CT diagnosis of gallbladder adenomyomatosis: importance of enhancing mucosal epithelium, the “cotton ball sign” View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-09

AUTHORS

Hyun Kyung Yang, Jeong Min Lee, Mi Hye Yu, Sang Min Lee, Jinyoung Park, Na Young Han, Kyoungbun Lee, Jin-Young Jang, Joon Koo Han

ABSTRACT

OBJECTIVES: To determine the diagnostic value of the cotton ball sign and other CT features in patients with gallbladder (GB) wall thickenings (WTs). METHODS: Three blinded readers reviewed the preoperative CT and MR images of 101 patients with pathologically confirmed GB adenomyomatosis (GA) (n = 34) and other benign (n = 29), malignant (n = 41), and premalignant (n = 2) GBWTs. Three readers analysed the morphological features of GBWT and presence of the "cotton ball sign", defined as fuzzy grey dots in GBWT or a dotted outer border of the inner enhancing layer on contrast-enhanced (CE) CT. In addition, the "pearl necklace sign" on MR was analysed. RESULTS: In the GA group (n = 34), prevalence of the cotton ball sign and pearl necklace sign was 74% (25/34) and 44% (15/34), respectively. Presence of the cotton ball sign, smooth contour of the mucosa, double-layering enhancement, and enhancement degree weaker than the renal cortex on CT images were significant predictors of benign GBWT (p < 0.01). When differentiating GA from GB malignancy or premalignancy, accuracy of the cotton ball sign and pearl necklace sign was 81% (62/77) and 74% (57/77), respectively. CONCLUSION: The cotton ball sign on CE-CT showed higher sensitivity and comparable specificity to those of the pearl necklace sign in differentiating GA from malignancy. KEY POINTS: • Prevalence of the cotton ball sign on CT was 74% in gallbladder adenomyomatosis. • The cotton ball sign was useful in differentiating gallbladder adenomyomatosis from gallbladder cancer. • The cotton ball sign was more sensitive than the pearl necklace sign for adenomyomatosis diagnosis. More... »

PAGES

3573-3582

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00330-018-5412-4

DOI

http://dx.doi.org/10.1007/s00330-018-5412-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1103190978

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29633001


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00330-018-5412-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00330-018-5412-4'

Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00330-018-5412-4'


 

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317 schema:name Department of Radiology, Dongnam Institute of Radiological and Medical Sciences, Busan, Korea
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319 https://www.grid.ac/institutes/grid.488421.3 schema:alternateName Hallym University Sacred Heart Hospital
320 schema:name Department of Radiology, Hallym University Sacred Heart Hospital, Anyang, Gyeonggi-do, Korea
321 rdf:type schema:Organization
 




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