A new mouse model for infantile neuroaxonal dystrophy,inad mouse, maps to mouse Chromosome 1 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-02

AUTHORS

Yoshibumi Matsushima, Tateki Kikuchi, Hisae Kikuchi, Nobutsune Ichihara, Akira Ishikawa, Yasushi Ishijima, Masayoshi Tachibana

ABSTRACT

Infantile neuroaxonal dystrophy (INAD) is a rare autosomal recessive hereditary neurodegenerative disease of humans. So far, no responsible gene has been cloned or mapped to any chromosome. For chromosome mapping and positional cloning of the responsible gene, establishment of an animal model would be useful. Here we describe a new mouse model for INAD, named inad mouse. In this mouse, the phenotype is inherited in an autosomal recessive manner, symptoms occur in the infantile period, and the mouse dies before sexual maturity. Axonal dystrophic change appearing as spheroid bodies in central and peripheral nervous system was observed. These features more closely resembled human INAD than did those of the gad mouse, the traditional mouse model for INAD. Linkage analysis linked the inad gene to mouse Chromosome 1, with the highest LOD score (=128.6) at the D1Mit45 marker, and haplotype study localized the inad gene to a 7.5-Mb region between D1Mit84 and D1Mit25. In this linkage area some 60 genes exist: Mutation of one of these 60 genes is likely responsible for the inad mouse phenotype. Our preliminary mutation analysis in 15 genes examining the nucleotide sequence of exons of these genes did not find any sequence difference between inad mouse and C57BL/6 mouse. More... »

PAGES

73-78

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00335-004-3017-5

DOI

http://dx.doi.org/10.1007/s00335-004-3017-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031444352

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15859351


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Mammalian", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Mutational Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Recessive", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lod Score", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle, Skeletal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuroaxonal Dystrophies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pedigree", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Saitama Cancer Center, Research Institute for Clinical Oncology, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416695.9", 
          "name": [
            "Saitama Cancer Center, Research Institute for Clinical Oncology, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsushima", 
        "givenName": "Yoshibumi", 
        "id": "sg:person.01171406737.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171406737.93"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Center of Neurology and Psychiatry, Kodaira, Japan", 
          "id": "http://www.grid.ac/institutes/grid.419280.6", 
          "name": [
            "National Center of Neurology and Psychiatry, Kodaira, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kikuchi", 
        "givenName": "Tateki", 
        "id": "sg:person.011064726622.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011064726622.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Center of Neurology and Psychiatry, Kodaira, Japan", 
          "id": "http://www.grid.ac/institutes/grid.419280.6", 
          "name": [
            "National Center of Neurology and Psychiatry, Kodaira, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kikuchi", 
        "givenName": "Hisae", 
        "id": "sg:person.011050436522.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011050436522.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Veterinary Medicine, Azabu University, Sagamihara, Japan", 
          "id": "http://www.grid.ac/institutes/grid.252643.4", 
          "name": [
            "National Center of Neurology and Psychiatry, Kodaira, Japan", 
            "School of Veterinary Medicine, Azabu University, Sagamihara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ichihara", 
        "givenName": "Nobutsune", 
        "id": "sg:person.01123232546.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123232546.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory of Animal Genetics, Division of Applied Genetics and Physiology, Graduate School of Bioagricultural Science, Nagoya University, Nagoya, Japan", 
          "id": "http://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "Laboratory of Animal Genetics, Division of Applied Genetics and Physiology, Graduate School of Bioagricultural Science, Nagoya University, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishikawa", 
        "givenName": "Akira", 
        "id": "sg:person.014330414221.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014330414221.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Genome Science Branch, Center for Bioresource-based Research, Brain Research Institute, Niigata University, 1 Asahimachi, 951 8510, Niigata, Japan", 
          "id": "http://www.grid.ac/institutes/grid.260975.f", 
          "name": [
            "Rational Evolutionary Design of Advanced Biomolecules (REDS) Group/Japan Science and Technology Agency (JST), Saitama Small Enterprise Promotion Corporation, Saitama, Japan", 
            "Genome Science Branch, Center for Bioresource-based Research, Brain Research Institute, Niigata University, 1 Asahimachi, 951 8510, Niigata, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishijima", 
        "givenName": "Yasushi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Genome Science Branch, Center for Bioresource-based Research, Brain Research Institute, Niigata University, 1 Asahimachi, 951 8510, Niigata, Japan", 
          "id": "http://www.grid.ac/institutes/grid.260975.f", 
          "name": [
            "Saitama Cancer Center, Research Institute for Clinical Oncology, Saitama, Japan", 
            "Rational Evolutionary Design of Advanced Biomolecules (REDS) Group/Japan Science and Technology Agency (JST), Saitama Small Enterprise Promotion Corporation, Saitama, Japan", 
            "Genome Science Branch, Center for Bioresource-based Research, Brain Research Institute, Niigata University, 1 Asahimachi, 951 8510, Niigata, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tachibana", 
        "givenName": "Masayoshi", 
        "id": "sg:person.01054506435.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054506435.18"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00335-001-1016-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032730610", 
          "https://doi.org/10.1007/s00335-001-1016-3"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2005-02", 
    "datePublishedReg": "2005-02-01", 
    "description": "Infantile neuroaxonal dystrophy (INAD) is a rare autosomal recessive hereditary neurodegenerative disease of humans. So far, no responsible gene has been cloned or mapped to any chromosome. For chromosome mapping and positional cloning of the responsible gene, establishment of an animal model would be useful. Here we describe a new mouse model for INAD, named inad mouse. In this mouse, the phenotype is inherited in an autosomal recessive manner, symptoms occur in the infantile period, and the mouse dies before sexual maturity. Axonal dystrophic change appearing as spheroid bodies in central and peripheral nervous system was observed. These features more closely resembled human INAD than did those of the gad mouse, the traditional mouse model for INAD. Linkage analysis linked the inad gene to mouse Chromosome 1, with the highest LOD score (=128.6) at the D1Mit45 marker, and haplotype study localized the inad gene to a 7.5-Mb region between D1Mit84 and D1Mit25. In this linkage area some 60 genes exist: Mutation of one of these 60 genes is likely responsible for the inad mouse phenotype. Our preliminary mutation analysis in 15 genes examining the nucleotide sequence of exons of these genes did not find any sequence difference between inad mouse and C57BL/6 mouse.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00335-004-3017-5", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1100928", 
        "issn": [
          "0938-8990", 
          "1432-1777"
        ], 
        "name": "Mammalian Genome", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "keywords": [
      "inad gene", 
      "chromosome 1", 
      "responsible gene", 
      "mouse chromosome 1", 
      "human infantile neuroaxonal dystrophy", 
      "preliminary mutation analysis", 
      "traditional mouse models", 
      "hereditary neurodegenerative disease", 
      "new mouse model", 
      "chromosome mapping", 
      "positional cloning", 
      "highest LOD score", 
      "nucleotide sequence", 
      "sequence differences", 
      "genes", 
      "infantile neuroaxonal dystrophy", 
      "autosomal recessive manner", 
      "linkage analysis", 
      "mouse phenotype", 
      "mouse model", 
      "gad mice", 
      "sexual maturity", 
      "linkage areas", 
      "recessive manner", 
      "LOD score", 
      "neurodegenerative diseases", 
      "spheroid bodies", 
      "mutation analysis", 
      "peripheral nervous system", 
      "phenotype", 
      "haplotype studies", 
      "chromosomes", 
      "cloning", 
      "neuroaxonal dystrophy", 
      "exons", 
      "nervous system", 
      "mice", 
      "mutations", 
      "sequence", 
      "dystrophy", 
      "animal models", 
      "establishment", 
      "markers", 
      "humans", 
      "maturity", 
      "manner", 
      "region", 
      "mapping", 
      "analysis", 
      "dystrophic changes", 
      "changes", 
      "body", 
      "maps", 
      "disease", 
      "C57BL/6 mice", 
      "study", 
      "differences", 
      "model", 
      "area", 
      "features", 
      "system", 
      "period", 
      "symptoms", 
      "scores", 
      "infantile period", 
      "rare autosomal recessive hereditary neurodegenerative disease", 
      "autosomal recessive hereditary neurodegenerative disease", 
      "recessive hereditary neurodegenerative disease", 
      "inad mouse", 
      "Axonal dystrophic change", 
      "D1Mit45 marker", 
      "D1Mit84", 
      "D1Mit25", 
      "inad mouse phenotype"
    ], 
    "name": "A new mouse model for infantile neuroaxonal dystrophy,inad mouse, maps to mouse Chromosome 1", 
    "pagination": "73-78", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1031444352"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00335-004-3017-5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15859351"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00335-004-3017-5", 
      "https://app.dimensions.ai/details/publication/pub.1031444352"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:14", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_406.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00335-004-3017-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00335-004-3017-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00335-004-3017-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00335-004-3017-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00335-004-3017-5'


 

This table displays all metadata directly associated to this object as RDF triples.

244 TRIPLES      22 PREDICATES      114 URIs      105 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00335-004-3017-5 schema:about N22bdeaa5673c4bbb83e59f4c47cdeca3
2 N3888b4b456ff4d94a571b170a61485ea
3 N4fb5f1f8c9b54ae3ba4b89b377290c53
4 N5b84c89ef4634fcbb0c7a03d1a85101a
5 N64770fbfc2a94c4aa2806a8196b927d8
6 N6751838405ae4a45a795db36d09809a9
7 N8b5c55f08bc546a385ebedea51f004f0
8 Nb311f8864827411d86b59e9d17350e79
9 Nc460295d7c0a4184b009b319752bbf97
10 Nc6bc7d8e32dd4e53938ff113c408dd9f
11 Ne89e4bd6ee5443658e4963f200130128
12 Nfdc03cb0e7f944989aab8e629a919577
13 anzsrc-for:06
14 anzsrc-for:0604
15 schema:author Nde8b898efdfa442184665a49c142e6c5
16 schema:citation sg:pub.10.1007/s00335-001-1016-3
17 schema:datePublished 2005-02
18 schema:datePublishedReg 2005-02-01
19 schema:description Infantile neuroaxonal dystrophy (INAD) is a rare autosomal recessive hereditary neurodegenerative disease of humans. So far, no responsible gene has been cloned or mapped to any chromosome. For chromosome mapping and positional cloning of the responsible gene, establishment of an animal model would be useful. Here we describe a new mouse model for INAD, named inad mouse. In this mouse, the phenotype is inherited in an autosomal recessive manner, symptoms occur in the infantile period, and the mouse dies before sexual maturity. Axonal dystrophic change appearing as spheroid bodies in central and peripheral nervous system was observed. These features more closely resembled human INAD than did those of the gad mouse, the traditional mouse model for INAD. Linkage analysis linked the inad gene to mouse Chromosome 1, with the highest LOD score (=128.6) at the D1Mit45 marker, and haplotype study localized the inad gene to a 7.5-Mb region between D1Mit84 and D1Mit25. In this linkage area some 60 genes exist: Mutation of one of these 60 genes is likely responsible for the inad mouse phenotype. Our preliminary mutation analysis in 15 genes examining the nucleotide sequence of exons of these genes did not find any sequence difference between inad mouse and C57BL/6 mouse.
20 schema:genre article
21 schema:inLanguage en
22 schema:isAccessibleForFree false
23 schema:isPartOf N3d2b0651f58f43a9bb604c6f0036a1be
24 Na1dd879f6acb469cb100bdf01083b14c
25 sg:journal.1100928
26 schema:keywords Axonal dystrophic change
27 C57BL/6 mice
28 D1Mit25
29 D1Mit45 marker
30 D1Mit84
31 LOD score
32 analysis
33 animal models
34 area
35 autosomal recessive hereditary neurodegenerative disease
36 autosomal recessive manner
37 body
38 changes
39 chromosome 1
40 chromosome mapping
41 chromosomes
42 cloning
43 differences
44 disease
45 dystrophic changes
46 dystrophy
47 establishment
48 exons
49 features
50 gad mice
51 genes
52 haplotype studies
53 hereditary neurodegenerative disease
54 highest LOD score
55 human infantile neuroaxonal dystrophy
56 humans
57 inad gene
58 inad mouse
59 inad mouse phenotype
60 infantile neuroaxonal dystrophy
61 infantile period
62 linkage analysis
63 linkage areas
64 manner
65 mapping
66 maps
67 markers
68 maturity
69 mice
70 model
71 mouse chromosome 1
72 mouse model
73 mouse phenotype
74 mutation analysis
75 mutations
76 nervous system
77 neuroaxonal dystrophy
78 neurodegenerative diseases
79 new mouse model
80 nucleotide sequence
81 period
82 peripheral nervous system
83 phenotype
84 positional cloning
85 preliminary mutation analysis
86 rare autosomal recessive hereditary neurodegenerative disease
87 recessive hereditary neurodegenerative disease
88 recessive manner
89 region
90 responsible gene
91 scores
92 sequence
93 sequence differences
94 sexual maturity
95 spheroid bodies
96 study
97 symptoms
98 system
99 traditional mouse models
100 schema:name A new mouse model for infantile neuroaxonal dystrophy,inad mouse, maps to mouse Chromosome 1
101 schema:pagination 73-78
102 schema:productId N72e86edabdbc4546b22a6ece31861810
103 N8e580b55eaed45c6ad48a41fdd11d2a7
104 N941ab7aee32745e4b53cbc1d761cbf55
105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031444352
106 https://doi.org/10.1007/s00335-004-3017-5
107 schema:sdDatePublished 2022-01-01T18:14
108 schema:sdLicense https://scigraph.springernature.com/explorer/license/
109 schema:sdPublisher N09b6609241974825b4c579149044bb58
110 schema:url https://doi.org/10.1007/s00335-004-3017-5
111 sgo:license sg:explorer/license/
112 sgo:sdDataset articles
113 rdf:type schema:ScholarlyArticle
114 N09b6609241974825b4c579149044bb58 schema:name Springer Nature - SN SciGraph project
115 rdf:type schema:Organization
116 N22bdeaa5673c4bbb83e59f4c47cdeca3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Mice
118 rdf:type schema:DefinedTerm
119 N24ebfa73761f4c038bc000a033105a59 rdf:first N3233a4dc957d40079021a3f5cc438828
120 rdf:rest N5fad80e2900c499c833c9ab2a7abfdef
121 N3233a4dc957d40079021a3f5cc438828 schema:affiliation grid-institutes:grid.260975.f
122 schema:familyName Ishijima
123 schema:givenName Yasushi
124 rdf:type schema:Person
125 N3888b4b456ff4d94a571b170a61485ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Lod Score
127 rdf:type schema:DefinedTerm
128 N3af6434f2308411f8449d5258808c3af rdf:first sg:person.01123232546.59
129 rdf:rest N9882d1c72b6f491da1cebaed0167175f
130 N3d2b0651f58f43a9bb604c6f0036a1be schema:volumeNumber 16
131 rdf:type schema:PublicationVolume
132 N4fb5f1f8c9b54ae3ba4b89b377290c53 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Brain
134 rdf:type schema:DefinedTerm
135 N5b84c89ef4634fcbb0c7a03d1a85101a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Chromosomes, Mammalian
137 rdf:type schema:DefinedTerm
138 N5fad80e2900c499c833c9ab2a7abfdef rdf:first sg:person.01054506435.18
139 rdf:rest rdf:nil
140 N64770fbfc2a94c4aa2806a8196b927d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Animals
142 rdf:type schema:DefinedTerm
143 N6751838405ae4a45a795db36d09809a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Pedigree
145 rdf:type schema:DefinedTerm
146 N72e86edabdbc4546b22a6ece31861810 schema:name dimensions_id
147 schema:value pub.1031444352
148 rdf:type schema:PropertyValue
149 N790a6acf5022468187f6c937a3856386 rdf:first sg:person.011050436522.60
150 rdf:rest N3af6434f2308411f8449d5258808c3af
151 N8b5c55f08bc546a385ebedea51f004f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Genes, Recessive
153 rdf:type schema:DefinedTerm
154 N8e580b55eaed45c6ad48a41fdd11d2a7 schema:name pubmed_id
155 schema:value 15859351
156 rdf:type schema:PropertyValue
157 N941ab7aee32745e4b53cbc1d761cbf55 schema:name doi
158 schema:value 10.1007/s00335-004-3017-5
159 rdf:type schema:PropertyValue
160 N9882d1c72b6f491da1cebaed0167175f rdf:first sg:person.014330414221.75
161 rdf:rest N24ebfa73761f4c038bc000a033105a59
162 Na1dd879f6acb469cb100bdf01083b14c schema:issueNumber 2
163 rdf:type schema:PublicationIssue
164 Nb311f8864827411d86b59e9d17350e79 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name DNA Mutational Analysis
166 rdf:type schema:DefinedTerm
167 Nc460295d7c0a4184b009b319752bbf97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Disease Models, Animal
169 rdf:type schema:DefinedTerm
170 Nc6bc7d8e32dd4e53938ff113c408dd9f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Neuroaxonal Dystrophies
172 rdf:type schema:DefinedTerm
173 Nde8b898efdfa442184665a49c142e6c5 rdf:first sg:person.01171406737.93
174 rdf:rest Nff84aa6c6f7448969a01055f3a73966d
175 Ne89e4bd6ee5443658e4963f200130128 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Muscle, Skeletal
177 rdf:type schema:DefinedTerm
178 Nfdc03cb0e7f944989aab8e629a919577 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Chromosome Mapping
180 rdf:type schema:DefinedTerm
181 Nff84aa6c6f7448969a01055f3a73966d rdf:first sg:person.011064726622.01
182 rdf:rest N790a6acf5022468187f6c937a3856386
183 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
184 schema:name Biological Sciences
185 rdf:type schema:DefinedTerm
186 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
187 schema:name Genetics
188 rdf:type schema:DefinedTerm
189 sg:journal.1100928 schema:issn 0938-8990
190 1432-1777
191 schema:name Mammalian Genome
192 schema:publisher Springer Nature
193 rdf:type schema:Periodical
194 sg:person.01054506435.18 schema:affiliation grid-institutes:grid.260975.f
195 schema:familyName Tachibana
196 schema:givenName Masayoshi
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054506435.18
198 rdf:type schema:Person
199 sg:person.011050436522.60 schema:affiliation grid-institutes:grid.419280.6
200 schema:familyName Kikuchi
201 schema:givenName Hisae
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011050436522.60
203 rdf:type schema:Person
204 sg:person.011064726622.01 schema:affiliation grid-institutes:grid.419280.6
205 schema:familyName Kikuchi
206 schema:givenName Tateki
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011064726622.01
208 rdf:type schema:Person
209 sg:person.01123232546.59 schema:affiliation grid-institutes:grid.252643.4
210 schema:familyName Ichihara
211 schema:givenName Nobutsune
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123232546.59
213 rdf:type schema:Person
214 sg:person.01171406737.93 schema:affiliation grid-institutes:grid.416695.9
215 schema:familyName Matsushima
216 schema:givenName Yoshibumi
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171406737.93
218 rdf:type schema:Person
219 sg:person.014330414221.75 schema:affiliation grid-institutes:grid.27476.30
220 schema:familyName Ishikawa
221 schema:givenName Akira
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014330414221.75
223 rdf:type schema:Person
224 sg:pub.10.1007/s00335-001-1016-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032730610
225 https://doi.org/10.1007/s00335-001-1016-3
226 rdf:type schema:CreativeWork
227 grid-institutes:grid.252643.4 schema:alternateName School of Veterinary Medicine, Azabu University, Sagamihara, Japan
228 schema:name National Center of Neurology and Psychiatry, Kodaira, Japan
229 School of Veterinary Medicine, Azabu University, Sagamihara, Japan
230 rdf:type schema:Organization
231 grid-institutes:grid.260975.f schema:alternateName Genome Science Branch, Center for Bioresource-based Research, Brain Research Institute, Niigata University, 1 Asahimachi, 951 8510, Niigata, Japan
232 schema:name Genome Science Branch, Center for Bioresource-based Research, Brain Research Institute, Niigata University, 1 Asahimachi, 951 8510, Niigata, Japan
233 Rational Evolutionary Design of Advanced Biomolecules (REDS) Group/Japan Science and Technology Agency (JST), Saitama Small Enterprise Promotion Corporation, Saitama, Japan
234 Saitama Cancer Center, Research Institute for Clinical Oncology, Saitama, Japan
235 rdf:type schema:Organization
236 grid-institutes:grid.27476.30 schema:alternateName Laboratory of Animal Genetics, Division of Applied Genetics and Physiology, Graduate School of Bioagricultural Science, Nagoya University, Nagoya, Japan
237 schema:name Laboratory of Animal Genetics, Division of Applied Genetics and Physiology, Graduate School of Bioagricultural Science, Nagoya University, Nagoya, Japan
238 rdf:type schema:Organization
239 grid-institutes:grid.416695.9 schema:alternateName Saitama Cancer Center, Research Institute for Clinical Oncology, Saitama, Japan
240 schema:name Saitama Cancer Center, Research Institute for Clinical Oncology, Saitama, Japan
241 rdf:type schema:Organization
242 grid-institutes:grid.419280.6 schema:alternateName National Center of Neurology and Psychiatry, Kodaira, Japan
243 schema:name National Center of Neurology and Psychiatry, Kodaira, Japan
244 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...