Prevalence and burden of overactive bladder in the United States View Full Text


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Article Info

DATE

2002-11-15

AUTHORS

W. Stewart, J. Van Rooyen, G. Cundiff, P. Abrams, A. Herzog, R. Corey, T. Hunt, A. Wein

ABSTRACT

.Context: the National Overactive BLadder Evaluation (NOBLE) Program was initiated to better understand the prevalence and burden of overactive bladder in a broad spectrum of the United States population. Objective: to estimate the prevalence of overactive bladder with and without urge incontinence in the US, assess variation in prevalence by sex and other factors, and measure individual burden. Design: US national telephone survey using a clinically validated interview and a follow-up nested study comparing overactive bladder cases to sex- and age-matched controls. Setting: noninstitutionalized US adult population. Participants: a sample of 5,204 adults ≥18 years of age and representative of the US population by sex, age, and geographical region. Main outcome measures: prevalence of overactive bladder with and without urge incontinence and risk factors for overactive bladder in the US. In the nested case-control study, SF-36, CES-D, and MOS sleep scores were used to assess impact. Results: the overall prevalence of overactive bladder was similar between men (16.0%) and women (16.9%), but sex-specific prevalence differed substantially by severity of symptoms. In women, prevalence of urge incontinence increased with age from 2.0% to 19% with a marked increase after 44 years of age, and in men, increased with age from 0.3% to 8.9% with a marked increase after 64 years of age. Across all age groups, overactive bladder without urge incontinence was more common in men than in women. Overactive bladder with and without urge incontinence was associated with clinically and significantly lower SF-36 quality-of-life scores, higher CES-D depression scores, and poorer quality of sleep than matched controls. Conclusions: the NOBLE studies do not support the commonly held notion that women are considerably more likely than men to have urgency-related bladder control problems. The overall prevalence of overactive bladder does not differ by sex; however, the severity and nature of symptom expression does differ. Sex-specific anatomic differences may increase the probability that overactive bladder is expressed as urge incontinence among women compared with men. Nonetheless, overactive bladder, with and without incontinence, has a clinically significant impact on quality-of-life, quality-of-sleep, and mental health, in both men and women. More... »

PAGES

327-336

Journal

TITLE

World Journal of Urology

ISSUE

6

VOLUME

20

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  • The Estrogen Impact On Overactive Bladder Syndrome: Female Pelvic Floor Microbiomes And Antimicrobial Peptides
  • Investigation Of The Effect Of The Female Urinary Microbiome On Incontinence
  • Antimuscarinic Medication For Urgency Urinary Incontinence In Women With Dual Incontinence (Darifenacin For Treatment Of Women With Dual Incontinence)
  • Standard Injections Versus Reduced Injections For Intravesical Onabotulinumtoxina For Treatment Of Idiopathic And Neurogenic Overactive Bladder: A Randomized Trial
  • 'The Experience Sampling Method (Esm): A Real-Time Patient-Reported Outcome Measure For Symptom Assessment In Patients With Overactive Bladder Syndrome.'
  • Age-Specific Prevalence And Comparisons Of Urodynamics And Bladder Diary Between Overactive Bladder-Wet And -Dry Women Based On Bladder Diary
  • The Effect Of Information, Motivation, Behavioral Skills Model On Urinary Incontinence And Quality Of Life In Men With Overactive Bladder: A Randomized Controlled Trial
  • Efficacy Of Botulinum Toxin A Intradetrusor Injections For The Treatment Of Non-Neurogenic Urinary Urge Incontinence- A Randomized Double-Blind Control Trial
  • Comparisons Of Health-Related Quality Of Life Between Overactive Bladder-Wet And -Dry Women Based On Bladder Diary
  • Pilot Study: Mirabegron For The Treatment Of Pain Motivated Urinary Frequency And Urgency In Women, An Open Label Study With Dose Escalation
  • The Applicability Of The Oab Assessment Tool For Evaluation Of Treatment Efficacy Of Overactive Bladder.
  • Prevalence And Risk Factors Of Nocturnal Polyuria In Female Overactive Bladder Syndrome
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00345-002-0301-4

    DOI

    http://dx.doi.org/10.1007/s00345-002-0301-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1075301922

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12811491


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