Repeatability of apparent diffusion coefficient and intravoxel incoherent motion parameters at 3.0 Tesla in orbital lesions View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-07-04

AUTHORS

Augustin Lecler, Julien Savatovsky, Daniel Balvay, Mathieu Zmuda, Jean-Claude Sadik, Olivier Galatoire, Frédérique Charbonneau, Olivier Bergès, Hervé Picard, Laure Fournier

ABSTRACT

ObjectivesTo evaluate repeatability of intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters in the orbit.MethodsFrom December 2015 to March 2016, 22 patients were scanned twice using an IVIM sequence with 15b values (0–2,000 s/mm2) at 3.0T. Two readers independently delineated regions of interest in an orbital mass and in different intra-orbital and extra-orbital structures. Short-term test-retest repeatability and inter-observer agreement were assessed using the intra-class correlation coefficient (ICC), the coefficient of variation (CV) and Bland-Altman limits of agreements (BA-LA).ResultsTest-retest repeatability of IVIM parameters in the orbital mass was satisfactory for ADC and D (mean CV 12% and 14%, ICC 95% and 93%), poor for f and D*(means CV 43% and 110%, ICC 90% and 65%). Inter-observer repeatability agreement was almost perfect in the orbital mass for all the IVIM parameters (ICC = 95%, 93%, 94% and 90% for ADC, D, f and D*, respectively).ConclusionsIVIM appeared to be a robust tool to measure D in orbital lesions with good repeatability, but this approach showed a poor repeatability of f and D*.Key Points• IVIM technique is feasible in the orbit.• IVIM has a good–acceptable repeatability of D (CV range 12–25 %).• IVIM interobserver repeatability agreement is excellent (ICC range 90–95 %).• f or D* provide higher test-retest and interobserver variabilities. More... »

PAGES

5094-5103

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00330-017-4933-6

DOI

http://dx.doi.org/10.1007/s00330-017-4933-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1090344582

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28677061


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