The example of CaPSURE: lessons learned from a national disease registry View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-06

AUTHORS

Sima P. Porten, Matthew R. Cooperberg, Badrinath R. Konety, Peter R. Carroll

ABSTRACT

INTRODUCTION: Although randomized controlled trials (RCTs) remain the gold standard for determining evidence-based clinical practices, large disease registries that enroll large numbers of patients have become paramount as a relatively cost-effective additional tool. METHODS: We highlight the advantages of disease registries focusing on the example of prostate cancer and the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE™) registry. RESULTS: CaPSURE collects approximately 1,000 clinical and patient-reported variables, in over 13,000 men that are enrolled. Thus far, CaPSURE has yielded over 130 peer-reviewed publications, with several others in press, in key areas of risk migration, practice patterns, outcome prediction, and quality of life outcomes. CONCLUSIONS: Disease registries, like CaPSURE complement RCTs and CaPSURE, have provided a means to better understand many aspects of prostate cancer epidemiology, practice patterns, oncologic and HRQOL outcomes, and costs of care across populations. Specialized observational disease registries such as CaPSURE provide insight and have broad implications for disease management and policy. More... »

PAGES

265-271

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00345-011-0658-3

DOI

http://dx.doi.org/10.1007/s00345-011-0658-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021432806

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21347810


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