Practical guide to quantification of hepatic iron with MRI View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-08-07

AUTHORS

Benjamin Henninger, Jose Alustiza, Maciej Garbowski, Yves Gandon

ABSTRACT

Our intention is to demystify the MR quantification of hepatic iron (i.e., the liver iron concentration) and give you a step-by-step approach by answering the most pertinent questions. The following article should be more of a manual or guide for every radiologist than a classic review article, which just summarizes the literature. Furthermore, we provide important background information for professional communication with clinicians. The information regarding the physical background is reduced to a minimum. After reading this article, you should be able to perform adequate MR measurements of the LIC with 1.5-T or 3.0-T scanners.Key Points• MRI is widely accepted as the primary approach to non-invasively determine liver iron concentration (LIC).• This article is a guide for every radiologist to perform adequate MR measurements of the LIC.• When using R2* relaxometry, some points have to be considered to obtain correct measurements—all explained in this article. More... »

PAGES

383-393

References to SciGraph publications

  • 2010-07-30. An open-source software tool for the generation of relaxation time maps in magnetic resonance imaging in BMC MEDICAL IMAGING
  • 2016-06-22. Comparison between different software programs and post-processing techniques for the MRI quantification of liver iron concentration in thalassemia patients in LA RADIOLOGIA MEDICA
  • 2014-05-01. Diagnostic accuracy of dual-echo (in- and opposed-phase) T1-weighted gradient recalled echo for detection and grading of hepatic iron using quantitative and visual assessment in EUROPEAN RADIOLOGY
  • 2010-08-06. Liver iron concentration quantification by MRI: are recommended protocols accurate enough for clinical practice? in EUROPEAN RADIOLOGY
  • 2015-05-26. Retrospective comparison of gradient recalled echo R2* and spin-echo R2 magnetic resonance analysis methods for estimating liver iron content in children and adolescents in PEDIATRIC RADIOLOGY
  • 2010-03-24. Comparison of whole liver and small region-of-interest measurements of MRI liver R2* in children with iron overload in PEDIATRIC RADIOLOGY
  • 2014-06-10. Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan in JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
  • 2017-10-23. Agreement between manual relaxometry and semi-automated scanner-based multi-echo Dixon technique for measuring liver T2* in a pediatric and young adult population in PEDIATRIC RADIOLOGY
  • 2017-11-24. Non-invasive measurement of liver iron concentration using 3-Tesla magnetic resonance imaging: validation against biopsy in EUROPEAN RADIOLOGY
  • 2011-12-30. Quantification of iron concentration in the liver by MRI in INSIGHTS INTO IMAGING
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00330-019-06380-9

    DOI

    http://dx.doi.org/10.1007/s00330-019-06380-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1120188749

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/31392478


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