11110474
31 https://doi.org/10.1148/radiol.2472070798
32 https://doi.org/10.1148/radiol.2511080873
33 https://doi.org/10.1148/radiology.209.1.9769826
34 https://doi.org/10.1148/rg.256045517
35 https://doi.org/10.1259/bjr/33169417
36 https://doi.org/10.1590/s1677-55382010000100004
37 https://doi.org/10.2214/ajr.05.1918
38 https://doi.org/10.2214/ajr.06.1403
39 https://doi.org/10.2214/ajr.10.6299
40 https://doi.org/10.2214/ajr.11.6861
41 https://doi.org/10.2463/mrms.6.211
42 schema:datePublished 2013-02
43 schema:datePublishedReg 2013-02-01
44 schema:description PURPOSE: To evaluate utility of diffusion-weighted magnetic resonance imaging (DWI) to detect and predict the histological characteristics of upper urinary tract urothelial carcinomas (UTUCs). MATERIALS AND METHODS: We retrospectively evaluated 20 suspicious lesions from 19 patients. MRI study included conventional sequences and DWI with apparent diffusion coefficient (ADC) maps calculated between b = 0 and b = 1,000. ADC values were measured within two different regions of interest (ROI): a small identical ROI placed in the most restrictive part of the tumour and a larger ROI covering two-thirds of the mass surface. The mean ADC values of the tumours were compared with that of normal renal parenchyma using an unpaired Student's t test. Association between ADC values and histological features was tested using non-parametric tests. RESULTS: Overall, 18 tumours were confirmed histologically as UTUCs. DWI failed to detect two cases of UTUCs (one CIS and one small tumour of 5 mm). There was no statistically significant difference in ADC values measured with the small or large ROI (p = 0.134). The mean ADC value of UTUC was significantly lower than that of the normal renal parenchyma (p < 0.001). No statistical association was found between ADC values and pathological features (location, p = 0.35; grade, p = 0.98; muscle-invasive disease, p = 0.76 and locally advanced stage, p = 0.57). CONCLUSION: DWI may be interesting tool for detecting UTUCs regarding the difference of ADC values between the tumours and surrounding healthy tissues. In regard to low frequency of UTUCs, the association of ADC values and histological characteristics need further investigations in a large prospective multi-institutional study.
45 schema:genre research_article
46 schema:inLanguage en
47 schema:isAccessibleForFree false
48 schema:isPartOf N80cccb01cc6b41e2859cbacd71471272
49 Ne97497d130dc4987bf9dc436e5c202dc
50 sg:journal.1094127
51 schema:name Significance of ADC value for detection and characterization of urothelial carcinoma of upper urinary tract using diffusion-weighted MRI
52 schema:pagination 13-19
53 schema:productId N37cc3620fb1a4c2b9062ffa63efd9194
54 N6d16872ac6064c939010240a05f7c504
55 N88935039a0564cb485624e6082a5e74c
56 N8f4cb25407544f849974d98bf26cccc9
57 Na67823b773824570a0912e8517b97f00
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042522261
59 https://doi.org/10.1007/s00345-012-0945-7
60 schema:sdDatePublished 2019-04-10T14:10
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher N193f383ede434dfbbd35bcaa3537f0af
63 schema:url http://link.springer.com/10.1007%2Fs00345-012-0945-7
64 sgo:license sg:explorer/license/
65 sgo:sdDataset articles
66 rdf:type schema:ScholarlyArticle
67 N02edba20067f4775a8f0e321a64977b8 rdf:first sg:person.01106574463.98
68 rdf:rest Nbaad885a0c4f4a68a62b681895c0f5e5
69 N0eb060a5a5ca41de85f291b23010c88e rdf:first sg:person.01262223535.22
70 rdf:rest N468666ec9da44fbdb4a9edadd4915fff
71 N1430810bfbe54ef88dca0eb4e425920b schema:name Department of Urology, Claude Huriez Hospital, CHRU Lille, Université Lille Nord de France, Lille, France
72 rdf:type schema:Organization
73 N193f383ede434dfbbd35bcaa3537f0af schema:name Springer Nature - SN SciGraph project
74 rdf:type schema:Organization
75 N1b153d9279644dd889c002421c82a549 schema:name Department of Urology, Claude Huriez Hospital, CHRU Lille, Université Lille Nord de France, Lille, France
76 rdf:type schema:Organization
77 N205de21798344a9a904236c36f2b68f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Ureteral Neoplasms
79 rdf:type schema:DefinedTerm
80 N2fe64cacba19456bb8c534c3eb984a9f schema:name Department of Nephro-urological Radiology, Claude Huriez Hospital, CHRU Lille, Université Lille Nord de France, 1, Rue Michel Polonovski, 59037, Lille, France
81 rdf:type schema:Organization
82 N37cc3620fb1a4c2b9062ffa63efd9194 schema:name dimensions_id
83 schema:value pub.1042522261
84 rdf:type schema:PropertyValue
85 N468666ec9da44fbdb4a9edadd4915fff rdf:first sg:person.01353512175.13
86 rdf:rest Ne37c8de53bf14200a7ebe9f4d0f13422
87 N488569b4dea7466c83a1427579a35ea7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Humans
89 rdf:type schema:DefinedTerm
90 N699c29ea6f0046b5894cd7053530cc56 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Aged, 80 and over
92 rdf:type schema:DefinedTerm
93 N6cec0665dcd841c0b5844c0d374d2024 schema:name Department of Urology, Claude Huriez Hospital, CHRU Lille, Université Lille Nord de France, Lille, France
94 rdf:type schema:Organization
95 N6d16872ac6064c939010240a05f7c504 schema:name readcube_id
96 schema:value ca8d4c09ce0f5b132187b6ac86379c775efb1abdbc4c1667c4585b8563d7282c
97 rdf:type schema:PropertyValue
98 N7e4c8412f9cd42839a821e7979a8c275 rdf:first sg:person.01303340602.06
99 rdf:rest N02edba20067f4775a8f0e321a64977b8
100 N80cccb01cc6b41e2859cbacd71471272 schema:issueNumber 1
101 rdf:type schema:PublicationIssue
102 N87a638894d1340df81c72b612775ea26 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Aged
104 rdf:type schema:DefinedTerm
105 N88935039a0564cb485624e6082a5e74c schema:name pubmed_id
106 schema:value 22996759
107 rdf:type schema:PropertyValue
108 N8f44706a544246a8a9f61969be3edd40 schema:name Department of Nephro-urological Radiology, Claude Huriez Hospital, CHRU Lille, Université Lille Nord de France, 1, Rue Michel Polonovski, 59037, Lille, France
109 rdf:type schema:Organization
110 N8f4cb25407544f849974d98bf26cccc9 schema:name doi
111 schema:value 10.1007/s00345-012-0945-7
112 rdf:type schema:PropertyValue
113 N98f9509780ff4a2bbf80fce5209721c6 schema:name Department of Nephro-urological Radiology, Claude Huriez Hospital, CHRU Lille, Université Lille Nord de France, 1, Rue Michel Polonovski, 59037, Lille, France
114 rdf:type schema:Organization
115 N9bb248ea4ac34cbf95d94aa0e258d42c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Middle Aged
117 rdf:type schema:DefinedTerm
118 Na67823b773824570a0912e8517b97f00 schema:name nlm_unique_id
119 schema:value 8307716
120 rdf:type schema:PropertyValue
121 Na7db347161044d8d9113259d21a0468c rdf:first sg:person.0776336307.46
122 rdf:rest rdf:nil
123 Naed8fe8e2560441091d07e3d6246444e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Male
125 rdf:type schema:DefinedTerm
126 Nb896cb6c58794caa86be56ecf2cbf7ac rdf:first sg:person.014702165417.69
127 rdf:rest N7e4c8412f9cd42839a821e7979a8c275
128 Nbaad885a0c4f4a68a62b681895c0f5e5 rdf:first sg:person.0623452306.85
129 rdf:rest Na7db347161044d8d9113259d21a0468c
130 Nbf38f9b0f9d34c5a98cc8cc8846daadf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Kidney Pelvis
132 rdf:type schema:DefinedTerm
133 Nc4c28a4bcbb7435b84e0bb2bbff30f1e schema:name Department of Urology, Claude Huriez Hospital, CHRU Lille, Université Lille Nord de France, Lille, France
134 rdf:type schema:Organization
135 Nc908595a84a847aba5078d5a7ce04045 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Diffusion Magnetic Resonance Imaging
137 rdf:type schema:DefinedTerm
138 Nd8e00ed94d0a4674aab73af52b8570a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Carcinoma, Transitional Cell
140 rdf:type schema:DefinedTerm
141 Ne37c8de53bf14200a7ebe9f4d0f13422 rdf:first sg:person.0665322662.12
142 rdf:rest Nb896cb6c58794caa86be56ecf2cbf7ac
143 Ne97497d130dc4987bf9dc436e5c202dc schema:volumeNumber 31
144 rdf:type schema:PublicationVolume
145 Nefc5e0adc873431eaeb7c5441ddec032 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Female
147 rdf:type schema:DefinedTerm
148 Nf6a7116f0d38471693aaa4a022f3bf23 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Kidney Neoplasms
150 rdf:type schema:DefinedTerm
151 Nfb4a636e92b04ee09f6c77b2ab55c218 schema:name Department of Pathology, Biology and Pathology Center, CHRU Lille, Université Lille Nord de France, Lille, France
152 rdf:type schema:Organization
153 Nfcb671bad23340ca99cac954a1e56de1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Retrospective Studies
155 rdf:type schema:DefinedTerm
156 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
157 schema:name Medical and Health Sciences
158 rdf:type schema:DefinedTerm
159 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
160 schema:name Oncology and Carcinogenesis
161 rdf:type schema:DefinedTerm
162 sg:journal.1094127 schema:issn 0724-4983
163 1433-8726
164 schema:name World Journal of Urology
165 rdf:type schema:Periodical
166 sg:person.01106574463.98 schema:affiliation N1430810bfbe54ef88dca0eb4e425920b
167 schema:familyName Fantoni
168 schema:givenName J. C.
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106574463.98
170 rdf:type schema:Person
171 sg:person.01262223535.22 schema:affiliation N8f44706a544246a8a9f61969be3edd40
172 schema:familyName Sufana Iancu
173 schema:givenName A.
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262223535.22
175 rdf:type schema:Person
176 sg:person.01303340602.06 schema:affiliation Nc4c28a4bcbb7435b84e0bb2bbff30f1e
177 schema:familyName Ouzzane
178 schema:givenName A.
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01303340602.06
180 rdf:type schema:Person
181 sg:person.01353512175.13 schema:affiliation N1b153d9279644dd889c002421c82a549
182 schema:familyName Colin
183 schema:givenName P.
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353512175.13
185 rdf:type schema:Person
186 sg:person.014702165417.69 schema:affiliation N6cec0665dcd841c0b5844c0d374d2024
187 schema:familyName Villers
188 schema:givenName A.
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014702165417.69
190 rdf:type schema:Person
191 sg:person.0623452306.85 schema:affiliation Nfb4a636e92b04ee09f6c77b2ab55c218
192 schema:familyName Leroy
193 schema:givenName X.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623452306.85
195 rdf:type schema:Person
196 sg:person.0665322662.12 schema:affiliation N2fe64cacba19456bb8c534c3eb984a9f
197 schema:familyName Puech
198 schema:givenName P.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665322662.12
200 rdf:type schema:Person
201 sg:person.0776336307.46 schema:affiliation N98f9509780ff4a2bbf80fce5209721c6
202 schema:familyName Lemaitre
203 schema:givenName L.
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776336307.46
205 rdf:type schema:Person
206 sg:pub.10.1007/s00330-006-0547-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034178434
207 https://doi.org/10.1007/s00330-006-0547-0
208 rdf:type schema:CreativeWork
209 sg:pub.10.1007/s00330-008-1228-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1033430043
210 https://doi.org/10.1007/s00330-008-1228-y
211 rdf:type schema:CreativeWork
212 sg:pub.10.1007/s00330-011-2174-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004129978
213 https://doi.org/10.1007/s00330-011-2174-7
214 rdf:type schema:CreativeWork
215 sg:pub.10.1007/s00330-011-2220-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018175402
216 https://doi.org/10.1007/s00330-011-2220-5
217 rdf:type schema:CreativeWork
218 sg:pub.10.1007/s00345-009-0494-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013113140
219 https://doi.org/10.1007/s00345-009-0494-x
220 rdf:type schema:CreativeWork
221 https://app.dimensions.ai/details/publication/pub.1074700508 schema:CreativeWork
222 https://doi.org/10.1002/9780471420194.tnmc43.pub2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086662930
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1002/jmri.22117 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017116511
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/j.eururo.2010.12.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025705384
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/j.juro.2010.03.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002859580
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1016/j.juro.2010.03.142 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013991089
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1080/02841850802411857 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077813741
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1111/j.1442-2042.2007.01950.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048597194
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1111/j.1464-410x.2012.10960.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049664729
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1148/radiol.11110474 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026693762
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1148/radiol.2472070798 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015173944
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1148/radiol.2511080873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024533101
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1148/radiology.209.1.9769826 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083328591
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1148/rg.256045517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019384944
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1259/bjr/33169417 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064569108
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1590/s1677-55382010000100004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034035944
251 rdf:type schema:CreativeWork
252 https://doi.org/10.2214/ajr.05.1918 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069297959
253 rdf:type schema:CreativeWork
254 https://doi.org/10.2214/ajr.06.1403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069298296
255 rdf:type schema:CreativeWork
256 https://doi.org/10.2214/ajr.10.6299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069301523
257 rdf:type schema:CreativeWork
258 https://doi.org/10.2214/ajr.11.6861 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069301785
259 rdf:type schema:CreativeWork
260 https://doi.org/10.2463/mrms.6.211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013968035
261 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...